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pLL3.7 Citations (122)

Originally described in: A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference.
Rubinson DA, Dillon CP, Kwiatkowski AV, Sievers C, Yang L, Kopinja J, Rooney DL, Ihrig MM, McManus MT, Gertler FB, Scott ML, Van Parijs L Nat Genet. 2003 Mar . 33(3):401-6.
PubMed Journal

Articles Citing pLL3.7

Articles
Disc1 regulates granule cell migration in the developing hippocampus. Meyer KD, Morris JA. Hum Mol Genet. 2009 Sep 1;18(17):3286-97. doi: 10.1093/hmg/ddp266. Epub 2009 Jun 5. PubMed
Involvement of 4E-BP1 in the protection induced by HDLs on pancreatic beta-cells. Petremand J, Bulat N, Butty AC, Poussin C, Rutti S, Au K, Ghosh S, Mooser V, Thorens B, Yang JY, Widmann C, Waeber G. Mol Endocrinol. 2009 Oct;23(10):1572-86. doi: 10.1210/me.2008-0448. Epub 2009 Jul 2. PubMed
Tumor-initiating activity and tumor morphology of HNSCC is modulated by interactions between clonal variants within the tumor. Cameron SR, Dahler AL, Endo-Munoz LB, Jabbar I, Thomas GP, Leo PJ, Poth K, Rickwood D, Guminski A, Saunders NA. Lab Invest. 2010 Nov;90(11):1594-603. doi: 10.1038/labinvest.2010.131. Epub 2010 Jul 26. PubMed
Macrophage migration inhibitory factor counterregulates dexamethasone-mediated suppression of hypoxia-inducible factor-1 alpha function and differentially influences human CD4+ T cell proliferation under hypoxia. Gaber T, Schellmann S, Erekul KB, Fangradt M, Tykwinska K, Hahne M, Maschmeyer P, Wagegg M, Stahn C, Kolar P, Dziurla R, Lohning M, Burmester GR, Buttgereit F. J Immunol. 2011 Jan 15;186(2):764-74. doi: 10.4049/jimmunol.0903421. Epub 2010 Dec 17. PubMed
Visualization of virus-infected brain regions using a GFP-illuminating flashlight enables accurate and rapid dissection for biochemical analysis. Li X, Wolf ME. J Neurosci Methods. 2011 Sep 30;201(1):177-9. doi: 10.1016/j.jneumeth.2011.07.016. Epub 2011 Jul 23. PubMed
Origin and functional activity of the membrane-bound glucocorticoid receptor. Strehl C, Gaber T, Lowenberg M, Hommes DW, Verhaar AP, Schellmann S, Hahne M, Fangradt M, Wagegg M, Hoff P, Scheffold A, Spies CM, Burmester GR, Buttgereit F. Arthritis Rheum. 2011 Dec;63(12):3779-88. doi: 10.1002/art.30637. PubMed
Single-cell dissection of transcriptional heterogeneity in human colon tumors. Dalerba P, Kalisky T, Sahoo D, Rajendran PS, Rothenberg ME, Leyrat AA, Sim S, Okamoto J, Johnston DM, Qian D, Zabala M, Bueno J, Neff NF, Wang J, Shelton AA, Visser B, Hisamori S, Shimono Y, van de Wetering M, Clevers H, Clarke MF, Quake SR. Nat Biotechnol. 2011 Nov 13;29(12):1120-7. doi: 10.1038/nbt.2038. PubMed
Gene expression profiling of neural stem cells and their neuronal progeny reveals IGF2 as a regulator of adult hippocampal neurogenesis. Bracko O, Singer T, Aigner S, Knobloch M, Winner B, Ray J, Clemenson GD Jr, Suh H, Couillard-Despres S, Aigner L, Gage FH, Jessberger S. J Neurosci. 2012 Mar 7;32(10):3376-87. doi: 10.1523/JNEUROSCI.4248-11.2012. PubMed
Identification of microRNA-RNA interactions using tethered RNAs and streptavidin aptamers. Liu H, Zhang S, Lin H, Jia R, Chen Z. Biochem Biophys Res Commun. 2012 Jun 8;422(3):405-10. doi: 10.1016/j.bbrc.2012.05.002. Epub 2012 May 7. PubMed
Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex. de Anda FC, Rosario AL, Durak O, Tran T, Graff J, Meletis K, Rei D, Soda T, Madabhushi R, Ginty DD, Kolodkin AL, Tsai LH. Nat Neurosci. 2012 Jun 10;15(7):1022-31. doi: 10.1038/nn.3141. PubMed
Lentivirus-mediated short-hairpin RNA targeting IGF-1R inhibits growth and lymphangiogenesis in breast cancer. Chen Y, Zhu C, Peng Z, Dai Y, Gu Y. Oncol Rep. 2012 Nov;28(5):1778-84. doi: 10.3892/or.2012.1964. Epub 2012 Aug 10. PubMed
A unilateral negative feedback loop between miR-200 microRNAs and Sox2/E2F3 controls neural progenitor cell-cycle exit and differentiation. Peng C, Li N, Ng YK, Zhang J, Meier F, Theis FJ, Merkenschlager M, Chen W, Wurst W, Prakash N. J Neurosci. 2012 Sep 19;32(38):13292-308. PubMed
Hypoxia promotes osteogenesis but suppresses adipogenesis of human mesenchymal stromal cells in a hypoxia-inducible factor-1 dependent manner. Wagegg M, Gaber T, Lohanatha FL, Hahne M, Strehl C, Fangradt M, Tran CL, Schonbeck K, Hoff P, Ode A, Perka C, Duda GN, Buttgereit F. PLoS One. 2012;7(9):e46483. doi: 10.1371/journal.pone.0046483. Epub 2012 Sep 27. PubMed
