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SBE4-Luc Citations (52)

Plasmid Article: Human Smad3 and Smad4 are sequence-specific transcription activators.
Zawel L, Dai JL, Buckhaults P, Zhou S, Kinzler KW, Vogelstein B, Kern SE Mol Cell. 1998 Mar . 1(4):611-7.
PubMed Journal

Articles Citing SBE4-Luc

Articles
Epithelial to mesenchymal transition is impaired in colon cancer cells with microsatellite instability. Pino MS, Kikuchi H, Zeng M, Herraiz MT, Sperduti I, Berger D, Park DY, Iafrate AJ, Zukerberg LR, Chung DC. Gastroenterology. 2010 Apr;138(4):1406-17. doi: 10.1053/j.gastro.2009.12.010. Epub 2009 Dec 21. PubMed
Plasminogen activator inhibitor-1 is a transcriptional target of the canonical pathway of Wnt/beta-catenin signaling. He W, Tan R, Dai C, Li Y, Wang D, Hao S, Kahn M, Liu Y. J Biol Chem. 2010 Aug 6;285(32):24665-75. doi: 10.1074/jbc.M109.091256. Epub 2010 Jun 2. PubMed
The relationship between the Wnt/beta-catenin and TGF-beta/BMP signals in the intervertebral disc cell. Hiyama A, Sakai D, Tanaka M, Arai F, Nakajima D, Abe K, Mochida J. J Cell Physiol. 2011 May;226(5):1139-48. doi: 10.1002/jcp.22438. PubMed
Homeodomain protein DLX4 counteracts key transcriptional control mechanisms of the TGF-beta cytostatic program and blocks the antiproliferative effect of TGF-beta. Trinh BQ, Barengo N, Naora H. Oncogene. 2011 Jun 16;30(24):2718-29. doi: 10.1038/onc.2011.4. Epub 2011 Feb 7. PubMed
AMP-activated protein kinase inhibits TGF-beta-induced fibrogenic responses of hepatic stellate cells by targeting transcriptional coactivator p300. Lim JY, Oh MA, Kim WH, Sohn HY, Park SI. J Cell Physiol. 2012 Mar;227(3):1081-9. doi: 10.1002/jcp.22824. PubMed
Crosstalk between Nodal/activin and MAPK p38 signaling is essential for anterior-posterior axis specification. Clements M, Pernaute B, Vella F, Rodriguez TA. Curr Biol. 2011 Aug 9;21(15):1289-95. doi: 10.1016/j.cub.2011.06.048. Epub 2011 Jul 28. PubMed
Molecular imaging of TGFbeta-induced Smad2/3 phosphorylation reveals a role for receptor tyrosine kinases in modulating TGFbeta signaling. Nyati S, Schinske K, Ray D, Nyati MK, Ross BD, Rehemtulla A. Clin Cancer Res. 2011 Dec 1;17(23):7424-39. doi: 10.1158/1078-0432.CCR-11-1248. Epub 2011 Sep 26. PubMed
Lipopolysaccharide enhances transforming growth factor beta1-induced platelet-derived growth factor-B expression in bile duct epithelial cells. Kassel KM, Sullivan BP, Luyendyk JP. J Gastroenterol Hepatol. 2012 Apr;27(4):714-21. doi: 10.1111/j.1440-1746.2011.06941.x. PubMed
Synergistic and multidimensional regulation of plasminogen activator inhibitor type 1 expression by transforming growth factor type beta and epidermal growth factor. Song X, Thalacker FW, Nilsen-Hamilton M. J Biol Chem. 2012 Apr 6;287(15):12520-8. doi: 10.1074/jbc.M111.338079. Epub 2012 Feb 10. PubMed
