EGFP-LC3 Citations (168)

Originally described in: Subversion of cellular autophagosomal machinery by RNA viruses.
Jackson WT, Giddings TH, Taylor MP, Mulinyawe S, Rabinovitch M, Kopito RR, Kirkegaard K PLoS Biol. 2005 May . 3(5):e156. PubMed Journal

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Articles Citing EGFP-LC3

Articles
TBK1 protects vacuolar integrity during intracellular bacterial infection. Radtke AL, Delbridge LM, Balachandran S, Barber GN, O'Riordan MX. PLoS Pathog. 2007 Mar;3(3):e29. PubMed
Oxidized low-density lipoproteins upregulate proline oxidase to initiate ROS-dependent autophagy. Zabirnyk O, Liu W, Khalil S, Sharma A, Phang JM. Carcinogenesis. 2010 Mar;31(3):446-54. doi: 10.1093/carcin/bgp299. Epub 2009 Nov 25. PubMed
Critical roles for mTORC2- and rapamycin-insensitive mTORC1-complexes in growth and survival of BCR-ABL-expressing leukemic cells. Carayol N, Vakana E, Sassano A, Kaur S, Goussetis DJ, Glaser H, Druker BJ, Donato NJ, Altman JK, Barr S, Platanias LC. Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12469-74. doi: 10.1073/pnas.1005114107. Epub 2010 Jun 28. PubMed
Autophagy is a critical mechanism for the induction of the antileukemic effects of arsenic trioxide. Goussetis DJ, Altman JK, Glaser H, McNeer JL, Tallman MS, Platanias LC. J Biol Chem. 2010 Sep 24;285(39):29989-97. doi: 10.1074/jbc.M109.090530. Epub 2010 Jul 23. PubMed
Fragmentation of the Golgi apparatus provides replication membranes for human rhinovirus 1A. Quiner CA, Jackson WT. Virology. 2010 Nov 25;407(2):185-95. doi: 10.1016/j.virol.2010.08.012. Epub 2010 Sep 9. PubMed
Alix regulates egress of hepatitis B virus naked capsid particles in an ESCRT-independent manner. Bardens A, Doring T, Stieler J, Prange R. Cell Microbiol. 2011 Apr;13(4):602-19. doi: 10.1111/j.1462-5822.2010.01557.x. Epub 2010 Dec 28. PubMed
Mutant A53T alpha-synuclein induces neuronal death by increasing mitochondrial autophagy. Choubey V, Safiulina D, Vaarmann A, Cagalinec M, Wareski P, Kuum M, Zharkovsky A, Kaasik A. J Biol Chem. 2011 Mar 25;286(12):10814-24. doi: 10.1074/jbc.M110.132514. Epub 2011 Jan 20. PubMed
Pancreatic cancers require autophagy for tumor growth. Yang S, Wang X, Contino G, Liesa M, Sahin E, Ying H, Bause A, Li Y, Stommel JM, Dell'antonio G, Mautner J, Tonon G, Haigis M, Shirihai OS, Doglioni C, Bardeesy N, Kimmelman AC. Genes Dev. 2011 Apr 1;25(7):717-29. doi: 10.1101/gad.2016111. Epub 2011 Mar 15. PubMed
Presenilin is necessary for efficient proteolysis through the autophagy-lysosome system in a gamma-secretase-independent manner. Neely KM, Green KN, LaFerla FM. J Neurosci. 2011 Feb 23;31(8):2781-91. doi: 10.1523/JNEUROSCI.5156-10.2010. PubMed
Role of autophagy in angiogenesis in aortic endothelial cells. Du J, Teng RJ, Guan T, Eis A, Kaul S, Konduri GG, Shi Y. Am J Physiol Cell Physiol. 2012 Jan 15;302(2):C383-91. doi: 10.1152/ajpcell.00164.2011. Epub 2011 Oct 26. PubMed
