Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

Addgene

EF.hICN1.CMV.GFP Citations (15)

Originally described in: HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding.
Yu X, Alder JK, Chun JH, Friedman AD, Heimfeld S, Cheng L, Civin CI Stem Cells. 2006 Apr . 24(4):876-88.
PubMed Journal

Articles Citing EF.hICN1.CMV.GFP

Articles
p63 regulates human keratinocyte proliferation via MYC-regulated gene network and differentiation commitment through cell adhesion-related gene network. Wu N, Rollin J, Masse I, Lamartine J, Gidrol X. J Biol Chem. 2012 Feb 17;287(8):5627-38. doi: 10.1074/jbc.M111.328120. Epub 2011 Dec 19. PubMed
Cisplatin selects for multidrug-resistant CD133+ cells in lung adenocarcinoma by activating Notch signaling. Liu YP, Yang CJ, Huang MS, Yeh CT, Wu AT, Lee YC, Lai TC, Lee CH, Hsiao YW, Lu J, Shen CN, Lu PJ, Hsiao M. Cancer Res. 2013 Jan 1;73(1):406-16. doi: 10.1158/0008-5472.CAN-12-1733. Epub 2012 Nov 7. PubMed
Specific fate decisions in adult hepatic progenitor cells driven by MET and EGFR signaling. Kitade M, Factor VM, Andersen JB, Tomokuni A, Kaji K, Akita H, Holczbauer A, Seo D, Marquardt JU, Conner EA, Lee SB, Lee YH, Thorgeirsson SS. Genes Dev. 2013 Aug 1;27(15):1706-17. doi: 10.1101/gad.214601.113. PubMed
Notch signaling regulates the differentiation of neural crest from human pluripotent stem cells. Noisa P, Lund C, Kanduri K, Lund R, Lahdesmaki H, Lahesmaa R, Lundin K, Chokechuwattanalert H, Otonkoski T, Tuuri T, Raivio T. J Cell Sci. 2014 May 1;127(Pt 9):2083-94. doi: 10.1242/jcs.145755. Epub 2014 Feb 25. PubMed
Notch pathway targets proangiogenic regulator Sox17 to restrict angiogenesis. Lee SH, Lee S, Yang H, Song S, Kim K, Saunders TL, Yoon JK, Koh GY, Kim I. Circ Res. 2014 Jul 7;115(2):215-26. doi: 10.1161/CIRCRESAHA.115.303142. Epub 2014 Apr 22. PubMed
Ethanol inhibits gamma-secretase proteolytic activity in vascular smooth muscle cells. Hatch E, Morrow D, Liu W, Cahill PA, Redmond EM. Alcohol Clin Exp Res. 2015 Nov;39(11):2115-22. doi: 10.1111/acer.12875. Epub 2015 Oct 7. PubMed
The clerodane diterpene casearin J induces apoptosis of T-ALL cells through SERCA inhibition, oxidative stress, and interference with Notch1 signaling. De Ford C, Heidersdorf B, Haun F, Murillo R, Friedrich T, Borner C, Merfort I. Cell Death Dis. 2016 Jan 28;7:e2070. doi: 10.1038/cddis.2015.413. PubMed
Anti-Tumor Effects of Second Generation beta-Hydroxylase Inhibitors on Cholangiocarcinoma Development and Progression. Huang CK, Iwagami Y, Aihara A, Chung W, de la Monte S, Thomas JM, Olsen M, Carlson R, Yu T, Dong X, Wands J. PLoS One. 2016 Mar 8;11(3):e0150336. doi: 10.1371/journal.pone.0150336. eCollection 2016. PubMed
Decitabine, a DNA-demethylating agent, promotes differentiation via NOTCH1 signaling and alters immune-related pathways in muscle-invasive bladder cancer. Ramakrishnan S, Hu Q, Krishnan N, Wang D, Smit E, Granger V, Rak M, Attwood K, Johnson C, Morrison C, Pili R, Chatta G, Guru K, Gueron G, McNally L, Wang J, Woloszynska-Read A. Cell Death Dis. 2017 Dec 14;8(12):3217. doi: 10.1038/s41419-017-0024-5. PubMed
Notch1 regulates the initiation of metastasis and self-renewal of Group 3 medulloblastoma. Kahn SA, Wang X, Nitta RT, Gholamin S, Theruvath J, Hutter G, Azad TD, Wadi L, Bolin S, Ramaswamy V, Esparza R, Liu KW, Edwards M, Swartling FJ, Sahoo D, Li G, Wechsler-Reya RJ, Reimand J, Cho YJ, Taylor MD, Weissman IL, Mitra SS, Cheshier SH. Nat Commun. 2018 Oct 8;9(1):4121. doi: 10.1038/s41467-018-06564-9. PubMed
Notch3 promotes prostate cancer-induced bone lesion development via MMP-3. Ganguly SS, Hostetter G, Tang L, Frank SB, Saboda K, Mehra R, Wang L, Li X, Keller ET, Miranti CK. Oncogene. 2020 Jan;39(1):204-218. doi: 10.1038/s41388-019-0977-1. Epub 2019 Aug 29. PubMed
Luminescent and fluorescent triple reporter plasmid constructs for Wnt, Hedgehog and Notch pathway. Maier J, Elmenofi S, Taschauer A, Anton M, Sami H, Ogris M. PLoS One. 2019 Dec 20;14(12):e0226570. doi: 10.1371/journal.pone.0226570. eCollection 2019. PubMed

Associated Plasmids

ABL1, Overexpressed in Hepatocellular Carcinomas, Regulates Expression of NOTCH1 and Promotes Development of Liver Tumors in Mice. Wang F, Hou W, Chitsike L, Xu Y, Bettler C, Perera A, Bank T, Cotler SJ, Dhanarajan A, Denning MF, Ding X, Breslin P, Qiang W, Li J, Koleske AJ, Qiu W. Gastroenterology. 2020 Jul;159(1):289-305.e16. doi: 10.1053/j.gastro.2020.03.013. Epub 2020 Jun 24. PubMed
NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation. Miao K, Lei JH, Valecha MV, Zhang A, Xu J, Wang L, Lyu X, Chen S, Miao Z, Zhang X, Su SM, Shao F, Rajendran BK, Bao J, Zeng J, Sun H, Chen P, Tan K, Chen Q, Wong KH, Xu X, Deng CX. Nat Commun. 2020 Jun 26;11(1):3256. doi: 10.1038/s41467-020-16936-9. PubMed
An enhanced triple fluorescence flow-cytometry-based assay shows differential activation of the Notch signaling pathway by human papillomavirus E6 proteins. Lim J, Straub E, Stubenrauch F, Iftner T, Schindler M, Simon C. Sci Rep. 2022 Feb 22;12(1):3000. doi: 10.1038/s41598-022-06922-0. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.