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pmRFP-LC3 Citations (54)

Plasmid Article: Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3.
Kimura S, Noda T, Yoshimori T Autophagy. . 3(5):452-60.

Articles Citing pmRFP-LC3

Cathepsin B facilitates autophagy-mediated apoptosis in SPARC overexpressed primitive neuroectodermal tumor cells. Bhoopathi P, Chetty C, Gujrati M, Dinh DH, Rao JS, Lakka S. Cell Death Differ. 2010 Oct;17(10):1529-39. doi: 10.1038/cdd.2010.28. Epub 2010 Mar 26. PubMed
Human-IAPP disrupts the autophagy/lysosomal pathway in pancreatic beta-cells: protective role of p62-positive cytoplasmic inclusions. Rivera JF, Gurlo T, Daval M, Huang CJ, Matveyenko AV, Butler PC, Costes S. Cell Death Differ. 2011 Mar;18(3):415-26. doi: 10.1038/cdd.2010.111. Epub 2010 Sep 3. PubMed
Disrupted in Schizophrenia 1 forms pathological aggresomes that disrupt its function in intracellular transport. Atkin TA, Brandon NJ, Kittler JT. Hum Mol Genet. 2012 May 1;21(9):2017-28. doi: 10.1093/hmg/dds018. Epub 2012 Jan 30. PubMed
Autophagic clearance of Sin Nombre hantavirus glycoprotein Gn promotes virus replication in cells. Hussein IT, Cheng E, Ganaie SS, Werle MJ, Sheema S, Haque A, Mir MA. J Virol. 2012 Jul;86(14):7520-9. doi: 10.1128/JVI.07204-11. Epub 2012 May 2. PubMed
Hyperstimulation of macropinocytosis leads to lysosomal dysfunction during exposure to methamphetamine in SH-SY5Y cells. Nara A, Aki T, Funakoshi T, Unuma K, Uemura K. Brain Res. 2012 Jul 23;1466:1-14. doi: 10.1016/j.brainres.2012.05.017. Epub 2012 May 14. PubMed
Lysosome vacuolation disrupts the completion of autophagy during norephedrine exposure in SH-SY5Y human neuroblastoma cells. Funakoshi T, Aki T, Unuma K, Uemura K. Brain Res. 2013 Jan 15;1490:9-22. doi: 10.1016/j.brainres.2012.10.056. Epub 2012 Nov 2. PubMed
The ubiquitin ligase Mul1 induces mitophagy in skeletal muscle in response to muscle-wasting stimuli. Lokireddy S, Wijesoma IW, Teng S, Bonala S, Gluckman PD, McFarlane C, Sharma M, Kambadur R. Cell Metab. 2012 Nov 7;16(5):613-24. doi: 10.1016/j.cmet.2012.10.005. PubMed
Hypertonic stress promotes autophagy and microtubule-dependent autophagosomal clusters. Nunes P, Ernandez T, Roth I, Qiao X, Strebel D, Bouley R, Charollais A, Ramadori P, Foti M, Meda P, Feraille E, Brown D, Hasler U. Autophagy. 2013 Apr;9(4):550-67. doi: 10.4161/auto.23662. Epub 2013 Feb 4. PubMed
Lewy body-like alpha-synuclein aggregates resist degradation and impair macroautophagy. Tanik SA, Schultheiss CE, Volpicelli-Daley LA, Brunden KR, Lee VM. J Biol Chem. 2013 May 24;288(21):15194-210. doi: 10.1074/jbc.M113.457408. Epub 2013 Mar 26. PubMed
Human placental trophoblasts confer viral resistance to recipient cells. Delorme-Axford E, Donker RB, Mouillet JF, Chu T, Bayer A, Ouyang Y, Wang T, Stolz DB, Sarkar SN, Morelli AE, Sadovsky Y, Coyne CB. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):12048-53. doi: 10.1073/pnas.1304718110. Epub 2013 Jul 1. PubMed