PARK9-associated ATP13A2 localizes to intracellular acidic vesicles and regulates cation homeostasis and neuronal integrity. Ramonet D, Podhajska A, Stafa K, Sonnay S, Trancikova A, Tsika E, Pletnikova O, Troncoso JC, Glauser L, Moore DJ. Hum Mol Genet. 2012 Apr 15;21(8):1725-43. doi: 10.1093/hmg/ddr606. Epub 2011 Dec 20. PubMed
Kras(G12D) and p53 mutation cause primary intrahepatic cholangiocarcinoma. O'Dell MR, Huang JL, Whitney-Miller CL, Deshpande V, Rothberg P, Grose V, Rossi RM, Zhu AX, Land H, Bardeesy N, Hezel AF. Cancer Res. 2012 Mar 15;72(6):1557-67. doi: 10.1158/0008-5472.CAN-11-3596. Epub 2012 Jan 20. PubMed
Mcl-1 determines the imiquimod-induced apoptosis but not imiquimod-induced autophagy in skin cancer cells. Huang SW, Chang CC, Lin CC, Tsai JJ, Chen YJ, Wu CY, Liu KT, Shieh JJ. J Dermatol Sci. 2012 Mar;65(3):170-8. doi: 10.1016/j.jdermsci.2011.11.001. Epub 2011 Nov 16. PubMed
Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy. Scheibye-Knudsen M, Ramamoorthy M, Sykora P, Maynard S, Lin PC, Minor RK, Wilson DM 3rd, Cooper M, Spencer R, de Cabo R, Croteau DL, Bohr VA. J Exp Med. 2012 Apr 9;209(4):855-69. doi: 10.1084/jem.20111721. Epub 2012 Apr 2. PubMed
A knockout of the Tsg101 gene leads to decreased expression of ErbB receptor tyrosine kinases and induction of autophagy prior to cell death. Morris CR, Stanton MJ, Manthey KC, Oh KB, Wagner KU. PLoS One. 2012;7(3):e34308. doi: 10.1371/journal.pone.0034308. Epub 2012 Mar 30. PubMed
Identification of novel human damage response proteins targeted through yeast orthology. Svensson JP, Fry RC, Wang E, Somoza LA, Samson LD. PLoS One. 2012;7(5):e37368. doi: 10.1371/journal.pone.0037368. Epub 2012 May 16. PubMed
Glutaminolysis activates Rag-mTORC1 signaling. Duran RV, Oppliger W, Robitaille AM, Heiserich L, Skendaj R, Gottlieb E, Hall MN. Mol Cell. 2012 Aug 10;47(3):349-58. doi: 10.1016/j.molcel.2012.05.043. Epub 2012 Jun 29. PubMed
Dysregulation of autophagy in murine fibroblasts resistant to HSV-1 infection. Le Sage V, Banfield BW. PLoS One. 2012;7(8):e42636. doi: 10.1371/journal.pone.0042636. Epub 2012 Aug 10. PubMed
Impaired autophagy leads to abnormal dendritic cell-epithelial cell interactions. Strisciuglio C, Duijvestein M, Verhaar AP, Vos AC, van den Brink GR, Hommes DW, Wildenberg ME. J Crohns Colitis. 2013 Aug;7(7):534-41. doi: 10.1016/j.crohns.2012.08.009. Epub 2012 Sep 13. PubMed
Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome. Tumbarello DA, Waxse BJ, Arden SD, Bright NA, Kendrick-Jones J, Buss F. Nat Cell Biol. 2012 Oct;14(10):1024-35. doi: 10.1038/ncb2589. Epub 2012 Sep 30. PubMed
Aurora kinase A inhibition-induced autophagy triggers drug resistance in breast cancer cells. Zou Z, Yuan Z, Zhang Q, Long Z, Chen J, Tang Z, Zhu Y, Chen S, Xu J, Yan M, Wang J, Liu Q. Autophagy. 2012 Dec;8(12):1798-810. doi: 10.4161/auto.22110. Epub 2012 Oct 1. PubMed
The ubiquitin ligase Mul1 induces mitophagy in skeletal muscle in response to muscle-wasting stimuli. Lokireddy S, Wijesoma IW, Teng S, Bonala S, Gluckman PD, McFarlane C, Sharma M, Kambadur R. Cell Metab. 2012 Nov 7;16(5):613-24. doi: 10.1016/j.cmet.2012.10.005. PubMed
