pLenti CMV Puro LUC (w168-1) Citations (69)

Originally described in: A versatile viral system for expression and depletion of proteins in mammalian cells.
Campeau E, Ruhl VE, Rodier F, Smith CL, Rahmberg BL, Fuss JO, Campisi J, Yaswen P, Cooper PK, Kaufman PD. PLoS One. 2009 Aug 6;4(8):e6529. PubMed Journal

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Articles Citing pLenti CMV Puro LUC (w168-1)

Articles
Real-time bioluminescence and tomographic imaging of gastric cancer in a novel orthotopic mouse model. Hu H, Liu J, Yao L, Yin J, Su N, Liu X, Cao F, Liang J, Nie Y, Wu K. Oncol Rep. 2012 Jun;27(6):1937-43. doi: 10.3892/or.2012.1713. Epub 2012 Mar 7. PubMed
Androgen receptor-independent function of FoxA1 in prostate cancer metastasis. Jin HJ, Zhao JC, Ogden I, Bergan RC, Yu J. Cancer Res. 2013 Jun 15;73(12):3725-36. doi: 10.1158/0008-5472.CAN-12-3468. Epub 2013 Mar 28. PubMed
Immunological properties of extraembryonic human mesenchymal stromal cells derived from gestational tissue. Stubbendorff M, Deuse T, Hua X, Phan TT, Bieback K, Atkinson K, Eiermann TH, Velden J, Schroder C, Reichenspurner H, Robbins RC, Volk HD, Schrepfer S. Stem Cells Dev. 2013 Oct 1;22(19):2619-29. doi: 10.1089/scd.2013.0043. Epub 2013 Jun 29. PubMed
Human bone marrow niche chemoprotection mediated by cytochrome P450 enzymes. Alonso S, Su M, Jones JW, Ganguly S, Kane MA, Jones RJ, Ghiaur G. Oncotarget. 2015 Jun 20;6(17):14905-12. PubMed
Platform Technologies for Directly Reconstructing 3D Living Biomaterials. Jayasinghe SN, Auguste J, Scotton CJ. Adv Mater. 2015 Dec;27(47):7794-9. doi: 10.1002/adma.201503001. Epub 2015 Oct 28. PubMed
Enhancing DPYSL3 gene expression via a promoter-targeted small activating RNA approach suppresses cancer cell motility and metastasis. Li C, Jiang W, Hu Q, Li LC, Dong L, Chen R, Zhang Y, Tang Y, Thrasher JB, Liu CB, Li B. Oncotarget. 2016 Mar 23. doi: 10.18632/oncotarget.8290. PubMed
Genetic and pharmacological inhibition of TTK impairs pancreatic cancer cell line growth by inducing lethal chromosomal instability. Stratford JK, Yan F, Hill RA, Major MB, Graves LM, Der CJ, Yeh JJ. PLoS One. 2017 Apr 5;12(4):e0174863. doi: 10.1371/journal.pone.0174863. eCollection 2017. PubMed
Melanoma Suppressor Functions of the Carcinoma Oncogene FOXQ1. Bagati A, Bianchi-Smiraglia A, Moparthy S, Kolesnikova K, Fink EE, Lipchick BC, Kolesnikova M, Jowdy P, Polechetti A, Mahpour A, Ross J, Wawrzyniak JA, Yun DH, Paragh G, Kozlova NI, Berman AE, Wang J, Liu S, Nemeth MJ, Nikiforov MA. Cell Rep. 2017 Sep 19;20(12):2820-2832. doi: 10.1016/j.celrep.2017.08.057. PubMed
SSeCKS/AKAP12 scaffolding functions suppress B16F10-induced peritoneal metastasis by attenuating CXCL9/10 secretion by resident fibroblasts. Muramatsu M, Gao L, Peresie J, Balderman B, Akakura S, Gelman IH. Oncotarget. 2017 Aug 9;8(41):70281-70298. doi: 10.18632/oncotarget.20092. eCollection 2017 Sep 19. PubMed
