Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

Addgene

pBABE-hygro Citations (25)

Originally described in: Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line.
Morgenstern JP, Land H Nucleic Acids Res. 1990 Jun 25;18(12):3587-96.
PubMed

Articles Citing pBABE-hygro

Articles
ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium. Holland DG, Burleigh A, Git A, Goldgraben MA, Perez-Mancera PA, Chin SF, Hurtado A, Bruna A, Ali HR, Greenwood W, Dunning MJ, Samarajiwa S, Menon S, Rueda OM, Lynch AG, McKinney S, Ellis IO, Eaves CJ, Carroll JS, Curtis C, Aparicio S, Caldas C. EMBO Mol Med. 2011 Mar;3(3):167-80. doi: 10.1002/emmm.201100122. Epub 2011 Feb 18. PubMed
Roles of SATB2 in osteogenic differentiation and bone regeneration. Zhang J, Tu Q, Grosschedl R, Kim MS, Griffin T, Drissi H, Yang P, Chen J. Tissue Eng Part A. 2011 Jul;17(13-14):1767-76. doi: 10.1089/ten.TEA.2010.0503. Epub 2011 Apr 21. PubMed
Oncogenic tyrosine kinases target Dok-1 for ubiquitin-mediated proteasomal degradation to promote cell transformation. Janas JA, Van Aelst L. Mol Cell Biol. 2011 Jul;31(13):2552-65. doi: 10.1128/MCB.05045-11. Epub 2011 May 2. PubMed
Enhanced osseointegration of titanium implant through the local delivery of transcription factor SATB2. Yan SG, Zhang J, Tu QS, Ye JH, Luo E, Schuler M, Kim MS, Griffin T, Zhao J, Duan XJ, Cochran DJ, Murray D, Yang PS, Chen J. Biomaterials. 2011 Nov;32(33):8676-83. doi: 10.1016/j.biomaterials.2011.07.072. Epub 2011 Sep 8. PubMed
The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells. Cordenonsi M, Zanconato F, Azzolin L, Forcato M, Rosato A, Frasson C, Inui M, Montagner M, Parenti AR, Poletti A, Daidone MG, Dupont S, Basso G, Bicciato S, Piccolo S. Cell. 2011 Nov 11;147(4):759-72. doi: 10.1016/j.cell.2011.09.048. PubMed
Tbx6 is a determinant of cardiac and neural cell fate decisions in multipotent P19CL6 cells. Gavrilov S, Nuhrenberg TG, Ashton AW, Peng CF, Moore JC, Konstantinidis K, Mummery CL, Kitsis RN. Differentiation. 2012 Sep;84(2):176-84. doi: 10.1016/j.diff.2012.04.007. Epub 2012 Jun 19. PubMed
A noncatalytic function of the ligation complex during nonhomologous end joining. Cottarel J, Frit P, Bombarde O, Salles B, Negrel A, Bernard S, Jeggo PA, Lieber MR, Modesti M, Calsou P. J Cell Biol. 2013 Jan 21;200(2):173-86. doi: 10.1083/jcb.201203128. PubMed
Lacritin rescues stressed epithelia via rapid forkhead box O3 (FOXO3)-associated autophagy that restores metabolism. Wang N, Zimmerman K, Raab RW, McKown RL, Hutnik CM, Talla V, Tyler MF 4th, Lee JK, Laurie GW. J Biol Chem. 2013 Jun 21;288(25):18146-61. doi: 10.1074/jbc.M112.436584. Epub 2013 May 2. PubMed