p53 modulates the AMPK inhibitor compound C induced apoptosis in human skin cancer cells. Huang SW, Wu CY, Wang YT, Kao JK, Lin CC, Chang CC, Mu SW, Chen YY, Chiu HW, Chang CH, Liang SM, Chen YJ, Huang JL, Shieh JJ. Toxicol Appl Pharmacol. 2013 Feb 15;267(1):113-24. doi: 10.1016/j.taap.2012.12.016. Epub 2012 Dec 27. PubMed
Human papillomavirus infection is inhibited by host autophagy in primary human keratinocytes. Griffin LM, Cicchini L, Pyeon D. Virology. 2013 Mar 1;437(1):12-9. doi: 10.1016/j.virol.2012.12.004. Epub 2013 Jan 4. PubMed
Heat shock factor 1 (HSF1) controls chemoresistance and autophagy through transcriptional regulation of autophagy-related protein 7 (ATG7). Desai S, Liu Z, Yao J, Patel N, Chen J, Wu Y, Ahn EE, Fodstad O, Tan M. J Biol Chem. 2013 Mar 29;288(13):9165-76. doi: 10.1074/jbc.M112.422071. Epub 2013 Feb 5. PubMed
Mesenchymal bone marrow stem cells within polyglycolic acid tube observed in vivo after six weeks enhance facial nerve regeneration. Costa HJ, Ferreira Bento R, Salomone R, Azzi-Nogueira D, Zanatta DB, Paulino Costa M, da Silva CF, Strauss BE, Haddad LA. Brain Res. 2013 May 13;1510:10-21. doi: 10.1016/j.brainres.2013.03.025. Epub 2013 Mar 28. PubMed
Streptolysin O and its co-toxin NAD-glycohydrolase protect group A Streptococcus from Xenophagic killing. O'Seaghdha M, Wessels MR. PLoS Pathog. 2013;9(6):e1003394. doi: 10.1371/journal.ppat.1003394. Epub 2013 Jun 6. PubMed
Spatiotemporally controlled induction of autophagy-mediated lysosome turnover. Hung YH, Chen LM, Yang JY, Yang WY. Nat Commun. 2013;4:2111. doi: 10.1038/ncomms3111. PubMed
Bit-by-bit autophagic removal of parkin-labelled mitochondria. Yang JY, Yang WY. Nat Commun. 2013;4:2428. doi: 10.1038/ncomms3428. PubMed
Describing autophagy via analysis of individual organelles by capillary electrophoresis with laser induced fluorescence detection. Satori CP, Arriaga EA. Anal Chem. 2013 Dec 3;85(23):11391-400. doi: 10.1021/ac4023549. Epub 2013 Nov 14. PubMed
Autophagy mediates avian influenza H5N1 pseudotyped particle-induced lung inflammation through NF-kappaB and p38 MAPK signaling pathways. Pan H, Zhang Y, Luo Z, Li P, Liu L, Wang C, Wang H, Li H, Ma Y. Am J Physiol Lung Cell Mol Physiol. 2014 Jan;306(2):L183-95. doi: 10.1152/ajplung.00147.2013. Epub 2013 Nov 15. PubMed
Resveratrol induced ER expansion and ER caspase-mediated apoptosis in human nasopharyngeal carcinoma cells. Chow SE, Kao CH, Liu YT, Cheng ML, Yang YW, Huang YK, Hsu CC, Wang JS. Apoptosis. 2014 Mar;19(3):527-41. doi: 10.1007/s10495-013-0945-0. PubMed
In vitro and in vivo antitumor effects of Peanut agglutinin through induction of apoptotic and autophagic cell death. Mukhopadhyay S, Panda PK, Behera B, Das CK, Hassan MK, Das DN, Sinha N, Bissoyi A, Pramanik K, Maiti TK, Bhutia SK. Food Chem Toxicol. 2014 Feb;64:369-77. doi: 10.1016/j.fct.2013.11.046. Epub 2013 Dec 9. PubMed