A High-Content Screening of Anticancer Compounds Suggests the Multiple Tyrosine Kinase Inhibitor Ponatinib for Repurposing in Neuroblastoma Therapy. Sidarovich V, De Mariano M, Aveic S, Pancher M, Adami V, Gatto P, Pizzini S, Pasini L, Croce M, Parodi F, Cimmino F, Avitabile M, Emionite L, Cilli M, Ferrini S, Pagano A, Capasso M, Quattrone A, Tonini GP, Longo L. Mol Cancer Ther. 2018 Jul;17(7):1405-1415. doi: 10.1158/1535-7163.MCT-17-0841. Epub 2018 Apr 25. PubMed
MKAD-21 Suppresses the Oncogenic Activity of the miR-21/PPP2R2A/ERK Molecular Network in Bladder Cancer. Koutsioumpa M, Chen HW, O'Brien N, Koinis F, Mahurkar-Joshi S, Vorvis C, Soroosh A, Luo T, Issakhanian S, Pantuck AJ, Georgoulias V, Iliopoulos D, Slamon DJ, Drakaki A. Mol Cancer Ther. 2018 Jul;17(7):1430-1440. doi: 10.1158/1535-7163.MCT-17-1049. Epub 2018 Apr 27. PubMed
An orthotopic glioblastoma animal model suitable for high-throughput screenings. Pudelko L, Edwards S, Balan M, Nyqvist D, Al-Saadi J, Dittmer J, Almlof I, Helleday T, Brautigam L. Neuro Oncol. 2018 Oct 9;20(11):1475-1484. doi: 10.1093/neuonc/noy071. PubMed
Targeting S1PR1/STAT3 loop abrogates desmoplasia and chemosensitizes pancreatic cancer to gemcitabine. Lankadasari MB, Aparna JS, Mohammed S, James S, Aoki K, Binu VS, Nair S, Harikumar KB. Theranostics. 2018 Jun 13;8(14):3824-3840. doi: 10.7150/thno.25308. eCollection 2018. PubMed
Lysine methyltransferase 2D regulates pancreatic carcinogenesis through metabolic reprogramming. Koutsioumpa M, Hatziapostolou M, Polytarchou C, Tolosa EJ, Almada LL, Mahurkar-Joshi S, Williams J, Tirado-Rodriguez AB, Huerta-Yepez S, Karavias D, Kourea H, Poultsides GA, Struhl K, Dawson DW, Donahue TR, Fernandez-Zapico ME, Iliopoulos D. Gut. 2018 Oct 18. pii: gutjnl-2017-315690. doi: 10.1136/gutjnl-2017-315690. PubMed
Proteolysis targeting chimeric molecules as therapy for multiple myeloma: efficacy, biomarker and drug combinations. Lim SL, Damnernsawad A, Shyamsunder P, Chng WJ, Han BC, Xu L, Pan J, Pravin DP, Alkan S, Tyner JW, Koeffler HP. Haematologica. 2019 Jan 3. pii: haematol.2018.201483. doi: 10.3324/haematol.2018.201483. PubMed
Therapeutic efficacy of intra-articular delivery of encapsulated human mesenchymal stem cells on early stage osteoarthritis. McKinney JM, Doan TN, Wang L, Deppen J, Reece DS, Pucha KA, Ginn S, Levit RD, Willett NJ. Eur Cell Mater. 2019 Jan 29;37:42-59. doi: 10.22203/eCM.v037a04. PubMed
Restoration of tumour-growth suppression in vivo via systemic nanoparticle-mediated delivery of PTEN mRNA. Islam MA, Xu Y, Tao W, Ubellacker JM, Lim M, Aum D, Lee GY, Zhou K, Zope H, Yu M, Cao W, Oswald JT, Dinarvand M, Mahmoudi M, Langer R, Kantoff PW, Farokhzad OC, Zetter BR, Shi J. Nat Biomed Eng. 2018 Nov;2(11):850-864. doi: 10.1038/s41551-018-0284-0. Epub 2018 Sep 17. PubMed
