myc-Rictor corrected Citations (31)

Originally described in: Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton.
Sarbassov DD, Ali SM, Kim DH, Guertin DA, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM Curr Biol 2004 Jul 27;14(14):1296-302. PubMed Journal

---

Articles Citing myc-Rictor corrected

Articles
A Rictor-Myo1c complex participates in dynamic cortical actin events in 3T3-L1 adipocytes. Hagan GN, Lin Y, Magnuson MA, Avruch J, Czech MP. Mol Cell Biol. 2008 Jul . 28(13):4215-26. PubMed
Rictor is a novel target of p70 S6 kinase-1. Treins C, Warne PH, Magnuson MA, Pende M, Downward J. Oncogene. 2009 Nov 23. ():. PubMed
Activation of Akt by the bacterial inositol phosphatase, SopB, is wortmannin insensitive. Cooper KG, Winfree S, Malik-Kale P, Jolly C, Ireland R, Knodler LA, Steele-Mortimer O. PLoS One. 2011;6(7):e22260. doi: 10.1371/journal.pone.0022260. Epub 2011 Jul 14. PubMed
An in vitro assay for the kinase activity of mTOR complex 2. Huang J. Methods Mol Biol. 2012;821:75-86. doi: 10.1007/978-1-61779-430-8_6. PubMed
Mammalian target of rapamycin complex 1 (mTORC1) and 2 (mTORC2) control the dendritic arbor morphology of hippocampal neurons. Urbanska M, Gozdz A, Swiech LJ, Jaworski J. J Biol Chem. 2012 Aug 31;287(36):30240-56. doi: 10.1074/jbc.M112.374405. Epub 2012 Jul 18. PubMed
Sestrin 3 protein enhances hepatic insulin sensitivity by direct activation of the mTORC2-Akt signaling. Tao R, Xiong X, Liangpunsakul S, Dong XC. Diabetes. 2015 Apr;64(4):1211-23. doi: 10.2337/db14-0539. Epub 2014 Nov 5. PubMed
Rictor Undergoes Glycogen Synthase Kinase 3 (GSK3)-dependent, FBXW7-mediated Ubiquitination and Proteasomal Degradation. Koo J, Wu X, Mao Z, Khuri FR, Sun SY. J Biol Chem. 2015 May 29;290(22):14120-9. doi: 10.1074/jbc.M114.633057. Epub 2015 Apr 20. PubMed
PI3K/mTORC2 regulates TGF-beta/Activin signalling by modulating Smad2/3 activity via linker phosphorylation. Yu JS, Ramasamy TS, Murphy N, Holt MK, Czapiewski R, Wei SK, Cui W. Nat Commun. 2015 May 22;6:7212. doi: 10.1038/ncomms8212. PubMed
Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition. Singh BK, Sinha RA, Zhou J, Tripathi M, Ohba K, Wang ME, Astapova I, Ghosh S, Hollenberg AN, Gauthier K, Yen PM. J Biol Chem. 2016 Jan 1;291(1):198-214. doi: 10.1074/jbc.M115.668673. Epub 2015 Oct 9. PubMed
The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Carbonneau M, M Gagne L, Lalonde ME, Germain MA, Motorina A, Guiot MC, Secco B, Vincent EE, Tumber A, Hulea L, Bergeman J, Oppermann U, Jones RG, Laplante M, Topisirovic I, Petrecca K, Huot ME, Mallette FA. Nat Commun. 2016 Sep 14;7:12700. doi: 10.1038/ncomms12700. PubMed
Lycopene Protects Keratinocytes Against UVB Radiation-Induced Carcinogenesis via Negative Regulation of FOXO3a Through the mTORC2/AKT Signaling Pathway. Chen P, Xu S, Qu J. J Cell Biochem. 2017 Jun 6. doi: 10.1002/jcb.26189. PubMed
mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT. Gu Y, Albuquerque CP, Braas D, Zhang W, Villa GR, Bi J, Ikegami S, Masui K, Gini B, Yang H, Gahman TC, Shiau AK, Cloughesy TF, Christofk HR, Zhou H, Guan KL, Mischel PS. Mol Cell. 2017 Jul 6;67(1):128-138.e7. doi: 10.1016/j.molcel.2017.05.030. Epub 2017 Jun 22. PubMed
A Positive Feedback Loop between Sestrin2 and mTORC2 Is Required for the Survival of Glutamine-Depleted Lung Cancer Cells. Byun JK, Choi YK, Kim JH, Jeong JY, Jeon HJ, Kim MK, Hwang I, Lee SY, Lee YM, Lee IK, Park KG. Cell Rep. 2017 Jul 18;20(3):586-599. doi: 10.1016/j.celrep.2017.06.066. PubMed
Architecture of the human mTORC2 core complex. Stuttfeld E, Aylett CH, Imseng S, Boehringer D, Scaiola A, Sauer E, Hall MN, Maier T, Ban N. Elife. 2018 Feb 9;7. pii: 33101. doi: 10.7554/eLife.33101. PubMed
Increased Levels of Rictor Prevent Mutant Huntingtin-Induced Neuronal Degeneration. Creus-Muncunill J, Rue L, Alcala-Vida R, Badillos-Rodriguez R, Romani-Aumedes J, Marco S, Alberch J, Perez-Otano I, Malagelada C, Perez-Navarro E. Mol Neurobiol. 2018 Oct;55(10):7728-7742. doi: 10.1007/s12035-018-0956-5. Epub 2018 Feb 19. PubMed
MITF-MIR211 axis is a novel autophagy amplifier system during cellular stress. Ozturk DG, Kocak M, Akcay A, Kinoglu K, Kara E, Buyuk Y, Kazan H, Gozuacik D. Autophagy. 2019 Mar;15(3):375-390. doi: 10.1080/15548627.2018.1531197. Epub 2018 Oct 16. PubMed
Loss of GCN5L1 in cardiac cells disrupts glucose metabolism and promotes cell death via reduced Akt/mTORC2 signaling. Manning JR, Thapa D, Zhang M, Stoner MW, Traba J, Corey C, Shiva S, Sack MN, Scott I. Biochem J. 2019 Jun 19;476(12):1713-1724. doi: 10.1042/BCJ20190302. PubMed
Disruption of the RICTOR/mTORC2 complex enhances the response of head and neck squamous cell carcinoma cells to PI3K inhibition. Ruicci KM, Plantinga P, Pinto N, Khan MI, Stecho W, Dhaliwal SS, Yoo J, Fung K, MacNeil D, Mymryk JS, Barrett JW, Howlett CJ, Nichols AC. Mol Oncol. 2019 Oct;13(10):2160-2177. doi: 10.1002/1878-0261.12558. Epub 2019 Aug 28. PubMed
Two conserved glycine residues in mammalian and Dictyostelium Rictor are required for mTORC2 activity and integrity. Pergolizzi B, Panuzzo C, Ali MS, Lo Iacono M, Levra Levron C, Ponzone L, Prelli M, Cilloni D, Calautti E, Bozzaro S, Bracco E. J Cell Sci. 2019 Nov 14;132(22). pii: jcs.236505. doi: 10.1242/jcs.236505. PubMed
CD146 Regulates Growth Factor-Induced mTORC2 Activity Independent of the PI3K and mTORC1 Pathways. Xu W, Hua H, Chiu YH, Li G, Zhi H, Yu Z, Ren F, Luo Y, Cui W. Cell Rep. 2019 Oct 29;29(5):1311-1322.e5. doi: 10.1016/j.celrep.2019.09.047. PubMed
Desialylation of Sonic-Hedgehog by Neu2 Inhibits Its Association with Patched1 Reducing Stemness-Like Properties in Pancreatic Cancer Sphere-forming Cells. Nath S, Mondal S, Butti R, Prasanna Gunasekaran V, Chatterjee U, Halder A, Kundu GC, Mandal C. Cells. 2020 Jun 21;9(6). pii: cells9061512. doi: 10.3390/cells9061512. PubMed