The Vac14-interaction network is linked to regulators of the endolysosomal and autophagic pathway. Schulze U, Vollenbroker B, Braun DA, Van Le T, Granado D, Kremerskothen J, Franzel B, Klosowski R, Barth J, Fufezan C, Wolters DA, Pavenstadt H, Weide T. Mol Cell Proteomics. 2014 Jun;13(6):1397-411. doi: 10.1074/mcp.M113.034108. Epub 2014 Feb 27. PubMed
Role of autophagy in high linear energy transfer radiation-induced cytotoxicity to tumor cells. Jin X, Liu Y, Ye F, Liu X, Furusawa Y, Wu Q, Li F, Zheng X, Dai Z, Li Q. Cancer Sci. 2014 Jul;105(7):770-8. doi: 10.1111/cas.12422. Epub 2014 May 24. PubMed
Targeting SQSTM1/p62 induces cargo loading failure and converts autophagy to apoptosis via NBK/Bik. Chen S, Zhou L, Zhang Y, Leng Y, Pei XY, Lin H, Jones R, Orlowski RZ, Dai Y, Grant S. Mol Cell Biol. 2014 Sep 15;34(18):3435-49. doi: 10.1128/MCB.01383-13. Epub 2014 Jul 7. PubMed
Endoplasmic reticulum vacuolation and unfolded protein response leading to paraptosis like cell death in cyclosporine A treated cancer cervix cells is mediated by cyclophilin B inhibition. Ram BM, Ramakrishna G. Biochim Biophys Acta. 2014 Nov;1843(11):2497-512. doi: 10.1016/j.bbamcr.2014.06.020. Epub 2014 Jul 5. PubMed
Antitumor effect of soybean lectin mediated through reactive oxygen species-dependent pathway. Panda PK, Mukhopadhyay S, Behera B, Bhol CS, Dey S, Das DN, Sinha N, Bissoyi A, Pramanik K, Maiti TK, Bhutia SK. Life Sci. 2014 Aug 28;111(1-2):27-35. doi: 10.1016/j.lfs.2014.07.004. Epub 2014 Jul 23. PubMed
A Bim-targeting strategy overcomes adaptive bortezomib resistance in myeloma through a novel link between autophagy and apoptosis. Chen S, Zhang Y, Zhou L, Leng Y, Lin H, Kmieciak M, Pei XY, Jones R, Orlowski RZ, Dai Y, Grant S. Blood. 2014 Oct 23;124(17):2687-97. doi: 10.1182/blood-2014-03-564534. Epub 2014 Sep 10. PubMed
YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells. Cheng SM, Chang YC, Liu CY, Lee JY, Chan HH, Kuo CW, Lin KY, Tsai SL, Chen SH, Li CF, Leung E, Kanwar JR, Huang CC, Chang JY, Cheung CH. Br J Pharmacol. 2015 Jan;172(1):214-34. doi: 10.1111/bph.12935. Epub 2014 Dec 1. PubMed
Molecular mechanisms of fenofibrate-induced metabolic catastrophe and glioblastoma cell death. Wilk A, Wyczechowska D, Zapata A, Dean M, Mullinax J, Marrero L, Parsons C, Peruzzi F, Culicchia F, Ochoa A, Grabacka M, Reiss K. Mol Cell Biol. 2015 Jan;35(1):182-98. doi: 10.1128/MCB.00562-14. Epub 2014 Oct 20. PubMed
Immunotherapy targeting folate receptor induces cell death associated with autophagy in ovarian cancer. Wen Y, Graybill WS, Previs RA, Hu W, Ivan C, Mangala LS, Zand B, Nick AM, Jennings NB, Dalton HJ, Sehgal V, Ram P, Lee JS, Vivas-Mejia PE, Coleman RL, Sood AK. Clin Cancer Res. 2015 Jan 15;21(2):448-59. doi: 10.1158/1078-0432.CCR-14-1578. Epub 2014 Nov 21. PubMed
Iron alters cell survival in a mitochondria-dependent pathway in ovarian cancer cells. Bauckman K, Haller E, Taran N, Rockfield S, Ruiz-Rivera A, Nanjundan M. Biochem J. 2015 Mar 1;466(2):401-13. doi: 10.1042/BJ20140878. PubMed