Collagen Prolyl Hydroxylation-Dependent Metabolic Perturbation Governs Epigenetic Remodeling and Mesenchymal Transition in Pluripotent and Cancer Cells. D'Aniello C, Cermola F, Palamidessi A, Wanderlingh LG, Gagliardi M, Migliaccio A, Varrone F, Casalino L, Matarazzo MR, De Cesare D, Scita G, Patriarca EJ, Minchiotti G. Cancer Res. 2019 Jul 1;79(13):3235-3250. doi: 10.1158/0008-5472.CAN-18-2070. Epub 2019 May 6. PubMed
Genomic and Transcriptomic Determinants of Therapy Resistance and Immune Landscape Evolution during Anti-EGFR Treatment in Colorectal Cancer. Woolston A, Khan K, Spain G, Barber LJ, Griffiths B, Gonzalez-Exposito R, Hornsteiner L, Punta M, Patil Y, Newey A, Mansukhani S, Davies MN, Furness A, Sclafani F, Peckitt C, Jimenez M, Kouvelakis K, Ranftl R, Begum R, Rana I, Thomas J, Bryant A, Quezada S, Wotherspoon A, Khan N, Fotiadis N, Marafioti T, Powles T, Lise S, Calvo F, Guettler S, von Loga K, Rao S, Watkins D, Starling N, Chau I, Sadanandam A, Cunningham D, Gerlinger M. Cancer Cell. 2019 Jul 8;36(1):35-50.e9. doi: 10.1016/j.ccell.2019.05.013. PubMed
Characterization of HIV-1 CRF01_AE env Genes Derived from Recently Infected Indonesian Individuals. Sasaki M, Kotaki T, Khairunisa SQ, Tachibana S, Ophinni Y, Hayashi Y, Nasronudin, Kameoka M. AIDS Res Hum Retroviruses. 2019 Oct 3. doi: 10.1089/aid.2019.0179. PubMed
Dysregulation of Glutamate Transport Enhances Treg Function That Promotes VEGF Blockade Resistance in Glioblastoma. Long Y, Tao H, Karachi A, Grippin AJ, Jin L, Chang YE, Zhang W, Dyson KA, Hou AY, Na M, Deleyrolle LP, Sayour EJ, Rahman M, Mitchell DA, Lin Z, Huang J. Cancer Res. 2020 Feb 1;80(3):499-509. doi: 10.1158/0008-5472.CAN-19-1577. Epub 2019 Nov 13. PubMed
WDR5 inhibition halts metastasis dissemination by repressing the mesenchymal phenotype of breast cancer cells. Punzi S, Balestrieri C, D'Alesio C, Bossi D, Dellino GI, Gatti E, Pruneri G, Criscitiello C, Lovati G, Meliksetyan M, Carugo A, Curigliano G, Natoli G, Pelicci PG, Lanfrancone L. Breast Cancer Res. 2019 Nov 21;21(1):123. doi: 10.1186/s13058-019-1216-y. PubMed
AXL and CAV-1 play a role for MTH1 inhibitor TH1579 sensitivity in cutaneous malignant melanoma. Das I, Gad H, Brautigam L, Pudelko L, Tuominen R, Hoiom V, Almlof I, Rajagopal V, Hansson J, Helleday T, Egyhazi Brage S, Warpman Berglund U. Cell Death Differ. 2020 Jul;27(7):2081-2098. doi: 10.1038/s41418-019-0488-1. Epub 2020 Jan 9. PubMed
Using Bioengineered Bioluminescence to Track Stem Cell Transplantation In Vivo. Han D, Wu JC. Methods Mol Biol. 2020;2126:1-11. doi: 10.1007/978-1-0716-0364-2_1. PubMed
Actinomycin D Downregulates Sox2 and Improves Survival in Preclinical Models of Recurrent Glioblastoma. Taylor JT, Ellison S, Pandele A, Wood S, Nathan E, Forte G, Parker H, Zindy E, Elvin M, Dickson A, Williams KJ, Karabatsou K, McCabe M, McBain C, Bigger BW. Neuro Oncol. 2020 Mar 30. pii: 5813520. doi: 10.1093/neuonc/noaa051. PubMed
Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion. Su R, Dong L, Li Y, Gao M, Han L, Wunderlich M, Deng X, Li H, Huang Y, Gao L, Li C, Zhao Z, Robinson S, Tan B, Qing Y, Qin X, Prince E, Xie J, Qin H, Li W, Shen C, Sun J, Kulkarni P, Weng H, Huang H, Chen Z, Zhang B, Wu X, Olsen MJ, Muschen M, Marcucci G, Salgia R, Li L, Fathi AT, Li Z, Mulloy JC, Wei M, Horne D, Chen J. Cancer Cell. 2020 Jul 13;38(1):79-96.e11. doi: 10.1016/j.ccell.2020.04.017. Epub 2020 Jun 11. PubMed
Multiple myeloma: Combination therapy of BET proteolysis targeting chimeric molecule with CDK9 inhibitor. Lim SL, Xu L, Han BC, Shyamsunder P, Chng WJ, Koeffler HP. PLoS One. 2020 Jun 19;15(6):e0232068. doi: 10.1371/journal.pone.0232068. eCollection 2020. PubMed
Ovarian Cells Have Increased Proliferation in Response to Heparin-Binding Epidermal Growth Factor as Collagen Density Increases. Fogg KC, Renner CM, Christian H, Walker A, Marty-Santos L, Khan A, Olson WR, Parent C, O'Shea A, Wellik DM, Weisman PS, Kreeger PK. Tissue Eng Part A. 2020 Jul;26(13-14):747-758. doi: 10.1089/ten.tea.2020.0001. Epub 2020 Jun 25. PubMed
Dual roles of neutrophils in metastatic colonization are governed by the host NK cell status. Li P, Lu M, Shi J, Hua L, Gong Z, Li Q, Shultz LD, Ren G. Nat Commun. 2020 Sep 1;11(1):4387. doi: 10.1038/s41467-020-18125-0. PubMed
Co-culture Systems of Drug-Treated Acute Myeloid Leukemia Cells and T Cells for In Vitro and In Vivo Study. Li Y, Su R, Chen J. STAR Protoc. 2020 Sep 18;1(2). doi: 10.1016/j.xpro.2020.100097. Epub 2020 Aug 28. PubMed
Assessment of the WAP-Myc mouse mammary tumor model for spontaneous metastasis. Utz B, Turpin R, Lampe J, Pouwels J, Klefstrom J. Sci Rep. 2020 Oct 30;10(1):18733. doi: 10.1038/s41598-020-75411-z. PubMed
Chimeric antigen receptor-modified macrophages trigger systemic anti-tumour immunity. Niu Z, Chen G, Chang W, Sun P, Luo Z, Zhang H, Zhi L, Guo C, Chen H, Yin M, Zhu W. J Pathol. 2021 Mar;253(3):247-257. doi: 10.1002/path.5585. Epub 2020 Dec 4. PubMed
Cyclophosphamide and Vinorelbine Activate Stem-Like CD8(+) T Cells and Improve Anti-PD-1 Efficacy in Triple-Negative Breast Cancer. Falvo P, Orecchioni S, Hillje R, Raveane A, Mancuso P, Camisaschi C, Luzi L, Pelicci P, Bertolini F. Cancer Res. 2021 Feb 1;81(3):685-697. doi: 10.1158/0008-5472.CAN-20-1818. Epub 2020 Dec 2. PubMed
R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m(6)A/PFKP/LDHB axis. Qing Y, Dong L, Gao L, Li C, Li Y, Han L, Prince E, Tan B, Deng X, Wetzel C, Shen C, Gao M, Chen Z, Li W, Zhang B, Braas D, Ten Hoeve J, Sanchez GJ, Chen H, Chan LN, Chen CW, Ann D, Jiang L, Muschen M, Marcucci G, Plas DR, Li Z, Su R, Chen J. Mol Cell. 2021 Mar 4;81(5):922-939.e9. doi: 10.1016/j.molcel.2020.12.026. PubMed