Peroxisome proliferator-activated receptor beta/delta induces myogenesis by modulating myostatin activity. Bonala S, Lokireddy S, Arigela H, Teng S, Wahli W, Sharma M, McFarlane C, Kambadur R. J Biol Chem. 2012 Apr 13;287(16):12935-51. doi: 10.1074/jbc.M111.319145. Epub 2012 Feb 23. PubMed
AGR2 is a SMAD4-suppressible gene that modulates MUC1 levels and promotes the initiation and progression of pancreatic intraepithelial neoplasia. Norris AM, Gore A, Balboni A, Young A, Longnecker DS, Korc M. Oncogene. 2013 Aug 15;32(33):3867-76. doi: 10.1038/onc.2012.394. Epub 2012 Sep 3. PubMed
Transforming growth factor beta induces expression of connective tissue growth factor in hepatic progenitor cells through Smad independent signaling. Ding ZY, Jin GN, Liang HF, Wang W, Chen WX, Datta PK, Zhang MZ, Zhang B, Chen XP. Cell Signal. 2013 Oct;25(10):1981-92. doi: 10.1016/j.cellsig.2013.05.027. Epub 2013 May 28. PubMed
Loss of N-Myc interactor promotes epithelial-mesenchymal transition by activation of TGF-beta/SMAD signaling. Devine DJ, Rostas JW, Metge BJ, Das S, Mulekar MS, Tucker JA, Grizzle WE, Buchsbaum DJ, Shevde LA, Samant RS. Oncogene. 2014 May 15;33(20):2620-8. doi: 10.1038/onc.2013.215. Epub 2013 Jun 17. PubMed
Pancreatic cancer-associated retinoblastoma 1 dysfunction enables TGF-beta to promote proliferation. Gore AJ, Deitz SL, Palam LR, Craven KE, Korc M. J Clin Invest. 2014 Jan;124(1):338-52. doi: 10.1172/JCI71526. Epub 2013 Dec 16. PubMed
N-Hydroxycinnamide derivatives of osthole inhibit cell migration and invasion by suppressing Smad2 and Akt pathways in human colorectal adenocarcinoma cells. Liu LY, Huang WJ, Ho FM, Lin RJ, Lin SY, Suk FM, Liang YC. Chem Biol Interact. 2014 Jun 25;217:1-8. doi: 10.1016/j.cbi.2014.04.002. Epub 2014 Apr 12. PubMed
Presence and utility of intrinsically disordered regions in kinases. Kathiriya JJ, Pathak RR, Clayman E, Xue B, Uversky VN, Dave V. Mol Biosyst. 2014 Nov;10(11):2876-88. doi: 10.1039/c4mb00224e. PubMed
K153R polymorphism in myostatin gene increases the rate of promyostatin activation by furin. Szlama G, Trexler M, Buday L, Patthy L. FEBS Lett. 2015 Jan 30;589(3):295-301. doi: 10.1016/j.febslet.2014.12.011. Epub 2014 Dec 25. PubMed
Curcumin and emodin down-regulate TGF-beta signaling pathway in human cervical cancer cells. Thacker PC, Karunagaran D. PLoS One. 2015 Mar 18;10(3):e0120045. doi: 10.1371/journal.pone.0120045. eCollection 2015. PubMed
Global Developmental Gene Programing Involves a Nuclear Form of Fibroblast Growth Factor Receptor-1 (FGFR1). Terranova C, Narla ST, Lee YW, Bard J, Parikh A, Stachowiak EK, Tzanakakis ES, Buck MJ, Birkaya B, Stachowiak MK. PLoS One. 2015 Apr 29;10(4):e0123380. doi: 10.1371/journal.pone.0123380. eCollection 2015. PubMed
Synergistic interaction between the fibroblast growth factor and bone morphogenetic protein signaling pathways in lens cells. Boswell BA, Musil LS. Mol Biol Cell. 2015 Jul 1;26(13):2561-72. doi: 10.1091/mbc.E15-02-0117. Epub 2015 May 6. PubMed