Highly angiogenic CXCR4(+)CD31(+) monocyte subset derived from 3D culture of human peripheral blood. Hur J, Choi JI, Yun JY, Yoon CH, Jang JH, Im SG, Ko SB, Kang JA, Park J, Lee SE, Kim JY, Yang HM, Park YB, Kim HS. Biomaterials. 2013 Mar;34(8):1929-41. doi: 10.1016/j.biomaterials.2012.11.015. PubMed
miR-145 and miR-143 regulate odontoblast differentiation through targeting Klf4 and Osx genes in a feedback loop. Liu H, Lin H, Zhang L, Sun Q, Yuan G, Zhang L, Chen S, Chen Z. J Biol Chem. 2013 Mar 29;288(13):9261-71. doi: 10.1074/jbc.M112.433730. Epub 2013 Feb 19. PubMed
KLF4 promoted odontoblastic differentiation of mouse dental papilla cells via regulation of DMP1. Lin H, Liu H, Sun Q, Yuan G, Zhang L, Chen Z. J Cell Physiol. 2013 Oct;228(10):2076-85. doi: 10.1002/jcp.24377. PubMed
DISC1-ATF4 transcriptional repression complex: dual regulation of the cAMP-PDE4 cascade by DISC1. Soda T, Frank C, Ishizuka K, Baccarella A, Park YU, Flood Z, Park SK, Sawa A, Tsai LH. Mol Psychiatry. 2013 Aug;18(8):898-908. doi: 10.1038/mp.2013.38. Epub 2013 Apr 16. PubMed
The Pitx2:miR-200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation. Cao H, Jheon A, Li X, Sun Z, Wang J, Florez S, Zhang Z, McManus MT, Klein OD, Amendt BA. Development. 2013 Aug;140(16):3348-59. doi: 10.1242/dev.089193. Epub 2013 Jul 17. PubMed
DUX4 and DUX4 downstream target genes are expressed in fetal FSHD muscles. Ferreboeuf M, Mariot V, Bessieres B, Vasiljevic A, Attie-Bitach T, Collardeau S, Morere J, Roche S, Magdinier F, Robin-Ducellier J, Rameau P, Whalen S, Desnuelle C, Sacconi S, Mouly V, Butler-Browne G, Dumonceaux J. Hum Mol Genet. 2014 Jan 1;23(1):171-81. doi: 10.1093/hmg/ddt409. Epub 2013 Aug 20. PubMed
Genetic manipulation to analyze pheromone responses: knockouts of multiple receptor genes. Ishii T. Methods Mol Biol. 2013;1068:133-54. doi: 10.1007/978-1-62703-619-1_10. PubMed
MYPT1 regulates contractility and microtubule acetylation to modulate integrin adhesions and matrix assembly. Joo EE, Yamada KM. Nat Commun. 2014 Mar 25;5:3510. doi: 10.1038/ncomms4510. PubMed

Associated Plasmids

An extracellular-matrix-specific GEF-GAP interaction regulates Rho GTPase crosstalk for 3D collagen migration. Kutys ML, Yamada KM. Nat Cell Biol. 2014 Sep;16(9):909-17. doi: 10.1038/ncb3026. Epub 2014 Aug 24. PubMed
Genome-wide identification and characterization of functional neuronal activity-dependent enhancers. Malik AN, Vierbuchen T, Hemberg M, Rubin AA, Ling E, Couch CH, Stroud H, Spiegel I, Farh KK, Harmin DA, Greenberg ME. Nat Neurosci. 2014 Oct;17(10):1330-9. doi: 10.1038/nn.3808. Epub 2014 Sep 7. PubMed
Effective gene delivery into human stem cells with a cell-targeting Peptide-modified bioreducible polymer. Beloor J, Ramakrishna S, Nam K, Seon Choi C, Kim J, Kim SH, Cho HJ, Shin H, Kim H, Kim SW, Lee SK, Kumar P. Small. 2015 May;11(17):2069-79. doi: 10.1002/smll.201402933. Epub 2014 Dec 16. PubMed
In-vivo RGB marking and multicolour single-cell tracking in the adult brain. Gomez-Nicola D, Riecken K, Fehse B, Perry VH. Sci Rep. 2014 Dec 22;4:7520. doi: 10.1038/srep07520. PubMed
MicroRNA-22 regulates smooth muscle cell differentiation from stem cells by targeting methyl CpG-binding protein 2. Zhao H, Wen G, Huang Y, Yu X, Chen Q, Afzal TA, Luong le A, Zhu J, Ye S, Zhang L, Xiao Q. Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):918-29. doi: 10.1161/ATVBAHA.114.305212. Epub 2015 Feb 26. PubMed
Alternative methods for the efficient construction of short hairpin RNA expression vectors. Xu K, Zhang T, Guo L, Xin Y, Zhang L, Zhang Z. Anal Biochem. 2015 Jun 1;478:23-5. doi: 10.1016/j.ab.2015.03.006. Epub 2015 Mar 17. PubMed
E-Cadherin enhances neuregulin signaling and promotes Schwann cell myelination. Basak S, Desai DJ, Rho EH, Ramos R, Maurel P, Kim HA. Glia. 2015 Sep;63(9):1522-36. doi: 10.1002/glia.22822. Epub 2015 May 19. PubMed
IL-4 Regulates Specific Arg-1(+) Macrophage sFlt-1-Mediated Inhibition of Angiogenesis. Wu WK, Georgiadis A, Copland DA, Liyanage S, Luhmann UF, Robbie SJ, Liu J, Wu J, Bainbridge JW, Bates DO, Ali RR, Nicholson LB, Dick AD. Am J Pathol. 2015 Aug;185(8):2324-35. doi: 10.1016/j.ajpath.2015.04.013. Epub 2015 Jun 13. PubMed