Nuclear localization of p65 reverses therapy-induced senescence. Salunkhe S, Mishra SV, Nair J, Shah S, Gardi N, Thorat R, Sarkar D, Rajendra J, Kaur E, Dutt S. J Cell Sci. 2021 Mar 26;134(6). pii: jcs.253203. doi: 10.1242/jcs.253203. PubMed
RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors. Patel PS, Abraham KJ, Guturi KKN, Halaby MJ, Khan Z, Palomero L, Ho B, Duan S, St-Germain J, Algouneh A, Mateo F, El Ghamrasni S, Barbour H, Barnes DR, Beesley J, Sanchez O, Berman HK, Brown GW, Affar EB, Chenevix-Trench G, Antoniou AC, Arrowsmith CH, Raught B, Pujana MA, Mekhail K, Hakem A, Hakem R. J Clin Invest. 2021 Feb 1;131(3). pii: 140105. doi: 10.1172/JCI140105. PubMed
Validation of a multicellular tumor microenvironment system for modeling patient tumor biology and drug response. Roller DG, Hoang SA, Rawls KD, Owen KA, Simmers MB, Figler RA, Wulfkuhle JD, Petricoin EF, Wamhoff BR, Gioeli D. Sci Rep. 2021 Mar 10;11(1):5535. doi: 10.1038/s41598-021-84612-z. PubMed
The tumor suppressor kinase DAPK3 drives tumor-intrinsic immunity through the STING-IFN-beta pathway. Takahashi M, Lio CJ, Campeau A, Steger M, Ay F, Mann M, Gonzalez DJ, Jain M, Sharma S. Nat Immunol. 2021 Apr;22(4):485-496. doi: 10.1038/s41590-021-00896-3. Epub 2021 Mar 25. PubMed
Weak humoral immune reactivity among residents of long-term care facilities following one dose of the BNT162b2 mRNA COVID-19 vaccine. Brockman MA, Mwimanzi F, Sang Y, Ng K, Agafitei O, Ennis S, Lapointe H, Young L, Umviligihozo G, Burns L, Brumme C, Leung V, Montaner JSG, Holmes D, DeMarco M, Simons J, Niikura M, Pantophlet R, Romney MG, Brumme ZL. medRxiv. 2021 Mar 24. doi: 10.1101/2021.03.17.21253773. PubMed
m(6)A-independent genome-wide METTL3 and METTL14 redistribution drives the senescence-associated secretory phenotype. Liu P, Li F, Lin J, Fukumoto T, Nacarelli T, Hao X, Kossenkov AV, Simon MC, Zhang R. Nat Cell Biol. 2021 Apr;23(4):355-365. doi: 10.1038/s41556-021-00656-3. Epub 2021 Apr 1. PubMed
Werner Helicase Is a Synthetic-Lethal Vulnerability in Mismatch Repair-Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy, and Immunotherapy. Picco G, Cattaneo CM, van Vliet EJ, Crisafulli G, Rospo G, Consonni S, Vieira SF, Rodriguez IS, Cancelliere C, Banerjee R, Schipper LJ, Oddo D, Dijkstra KK, Cinatl J, Michaelis M, Yang F, Di Nicolantonio F, Sartore-Bianchi A, Siena S, Arena S, Voest EE, Bardelli A, Garnett MJ. Cancer Discov. 2021 Aug;11(8):1923-1937. doi: 10.1158/2159-8290.CD-20-1508. Epub 2021 Apr 9. PubMed
Pharmacological Regulation of Tumor Hypoxia in Model Murine Tumors and Spontaneous Canine Tumors. Benej M, Wu J, Kreamer M, Kery M, Corrales-Guerrero S, Papandreou I, Williams TM, Li Z, Graves EE, Selmic LE, Denko NC. Cancers (Basel). 2021 Apr 3;13(7). pii: cancers13071696. doi: 10.3390/cancers13071696. PubMed