Associated Plasmids

A-type lamins maintain the positional stability of DNA damage repair foci in mammalian nuclei. Mahen R, Hattori H, Lee M, Sharma P, Jeyasekharan AD, Venkitaraman AR. PLoS One. 2013 May 2;8(5):e61893. doi: 10.1371/journal.pone.0061893. Print 2013. PubMed
Transcription factor and bone marrow stromal cells in osseointegration of dental implants. Yan SG, Zhang J, Tu Q, Ye JH, Luo E, Schuler M, Dard MM, Yu Y, Murray D, Cochran DL, Kim SH, Yang P, Chen J. Eur Cell Mater. 2013 Dec 19;26:263-70; discussion 270-1. PubMed
A novel mouse model for inhibition of DOHH-mediated hypusine modification reveals a crucial function in embryonic development, proliferation and oncogenic transformation. Sievert H, Pallmann N, Miller KK, Hermans-Borgmeyer I, Venz S, Sendoel A, Preukschas M, Schweizer M, Boettcher S, Janiesch PC, Streichert T, Walther R, Hengartner MO, Manz MG, Brummendorf TH, Bokemeyer C, Braig M, Hauber J, Duncan KE, Balabanov S. Dis Model Mech. 2014 Aug;7(8):963-76. doi: 10.1242/dmm.014449. Epub 2014 May 15. PubMed
ANKS6 is the critical activator of NEK8 kinase in embryonic situs determination and organ patterning. Czarnecki PG, Gabriel GC, Manning DK, Sergeev M, Lemke K, Klena NT, Liu X, Chen Y, Li Y, San Agustin JT, Garnaas MK, Francis RJ, Tobita K, Goessling W, Pazour GJ, Lo CW, Beier DR, Shah JV. Nat Commun. 2015 Jan 20;6:6023. doi: 10.1038/ncomms7023. PubMed
MALT1 is required for EGFR-induced NF-kappaB activation and contributes to EGFR-driven lung cancer progression. Pan D, Jiang C, Ma Z, Blonska M, You MJ, Lin X. Oncogene. 2015 May 18. doi: 10.1038/onc.2015.146. PubMed
AMP-activated Protein Kinase (AMPK) Control of mTORC1 Is p53- and TSC2-independent in Pemetrexed-treated Carcinoma Cells. Agarwal S, Bell CM, Rothbart SB, Moran RG. J Biol Chem. 2015 Nov 13;290(46):27473-86. doi: 10.1074/jbc.M115.665133. Epub 2015 Sep 21. PubMed
Oncogenic RAS-induced downregulation of ATG12 is required for survival of malignant intestinal epithelial cells. Yoo BH, Khan IA, Koomson A, Gowda P, Sasazuki T, Shirasawa S, Gujar S, Rosen KV. Autophagy. 2018;14(1):134-151. doi: 10.1080/15548627.2017.1370171. Epub 2017 Dec 21. PubMed
ARID1A suppresses malignant transformation of human pancreatic cells via mediating senescence-associated miR-503/CDKN2A regulatory axis. Li ZY, Zhu SS, Chen XJ, Zhu J, Chen Q, Zhang YQ, Zhang CL, Guo TT, Zhang LM. Biochem Biophys Res Commun. 2017 Nov 18;493(2):1018-1025. doi: 10.1016/j.bbrc.2017.09.099. Epub 2017 Sep 20. PubMed
Systematic analysis of ATG13 domain requirements for autophagy induction. Wallot-Hieke N, Verma N, Schlutermann D, Berleth N, Deitersen J, Bohler P, Stuhldreier F, Wu W, Seggewiss S, Peter C, Gohlke H, Mizushima N, Stork B. Autophagy. 2018 Mar 21:1-21. doi: 10.1080/15548627.2017.1387342. PubMed
CRISPR/Cas9-mediated knockout of HBsAg inhibits proliferation and tumorigenicity of HBV-positive hepatocellular carcinoma cells. Song J, Zhang X, Ge Q, Yuan C, Chu L, Liang HF, Liao Z, Liu Q, Zhang Z, Zhang B. J Cell Biochem. 2018 Nov;119(10):8419-8431. doi: 10.1002/jcb.27050. Epub 2018 Jun 15. PubMed
Inhibitor of Differentiation-1 Sustains Mutant KRAS-Driven Progression, Maintenance, and Metastasis of Lung Adenocarcinoma via Regulation of a FOSL1 Network. Roman M, Lopez I, Guruceaga E, Baraibar I, Ecay M, Collantes M, Nadal E, Vallejo A, Cadenas S, Miguel ME, Jang JH, Martin-Uriz PS, Castro-Labrador L, Vilas-Zornoza A, Lara-Astiaso D, Ponz-Sarvise M, Rolfo C, Santos ES, Raez LE, Taverna S, Behrens C, Weder W, Wistuba II, Vicent S, Gil-Bazo I. Cancer Res. 2019 Feb 1;79(3):625-638. doi: 10.1158/0008-5472.CAN-18-1479. Epub 2018 Dec 18. PubMed
14-3-3zeta inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling. Song J, Zhang X, Liao Z, Liang H, Chu L, Dong W, Zhang X, Ge Q, Liu Q, Fan P, Zhang Z, Zhang B. J Exp Clin Cancer Res. 2019 Jan 3;38(1):3. doi: 10.1186/s13046-018-1007-9. PubMed
Identification of a mitofusin specificity region that confers unique activities to Mfn1 and Mfn2. Sloat SR, Whitley BN, Engelhart EA, Hoppins S. Mol Biol Cell. 2019 Aug 1;30(17):2309-2319. doi: 10.1091/mbc.E19-05-0291. Epub 2019 Jun 12. PubMed
Insulin-induced serine 22 phosphorylation of retinoid X receptor alpha is dispensable for adipogenesis in brown adipocytes. Ardenkjaer-Larsen J, Rupar K, Sinkeviciute G, Petersen PSS, Villarroel J, Lundh M, Barres R, Rabiee A, Emanuelli B. Adipocyte. 2020 Dec;9(1):142-152. doi: 10.1080/21623945.2020.1747352. PubMed
Laser Micro-Irradiation to Study DNA Recruitment During S Phase. Miwatani-Minter B, Rona G. J Vis Exp. 2021 Apr 16;(170). doi: 10.3791/62466. PubMed
Secretory autophagy maintains proteostasis upon lysosome inhibition. Solvik TA, Nguyen TA, Tony Lin YH, Marsh T, Huang EJ, Wiita AP, Debnath J, Leidal AM. J Cell Biol. 2022 Jun 6;221(6). pii: 213172. doi: 10.1083/jcb.202110151. Epub 2022 Apr 21. PubMed
CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance. Takasugi M, Ohtani N, Takemura K, Emmrich S, Zakusilo FT, Yoshida Y, Kutsukake N, Mariani JN, Windrem MS, Chandler-Militello D, Goldman SA, Satoh J, Ito S, Seluanov A, Gorbunova V. Cell Rep. 2023 Sep 26;42(9):113130. doi: 10.1016/j.celrep.2023.113130. Epub 2023 Sep 13. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.