Targeting Hedgehog signaling pathway and autophagy overcomes drug resistance of BCR-ABL-positive chronic myeloid leukemia. Zeng X, Zhao H, Li Y, Fan J, Sun Y, Wang S, Wang Z, Song P, Ju D. Autophagy. 2015;11(2):355-72. doi: 10.4161/15548627.2014.994368. PubMed
A rapid and high content assay that measures cyto-ID-stained autophagic compartments and estimates autophagy flux with potential clinical applications. Guo S, Liang Y, Murphy SF, Huang A, Shen H, Kelly DF, Sobrado P, Sheng Z. Autophagy. 2015;11(3):560-72. doi: 10.1080/15548627.2015.1017181. PubMed
Imiquimod-induced AMPK activation causes translation attenuation and apoptosis but not autophagy. Wang ST, Huang SW, Kao JK, Liang SM, Chen YJ, Chen YY, Wu CY, Shieh JJ. J Dermatol Sci. 2015 May;78(2):108-16. doi: 10.1016/j.jdermsci.2015.02.008. Epub 2015 Feb 23. PubMed
Impaired autophagy in mouse embryonic fibroblasts null for Kruppel-like Factor 4 promotes DNA damage and increases apoptosis upon serum starvation. Liu C, DeRoo EP, Stecyk C, Wolsey M, Szuchnicki M, Hagos EG. Mol Cancer. 2015 May 6;14:101. doi: 10.1186/s12943-015-0373-6. PubMed
Altered lysosomal positioning affects lysosomal functions in a cellular model of Huntington's disease. Erie C, Sacino M, Houle L, Lu ML, Wei J. Eur J Neurosci. 2015 May 22. doi: 10.1111/ejn.12957. PubMed
Impacts of autophagy-inducing ingredient of areca nut on tumor cells. Yen CY, Chiang WF, Liu SY, Lin CC, Liao KA, Lin CY, Hsieh WF, Cheng YC, Hsu KC, Lin PY, Chen TC, Lee IL, Lin MH, Liu YC. PLoS One. 2015 May 27;10(5):e0128011. doi: 10.1371/journal.pone.0128011. eCollection 2015. PubMed
alpha-Solanine induces ROS-mediated autophagy through activation of endoplasmic reticulum stress and inhibition of Akt/mTOR pathway. Hasanain M, Bhattacharjee A, Pandey P, Ashraf R, Singh N, Sharma S, Vishwakarma AL, Datta D, Mitra K, Sarkar J. Cell Death Dis. 2015 Aug 27;6:e1860. doi: 10.1038/cddis.2015.219. PubMed
Autophagy Contributes to the Induction of Anti-TNF Induced Macrophages. Levin AD, Koelink PJ, Bloemendaal FM, Vos AC, D'Haens GR, van den Brink GR, Wildenberg ME. J Crohns Colitis. 2015 Sep 27. pii: jjv174. PubMed
EGCG antagonizes Bortezomib cytotoxicity in prostate cancer cells by an autophagic mechanism. Modernelli A, Naponelli V, Giovanna Troglio M, Bonacini M, Ramazzina I, Bettuzzi S, Rizzi F. Sci Rep. 2015 Oct 16;5:15270. doi: 10.1038/srep15270. PubMed
CGK733-induced LC3 II formation is positively associated with the expression of cyclin-dependent kinase inhibitor p21Waf1/Cip1 through modulation of the AMPK and PERK/CHOP signaling pathways. Wang Y, Kuramitsu Y, Baron B, Kitagawa T, Tokuda K, Akada J, Nakamura K. Oncotarget. 2015 Nov 24;6(37):39692-701. doi: 10.18632/oncotarget.5625. PubMed
TSG101 Silencing Suppresses Hepatocellular Carcinoma Cell Growth by Inducing Cell Cycle Arrest and Autophagic Cell Death. Shao Z, Ji W, Liu A, Qin A, Shen L, Li G, Zhou Y, Hu X, Yu E, Jin G. Med Sci Monit. 2015 Nov 5;21:3371-9. PubMed