In Vitro Prevascularization of Self-Assembled Human Bone-Like Tissues and Preclinical Assessment Using a Rat Calvarial Bone Defect Model. Kawecki F, Galbraith T, Clafshenkel WP, Fortin M, Auger FA, Fradette J. Materials (Basel). 2021 Apr 17;14(8). pii: ma14082023. doi: 10.3390/ma14082023. PubMed
P32-specific CAR T cells with dual antitumor and antiangiogenic therapeutic potential in gliomas. Rousso-Noori L, Mastandrea I, Talmor S, Waks T, Globerson Levin A, Haugas M, Teesalu T, Alvarez-Vallina L, Eshhar Z, Friedmann-Morvinski D. Nat Commun. 2021 Jun 14;12(1):3615. doi: 10.1038/s41467-021-23817-2. PubMed
A GPC2 antibody-drug conjugate is efficacious against neuroblastoma and small-cell lung cancer via binding a conformational epitope. Raman S, Buongervino SN, Lane MV, Zhelev DV, Zhu Z, Cui H, Martinez B, Martinez D, Wang Y, Upton K, Patel K, Rathi KS, Navia CT, Harmon DB, Li Y, Pawel B, Dimitrov DS, Maris JM, Julien JP, Bosse KR. Cell Rep Med. 2021 Jul 21;2(7):100344. doi: 10.1016/j.xcrm.2021.100344. eCollection 2021 Jul 20. PubMed
Evaluating Humoral Immunity against SARS-CoV-2: Validation of a Plaque-Reduction Neutralization Test and a Multilaboratory Comparison of Conventional and Surrogate Neutralization Assays. Valcourt EJ, Manguiat K, Robinson A, Lin YC, Abe KT, Mubareka S, Shigayeva A, Zhong Z, Girardin RC, DuPuis A, Payne A, McDonough K, Wang Z, Gasser R, Laumaea A, Benlarbi M, Richard J, Prevost J, Anand SP, Dimitrova K, Phillipson C, McGeer A, Gingras AC, Liang C, Petric M, Sekirov I, Morshed M, Finzi A, Drebot M, Wood H. Microbiol Spectr. 2021 Dec 22;9(3):e0088621. doi: 10.1128/Spectrum.00886-21. Epub 2021 Nov 17. PubMed
Synergistic effect of chidamide and venetoclax on apoptosis in acute myeloid leukemia cells and its mechanism. Li G, Li D, Yuan F, Cheng C, Chen L, Wei X. Ann Transl Med. 2021 Oct;9(20):1575. doi: 10.21037/atm-21-5066. PubMed
Phosphate-mediated coanchoring of RBD immunogens and molecular adjuvants to alum potentiates humoral immunity against SARS-CoV-2. Rodrigues KA, Rodriguez-Aponte SA, Dalvie NC, Lee JH, Abraham W, Carnathan DG, Jimenez LE, Ngo JT, Chang JYH, Zhang Z, Yu J, Chang A, Nakao C, Goodwin B, Naranjo CA, Zhang L, Silva M, Barouch DH, Silvestri G, Crotty S, Love JC, Irvine DJ. Sci Adv. 2021 Dec 10;7(50):eabj6538. doi: 10.1126/sciadv.abj6538. Epub 2021 Dec 8. PubMed
Entrectinib-A SARS-CoV-2 Inhibitor in Human Lung Tissue (HLT) Cells. Peralta-Garcia A, Torrens-Fontanals M, Stepniewski TM, Grau-Exposito J, Perea D, Ayinampudi V, Waldhoer M, Zimmermann M, Buzon MJ, Genesca M, Selent J. Int J Mol Sci. 2021 Dec 18;22(24). pii: ijms222413592. doi: 10.3390/ijms222413592. PubMed
3D hanging spheroid plate for high-throughput CAR T cell cytotoxicity assay. Chen Z, Han S, Sanny A, Chan DL, van Noort D, Lim W, Tan AH, Park S. J Nanobiotechnology. 2022 Jan 10;20(1):30. doi: 10.1186/s12951-021-01213-8. PubMed