Autophagy mediates avian influenza H5N1 pseudotyped particle-induced lung inflammation through NF-kappaB and p38 MAPK signaling pathways. Pan H, Zhang Y, Luo Z, Li P, Liu L, Wang C, Wang H, Li H, Ma Y. Am J Physiol Lung Cell Mol Physiol. 2014 Jan;306(2):L183-95. doi: 10.1152/ajplung.00147.2013. Epub 2013 Nov 15. PubMed
Autophagy proteins stabilize pathogen-containing phagosomes for prolonged MHC II antigen processing. Romao S, Gasser N, Becker AC, Guhl B, Bajagic M, Vanoaica D, Ziegler U, Roesler J, Dengjel J, Reichenbach J, Munz C. J Cell Biol. 2013 Dec 9;203(5):757-66. doi: 10.1083/jcb.201308173. PubMed
Visualization of intracellular pathways of engineered baculovirus in mammalian cells. Liu Y, Joo KI, Lei Y, Wang P. Virus Res. 2014 Mar 6;181:81-91. doi: 10.1016/j.virusres.2014.01.006. Epub 2014 Jan 20. PubMed
Identification of a post-translationally myristoylated autophagy-inducing domain released by caspase cleavage of huntingtin. Martin DD, Heit RJ, Yap MC, Davidson MW, Hayden MR, Berthiaume LG. Hum Mol Genet. 2014 Jun 15;23(12):3166-79. doi: 10.1093/hmg/ddu027. Epub 2014 Jan 23. PubMed
Dectin-1-dependent LC3 recruitment to phagosomes enhances fungicidal activity in macrophages. Tam JM, Mansour MK, Khan NS, Seward M, Puranam S, Tanne A, Sokolovska A, Becker CE, Acharya M, Baird MA, Choi AM, Davidson MW, Segal BH, Lacy-Hulbert A, Stuart LM, Xavier RJ, Vyas JM. J Infect Dis. 2014 Dec 1;210(11):1844-54. doi: 10.1093/infdis/jiu290. Epub 2014 May 19. PubMed
miR-let-7f-1 regulates SPARC mediated cisplatin resistance in medulloblastoma cells. Pannuru P, Dontula R, Khan AA, Herbert E, Ozer H, Chetty C, Lakka SS. Cell Signal. 2014 Oct;26(10):2193-201. doi: 10.1016/j.cellsig.2014.06.014. Epub 2014 Jul 8. PubMed
Cholesterol-mediated activation of acid sphingomyelinase disrupts autophagy in the retinal pigment epithelium. Toops KA, Tan LX, Jiang Z, Radu RA, Lakkaraju A. Mol Biol Cell. 2015 Jan 1;26(1):1-14. doi: 10.1091/mbc.E14-05-1028. Epub 2014 Nov 5. PubMed
Mutations in the ubiquitin-binding domain of OPTN/optineurin interfere with autophagy-mediated degradation of misfolded proteins by a dominant-negative mechanism. Shen WC, Li HY, Chen GC, Chern Y, Tu PH. Autophagy. 2015 Apr 3;11(4):685-700. doi: 10.4161/auto.36098. PubMed
beta-Cyclodextrin-threaded biocleavable polyrotaxanes ameliorate impaired autophagic flux in Niemann-Pick type C disease. Tamura A, Yui N. J Biol Chem. 2015 Apr 10;290(15):9442-54. doi: 10.1074/jbc.M115.636803. Epub 2015 Feb 24. PubMed
Control of autophagosome axonal retrograde flux by presynaptic activity unveiled using botulinum neurotoxin type a. Wang T, Martin S, Papadopulos A, Harper CB, Mavlyutov TA, Niranjan D, Glass NR, Cooper-White JJ, Sibarita JB, Choquet D, Davletov B, Meunier FA. J Neurosci. 2015 Apr 15;35(15):6179-94. doi: 10.1523/JNEUROSCI.3757-14.2015. PubMed