A Combined Optogenetic-Knockdown Strategy Reveals a Major Role of Tomosyn in Mossy Fiber Synaptic Plasticity. Ben-Simon Y, Rodenas-Ruano A, Alvina K, Lam AD, Stuenkel EL, Castillo PE, Ashery U. Cell Rep. 2015 Jul 21;12(3):396-404. doi: 10.1016/j.celrep.2015.06.037. Epub 2015 Jul 9. PubMed
miR-205-5p-mediated downregulation of ErbB/HER receptors in breast cancer stem cells results in targeted therapy resistance. De Cola A, Volpe S, Budani MC, Ferracin M, Lattanzio R, Turdo A, D'Agostino D, Capone E, Stassi G, Todaro M, Di Ilio C, Sala G, Piantelli M, Negrini M, Veronese A, De Laurenzi V. Cell Death Dis. 2015 Jul 16;6:e1823. doi: 10.1038/cddis.2015.192. PubMed
Trib3 Is Elevated in Parkinson's Disease and Mediates Death in Parkinson's Disease Models. Aime P, Sun X, Zareen N, Rao A, Berman Z, Volpicelli-Daley L, Bernd P, Crary JF, Levy OA, Greene LA. J Neurosci. 2015 Jul 29;35(30):10731-49. doi: 10.1523/JNEUROSCI.0614-15.2015. PubMed
Using Caco-2 Cells to Study Lipid Transport by the Intestine. Nauli AM, Whittimore JD. J Vis Exp. 2015 Aug 20;(102):e53086. doi: 10.3791/53086. PubMed
The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane. Baskin JM, Wu X, Christiano R, Oh MS, Schauder CM, Gazzerro E, Messa M, Baldassari S, Assereto S, Biancheri R, Zara F, Minetti C, Raimondi A, Simons M, Walther TC, Reinisch KM, De Camilli P. Nat Cell Biol. 2016 Jan;18(1):132-8. doi: 10.1038/ncb3271. Epub 2015 Nov 16. PubMed
Development of ovine chorionic somatomammotropin hormone-deficient pregnancies. Baker CM, Goetzmann LN, Cantlon JD, Jeckel KM, Winger QA, Anthony RV. Am J Physiol Regul Integr Comp Physiol. 2016 May 1;310(9):R837-46. doi: 10.1152/ajpregu.00311.2015. Epub 2016 Feb 17. PubMed
Neuronal Orphan G-Protein Coupled Receptor Proteins Mediate Plasmalogens-Induced Activation of ERK and Akt Signaling. Hossain MS, Mineno K, Katafuchi T. PLoS One. 2016 Mar 2;11(3):e0150846. doi: 10.1371/journal.pone.0150846. eCollection 2016. PubMed
Branch-PCR Constructed Stable shRNA Transcription Nanoparticles Have Long-Lasting RNAi Effect. Liu J, Wang R, Ma D, Li Y, Wei C, Xi Z. Chembiochem. 2016 Jun 2;17(11):1038-42. doi: 10.1002/cbic.201600047. Epub 2016 Apr 21. PubMed
Opposing Effects of Maternal Hypo- and Hyperthyroidism on the Stability of Thalamocortical Synapses in the Visual Cortex of Adult Offspring. Strobl MJ, Freeman D, Patel J, Poulsen R, Wendler CC, Rivkees SA, Coleman JE. Cereb Cortex. 2016 May 26. pii: bhw096. PubMed
The Rac-GAP alpha2-chimaerin regulates hippocampal dendrite and spine morphogenesis. Valdez CM, Murphy GG, Beg AA. Mol Cell Neurosci. 2016 Jun 11;75:14-26. doi: 10.1016/j.mcn.2016.06.002. PubMed
The Neuron-Specific Protein TMEM59L Mediates Oxidative Stress-Induced Cell Death. Zheng Q, Zheng X, Zhang L, Luo H, Qian L, Fu X, Liu Y, Gao Y, Niu M, Meng J, Zhang M, Bu G, Xu H, Zhang YW. Mol Neurobiol. 2016 Jun 21. PubMed
Ubiquitously expressed genes participate in cell-specific functions via alternative promoter usage. Feng G, Tong M, Xia B, Luo GZ, Wang M, Xie D, Wan H, Zhang Y, Zhou Q, Wang XJ. EMBO Rep. 2016 Sep;17(9):1304-13. doi: 10.15252/embr.201541476. Epub 2016 Jul 27. PubMed
Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex. Zhang X, Chen MH, Wu X, Kodani A, Fan J, Doan R, Ozawa M, Ma J, Yoshida N, Reiter JF, Black DL, Kharchenko PV, Sharp PA, Walsh CA. Cell. 2016 Aug 25;166(5):1147-1162.e15. doi: 10.1016/j.cell.2016.07.025. PubMed
Cadm3 (Necl-1) interferes with the activation of the PI3 kinase/Akt signaling cascade and inhibits Schwann cell myelination in vitro. Chen MS, Kim H, Jagot-Lacoussiere L, Maurel P. Glia. 2016 Dec;64(12):2247-2262. doi: 10.1002/glia.23072. Epub 2016 Sep 23. PubMed
Olig2-Targeted G-Protein-Coupled Receptor Gpr17 Regulates Oligodendrocyte Survival in Response to Lysolecithin-Induced Demyelination. Ou Z, Sun Y, Lin L, You N, Liu X, Li H, Ma Y, Cao L, Han Y, Liu M, Deng Y, Yao L, Lu QR, Chen Y. J Neurosci. 2016 Oct 12;36(41):10560-10573. PubMed
Defining the role of corticotropin releasing factor binding protein in alcohol consumption. Haass-Koffler CL, Henry AT, Melkus G, Simms JA, Naemmuddin M, Nielsen CK, Lasek AW, Magill M, Schwandt ML, Momenan R, Hodgkinson CA, Bartlett SE, Swift RM, Bonci A, Leggio L. Transl Psychiatry. 2016 Nov 15;6(11):e953. doi: 10.1038/tp.2016.208. PubMed
