pcDNA3 Flag FKHR AAA mutant Citations (24)

Originally described in: Negative regulation of the forkhead transcription factor FKHR by Akt.
Tang ED, Nunez G, Barr FG, Guan KL J Biol Chem. 1999 Jun 11. 274(24):16741-6. PubMed Journal

---

Articles Citing pcDNA3 Flag FKHR AAA mutant

Articles
O-GlcNAc regulates FoxO activation in response to glucose. Housley MP, Rodgers JT, Udeshi ND, Kelly TJ, Shabanowitz J, Hunt DF, Puigserver P, Hart GW. J Biol Chem. 2008 Jun 13. 283(24):16283-92. PubMed
A PGC-1alpha-O-GlcNAc transferase complex regulates FoxO transcription factor activity in response to glucose. Housley MP, Udeshi ND, Rodgers JT, Shabanowitz J, Puigserver P, Hunt DF, Hart GW. J Biol Chem. 2009 Feb 20. 284(8):5148-57. PubMed
Nicotinamide phosphoribosyltransferase imparts human endothelial cells with extended replicative lifespan and enhanced angiogenic capacity in a high glucose environment. Borradaile NM, Pickering JG. Aging Cell. 2009 Apr;8(2):100-12. doi: 10.1111/j.1474-9726.2009.00453.x. PubMed
Rapamycin-mediated FOXO1 inactivation reduces the anticancer efficacy of rapamycin. Abdelnour-Berchtold E, Cerantola Y, Roulin D, Dormond-Meuwly A, Demartines N, Dormond O. Anticancer Res. 2010 Mar;30(3):799-804. PubMed
Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells. Kobayashi H, Butler JM, O'Donnell R, Kobayashi M, Ding BS, Bonner B, Chiu VK, Nolan DJ, Shido K, Benjamin L, Rafii S. Nat Cell Biol. 2010 Nov;12(11):1046-56. doi: 10.1038/ncb2108. Epub 2010 Oct 24. PubMed
FHIT gene expression is repressed by mitogenic signaling through the PI3K/AKT/FOXO pathway. Kelley K, Berberich SJ. Am J Cancer Res. 2011;1(1):62-70. PubMed
Forkhead transcription factor FOXO1 inhibits nuclear factor-kappaB in gastric cancer. Yu DA, Yoon J, Ko YS, Park J, Kim SY, Kim MA, Kim JH, Jung J, Cheon Y, Lee HS, Kim WH, Lee BL. APMIS. 2014 Sep;122(9):848-55. doi: 10.1111/apm.12247. Epub 2014 Mar 28. PubMed
USP7 attenuates hepatic gluconeogenesis through modulation of FoxO1 gene promoter occupancy. Hall JA, Tabata M, Rodgers JT, Puigserver P. Mol Endocrinol. 2014 Jun;28(6):912-24. doi: 10.1210/me.2013-1420. Epub 2014 Apr 2. PubMed
FoxO transcription factors support oxidative stress resistance in human chondrocytes. Akasaki Y, Alvarez-Garcia O, Saito M, Carames B, Iwamoto Y, Lotz MK. Arthritis Rheumatol. 2014 Dec;66(12):3349-58. doi: 10.1002/art.38868. PubMed
Loss of FOXO1 promotes gastric tumour growth and metastasis through upregulation of human epidermal growth factor receptor 2/neu expression. Ko YS, Cho SJ, Park J, Kim Y, Choi YJ, Pyo JS, Jang BG, Park JW, Kim WH, Lee BL. Br J Cancer. 2015 Oct 20;113(8):1186-96. doi: 10.1038/bjc.2015.273. Epub 2015 Oct 8. PubMed
Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition. Singh BK, Sinha RA, Zhou J, Tripathi M, Ohba K, Wang ME, Astapova I, Ghosh S, Hollenberg AN, Gauthier K, Yen PM. J Biol Chem. 2016 Jan 1;291(1):198-214. doi: 10.1074/jbc.M115.668673. Epub 2015 Oct 9. PubMed
Active FOXO1 is a Key Determinant of Isoform-Specific Progesterone Receptor Transactivation and Senescence Programming. Diep CH, Knutson TP, Lange CA. Mol Cancer Res. 2015 Nov 17. pii: molcanres.0431.2015. PubMed
FOXO1 activation is an effector of SYK and AKT inhibition in tonic BCR signal-dependent diffuse large B-cell lymphomas. Szydlowski M, Kiliszek P, Sewastianik T, Jablonska E, Bialopiotrowicz E, Gorniak P, Polak A, Markowicz S, Nowak E, Grygorowicz MA, Prochorec-Sobieszek M, Szumera-Cieckiewicz A, Malenda A, Lech-Maranda E, Warzocha K, Juszczynski P. Blood. 2015 Nov 19. pii: blood-2015-06-654111. PubMed