Protease 3C of hepatitis A virus induces vacuolization of lysosomal/endosomal organelles and caspase-independent cell death. Shubin AV, Demidyuk IV, Lunina NA, Komissarov AA, Roschina MP, Leonova OG, Kostrov SV. BMC Cell Biol. 2015 Feb 27;16:4. doi: 10.1186/s12860-015-0050-z. PubMed
S6K1 controls autophagosome maturation in autophagy induced by sulforaphane or serum deprivation. Hac A, Domachowska A, Narajczyk M, Cyske K, Pawlik A, Herman-Antosiewicz A. Eur J Cell Biol. 2015 Oct;94(10):470-81. doi: 10.1016/j.ejcb.2015.05.001. Epub 2015 May 29. PubMed
KIM-1-/TIM-1-mediated phagocytosis links ATG5-/ULK1-dependent clearance of apoptotic cells to antigen presentation. Brooks CR, Yeung MY, Brooks YS, Chen H, Ichimura T, Henderson JM, Bonventre JV. EMBO J. 2015 Oct 1;34(19):2441-64. doi: 10.15252/embj.201489838. Epub 2015 Aug 17. PubMed
Distinct partitioning of ALS associated TDP-43, FUS and SOD1 mutants into cellular inclusions. Farrawell NE, Lambert-Smith IA, Warraich ST, Blair IP, Saunders DN, Hatters DM, Yerbury JJ. Sci Rep. 2015 Aug 21;5:13416. doi: 10.1038/srep13416. PubMed
Moderate exercise prevents functional remodeling of the anterior pituitary gland in diet-induced insulin resistance in rats: role of oxidative stress and autophagy. Mercau ME, Repetto EM, Perez MN, Martinez Calejman C, Sanchez Puch S, Finkielstein CV, Cymeryng CB. Endocrinology. 2015 Dec 16:en20151777. PubMed
Emodin ameliorates cisplatin-induced apoptosis of rat renal tubular cells in vitro by activating autophagy. Liu H, Gu LB, Tu Y, Hu H, Huang YR, Sun W. Acta Pharmacol Sin. 2016 Jan 18. doi: 10.1038/aps.2015.114. PubMed
Imaging organelle transport in primary hippocampal neurons treated with amyloid-beta oligomers. Gan KJ, Silverman MA. Methods Cell Biol. 2016;131:425-51. doi: 10.1016/bs.mcb.2015.06.012. Epub 2015 Sep 2. PubMed
Tyrosine kinase receptor EGFR regulates the switch in cancer cells between cell survival and cell death induced by autophagy in hypoxia. Chen Y, Henson ES, Xiao W, Huang D, McMillan-Ward EM, Israels SJ, Gibson SB. Autophagy. 2016 Jun 2;12(6):1029-46. doi: 10.1080/15548627.2016.1164357. Epub 2016 May 11. PubMed
Mediation of Autophagic Cell Death by Type 3 Ryanodine Receptor (RyR3) in Adult Hippocampal Neural Stem Cells. Chung KM, Jeong EJ, Park H, An HK, Yu SW. Front Cell Neurosci. 2016 May 6;10:116. doi: 10.3389/fncel.2016.00116. eCollection 2016. PubMed
Identification of TMEM230 mutations in familial Parkinson's disease. Deng HX, Shi Y, Yang Y, Ahmeti KB, Miller N, Huang C, Cheng L, Zhai H, Deng S, Nuytemans K, Corbett NJ, Kim MJ, Deng H, Tang B, Yang Z, Xu Y, Chan P, Huang B, Gao XP, Song Z, Liu Z, Fecto F, Siddique N, Foroud T, Jankovic J, Ghetti B, Nicholson DA, Krainc D, Melen O, Vance JM, Pericak-Vance MA, Ma YC, Rajput AH, Siddique T. Nat Genet. 2016 Jul;48(7):733-9. doi: 10.1038/ng.3589. Epub 2016 Jun 6. PubMed