PAR1 Scaffolds TGFbetaRII to Downregulate TGF-beta Signaling and Activate ESC Differentiation to Endothelial Cells. Gong H, An S, Sassmann A, Liu M, Mastej V, Mittal M, Zhang W, Hong Z, Offermanns S, Rehman J, Malik AB. Stem Cell Reports. 2016 Dec 13;7(6):1050-1058. doi: 10.1016/j.stemcr.2016.10.006. Epub 2016 Nov 17. PubMed
MiR-590 Promotes Transdifferentiation of Porcine and Human Fibroblasts Toward a Cardiomyocyte-Like Fate by Directly Repressing Specificity Protein 1. Singh VP, Mathison M, Patel V, Sanagasetti D, Gibson BW, Yang J, Rosengart TK. J Am Heart Assoc. 2016 Nov 10;5(11). pii: e003922. PubMed
MicroRNA-202 maintains spermatogonial stem cells by inhibiting cell cycle regulators and RNA binding proteins. Chen J, Cai T, Zheng C, Lin X, Wang G, Liao S, Wang X, Gan H, Zhang D, Hu X, Wang S, Li Z, Feng Y, Yang F, Han C. Nucleic Acids Res. 2016 Dec 19. pii: gkw1287. doi: 10.1093/nar/gkw1287. PubMed
Nectin-like 4 Complexes with Choline Transporter-like Protein-1 and Regulates Schwann Cell Choline Homeostasis and Lipid Biogenesis in Vitro. Heffernan C, Jain MR, Liu T, Kim H, Barretto K, Li H, Maurel P. J Biol Chem. 2017 Mar 17;292(11):4484-4498. doi: 10.1074/jbc.M116.747816. Epub 2017 Jan 24. PubMed
Reduction of Ether-Type Glycerophospholipids, Plasmalogens, by NF-kappaB Signal Leading to Microglial Activation. Hossain MS, Abe Y, Ali F, Youssef M, Honsho M, Fujiki Y, Katafuchi T. J Neurosci. 2017 Apr 12;37(15):4074-4092. doi: 10.1523/JNEUROSCI.3941-15.2017. Epub 2017 Mar 14. PubMed
Glucose Can Epigenetically Alter the Gene Expression of Neurotrophic Factors in the Murine Brain Cells. Hossain MS, Oomura Y, Katafuchi T. Mol Neurobiol. 2017 May 13. doi: 10.1007/s12035-017-0578-3. PubMed
Unraveling the role of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha in the adaption process of human microvascular endothelial cells (HMEC-1) to hypoxia: Redundant HIF-dependent regulation of macrophage migration inhibitory factor. Hahne M, Schumann P, Mursell M, Strehl C, Hoff P, Buttgereit F, Gaber T. Microvasc Res. 2018 Mar;116:34-44. doi: 10.1016/j.mvr.2017.09.004. Epub 2017 Oct 6. PubMed
The Primate-Specific Gene TMEM14B Marks Outer Radial Glia Cells and Promotes Cortical Expansion and Folding. Liu J, Liu W, Yang L, Wu Q, Zhang H, Fang A, Li L, Xu X, Sun L, Zhang J, Tang F, Wang X. Cell Stem Cell. 2017 Nov 2;21(5):635-649.e8. doi: 10.1016/j.stem.2017.08.013. Epub 2017 Oct 12. PubMed
Gata6 in pluripotent stem cells enhance the potential to differentiate into cardiomyocytes. Yoon CH, Kim TW, Koh SJ, Choi YE, Hur J, Kwon YW, Cho HJ, Kim HS. BMB Rep. 2018 Feb;51(2):85-91. PubMed
Lentiviral Transduction of Rat Schwann Cells and Dorsal Root Ganglia Neurons for In Vitro Myelination Studies. Heffernan C, Maurel P. Methods Mol Biol. 2018;1739:177-193. doi: 10.1007/978-1-4939-7649-2_12. PubMed
Role for Wnt Signaling in Retinal Neuropil Development: Analysis via RNA-Seq and In Vivo Somatic CRISPR Mutagenesis. Sarin S, Zuniga-Sanchez E, Kurmangaliyev YZ, Cousins H, Patel M, Hernandez J, Zhang KX, Samuel MA, Morey M, Sanes JR, Zipursky SL. Neuron. 2018 Mar 22. pii: S0896-6273(18)30181-8. doi: 10.1016/j.neuron.2018.03.004. PubMed
Alcohol-mediated miR-34a modulates hepatocyte growth and apoptosis. Iwagami Y, Zou J, Zhang H, Cao K, Ji C, Kim M, Huang CK. J Cell Mol Med. 2018 Jun 5. doi: 10.1111/jcmm.13681. PubMed
Lipid raftassociated betaadducin participates in neutrophil migration. Yang C, Sui Z, Xu T, Liu W, Wang X, Zeng X. Mol Med Rep. 2018 Aug;18(2):1353-1360. doi: 10.3892/mmr.2018.9113. Epub 2018 May 31. PubMed
Epstein-Barr virus-encoded EBNA2 alters immune checkpoint PD-L1 expression by downregulating miR-34a in B-cell lymphomas. Anastasiadou E, Stroopinsky D, Alimperti S, Jiao AL, Pyzer AR, Cippitelli C, Pepe G, Severa M, Rosenblatt J, Etna MP, Rieger S, Kempkes B, Coccia EM, Sui SJH, Chen CS, Uccini S, Avigan D, Faggioni A, Trivedi P, Slack FJ. Leukemia. 2019 Jan;33(1):132-147. doi: 10.1038/s41375-018-0178-x. Epub 2018 Jun 26. PubMed
Optimisation of electroporation and lipofection protocols to derive the black tiger shrimp cell line (Penaeus monodon). Thansa K, Rungsiwiwut R, Kitiyanant N, Taengchaiyaphum S. Fish Shellfish Immunol. 2018 Oct;81:204-213. doi: 10.1016/j.fsi.2018.07.030. Epub 2018 Jul 17. PubMed
Plasmalogens Inhibit Endocytosis of Toll-like Receptor 4 to Attenuate the Inflammatory Signal in Microglial Cells. Ali F, Hossain MS, Sejimo S, Akashi K. Mol Neurobiol. 2018 Aug 20. pii: 10.1007/s12035-018-1307-2. doi: 10.1007/s12035-018-1307-2. PubMed
