Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

Addgene

pLenti X1 Puro DEST (694-6) Citations (21)

Originally described in: A versatile viral system for expression and depletion of proteins in mammalian cells.
Campeau E, Ruhl VE, Rodier F, Smith CL, Rahmberg BL, Fuss JO, Campisi J, Yaswen P, Cooper PK, Kaufman PD. PLoS One. 2009 Aug 6;4(8):e6529.
PubMed Journal

Articles Citing pLenti X1 Puro DEST (694-6)

Articles
An essential role for Ran GTPase in epithelial ovarian cancer cell survival. Barres V, Ouellet V, Lafontaine J, Tonin PN, Provencher DM, Mes-Masson AM. Mol Cancer. 2010 Oct 13;9:272. doi: 10.1186/1476-4598-9-272. PubMed
Generation of assays and antibodies to facilitate the study of human 5'-tyrosyl DNA phosphodiesterase. Thomson G, Watson A, Caldecott K, Denneny O, Depledge P, Hamilton N, Hopkins G, Jordan A, Morrow C, Raoof A, Waddell I, Ogilvie D. Anal Biochem. 2013 May 15;436(2):145-50. doi: 10.1016/j.ab.2013.02.001. Epub 2013 Feb 12. PubMed
Combined mutation of Vhl and Trp53 causes renal cysts and tumours in mice. Albers J, Rajski M, Schonenberger D, Harlander S, Schraml P, von Teichman A, Georgiev S, Wild PJ, Moch H, Krek W, Frew IJ. EMBO Mol Med. 2013 Jun;5(6):949-64. doi: 10.1002/emmm.201202231. Epub 2013 Apr 22. PubMed
Parallel measurement of dynamic changes in translation rates in single cells. Han K, Jaimovich A, Dey G, Ruggero D, Meyuhas O, Sonenberg N, Meyer T. Nat Methods. 2014 Jan;11(1):86-93. doi: 10.1038/nmeth.2729. Epub 2013 Nov 10. PubMed

Associated Plasmids

Treatment-induced cell cycle kinetics dictate tumor response to chemotherapy. Hallett RM, Huang C, Motazedian A, Auf der Mauer S, Pond GR, Hassell JA, Nordon RE, Draper JS. Oncotarget. 2015 Mar 30;6(9):7040-52. PubMed
hVGAT-mCherry: A novel molecular tool for analysis of GABAergic neurons derived from human pluripotent stem cells. DeRosa BA, Belle KC, Thomas BJ, Cukier HN, Pericak-Vance MA, Vance JM, Dykxhoorn DM. Mol Cell Neurosci. 2015 Sep;68:244-57. doi: 10.1016/j.mcn.2015.08.007. Epub 2015 Aug 16. PubMed
Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice. Maresch R, Mueller S, Veltkamp C, Ollinger R, Friedrich M, Heid I, Steiger K, Weber J, Engleitner T, Barenboim M, Klein S, Louzada S, Banerjee R, Strong A, Stauber T, Gross N, Geumann U, Lange S, Ringelhan M, Varela I, Unger K, Yang F, Schmid RM, Vassiliou GS, Braren R, Schneider G, Heikenwalder M, Bradley A, Saur D, Rad R. Nat Commun. 2016 Feb 26;7:10770. doi: 10.1038/ncomms10770. PubMed
Protein Sialylation Regulates a Gene Expression Signature that Promotes Breast Cancer Cell Pathogenicity. Kohnz RA, Roberts LS, DeTomaso D, Bideyan L, Yan P, Bandyopadhyay S, Goga A, Yosef N, Nomura DK. ACS Chem Biol. 2016 Aug 19;11(8):2131-9. doi: 10.1021/acschembio.6b00433. Epub 2016 Jul 22. PubMed
Regulation of the CUL3 Ubiquitin Ligase by a Calcium-Dependent Co-adaptor. McGourty CA, Akopian D, Walsh C, Gorur A, Werner A, Schekman R, Bautista D, Rape M. Cell. 2016 Oct 6;167(2):525-538.e14. doi: 10.1016/j.cell.2016.09.026. PubMed
Engulfed cadherin fingers are polarized junctional structures between collectively migrating endothelial cells. Hayer A, Shao L, Chung M, Joubert LM, Yang HW, Tsai FC, Bisaria A, Betzig E, Meyer T. Nat Cell Biol. 2016 Dec;18(12):1311-1323. doi: 10.1038/ncb3438. Epub 2016 Nov 14. PubMed