Novel Function of Rev-erbalpha in Promoting Brown Adipogenesis. Nam D, Chatterjee S, Yin H, Liu R, Lee J, Yechoor VK, Ma K. Sci Rep. 2015 Jun 10;5:11239. doi: 10.1038/srep11239. PubMed
A Key Role for Leukemia Inhibitory Factor in C26 Cancer Cachexia. Seto DN, Kandarian SC, Jackman RW. J Biol Chem. 2015 Jun 19. pii: jbc.M115.638411. PubMed
Hypoxia induces calpain activity and degrades SMAD2 to attenuate TGFbeta signaling in macrophages. Cui W, Zhou J, Dehne N, Brune B. Cell Biosci. 2015 Jul 4;5:36. doi: 10.1186/s13578-015-0026-x. eCollection 2015. PubMed
Inorganic Arsenic Related Changes in the Stromal Tumor Microenvironment in a Prostate Cancer Cell-Conditioned Media Model. Shearer JJ, Wold EA, Umbaugh CS, Lichti CF, Nilsson CL, Figueiredo ML. Environ Health Perspect. 2015 Nov 20. PubMed
Upregulation of flotillin-1 promotes invasion and metastasis by activating TGF-beta signaling in nasopharyngeal carcinoma. Cao S, Cui Y, Xiao H, Mai M, Wang C, Xie S, Yang J, Wu S, Li J, Song L, Guo X, Lin C. Oncotarget. 2016 Jan 26;7(4):4252-64. doi: 10.18632/oncotarget.6483. PubMed
c-Jun N-terminal kinase inhibitor favors transforming growth factor-beta to antagonize hepatitis B virus X protein-induced cell growth promotion in hepatocellular carcinoma. Wu YH, Ai X, Liu FY, Liang HF, Zhang BX, Chen XP. Mol Med Rep. 2016 Feb;13(2):1345-52. doi: 10.3892/mmr.2015.4644. Epub 2015 Dec 4. PubMed
Low expression of galectin-3 is associated with poor survival in node-positive breast cancers and mesenchymal phenotype in breast cancer stem cells. Ilmer M, Mazurek N, Gilcrease MZ, Byrd JC, Woodward WA, Buchholz TA, Acklin K, Ramirez K, Hafley M, Alt E, Vykoukal J, Bresalier RS. Breast Cancer Res. 2016 Sep 29;18(1):97. PubMed
RhoA controls retinoid signaling by ROCK dependent regulation of retinol metabolism. Garcia-Mariscal A, Peyrollier K, Basse A, Pedersen E, Ruhl R, van Hengel J, Brakebusch C. Small GTPases. 2016 Oct 18:1-12. PubMed
Hydroxylases regulate intestinal fibrosis through the suppression of ERK-mediated TGF-beta1 signaling. Manresa MC, Tambuwala MM, Radhakrishnan P, Harnoss JM, Brown E, Cavadas MA, Keogh CE, Cheong A, Barrett KE, Cummins EP, Schneider M, Taylor CT. Am J Physiol Gastrointest Liver Physiol. 2016 Dec 1;311(6):G1076-G1090. doi: 10.1152/ajpgi.00229.2016. Epub 2016 Oct 27. PubMed
Sterol Regulatory Element Binding Protein (SREBP)-1 is a novel regulator of the Transforming Growth Factor (TGF)-beta receptor I (TbetaRI) through exosomal secretion. Van Krieken R, Chen G, Gao B, Read J, Al Saleh HA, Li R, Al-Nedawi K, Krepinsky JC. Cell Signal. 2017 Jan;29:158-167. doi: 10.1016/j.cellsig.2016.11.004. Epub 2016 Nov 5. PubMed
An iPSC-derived vascular model of Marfan syndrome identifies key mediators of smooth muscle cell death. Granata A, Serrano F, Bernard WG, McNamara M, Low L, Sastry P, Sinha S. Nat Genet. 2017 Jan;49(1):97-109. doi: 10.1038/ng.3723. Epub 2016 Nov 28. PubMed
