Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

Addgene

MSCV-XZ066-EGFRvIII Citations (14)

Originally described in: EGFRvIII expression and PTEN loss synergistically induce chromosomal instability and glial tumors.
Li L, Dutra A, Pak E, Labrie JE, Gerstein RM, Pandolfi PP, Recht LD, Ross AH Neuro Oncol. 2009 Feb . 11(1):9-21.
PubMed Journal

Articles Citing MSCV-XZ066-EGFRvIII

Articles
AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer. Cross DA, Ashton SE, Ghiorghiu S, Eberlein C, Nebhan CA, Spitzler PJ, Orme JP, Finlay MR, Ward RA, Mellor MJ, Hughes G, Rahi A, Jacobs VN, Red Brewer M, Ichihara E, Sun J, Jin H, Ballard P, Al-Kadhimi K, Rowlinson R, Klinowska T, Richmond GH, Cantarini M, Kim DW, Ranson MR, Pao W. Cancer Discov. 2014 Sep;4(9):1046-61. doi: 10.1158/2159-8290.CD-14-0337. Epub 2014 Jun 3. PubMed
InsR/IGF1R Pathway Mediates Resistance to EGFR Inhibitors in Glioblastoma. Ma Y, Tang N, Thompson RC, Mobley BC, Clark SW, Sarkaria JN, Wang J. Clin Cancer Res. 2015 Nov 11. PubMed
A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. Mayrhofer M, Gourain V, Reischl M, Affaticati P, Jenett A, Joly JS, Benelli M, Demichelis F, Poliani PL, Sieger D, Mione M. Dis Model Mech. 2017 Jan 1;10(1):15-28. doi: 10.1242/dmm.026500. Epub 2016 Nov 24. PubMed
RANK and EGFR in invasive breast carcinoma. Papanastasiou AD, Sirinian C, Plakoula E, Zolota V, Zarkadis IK, Kalofonos HP. Cancer Genet. 2017 Oct;216-217:61-66. doi: 10.1016/j.cancergen.2017.07.004. Epub 2017 Jul 26. PubMed
RANK-c attenuates aggressive properties of ER-negative breast cancer by inhibiting NF-kappaB activation and EGFR signaling. Sirinian C, Papanastasiou AD, Schizas M, Spella M, Stathopoulos GT, Repanti M, Zarkadis IK, King TA, Kalofonos HP. Oncogene. 2018 Sep;37(37):5101-5114. doi: 10.1038/s41388-018-0324-y. Epub 2018 May 29. PubMed
Direct visualization of single-molecule membrane protein interactions in living cells. Kim DH, Park S, Kim DK, Jeong MG, Noh J, Kwon Y, Zhou K, Lee NK, Ryu SH. PLoS Biol. 2018 Dec 13;16(12):e2006660. doi: 10.1371/journal.pbio.2006660. eCollection 2018 Dec. PubMed
A microbial-based cancer vaccine for induction of EGFRvIII-specific CD8+ T cells and anti-tumor immunity. Zebertavage L, Bambina S, Shugart J, Alice A, Zens KD, Lauer P, Hanson B, Gough MJ, Crittenden MR, Bahjat KS. PLoS One. 2019 Jan 2;14(1):e0209153. doi: 10.1371/journal.pone.0209153. eCollection 2019. PubMed
Chimeric antigen receptor T cell targeting EGFRvIII for metastatic lung cancer therapy. Zhang Z, Jiang J, Wu X, Zhang M, Luo D, Zhang R, Li S, He Y, Bian H, Chen Z. Front Med. 2019 Feb;13(1):57-68. doi: 10.1007/s11684-019-0683-y. Epub 2019 Feb 5. PubMed
Targeting of early endosomes by autophagy facilitates EGFR recycling and signalling. Fraser J, Simpson J, Fontana R, Kishi-Itakura C, Ktistakis NT, Gammoh N. EMBO Rep. 2019 Oct 4;20(10):e47734. doi: 10.15252/embr.201947734. Epub 2019 Aug 26. PubMed
Thyroid receptor-interacting protein 13 and EGFR form a feedforward loop promoting glioblastoma growth. Hu L, Shen D, Liang D, Shi J, Song C, Jiang K, Menglin Ren, Du S, Cheng W, Ma J, Li S, Bi X, Barr MP, Fang Z, Xu Q, Li W, Piao H, Meng S. Cancer Lett. 2020 Nov 28;493:156-166. doi: 10.1016/j.canlet.2020.08.023. Epub 2020 Aug 27. PubMed
BEBT-109, a pan-mutant-selective EGFR inhibitor with potent antitumor activity in EGFR-mutant non-small cell lung cancer. Fan F, Zhou M, Ye X, Mo Z, Ma Y, Luo L, Liang X, Liu H, Weng Y, Lin M, Liu X, Cai X, Qian C. Transl Oncol. 2021 Feb;14(2):100961. doi: 10.1016/j.tranon.2020.100961. Epub 2020 Dec 13. PubMed
EGFR Activates a TAZ-Driven Oncogenic Program in Glioblastoma. Gao M, Fu Y, Zhou W, Gui G, Lal B, Li Y, Xia S, Ji H, Eberhart CG, Laterra J, Ying M. Cancer Res. 2021 Jul 1;81(13):3580-3592. doi: 10.1158/0008-5472.CAN-20-2773. Epub 2021 Apr 28. PubMed
Application of the antitussive agents oxelaidin and butamirate as anti-glioma agents. Lee SJ, Yeom SY, Lee JY, Park C. Sci Rep. 2021 May 12;11(1):10145. doi: 10.1038/s41598-021-89238-9. PubMed
Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening. Ramos A, Koch CE, Liu-Lupo Y, Hellinger RD, Kyung T, Abbott KL, Frose J, Goulet D, Gordon KS, Eidell KP, Leclerc P, Whittaker CA, Larson RC, Muscato AJ, Yates KB, Dubrot J, Doench JG, Regev A, Vander Heiden MG, Maus MV, Manguso RT, Birnbaum ME, Hemann MT. Nat Commun. 2023 Dec 5;14(1):8048. doi: 10.1038/s41467-023-43790-2. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.