METTL16 exerts an m(6)A-independent function to facilitate translation and tumorigenesis. Su R, Dong L, Li Y, Gao M, He PC, Liu W, Wei J, Zhao Z, Gao L, Han L, Deng X, Li C, Prince E, Tan B, Qing Y, Qin X, Shen C, Xue M, Zhou K, Chen Z, Xue J, Li W, Qin H, Wu X, Sun M, Nam Y, Chen CW, Huang W, Horne D, Rosen ST, He C, Chen J. Nat Cell Biol. 2022 Feb;24(2):205-216. doi: 10.1038/s41556-021-00835-2. Epub 2022 Feb 10. PubMed
Human inhalable antibody fragments neutralizing SARS-CoV-2 variants for COVID-19 therapy. Minenkova O, Santapaola D, Milazzo FM, Anastasi AM, Battistuzzi G, Chiapparino C, Rosi A, Gritti G, Borleri G, Rambaldi A, Dental C, Viollet C, Pagano B, Salvini L, Marra E, Luberto L, Rossi A, Riccio A, Merlo Pich E, Santoro MG, De Santis R. Mol Ther. 2022 May 4;30(5):1979-1993. doi: 10.1016/j.ymthe.2022.02.013. Epub 2022 Feb 12. PubMed
Impairment of SARS-CoV-2 spike glycoprotein maturation and fusion activity by nitazoxanide: an effect independent of spike variants emergence. Riccio A, Santopolo S, Rossi A, Piacentini S, Rossignol JF, Santoro MG. Cell Mol Life Sci. 2022 Apr 7;79(5):227. doi: 10.1007/s00018-022-04246-w. PubMed
Antibodies induced by an ancestral SARS-CoV-2 strain that cross-neutralize variants from Alpha to Omicron BA.1. Windsor IW, Tong P, Lavidor O, Moghaddam AS, McKay LGA, Gautam A, Chen Y, MacDonald EA, Yoo DK, Griffths A, Wesemann DR, Harrison SC. Sci Immunol. 2022 Aug 12;7(74):eabo3425. doi: 10.1126/sciimmunol.abo3425. Epub 2022 Aug 12. PubMed
RNA N(6) -methyladenosine reader YTHDC1 is essential for TGF-beta-mediated metastasis of triple negative breast cancer. Tan B, Zhou K, Liu W, Prince E, Qing Y, Li Y, Han L, Qin X, Su R, Pokharel SP, Yang L, Zhao Z, Shen C, Li W, Chen Z, Zhang Z, Deng X, Small A, Wang K, Leung K, Chen CW, Shen B, Chen J. Theranostics. 2022 Jul 18;12(13):5727-5743. doi: 10.7150/thno.71872. eCollection 2022. PubMed
Long noncoding RNA LINC00239 inhibits ferroptosis in colorectal cancer by binding to Keap1 to stabilize Nrf2. Han Y, Gao X, Wu N, Jin Y, Zhou H, Wang W, Liu H, Chu Y, Cao J, Jiang M, Yang S, Shi Y, Xie X, Chen F, Han Y, Qin W, Xu B, Liang J. Cell Death Dis. 2022 Aug 29;13(8):742. doi: 10.1038/s41419-022-05192-y. PubMed
A RUNX-targeted gene switch-off approach modulates the BIRC5/PIF1-p21 pathway and reduces glioblastoma growth in mice. Hattori EY, Masuda T, Mineharu Y, Mikami M, Terada Y, Matsui Y, Kubota H, Matsuo H, Hirata M, Kataoka TR, Nakahata T, Ikeda S, Miyamoto S, Sugiyama H, Arakawa Y, Kamikubo Y. Commun Biol. 2022 Sep 9;5(1):939. doi: 10.1038/s42003-022-03917-5. PubMed