Associated Plasmids

Nipbl Interacts with Zfp609 and the Integrator Complex to Regulate Cortical Neuron Migration. van den Berg DL, Azzarelli R, Oishi K, Martynoga B, Urban N, Dekkers DH, Demmers JA, Guillemot F. Neuron. 2016 Dec 20. pii: S0896-6273(16)30915-1. doi: 10.1016/j.neuron.2016.11.047. PubMed
Crystal structure of Zen4 in the apo state reveals a missing conformation of kinesin. Guan R, Zhang L, Su QP, Mickolajczyk KJ, Chen GY, Hancock WO, Sun Y, Zhao Y, Chen Z. Nat Commun. 2017 Apr 10;8:14951. doi: 10.1038/ncomms14951. PubMed
A clinical drug library screen identifies clobetasol propionate as an NRF2 inhibitor with potential therapeutic efficacy in KEAP1 mutant lung cancer. Choi EJ, Jung BJ, Lee SH, Yoo HS, Shin EA, Ko HJ, Chang S, Kim SY, Jeon SM. Oncogene. 2017 Sep 14;36(37):5285-5295. doi: 10.1038/onc.2017.153. Epub 2017 May 15. PubMed
PI3K class II alpha regulates delta-opioid receptor export from the trans-Golgi network. Shiwarski DJ, Darr M, Telmer CA, Bruchez MP, Puthenveedu MA. Mol Biol Cell. 2017 Aug 1;28(16):2202-2219. doi: 10.1091/mbc.E17-01-0030. Epub 2017 May 31. PubMed
Epigenetic Reprogramming of Lineage-Committed Human Mammary Epithelial Cells Requires DNMT3A and Loss of DOT1L. Breindel JL, Skibinski A, Sedic M, Wronski-Campos A, Zhou W, Keller PJ, Mills J, Bradner J, Onder T, Kuperwasser C. Stem Cell Reports. 2017 Sep 12;9(3):943-955. doi: 10.1016/j.stemcr.2017.06.019. Epub 2017 Aug 3. PubMed
UVB-induced nuclear translocation of TC-PTP by AKT/14-3-3sigma axis inhibits keratinocyte survival and proliferation. Kim M, Morales LD, Baek M, Slaga TJ, DiGiovanni J, Kim DJ. Oncotarget. 2017 Oct 11;8(53):90674-90692. doi: 10.18632/oncotarget.21794. eCollection 2017 Oct 31. PubMed
A splice junction-targeted CRISPR approach (spJCRISPR) reveals human FOXO3B to be a protein-coding gene. Santo EE, Paik J. Gene. 2018 Oct 5;673:95-101. doi: 10.1016/j.gene.2018.06.048. Epub 2018 Jun 18. PubMed
EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation. Zingg D, Debbache J, Pena-Hernandez R, Antunes AT, Schaefer SM, Cheng PF, Zimmerli D, Haeusel J, Calcada RR, Tuncer E, Zhang Y, Bossart R, Wong KK, Basler K, Dummer R, Santoro R, Levesque MP, Sommer L. Cancer Cell. 2018 Jul 9;34(1):69-84.e14. doi: 10.1016/j.ccell.2018.06.001. Epub 2018 Jun 28. PubMed
Ash1 counteracts Polycomb repression independent of histone H3 lysine 36 methylation. Dorafshan E, Kahn TG, Glotov A, Savitsky M, Walther M, Reuter G, Schwartz YB. EMBO Rep. 2019 Apr;20(4). pii: embr.201846762. doi: 10.15252/embr.201846762. Epub 2019 Mar 4. PubMed
Sterol-regulated transmembrane protein TMEM86a couples LXR signaling to regulation of lysoplasmalogens in macrophages. van Wouw SAE, van den Berg M, El Ouraoui M, Meurs A, Kingma J, Ottenhoff R, Loix M, Hoeksema MA, Prange K, Pasterkamp G, Hendriks JJA, Bogie JFJ, van Klinken JB, Vaz FM, Jongejan A, de Winther MPJ, Zelcer N. J Lipid Res. 2023 Feb;64(2):100325. doi: 10.1016/j.jlr.2022.100325. Epub 2022 Dec 31. PubMed
LPA1-mediated inhibition of CXCR4 attenuates CXCL12-induced signaling and cell migration. Hong JM, Lee JW, Seen DS, Jeong JY, Huh WK. Cell Commun Signal. 2023 Sep 25;21(1):257. doi: 10.1186/s12964-023-01261-7. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.