FOXO1 Is Involved in the Effects of Cigarette Smoke Extract on Osteoblastic Differentiation of Cultured Human Periosteum-derived Cells. Sung IY, Park BC, Hah YS, Cho HY, Yun JW, Park BW, Kang YH, Kim HC, Hwang SC, Rho GJ, Kim UK, Woo DK, Oh SH, Byun JH. Int J Med Sci. 2015 Oct 21;12(11):881-90. doi: 10.7150/ijms.13172. eCollection 2015. PubMed
Lycopene Protects Keratinocytes Against UVB Radiation-Induced Carcinogenesis via Negative Regulation of FOXO3a Through the mTORC2/AKT Signaling Pathway. Chen P, Xu S, Qu J. J Cell Biochem. 2017 Jun 6. doi: 10.1002/jcb.26189. PubMed
FOXO1 reduces tumorsphere formation capacity and has crosstalk with LGR5 signaling in gastric cancer cells. Choi Y, Park J, Ko YS, Kim Y, Pyo JS, Jang BG, Kim MA, Lee JS, Chang MS, Lee BL. Biochem Biophys Res Commun. 2017 Nov 25;493(3):1349-1355. doi: 10.1016/j.bbrc.2017.09.163. Epub 2017 Sep 29. PubMed
FoxO transcription factors modulate autophagy and proteoglycan 4 in cartilage homeostasis and osteoarthritis. Matsuzaki T, Alvarez-Garcia O, Mokuda S, Nagira K, Olmer M, Gamini R, Miyata K, Akasaki Y, Su AI, Asahara H, Lotz MK. Sci Transl Med. 2018 Feb 14;10(428). pii: 10/428/eaan0746. doi: 10.1126/scitranslmed.aan0746. PubMed
DNA methylation and FoxO3a regulate PHLPP1 expression in chondrocytes. Castillejo Becerra CM, Mattson AM, Molstad DHH, Lorang IM, Westendorf JJ, Bradley EW. J Cell Biochem. 2018 Sep;119(9):7470-7478. doi: 10.1002/jcb.27056. Epub 2018 May 18. PubMed
Exogenous hydrogen sulfide attenuates the development of diabetic cardiomyopathy via the FoxO1 pathway. Ye P, Gu Y, Zhu YR, Chao YL, Kong XQ, Luo J, Ren XM, Zuo GF, Zhang DM, Chen SL. J Cell Physiol. 2018 Dec;233(12):9786-9798. doi: 10.1002/jcp.26946. Epub 2018 Aug 5. PubMed
MicroRNA-145 Regulates the Differentiation of Adipose Stem Cells Toward Microvascular Endothelial Cells and Promotes Angiogenesis. Arderiu G, Pena E, Aledo R, Juan-Babot O, Crespo J, Vilahur G, Onate B, Moscatiello F, Badimon L. Circ Res. 2019 Jun 21;125(1):74-89. doi: 10.1161/CIRCRESAHA.118.314290. Epub 2019 May 6. PubMed
FOXO1 Negates the Cooperative Action of FOXL2(C134W) and SMAD3 in CYP19 Expression in HGrC1 Cells by Sequestering SMAD3. Belli M, Secchi C, Stupack D, Shimasaki S. J Endocr Soc. 2019 Aug 29;3(11):2064-2081. doi: 10.1210/js.2019-00279. eCollection 2019 Nov 1. PubMed
FOXO1 and FOXO3 transcription factors have unique functions in meniscus development and homeostasis during aging and osteoarthritis. Lee KI, Choi S, Matsuzaki T, Alvarez-Garcia O, Olmer M, Grogan SP, D'Lima DD, Lotz MK. Proc Natl Acad Sci U S A. 2020 Feb 11;117(6):3135-3143. doi: 10.1073/pnas.1918673117. Epub 2020 Jan 24. PubMed
FOXO1 mitigates the SMAD3/FOXL2(C134W) transcriptomic effect in a model of human adult granulosa cell tumor. Secchi C, Benaglio P, Mulas F, Belli M, Stupack D, Shimasaki S. J Transl Med. 2021 Feb 27;19(1):90. doi: 10.1186/s12967-021-02754-0. PubMed
PTEN regulates adipose progenitor cell growth, differentiation, and replicative aging. Kirstein AS, Kehr S, Nebe M, Hanschkow M, Barth LAG, Lorenz J, Penke M, Breitfeld J, Le Duc D, Landgraf K, Korner A, Kovacs P, Stadler PF, Kiess W, Garten A. J Biol Chem. 2021 Aug;297(2):100968. doi: 10.1016/j.jbc.2021.100968. Epub 2021 Jul 14. PubMed

If you have published an article using this material, please email us at to have your article added to this page.