Regulation of energy rheostasis by the melanocortin-3 receptor. Ghamari-Langroudi M, Cakir I, Lippert RN, Sweeney P, Litt MJ, Ellacott KLJ, Cone RD. Sci Adv. 2018 Aug 22;4(8):eaat0866. doi: 10.1126/sciadv.aat0866. eCollection 2018 Aug. PubMed
Identification of the Human Skeletal Stem Cell. Chan CKF, Gulati GS, Sinha R, Tompkins JV, Lopez M, Carter AC, Ransom RC, Reinisch A, Wearda T, Murphy M, Brewer RE, Koepke LS, Marecic O, Manjunath A, Seo EY, Leavitt T, Lu WJ, Nguyen A, Conley SD, Salhotra A, Ambrosi TH, Borrelli MR, Siebel T, Chan K, Schallmoser K, Seita J, Sahoo D, Goodnough H, Bishop J, Gardner M, Majeti R, Wan DC, Goodman S, Weissman IL, Chang HY, Longaker MT. Cell. 2018 Sep 20;175(1):43-56.e21. doi: 10.1016/j.cell.2018.07.029. PubMed
Zeb1 Regulates the Symmetric Division of Mouse Lewis Lung Carcinoma Stem Cells through Numb mediated by miR-31. Wang J, Zhou T, Sun Z, Ye T, Zhou S, Li J, Liu Y, Kong L, Tang J, Liu D, Xing HR. Int J Biol Sci. 2018 Jul 28;14(11):1399-1410. doi: 10.7150/ijbs.27446. eCollection 2018. PubMed
Brain injury induces HIF-1alpha-dependent transcriptional activation of LRRK2 that exacerbates brain damage. Bae YH, Joo H, Bae J, Hyeon SJ, Her S, Ko E, Choi HG, Ryu H, Hur EM, Bu Y, Lee BD. Cell Death Dis. 2018 Nov 12;9(11):1125. doi: 10.1038/s41419-018-1180-y. PubMed
MiRNA-218 regulates osteoclast differentiation and inflammation response in periodontitis rats through Mmp9. Guo J, Zeng X, Miao J, Liu C, Wei F, Liu D, Zheng Z, Ting K, Wang C, Liu Y. Cell Microbiol. 2019 Apr;21(4):e12979. doi: 10.1111/cmi.12979. Epub 2019 Jan 15. PubMed
PUFA-Plasmalogens Attenuate the LPS-Induced Nitric Oxide Production by Inhibiting the NF-kB, p38 MAPK and JNK Pathways in Microglial Cells. Youssef M, Ibrahim A, Akashi K, Hossain MS. Neuroscience. 2019 Jan 15;397:18-30. doi: 10.1016/j.neuroscience.2018.11.030. Epub 2018 Nov 26. PubMed
Calcium oscillations coordinate feather mesenchymal cell movement by SHH dependent modulation of gap junction networks. Li A, Cho JH, Reid B, Tseng CC, He L, Tan P, Yeh CY, Wu P, Li Y, Widelitz RB, Zhou Y, Zhao M, Chow RH, Chuong CM. Nat Commun. 2018 Dec 18;9(1):5377. doi: 10.1038/s41467-018-07661-5. PubMed
Late onset obesity in mice with targeted deletion of potassium inward rectifier Kir7.1 from cells expressing the melanocortin-4 receptor. Anderson EJP, Ghamari-Langroudi M, Cakir I, Litt MJ, Chen V, Reggiardo RE, Millhauser GL, Cone RD. J Neuroendocrinol. 2019 Jan;31(1):e12670. doi: 10.1111/jne.12670. Epub 2019 Jan 20. PubMed
Impairment of chaperone-mediated autophagy affects neuronal homeostasis through altered expression of DJ-1 and CRMP-2 proteins. Brekk OR, Makridakis M, Mavroeidi P, Vlahou A, Xilouri M, Stefanis L. Mol Cell Neurosci. 2019 Mar;95:1-12. doi: 10.1016/j.mcn.2018.12.006. Epub 2018 Dec 15. PubMed
Spatial Cycling of Rab GTPase, Driven by the GTPase Cycle, Controls Rab's Subcellular Distribution. Voss S, Li F, Ratz A, Roger M, Wu YW. Biochemistry. 2019 Jan 29;58(4):276-285. doi: 10.1021/acs.biochem.8b00932. Epub 2019 Jan 11. PubMed
Cenpj Regulates Cilia Disassembly and Neurogenesis in the Developing Mouse Cortex. Ding W, Wu Q, Sun L, Pan NC, Wang X. J Neurosci. 2019 Mar 13;39(11):1994-2010. doi: 10.1523/JNEUROSCI.1849-18.2018. Epub 2019 Jan 9. PubMed
Genome-wide analysis of ETV1 targets: Insights into the role of ETV1 in tumor progression. Eid W, Abdel-Rehim W. J Cell Biochem. 2019 Jan 10. doi: 10.1002/jcb.28169. PubMed
p53 Loss in Breast Cancer Leads to Myc Activation, Increased Cell Plasticity, and Expression of a Mitotic Signature with Prognostic Value. Santoro A, Vlachou T, Luzi L, Melloni G, Mazzarella L, D'Elia E, Aobuli X, Pasi CE, Reavie L, Bonetti P, Punzi S, Casoli L, Sabo A, Moroni MC, Dellino GI, Amati B, Nicassio F, Lanfrancone L, Pelicci PG. Cell Rep. 2019 Jan 15;26(3):624-638.e8. doi: 10.1016/j.celrep.2018.12.071. PubMed
Nucleotide Modification Alters MicroRNA-Dependent Silencing of MicroRNA Switches. Lockhart J, Canfield J, Mong EF, VanWye J, Totary-Jain H. Mol Ther Nucleic Acids. 2019 Mar 1;14:339-350. doi: 10.1016/j.omtn.2018.12.007. Epub 2018 Dec 18. PubMed