Associated Plasmids

Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels. Li GB, Fu RQ, Shen HM, Zhou J, Hu XY, Liu YX, Li YN, Zhang HW, Liu X, Zhang YH, Huang C, Zhang R, Gao N. Oncotarget. 2017 Feb 7;8(6):10359-10374. doi: 10.18632/oncotarget.14413. PubMed
GLUT4 Mobilization Supports Energetic Demands of Active Synapses. Ashrafi G, Wu Z, Farrell RJ, Ryan TA. Neuron. 2017 Feb 8;93(3):606-615.e3. doi: 10.1016/j.neuron.2016.12.020. Epub 2017 Jan 19. PubMed
Bassoon Controls Presynaptic Autophagy through Atg5. Okerlund ND, Schneider K, Leal-Ortiz S, Montenegro-Venegas C, Kim SA, Garner LC, Waites CL, Gundelfinger ED, Reimer RJ, Garner CC. Neuron. 2017 Feb 22;93(4):897-913.e7. doi: 10.1016/j.neuron.2017.01.026. PubMed
Shedding of host autophagic proteins from the parasitophorous vacuolar membrane of Plasmodium berghei. Agop-Nersesian C, De Niz M, Niklaus L, Prado M, Eickel N, Heussler VT. Sci Rep. 2017 May 19;7(1):2191. doi: 10.1038/s41598-017-02156-7. PubMed
Protocols for assessing mitophagy in neuronal cell lines and primary neurons. Dagda RK, Rice M. Neuromethods. 2017;123:249-277. doi: 10.1007/978-1-4939-6890-9_13. Epub 2017 Mar 18. PubMed
PKC-eta-MARCKS Signaling Promotes Intracellular Survival of Unopsonized Burkholderia thailandensis. Micheva-Viteva SN, Shou Y, Ganguly K, Wu TH, Hong-Geller E. Front Cell Infect Microbiol. 2017 Jun 7;7:231. doi: 10.3389/fcimb.2017.00231. eCollection 2017. PubMed
A genome-wide CRISPR screen reconciles the role of N-linked glycosylation in galectin-3 transport to the cell surface. Stewart SE, Menzies SA, Popa SJ, Savinykh N, Petrunkina Harrison A, Lehner PJ, Moreau K. J Cell Sci. 2017 Oct 1;130(19):3234-3247. doi: 10.1242/jcs.206425. Epub 2017 Aug 3. PubMed
Inverted recruitment of autophagy proteins to the Plasmodium berghei parasitophorous vacuole membrane. Schmuckli-Maurer J, Reber V, Wacker R, Bindschedler A, Zakher A, Heussler VT. PLoS One. 2017 Aug 25;12(8):e0183797. doi: 10.1371/journal.pone.0183797. eCollection 2017. PubMed
TRIM23 mediates virus-induced autophagy via activation of TBK1. Sparrer KMJ, Gableske S, Zurenski MA, Parker ZM, Full F, Baumgart GJ, Kato J, Pacheco-Rodriguez G, Liang C, Pornillos O, Moss J, Vaughan M, Gack MU. Nat Microbiol. 2017 Nov;2(11):1543-1557. doi: 10.1038/s41564-017-0017-2. Epub 2017 Sep 4. PubMed
Necroptosis promotes autophagy-dependent upregulation of DAMP and results in immunosurveillance. Lin SY, Hsieh SY, Fan YT, Wei WC, Hsiao PW, Tsai DH, Wu TS, Yang NS. Autophagy. 2018;14(5):778-795. doi: 10.1080/15548627.2017.1386359. Epub 2017 Dec 31. PubMed
