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xCas9 3.7 Citations (8)

Originally described in: Evolved Cas9 variants with broad PAM compatibility and high DNA specificity.
Hu JH, Miller SM, Geurts MH, Tang W, Chen L, Sun N, Zeina CM, Gao X, Rees HA, Lin Z, Liu DR Nature. 2018 Feb 28. pii: nature26155. doi: 10.1038/nature26155. PubMed Journal

Articles Citing xCas9 3.7

Articles
Directed evolution of CRISPR-Cas9 to increase its specificity. Lee JK, Jeong E, Lee J, Jung M, Shin E, Kim YH, Lee K, Jung I, Kim D, Kim S, Kim JS. Nat Commun. 2018 Aug 6;9(1):3048. doi: 10.1038/s41467-018-05477-x. PubMed

Associated Plasmids
Creation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing. Haldeman JM, Conway AE, Arlotto ME, Slentz DH, Muoio DM, Becker TC, Newgard CB. Nucleic Acids Res. 2018 Dec 27. pii: 5264291. doi: 10.1093/nar/gky1286. PubMed

Associated Plasmids
Genome Editing in Mammalian Cell Lines using CRISPR-Cas. Liu KI, Sutrisnoh NB, Wang Y, Tan MH. J Vis Exp. 2019 Apr 11;(146). doi: 10.3791/59086. PubMed
Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction. Suzuki K, Yamamoto M, Hernandez-Benitez R, Li Z, Wei C, Soligalla RD, Aizawa E, Hatanaka F, Kurita M, Reddy P, Ocampo A, Hishida T, Sakurai M, Nemeth AN, Nunez Delicado E, Campistol JM, Magistretti P, Guillen P, Rodriguez Esteban C, Gong J, Yuan Y, Gu Y, Liu GH, Lopez-Otin C, Wu J, Zhang K, Izpisua Belmonte JC. Cell Res. 2019 Oct;29(10):804-819. doi: 10.1038/s41422-019-0213-0. Epub 2019 Aug 23. PubMed
dupe-Precise and broad scope genome editing based on high-specificity Cas9 nickases. Wang Q, Liu J, Janssen JM, Le Bouteiller M, Frock RL, Goncalves MAFV. Nucleic Acids Res. 2021 Jan 25;49(2):1173-1198. doi: 10.1093/nar/gkaa1236. PubMed
Quantitative assessment of engineered Cas9 variants for target specificity enhancement by single-molecule reaction pathway analysis. Bak SY, Jung Y, Park J, Sung K, Jang HK, Bae S, Kim SK. Nucleic Acids Res. 2021 Nov 8;49(19):11312-11322. doi: 10.1093/nar/gkab858. PubMed
Delete_Adenine Base Editing System for Pseudomonas and Prediction Workflow for Protein Dysfunction via ABE. Abdullah, Wang P, Han T, Liu W, Ren W, Wu Y, Xiao Y. ACS Synth Biol. 2022 Apr 15;11(4):1650-1657. doi: 10.1021/acssynbio.2c00066. Epub 2022 Apr 7. PubMed
RNA helicase-dependent gene looping impacts messenger RNA processing. Terrone S, Valat J, Fontrodona N, Giraud G, Claude JB, Combe E, Lapendry A, Polveche H, Ameur LB, Duvermy A, Modolo L, Bernard P, Mortreux F, Auboeuf D, Bourgeois CF. Nucleic Acids Res. 2022 Sep 9;50(16):9226-9246. doi: 10.1093/nar/gkac717. PubMed

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