Ferritinophagy drives uropathogenic Escherichia coli persistence in bladder epithelial cells. Bauckman KA, Mysorekar IU. Autophagy. 2016 May 3;12(5):850-63. doi: 10.1080/15548627.2016.1160176. PubMed
Inhibition of BMI1 induces autophagy-mediated necroptosis. Dey A, Mustafi SB, Saha S, Kumar Dhar Dwivedi S, Mukherjee P, Bhattacharya R. Autophagy. 2016 Apr 2;12(4):659-70. doi: 10.1080/15548627.2016.1147670. PubMed
Mitophagy acts as a safeguard mechanism against human vascular smooth muscle cell apoptosis induced by atherogenic lipids. Swiader A, Nahapetyan H, Faccini J, D'Angelo R, Mucher E, Elbaz M, Boya P, Vindis C. Oncotarget. 2016 May 17;7(20):28821-35. doi: 10.18632/oncotarget.8936. PubMed
Abrus agglutinin, a type II ribosome inactivating protein inhibits Akt/PH domain to induce endoplasmic reticulum stress mediated autophagy-dependent cell death. Panda PK, Behera B, Meher BR, Das DN, Mukhopadhyay S, Sinha N, Naik PP, Roy B, Das J, Paul S, Maiti TK, Agarwal R, Bhutia SK. Mol Carcinog. 2016 May 16. doi: 10.1002/mc.22502. PubMed
TRIM31 promotes Atg5/Atg7-independent autophagy in intestinal cells. Ra EA, Lee TA, Won Kim S, Park A, Choi HJ, Jang I, Kang S, Hee Cheon J, Cho JW, Eun Lee J, Lee S, Park B. Nat Commun. 2016 May 24;7:11726. doi: 10.1038/ncomms11726. PubMed
Delivery of a survivin promoter-driven antisense survivin-expressing plasmid DNA as a cancer therapeutic: a proof-of-concept study. Lin KY, Cheng SM, Tsai SL, Tsai JY, Lin CH, Cheung CH. Onco Targets Ther. 2016 May 3;9:2601-13. doi: 10.2147/OTT.S101209. eCollection 2016. PubMed
Bacopa monnieri-Induced Protective Autophagy Inhibits Benzo[a]pyrene-Mediated Apoptosis. Das DN, Naik PP, Nayak A, Panda PK, Mukhopadhyay S, Sinha N, Bhutia SK. Phytother Res. 2016 Nov;30(11):1794-1801. doi: 10.1002/ptr.5682. Epub 2016 Jul 19. PubMed
TSC2 N-terminal lysine acetylation status affects to its stability modulating mTORC1 signaling and autophagy. Garcia-Aguilar A, Guillen C, Nellist M, Bartolome A, Benito M. Biochim Biophys Acta. 2016 Nov;1863(11):2658-2667. doi: 10.1016/j.bbamcr.2016.08.006. Epub 2016 Aug 16. PubMed
Telomerase reverse transcriptase induces basal and amino acid starvation-induced autophagy through mTORC1. Ali M, Devkota S, Roh JI, Lee J, Lee HW. Biochem Biophys Res Commun. 2016 Sep 23;478(3):1198-204. doi: 10.1016/j.bbrc.2016.08.094. Epub 2016 Aug 18. PubMed
PRNP/prion protein regulates the secretion of exosomes modulating CAV1/caveolin-1-suppressed autophagy. Dias MV, Teixeira BL, Rodrigues BR, Sinigaglia-Coimbra R, Porto-Carreiro I, Roffe M, Hajj GN, Martins VR. Autophagy. 2016 Nov;12(11):2113-2128. Epub 2016 Sep 14. PubMed
Antiviral activities of selected antimalarials against dengue virus type 2 and Zika virus. Balasubramanian A, Teramoto T, Kulkarni AA, Bhattacharjee AK, Padmanabhan R. Antiviral Res. 2017 Jan;137:141-150. doi: 10.1016/j.antiviral.2016.11.015. Epub 2016 Nov 23. PubMed