Dual function of TGFbeta in lens epithelial cell fate: implications for secondary cataract. Boswell BA, Korol A, West-Mays JA, Musil LS. Mol Biol Cell. 2017 Apr 1;28(7):907-921. doi: 10.1091/mbc.E16-12-0865. Epub 2017 Feb 16. PubMed
A Novel Inhibitor of Homeodomain Interacting Protein Kinase 2 Mitigates Kidney Fibrosis through Inhibition of the TGF-beta1/Smad3 Pathway. Liu R, Das B, Xiao W, Li Z, Li H, Lee K, He JC. J Am Soc Nephrol. 2017 Jul;28(7):2133-2143. doi: 10.1681/ASN.2016080841. Epub 2017 Feb 20. PubMed
Unconventional MAPK-GSK-3beta Pathway Behind Atypical Epithelial-Mesenchymal Transition In Hepatocellular Carcinoma. Parveen S, Vedagiri D, Nair HG, Parthasarathy H, Harshan KH. Sci Rep. 2017 Aug 18;7(1):8842. doi: 10.1038/s41598-017-09179-0. PubMed
Ascorbic acid promotes a TGFbeta1-induced myofibroblast phenotype switch. Piersma B, Wouters OY, de Rond S, Boersema M, Gjaltema RAF, Bank RA. Physiol Rep. 2017 Sep;5(17). pii: 5/17/e13324. doi: 10.14814/phy2.13324. PubMed
R-Spondin1/LGR5 Activates TGFbeta Signaling and Suppresses Colon Cancer Metastasis. Zhou X, Geng L, Wang D, Yi H, Talmon G, Wang J. Cancer Res. 2017 Dec 1;77(23):6589-6602. doi: 10.1158/0008-5472.CAN-17-0219. Epub 2017 Sep 22. PubMed
Dynamic regulation of canonical TGFbeta signalling by endothelial transcription factor ERG protects from liver fibrogenesis. Dufton NP, Peghaire CR, Osuna-Almagro L, Raimondi C, Kalna V, Chuahan A, Webb G, Yang Y, Birdsey GM, Lalor P, Mason JC, Adams DH, Randi AM. Nat Commun. 2017 Oct 12;8(1):895. doi: 10.1038/s41467-017-01169-0. PubMed
Loss of CYLD promotes cell invasion via ALK5 stabilization in oral squamous cell carcinoma. Shinriki S, Jono H, Maeshiro M, Nakamura T, Guo J, Li JD, Ueda M, Yoshida R, Shinohara M, Nakayama H, Matsui H, Ando Y. J Pathol. 2018 Mar;244(3):367-379. doi: 10.1002/path.5019. Epub 2018 Feb 1. PubMed
PHD3 Controls Lung Cancer Metastasis and Resistance to EGFR Inhibitors through TGFalpha. Dopeso H, Jiao HK, Cuesta AM, Henze AT, Jurida L, Kracht M, Acker-Palmer A, Garvalov BK, Acker T. Cancer Res. 2018 Apr 1;78(7):1805-1819. doi: 10.1158/0008-5472.CAN-17-1346. Epub 2018 Jan 16. PubMed
Dysregulation of the MiR-449b target TGFBI alters the TGFbeta pathway to induce cisplatin resistance in nasopharyngeal carcinoma. Bissey PA, Law JH, Bruce JP, Shi W, Renoult A, Chua MLK, Yip KW, Liu FF. Oncogenesis. 2018 May 22;7(5):40. doi: 10.1038/s41389-018-0050-x. PubMed
The MAPK Erk5 is necessary for proper skeletogenesis involving a Smurf-Smad-Sox9 molecular axis. Iezaki T, Fukasawa K, Horie T, Park G, Robinson S, Nakaya M, Fujita H, Onishi Y, Ozaki K, Kanayama T, Hiraiwa M, Kitaguchi Y, Kaneda K, Yoneda Y, Takarada T, Guo XE, Kurose H, Hinoi E. Development. 2018 Jul 26;145(14). pii: dev.164004. doi: 10.1242/dev.164004. PubMed
JNK regulates muscle remodeling via myostatin/SMAD inhibition. Lessard SJ, MacDonald TL, Pathak P, Han MS, Coffey VG, Edge J, Rivas DA, Hirshman MF, Davis RJ, Goodyear LJ. Nat Commun. 2018 Aug 2;9(1):3030. doi: 10.1038/s41467-018-05439-3. PubMed