Adaptation to Host-Specific Bacterial Pathogens Drives Rapid Evolution of a Human Innate Immune Receptor. Adrian J, Bonsignore P, Hammer S, Frickey T, Hauck CR. Curr Biol. 2019 Feb 18;29(4):616-630.e5. doi: 10.1016/j.cub.2019.01.058. Epub 2019 Feb 7. PubMed
Ephrin-B3 controls excitatory synapse density through cell-cell competition for EphBs. Henderson NT, Le Marchand SJ, Hruska M, Hippenmeyer S, Luo L, Dalva MB. Elife. 2019 Feb 21;8. pii: 41563. doi: 10.7554/eLife.41563. PubMed
Mitochondrial Regulation of the Hippocampal Firing Rate Set Point and Seizure Susceptibility. Styr B, Gonen N, Zarhin D, Ruggiero A, Atsmon R, Gazit N, Braun G, Frere S, Vertkin I, Shapira I, Harel M, Heim LR, Katsenelson M, Rechnitz O, Fadila S, Derdikman D, Rubinstein M, Geiger T, Ruppin E, Slutsky I. Neuron. 2019 Jun 5;102(5):1009-1024.e8. doi: 10.1016/j.neuron.2019.03.045. Epub 2019 Apr 29. PubMed
Regulation of dendrite morphology and excitatory synapse formation by zDHHC15. Shah BS, Shimell JJ, Bamji SX. J Cell Sci. 2019 Jul 5;132(13). pii: jcs.230052. doi: 10.1242/jcs.230052. PubMed
Silencing of the foot-and-mouth disease virus internal ribosomal entry site by targeting relatively conserved region among serotypes. Matsui T, Handa Y, Kanda T, Tsukiyama-Kohara K. Virus Genes. 2019 Dec;55(6):786-794. doi: 10.1007/s11262-019-01696-6. Epub 2019 Jul 31. PubMed
miR-221 Targets QKI to Enhance the Tumorigenic Capacity of Human Colorectal Cancer Stem Cells. Mukohyama J, Isobe T, Hu Q, Hayashi T, Watanabe T, Maeda M, Yanagi H, Qian X, Yamashita K, Minami H, Mimori K, Sahoo D, Kakeji Y, Suzuki A, Dalerba P, Shimono Y. Cancer Res. 2019 Oct 15;79(20):5151-5158. doi: 10.1158/0008-5472.CAN-18-3544. Epub 2019 Aug 15. PubMed
Splicing Mutations Impairing CDKL5 Expression and Activity Can be Efficiently Rescued by U1snRNA-Based Therapy. Balestra D, Giorgio D, Bizzotto M, Fazzari M, Ben Zeev B, Pinotti M, Landsberger N, Frasca A. Int J Mol Sci. 2019 Aug 24;20(17). pii: ijms20174130. doi: 10.3390/ijms20174130. PubMed
SNX8 Enhances Non-amyloidogenic APP Trafficking and Attenuates Abeta Accumulation and Memory Deficits in an AD Mouse. Xie Y, Niu M, Ji C, Huang TY, Zhang C, Tian Y, Shi Z, Wang C, Zhao Y, Luo H, Can D, Xu H, Zhang YW, Zhang X. Front Cell Neurosci. 2019 Sep 6;13:410. doi: 10.3389/fncel.2019.00410. eCollection 2019. PubMed
Microtubule-associated protein 2 mediates induction of long-term potentiation in hippocampal neurons. Kim Y, Jang YN, Kim JY, Kim N, Noh S, Kim H, Queenan BN, Bellmore R, Mun JY, Park H, Rah JC, Pak DTS, Lee KJ. FASEB J. 2020 May;34(5):6965-6983. doi: 10.1096/fj.201902122RR. Epub 2020 Apr 1. PubMed
MicroRNA-93 targets WASF3 and functions as a metastasis suppressor in breast cancer. Shibuya N, Kakeji Y, Shimono Y. Cancer Sci. 2020 Jun;111(6):2093-2103. doi: 10.1111/cas.14423. Epub 2020 May 29. PubMed
Multiplexed drug testing of tumor slices using a microfluidic platform. Horowitz LF, Rodriguez AD, Dereli-Korkut Z, Lin R, Castro K, Mikheev AM, Monnat RJ Jr, Folch A, Rostomily RC. NPJ Precis Oncol. 2020 May 19;4:12. doi: 10.1038/s41698-020-0117-y. eCollection 2020. PubMed
Wildtype IDH1 affects cell migration by modulating the PI3K/AKT/mTOR pathway in primary glioblastoma cells. Shen X, Wu S, Zhang J, Li M, Xu F, Wang A, Lei Y, Zhu G. Mol Med Rep. 2020 Sep;22(3):1949-1957. doi: 10.3892/mmr.2020.11250. Epub 2020 Jun 18. PubMed
Dopamine Axon Targeting in the Nucleus Accumbens in Adolescence Requires Netrin-1. Cuesta S, Nouel D, Reynolds LM, Morgunova A, Torres-Berrio A, White A, Hernandez G, Cooper HM, Flores C. Front Cell Dev Biol. 2020 Jun 25;8:487. doi: 10.3389/fcell.2020.00487. eCollection 2020. PubMed
The miR-199a/214 Cluster Controls Nephrogenesis and Vascularization in a Human Embryonic Stem Cell Model. Bantounas I, Lopes FM, Rooney KM, Woolf AS, Kimber SJ. Stem Cell Reports. 2021 Jan 12;16(1):134-148. doi: 10.1016/j.stemcr.2020.11.007. Epub 2020 Dec 10. PubMed
Self-assembled miRNA-switch nanoparticles target denuded regions and prevent restenosis. Lockhart JH, VanWye J, Banerjee R, Wickline SA, Pan H, Totary-Jain H. Mol Ther. 2021 May 5;29(5):1744-1757. doi: 10.1016/j.ymthe.2021.01.032. Epub 2021 Feb 3. PubMed
Cancer-associated mutations reveal a novel role for EpCAM as an inhibitor of cathepsin-L and tumor cell invasion. Sankpal NV, Brown TC, Fleming TP, Herndon JM, Amaravati AA, Loynd AN, Gillanders WE. BMC Cancer. 2021 May 12;21(1):541. doi: 10.1186/s12885-021-08239-z. PubMed