Subcellular localization of FOXO3a as a potential biomarker of response to combined treatment with inhibitors of PI3K and autophagy in PIK3CA-mutant cancer cells. Kim HJ, Lee SY, Kim CY, Kim YH, Ju W, Kim SC. Oncotarget. 2017 Jan 24;8(4):6608-6622. doi: 10.18632/oncotarget.14245. PubMed
mTORC1 inhibition in cancer cells protects from glutaminolysis-mediated apoptosis during nutrient limitation. Villar VH, Nguyen TL, Delcroix V, Teres S, Bouchecareilh M, Salin B, Bodineau C, Vacher P, Priault M, Soubeyran P, Duran RV. Nat Commun. 2017 Jan 23;8:14124. doi: 10.1038/ncomms14124. PubMed
CQ synergistically sensitizes human colorectal cancer cells to SN-38/CPT-11 through lysosomal and mitochondrial apoptotic pathway via p53-ROS cross-talk. Chen P, Luo X, Nie P, Wu B, Xu W, Shi X, Chang H, Li B, Yu X, Zou Z. Free Radic Biol Med. 2017 Mar;104:280-297. doi: 10.1016/j.freeradbiomed.2017.01.033. Epub 2017 Jan 25. PubMed
Glucagon-Like Peptide 1 Protects Pancreatic beta-Cells From Death by Increasing Autophagic Flux and Restoring Lysosomal Function. Zummo FP, Cullen KS, Honkanen-Scott M, Shaw JAM, Lovat PE, Arden C. Diabetes. 2017 May;66(5):1272-1285. doi: 10.2337/db16-1009. Epub 2017 Feb 23. PubMed
Cytoprotective effect of kaempferol against palmitic acid-induced pancreatic beta-cell death through modulation of autophagy via AMPK/mTOR signaling pathway. Varshney R, Gupta S, Roy P. Mol Cell Endocrinol. 2017 Jun 15;448:1-20. doi: 10.1016/j.mce.2017.02.033. Epub 2017 Feb 24. PubMed
Vitamin D receptor regulates autophagy in the normal mammary gland and in luminal breast cancer cells. Tavera-Mendoza LE, Westerling T, Libby E, Marusyk A, Cato L, Cassani R, Cameron LA, Ficarro SB, Marto JA, Klawitter J, Brown M. Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):E2186-E2194. doi: 10.1073/pnas.1615015114. Epub 2017 Feb 27. PubMed
Ischemia Induces Quiescence and Autophagy Dependence in Hepatocellular Carcinoma. Gade TPF, Tucker E, Nakazawa MS, Hunt SJ, Wong W, Krock B, Weber CN, Nadolski GJ, Clark TWI, Soulen MC, Furth EE, Winkler JD, Amaravadi RK, Simon MC. Radiology. 2017 Jun;283(3):702-710. doi: 10.1148/radiol.2017160728. Epub 2017 Mar 2. PubMed
High-Throughput Quantification of GFP-LC3(+) Dots by Automated Fluorescence Microscopy. Bravo-San Pedro JM, Pietrocola F, Sica V, Izzo V, Sauvat A, Kepp O, Maiuri MC, Kroemer G, Galluzzi L. Methods Enzymol. 2017;587:71-86. doi: 10.1016/bs.mie.2016.10.022. Epub 2016 Dec 29. PubMed
Activation of autophagy by elevated reactive oxygen species rather than released silver ions promotes cytotoxicity of polyvinylpyrrolidone-coated silver nanoparticles in hematopoietic cells. Zhu L, Guo D, Sun L, Huang Z, Zhang X, Ma W, Wu J, Xiao L, Zhao Y, Gu N. Nanoscale. 2017 May 4;9(17):5489-5498. doi: 10.1039/c6nr08188f. PubMed
Imiquimod-induced autophagy is regulated by ER stress-mediated PKR activation in cancer cells. Chang SH, Huang SW, Wang ST, Chung KC, Hsieh CW, Kao JK, Chen YJ, Wu CY, Shieh JJ. J Dermatol Sci. 2017 Aug;87(2):138-148. doi: 10.1016/j.jdermsci.2017.04.011. Epub 2017 May 2. PubMed