Rapamycin Upregulates Connective Tissue Growth Factor Expression in Hepatic Progenitor Cells Through TGF-beta-Smad2 Dependent Signaling. Wu Y, Wang W, Peng XM, He Y, Xiong YX, Liang HF, Chu L, Zhang BX, Ding ZY, Chen XP. Front Pharmacol. 2018 Aug 8;9:877. doi: 10.3389/fphar.2018.00877. eCollection 2018. PubMed
Combined Proteomic and In Silico Target Identification Reveal a Role for 5-Lipoxygenase in Developmental Signaling Pathways. Brand S, Roy S, Schroder P, Rathmer B, Roos J, Kapoor S, Patil S, Pommerenke C, Maier T, Janning P, Eberth S, Steinhilber D, Schade D, Schneider G, Kumar K, Ziegler S, Waldmann H. Cell Chem Biol. 2018 Sep 20;25(9):1095-1106.e23. doi: 10.1016/j.chembiol.2018.05.016. Epub 2018 Jun 28. PubMed
Expression of the Hutchinson-Gilford Progeria Mutation Leads to Aberrant Dentin Formation. Choi H, Kim TH, Jeong JK, Strandgren C, Eriksson M, Cho ES. Sci Rep. 2018 Oct 18;8(1):15368. doi: 10.1038/s41598-018-33764-6. PubMed
Natural Killer-Derived Exosomal miR-186 Inhibits Neuroblastoma Growth and Immune Escape Mechanisms. Neviani P, Wise PM, Murtadha M, Liu CW, Wu CH, Jong AY, Seeger RC, Fabbri M. Cancer Res. 2019 Mar 15;79(6):1151-1164. doi: 10.1158/0008-5472.CAN-18-0779. Epub 2018 Dec 12. PubMed
The cirrhotic liver is depleted of docosahexaenoic acid (DHA), a key modulator of NF-kappaB and TGFbeta pathways in hepatic stellate cells. Enguita M, Razquin N, Pamplona R, Quiroga J, Prieto J, Fortes P. Cell Death Dis. 2019 Jan 8;10(1):14. doi: 10.1038/s41419-018-1243-0. PubMed
Zfp423 Regulates Skeletal Muscle Regeneration and Proliferation. Addison WN, Hall KC, Kokabu S, Matsubara T, Fu MM, Gori F, Baron R. Mol Cell Biol. 2019 Apr 2;39(8). pii: MCB.00447-18. doi: 10.1128/MCB.00447-18. Print 2019 Apr 15. PubMed
Hyaluronan-mediated motility receptor confers resistance to chemotherapy via TGFbeta/Smad2-induced epithelial-mesenchymal transition in gastric cancer. Zhang H, Ren L, Ding Y, Li F, Chen X, Ouyang Y, Zhang Y, Zhang D. FASEB J. 2019 May;33(5):6365-6377. doi: 10.1096/fj.201802186R. Epub 2019 Feb 25. PubMed
EZH2 Regulates Protein Stability via Recruiting USP7 to Mediate Neuronal Gene Expression in Cancer Cells. Lei A, Chen L, Zhang M, Yang X, Xu L, Cao N, Zhang Z, Cao Y. Front Genet. 2019 May 3;10:422. doi: 10.3389/fgene.2019.00422. eCollection 2019. PubMed
Platyconic Acid A, Platycodi Radix-Derived Saponin, Suppresses TGF-1-induced Activation of Hepatic Stellate Cells via Blocking SMAD and Activating the PPAR Signaling Pathway. Choi JH, Kim SM, Lee GH, Jin SW, Lee HS, Chung YC, Jeong HG. Cells. 2019 Nov 29;8(12). pii: cells8121544. doi: 10.3390/cells8121544. PubMed
SRF-MRTF signaling suppresses brown adipocyte development by modulating TGF-beta/BMP pathway. Liu R, Xiong X, Nam D, Yechoor V, Ma K. Mol Cell Endocrinol. 2020 Jun 27:110920. doi: 10.1016/j.mce.2020.110920. PubMed

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