Regulation of Neural Circuit Development by Cadherin-11 Provides Implications for Autism. Frei JA, Niescier RF, Bridi MS, Durens M, Nestor JE, Kilander MBC, Yuan X, Dykxhoorn DM, Nestor MW, Huang S, Blatt GJ, Lin YC. eNeuro. 2021 Jul 7;8(4). pii: ENEURO.0066-21.2021. doi: 10.1523/ENEURO.0066-21.2021. Print 2021 Jul-Aug. PubMed
Methods for Modulating the Pathway of NF-kappaB Using Short Hairpin RNA (ShRNA). Moretti M, Di Francesco B, Nolfi MDV, Angrisani A, De Smaele E. Methods Mol Biol. 2021;2366:95-107. doi: 10.1007/978-1-0716-1669-7_6. PubMed
HSP60-knockdown suppresses proliferation in colorectal cancer cells via activating the adenine/AMPK/mTOR signaling pathway. Guo J, Zhu S, Deng H, Xu R. Oncol Lett. 2021 Aug;22(2):630. doi: 10.3892/ol.2021.12891. Epub 2021 Jul 1. PubMed
Non-apoptotic function of caspase-8 confers prostate cancer enzalutamide resistance via NF-kappaB activation. Xia J, Zhang J, Wang L, Liu H, Wang J, Liu J, Liu Z, Zhu Y, Xu Y, Yang W, Yu Y. Cell Death Dis. 2021 Sep 4;12(9):833. doi: 10.1038/s41419-021-04126-4. PubMed
Downregulation of KLF4 activates embryonic and fetal globin mRNA expression in human erythroid progenitor cells. Khamphikham P, Jearawiriyapaisarn N, Tangprasittipap A, Hongeng S. Exp Ther Med. 2021 Oct;22(4):1105. doi: 10.3892/etm.2021.10539. Epub 2021 Aug 2. PubMed
Osteocalcin attenuates oligodendrocyte differentiation and myelination via GPR37 signaling in the mouse brain. Qian Z, Li H, Yang H, Yang Q, Lu Z, Wang L, Chen Y, Li X. Sci Adv. 2021 Oct 22;7(43):eabi5811. doi: 10.1126/sciadv.abi5811. Epub 2021 Oct 22. PubMed
Control of protein synthesis and memory by GluN3A-NMDA receptors through inhibition of GIT1/mTORC1 assembly. Conde-Dusman MJ, Dey PN, Elia-Zudaire O, Rabaneda LG, Garcia-Lira C, Grand T, Briz V, Velasco ER, Andero R, Ninerola S, Barco A, Paoletti P, Wesseling JF, Gardoni F, Tavalin SJ, Perez-Otano I. Elife. 2021 Nov 17;10. pii: 71575. doi: 10.7554/eLife.71575. PubMed
HDLs extract lipophilic drugs from cells. Zheng A, Dubuis G, Georgieva M, Mendes Ferreira CS, Serulla M, Del Carmen Conde Rubio M, Trofimenko E, Mercier T, Decosterd L, Widmann C. J Cell Sci. 2022 Mar 1;135(5):jcs258644. doi: 10.1242/jcs.258644. Epub 2022 Jan 31. PubMed
The nucleolar delta isoform of adapter protein SH2B1 enhances morphological complexity and function of cultured neurons. Cote JL, Vander PB, Ellis M, Cline JM, Svezhova N, Doche ME, Maures TJ, Choudhury TA, Kong S, Klaft OGJ, Joe RM, Argetsinger LS, Carter-Su C. J Cell Sci. 2022 Feb 1;135(3):jcs259179. doi: 10.1242/jcs.259179. Epub 2022 Feb 10. PubMed
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Associated Plasmids

Plasmalogens, the Vinyl Ether-Linked Glycerophospholipids, Enhance Learning and Memory by Regulating Brain-Derived Neurotrophic Factor. Hossain MS, Mawatari S, Fujino T. Front Cell Dev Biol. 2022 Feb 9;10:828282. doi: 10.3389/fcell.2022.828282. eCollection 2022. PubMed
Down-regulation of the transcriptional repressor ZNF802 (JAZF1) reactivates fetal hemoglobin in beta(0)-thalassemia/HbE. Wongborisuth C, Chumchuen S, Sripichai O, Anurathaphan U, Sathirapongsasuti N, Songdej D, Tangprasittipap A, Hongeng S. Sci Rep. 2022 Mar 23;12(1):4952. doi: 10.1038/s41598-022-08920-8. PubMed
The Anti-Glucocorticoid Receptor Antibody Clone 5E4: Raising Awareness of Unspecific Antibody Binding. Ehlers L, Kirchner M, Mertins P, Strehl C, Buttgereit F, Gaber T. Int J Mol Sci. 2022 May 2;23(9). pii: ijms23095049. doi: 10.3390/ijms23095049. PubMed
Metabolic lactate production coordinates vasculature development and progenitor behavior in the developing mouse neocortex. Dong X, Zhang Q, Yu X, Wang D, Ma J, Ma J, Shi SH. Nat Neurosci. 2022 Jul;25(7):865-875. doi: 10.1038/s41593-022-01093-7. Epub 2022 Jun 20. PubMed
Phagocytosis mediated by the human granulocyte receptor CEACAM3 is limited by the receptor-type protein tyrosine phosphatase PTPRJ. Goob G, Adrian J, Cossu C, Hauck CR. J Biol Chem. 2022 Sep;298(9):102269. doi: 10.1016/j.jbc.2022.102269. Epub 2022 Jul 16. PubMed
The retroelement Lx9 puts a brake on the immune response to virus infection. Bartonicek N, Rouet R, Warren J, Loetsch C, Rodriguez GS, Walters S, Lin F, Zahra D, Blackburn J, Hammond JM, Reis ALM, Deveson IW, Zammit N, Zeraati M, Grey S, Christ D, Mattick JS, Chtanova T, Brink R, Dinger ME, Weatheritt RJ, Sprent J, King C. Nature. 2022 Aug;608(7924):757-765. doi: 10.1038/s41586-022-05054-9. Epub 2022 Aug 10. PubMed