Protocols for assessing mitophagy in neuronal cell lines and primary neurons. Dagda RK, Rice M. Neuromethods. 2017;123:249-277. doi: 10.1007/978-1-4939-6890-9_13. Epub 2017 Mar 18. PubMed
Inhibition of autophagy limits vertical transmission of Zika virus in pregnant mice. Cao B, Parnell LA, Diamond MS, Mysorekar IU. J Exp Med. 2017 Aug 7;214(8):2303-2313. doi: 10.1084/jem.20170957. Epub 2017 Jul 10. PubMed
Phosphatidylinositol 4-phosphate 5-kinase alpha contributes to Toll-like receptor 2-mediated immune responses in microglial cells stimulated with lipoteichoic acid. Nguyen TTN, Seo E, Choi J, Le OTT, Kim JY, Jou I, Lee SY. Cell Signal. 2017 Oct;38:159-170. doi: 10.1016/j.cellsig.2017.07.009. Epub 2017 Jul 13. PubMed
Elimination of dysfunctional mitochondria through mitophagy suppresses benzo[a]pyrene-induced apoptosis. Das DN, Naik PP, Mukhopadhyay S, Panda PK, Sinha N, Meher BR, Bhutia SK. Free Radic Biol Med. 2017 Nov;112:452-463. doi: 10.1016/j.freeradbiomed.2017.08.020. Epub 2017 Aug 24. PubMed
VPS34 stimulation of p62 phosphorylation for cancer progression. Jiang X, Bao Y, Liu H, Kou X, Zhang Z, Sun F, Qian Z, Lin Z, Li X, Liu X, Jiang L, Yang Y. Oncogene. 2017 Dec 14;36(50):6850-6862. doi: 10.1038/onc.2017.295. Epub 2017 Aug 28. PubMed
The ER retention protein RER1 promotes alpha-synuclein degradation via the proteasome. Park HJ, Ryu D, Parmar M, Giasson BI, McFarland NR. PLoS One. 2017 Sep 6;12(9):e0184262. doi: 10.1371/journal.pone.0184262. eCollection 2017. PubMed
MTORC1 Regulates both General Autophagy and Mitophagy Induction after Oxidative Phosphorylation Uncoupling. Bartolome A, Garcia-Aguilar A, Asahara SI, Kido Y, Guillen C, Pajvani UB, Benito M. Mol Cell Biol. 2017 Sep 11. pii: MCB.00441-17. doi: 10.1128/MCB.00441-17. PubMed
PI3K-C2alpha knockdown decreases autophagy and maturation of endocytic vesicles. Merrill NM, Schipper JL, Karnes JB, Kauffman AL, Martin KR, MacKeigan JP. PLoS One. 2017 Sep 14;12(9):e0184909. doi: 10.1371/journal.pone.0184909. eCollection 2017. PubMed
Generation of an OCT4 reporter human induced pluripotent stem cell line using CRISPR/SpCas9. Balboa D, Weltner J, Novik Y, Eurola S, Wartiovaara K, Otonkoski T. Stem Cell Res. 2017 Aug;23:105-108. doi: 10.1016/j.scr.2017.07.006. Epub 2017 Jul 11. PubMed Associated Plasmids pUC19-OCT4-T2A-NLS-EmGFP-P2A-Puro CAG-Cas9
Ezetimibe ameliorates steatohepatitis via AMP activated protein kinase-TFEB-mediated activation of autophagy and NLRP3 inflammasome inhibition. Kim SH, Kim G, Han DH, Lee M, Kim I, Kim B, Kim KH, Song YM, Yoo JE, Wang HJ, Bae SH, Lee YH, Lee BW, Kang ES, Cha BS, Lee MS. Autophagy. 2017 Oct 3;13(10):1767-1781. doi: 10.1080/15548627.2017.1356977. Epub 2017 Sep 21. PubMed
Oncolytic Reovirus Infection Is Facilitated by the Autophagic Machinery. Kemp V, Dautzenberg IJC, Limpens RW, van den Wollenberg DJM, Hoeben RC. Viruses. 2017 Sep 21;9(10). pii: v9100266. doi: 10.3390/v9100266. PubMed
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