Mucosal nanobody IgA as inhalable and affordable prophylactic and therapeutic treatment against SARS-CoV-2 and emerging variants. Li Q, Humphries F, Girardin RC, Wallace A, Ejemel M, Amcheslavsky A, McMahon CT, Schiller ZA, Ma Z, Cruz J, Dupuis AP, Payne AF, Maryam A, Yilmaz NK, McDonough KA, Pierce BG, Schiffer CA, Kruse AC, Klempner MS, Cavacini LA, Fitzgerald KA, Wang Y. Front Immunol. 2022 Sep 12;13:995412. doi: 10.3389/fimmu.2022.995412. eCollection 2022. PubMed
Lipid-laden lung mesenchymal cells foster breast cancer metastasis via metabolic reprogramming of tumor cells and natural killer cells. Gong Z, Li Q, Shi J, Liu ET, Shultz LD, Ren G. Cell Metab. 2022 Dec 6;34(12):1960-1976.e9. doi: 10.1016/j.cmet.2022.11.003. PubMed
A genetically engineered, stem-cell-derived cellular vaccine. Cooper A, Sidaway A, Chandrashekar A, Latta E, Chakraborty K, Yu J, McMahan K, Giffin V, Manickam C, Kroll K, Mosher M, Reeves RK, Gam R, Arthofer E, Choudhry M, Henley T, Barouch DH. Cell Rep Med. 2022 Dec 20;3(12):100843. doi: 10.1016/j.xcrm.2022.100843. Epub 2022 Dec 7. PubMed
EIF4A inhibition targets bioenergetic homeostasis in AML MOLM-14 cells in vitro and in vivo and synergizes with cytarabine and venetoclax. Fooks K, Galicia-Vazquez G, Gife V, Schcolnik-Cabrera A, Nouhi Z, Poon WWL, Luo V, Rys RN, Aloyz R, Orthwein A, Johnson NA, Hulea L, Mercier FE. J Exp Clin Cancer Res. 2022 Dec 9;41(1):340. doi: 10.1186/s13046-022-02542-8. PubMed
METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism. Han L, Dong L, Leung K, Zhao Z, Li Y, Gao L, Chen Z, Xue J, Qing Y, Li W, Pokharel SP, Gao M, Chen M, Shen C, Tan B, Small A, Wang K, Zhang Z, Qin X, Yang L, Wunderlich M, Zhang B, Mulloy JC, Marcucci G, Chen CW, Wei M, Su R, Chen J, Deng X. Cell Stem Cell. 2023 Jan 5;30(1):52-68.e13. doi: 10.1016/j.stem.2022.12.006. PubMed
KDM6A Loss Triggers an Epigenetic Switch That Disrupts Urothelial Differentiation and Drives Cell Proliferation in Bladder Cancer. Qiu H, Makarov V, Bolzenius JK, Halstead A, Parker Y, Wang A, Iyer GV, Wise H, Kim D, Thayaparan V, Lindner DJ, Haber GP, Ting AH, Ren B, Chan TA, Arora V, Solit DB, Lee BH. Cancer Res. 2023 Mar 15;83(6):814-829. doi: 10.1158/0008-5472.CAN-22-1444. PubMed
An Inhibitory Role for Human CD96 Endodomain in T Cell Anti-Tumor Responses. Wang CQ, Choy FC, Sanny A, Murakami T, Tan AH, Lam KP. Cells. 2023 Jan 13;12(2):309. doi: 10.3390/cells12020309. PubMed
Establishment of a neutralization assay for Nipah virus using a high-titer pseudovirus system. Luo X, Wang C, Huang Y, Cong S, Tan J, Hou W, Ma F, Zheng L. Biotechnol Lett. 2023 Apr;45(4):489-498. doi: 10.1007/s10529-023-03351-5. Epub 2023 Jan 21. PubMed
Bone marrow niche chemoprotection of metastatic solid tumors mediated by CYP3A4. Ghiaur G, Valkenburg KC, Esteb C, Ambinder A, Imus PH, Pienta KJ, Jones RJ. Cancer. 2023 Jun 1;129(11):1744-1751. doi: 10.1002/cncr.34704. Epub 2023 Feb 25. PubMed
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