TMBIM6/BI-1 contributes to cancer progression through assembly with mTORC2 and AKT activation. Kim HK, Bhattarai KR, Junjappa RP, Ahn JH, Pagire SH, Yoo HJ, Han J, Lee D, Kim KW, Kim HR, Chae HJ. Nat Commun. 2020 Aug 11;11(1):4012. doi: 10.1038/s41467-020-17802-4. PubMed
mTOR modulates resistance to gemcitabine in lung cancer in an MTORC2 dependent mechanism. Chawsheen MA, Dash PR. Cell Signal. 2021 May;81:109934. doi: 10.1016/j.cellsig.2021.109934. Epub 2021 Feb 3. PubMed
Rictor, an essential component of mTOR complex 2, undergoes caspase-mediated cleavage during apoptosis induced by multiple stimuli. Zhao L, Zhu L, Oh YT, Qian G, Chen Z, Sun SY. Apoptosis. 2021 Jun;26(5-6):338-347. doi: 10.1007/s10495-021-01676-y. Epub 2021 Apr 27. PubMed
Integrated analysis of Shank1 PDZ interactions with C-terminal and internal binding motifs. Ali M, McAuley MM, Luchow S, Knapp S, Joerger AC, Ivarsson Y. Curr Res Struct Biol. 2021 Jan 5;3:41-50. doi: 10.1016/j.crstbi.2021.01.001. eCollection 2021. PubMed
mTOR Inhibition Promotes Pneumonitis Through Inducing Endothelial Contraction and Hyperpermeability. Chen X, Hu C, Fan X, Wang Y, Li Q, Su YQ, Zhang DM, Yang Q, Passerini AG, Sun C. Am J Respir Cell Mol Biol. 2021 Jul 12. doi: 10.1165/rcmb.2020-0390OC. PubMed
Selective obstruction of the mTORC2 complex by a naturally occurring cholestane saponin (OSW-1) for inhibiting prostate cancer cell growth. Elgehama A. J Asian Nat Prod Res. 2021 Jul 22:1-10. doi: 10.1080/10286020.2021.1951255. PubMed
Novel role of the synaptic scaffold protein Dlgap4 in ventricular surface integrity and neuronal migration during cortical development. Romero DM, Poirier K, Belvindrah R, Moutkine I, Houllier A, LeMoing AG, Petit F, Boland A, Collins SC, Soiza-Reilly M, Yalcin B, Chelly J, Deleuze JF, Bahi-Buisson N, Francis F. Nat Commun. 2022 May 18;13(1):2746. doi: 10.1038/s41467-022-30443-z. PubMed
Interactions between mTORC2 core subunits Rictor and mSin1 dictate selective and context-dependent phosphorylation of substrate kinases SGK1 and Akt. Yu Z, Chen J, Takagi E, Wang F, Saha B, Liu X, Joubert LM, Gleason CE, Jin M, Li C, Nowotny C, Agard D, Cheng Y, Pearce D. J Biol Chem. 2022 Sep;298(9):102288. doi: 10.1016/j.jbc.2022.102288. Epub 2022 Aug 1. PubMed
Phosphoproteomic Analysis Defines BABAM1 as mTORC2 Downstream Effector Promoting DNA Damage Response in Glioblastoma Cells. Kalpongnukul N, Bootsri R, Wongkongkathep P, Kaewsapsak P, Ariyachet C, Pisitkun T, Chantaravisoot N. J Proteome Res. 2022 Dec 2;21(12):2893-2904. doi: 10.1021/acs.jproteome.2c00240. Epub 2022 Oct 31. PubMed
miR-192 inhibits the activation of hepatic stellate cells by targeting Rictor. Kang H, Luo J, Wang C, Hong Y, Ye M, Ding Y, Zhao Q, Chang Y. Open Med (Wars). 2023 Dec 26;18(1):20230879. doi: 10.1515/med-2023-0879. eCollection 2023. PubMed

If you have published an article using this material, please email us at to have your article added to this page.