Targeting EGFR-dependent tumors by disrupting an ARF6-mediated sorting system. Guo H, Wang J, Ren S, Zheng LF, Zhuang YX, Li DL, Sun HH, Liu LY, Xie C, Wu YY, Wang HR, Deng X, Li P, Zhao TJ. Nat Commun. 2022 Oct 12;13(1):6004. doi: 10.1038/s41467-022-33788-7. PubMed
MYC-mediated silencing of miR-181a-5p promotes pathogenic Th17 responses by modulating AKT3-FOXO3 signaling. Chen S, Ma B, Li X, Zhang K, Wei Y, Du B, Liu X, Wei R, Li X, Nian H. iScience. 2022 Sep 23;25(10):105176. doi: 10.1016/j.isci.2022.105176. eCollection 2022 Oct 21. PubMed
The AhR-SRC axis as a therapeutic vulnerability in BRAFi-resistant melanoma. Paris A, Tardif N, Baietti FM, Berra C, Leclair HM, Leucci E, Galibert MD, Corre S. EMBO Mol Med. 2022 Dec 7;14(12):e15677. doi: 10.15252/emmm.202215677. Epub 2022 Oct 28. PubMed
Downregulation of SF3B2 protects CNS neurons in models of multiple sclerosis. Jeong YE, Rajbhandari L, Kim BW, Venkatesan A, Hoke A. Ann Clin Transl Neurol. 2023 Feb;10(2):246-265. doi: 10.1002/acn3.51717. Epub 2022 Dec 27. PubMed
Extracellular vesicles from mesenchymal stem cells reduce neuroinflammation in hippocampus and restore cognitive function in hyperammonemic rats. Izquierdo-Altarejos P, Cabrera-Pastor A, Martinez-Garcia M, Sanchez-Huertas C, Hernandez A, Moreno-Manzano V, Felipo V. J Neuroinflammation. 2023 Jan 2;20(1):1. doi: 10.1186/s12974-022-02688-4. PubMed
SLAMR, a synaptically targeted lncRNA, facilitates the consolidation of contextual fear memory. Espadas I, Wingfield J, Brinman E, Ghosh I, Chanda K, Nakahata Y, Bauer K, Raveendra B, Kiebler M, Yasuda R, Rangaraju V, Puthanveettil S. Res Sq. 2023 Mar 14:rs.3.rs-2489387. doi: 10.21203/rs.3.rs-2489387/v1. Preprint. PubMed
HAPLN1 potentiates peritoneal metastasis in pancreatic cancer. Wiedmann L, De Angelis Rigotti F, Vaquero-Siguero N, Donato E, Espinet E, Moll I, Alsina-Sanchis E, Bohnenberger H, Fernandez-Florido E, Mulfarth R, Vacca M, Gerwing J, Conradi LC, Strobel P, Trumpp A, Mogler C, Fischer A, Rodriguez-Vita J. Nat Commun. 2023 Apr 24;14(1):2353. doi: 10.1038/s41467-023-38064-w. PubMed
A genome-wide genetic screen identifies CYRI-B as a negative regulator of CEACAM3-mediated phagocytosis. Kuiper JWP, Krause J, Potgeter L, Adrian J, Hauck CR. J Cell Sci. 2023 Jun 1;136(11):jcs260771. doi: 10.1242/jcs.260771. Epub 2023 Jun 2. PubMed
The cell cycle protein MAD2 facilitates endocytosis of the serotonin transporter in the neuronal soma. Koban F, Freissmuth M. EMBO Rep. 2023 Oct 9;24(10):e53408. doi: 10.15252/embr.202153408. Epub 2023 Aug 2. PubMed
Human OTUD6B positively regulates type I IFN antiviral innate immune responses by deubiquitinating and stabilizing IRF3. Wang J, Zheng H, Dong C, Xiong S. mBio. 2023 Oct 31;14(5):e0033223. doi: 10.1128/mbio.00332-23. Epub 2023 Aug 31. PubMed
Development of short hairpin RNA expression vectors targeting the internal ribosomal entry site of the classical swine fever virus genomic RNA. Okamoto R, Ito N, Ide Y, Kitab B, Sakoda Y, Tsukiyama-Kohara K. BMC Biotechnol. 2023 Sep 8;23(1):37. doi: 10.1186/s12896-023-00805-6. PubMed
Y-27632 acts beyond ROCK inhibition to maintain epidermal stem-like cells in culture. Witkowski TA, Li B, Andersen JG, Kumar B, Mroz EA, Rocco JW. J Cell Sci. 2023 Sep 1;136(17):jcs260990. doi: 10.1242/jcs.260990. Epub 2023 Sep 12. PubMed
Design and deep learning of synthetic B-cell-specific promoters. Fu ZH, He SZ, Wu Y, Zhao GR. Nucleic Acids Res. 2023 Nov 27;51(21):11967-11979. doi: 10.1093/nar/gkad930. PubMed
Transglutaminase 2 Prevents Premature Senescence and Promotes Osteoblastic Differentiation of Mesenchymal Stem Cells through NRF2 Activation. Lee SJ, Shin JW, Kwon MA, Lee KB, Kim HJ, Lee JH, Kang HS, Jun JK, Cho SY, Kim IG. Stem Cells Int. 2023 Oct 20;2023:8815888. doi: 10.1155/2023/8815888. eCollection 2023. PubMed
The subset of peroxisomal tail-anchored proteins do not reach peroxisomes via ER, instead mitochondria can be involved. Somborac T, Lutfullahoglu Bal G, Fatima K, Vihinen H, Paatero A, Jokitalo E, Paavilainen VO, Konovalova S. PLoS One. 2023 Dec 1;18(12):e0295047. doi: 10.1371/journal.pone.0295047. eCollection 2023. PubMed

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