Acid-Tolerant Monomeric GFP from Olindias formosa. Shinoda H, Ma Y, Nakashima R, Sakurai K, Matsuda T, Nagai T. Cell Chem Biol. 2018 Mar 15;25(3):330-338.e7. doi: 10.1016/j.chembiol.2017.12.005. Epub 2017 Dec 28. PubMed

Associated Plasmids

A novel autophagy inhibitor berbamine blocks SNARE-mediated autophagosome-lysosome fusion through upregulation of BNIP3. Fu R, Deng Q, Zhang H, Hu X, Li Y, Liu Y, Hu J, Luo Q, Zhang Y, Jiang X, Li L, Yang C, Gao N. Cell Death Dis. 2018 Feb 14;9(2):243. doi: 10.1038/s41419-018-0276-8. PubMed
Simultaneous induction and blockade of autophagy by a single agent. Kucharewicz K, Dudkowska M, Zawadzka A, Ogrodnik M, Szczepankiewicz AA, Czarnocki Z, Sikora E. Cell Death Dis. 2018 Mar 2;9(3):353. doi: 10.1038/s41419-018-0383-6. PubMed
Mangiferin enhances endochondral ossification-based bone repair in massive bone defect by inducing autophagy through activating AMP-activated protein kinase signaling pathway. Bai Y, Liu C, Fu L, Gong X, Dou C, Cao Z, Quan H, Li J, Kang F, Dai J, Zhao C, Dong S. FASEB J. 2018 Aug;32(8):4573-4584. doi: 10.1096/fj.201701411R. Epub 2018 Mar 16. PubMed
Proteostasis as a therapeutic target in glomerular injury associated with mutant alpha-actinin-4. Yee A, Papillon J, Guillemette J, Kaufman DR, Kennedy CRJ, Cybulsky AV. Am J Physiol Renal Physiol. 2018 Oct 1;315(4):F954-F966. doi: 10.1152/ajprenal.00082.2018. Epub 2018 Jun 6. PubMed
Cisplatin induces autophagy to enhance hepatitis B virus replication via activation of ROS/JNK and inhibition of the Akt/mTOR pathway. Chen X, Hu Y, Zhang W, Chen K, Hu J, Li X, Liang L, Cai X, Hu J, Wang K, Huang A, Tang N. Free Radic Biol Med. 2019 Feb 1;131:225-236. doi: 10.1016/j.freeradbiomed.2018.12.008. Epub 2018 Dec 11. PubMed
Properties of LINE-1 proteins and repeat element expression in the context of amyotrophic lateral sclerosis. Pereira GC, Sanchez L, Schaughency PM, Rubio-Roldan A, Choi JA, Planet E, Batra R, Turelli P, Trono D, Ostrow LW, Ravits J, Kazazian HH, Wheelan SJ, Heras SR, Mayer J, Garcia-Perez JL, Goodier JL. Mob DNA. 2018 Dec 15;9:35. doi: 10.1186/s13100-018-0138-z. eCollection 2018. PubMed
Nuclear accumulation of UBC9 contributes to SUMOylation of lamin A/C and nucleophagy in response to DNA damage. Li Y, Jiang X, Zhang Y, Gao Z, Liu Y, Hu J, Hu X, Li L, Shi J, Gao N. J Exp Clin Cancer Res. 2019 Feb 11;38(1):67. doi: 10.1186/s13046-019-1048-8. PubMed
Axonal autophagosome maturation defect through failure of ATG9A sorting underpins pathology in AP-4 deficiency syndrome. Ivankovic D, Drew J, Lesept F, White IJ, Lopez Domenech G, Tooze SA, Kittler JT. Autophagy. 2019 May 29:1-17. doi: 10.1080/15548627.2019.1615302. PubMed
A reversible autophagy inhibitor blocks autophagosome-lysosome fusion by preventing Stx17 loading onto autophagosomes. Vats S, Manjithaya R. Mol Biol Cell. 2019 Aug 1;30(17):2283-2295. doi: 10.1091/mbc.E18-08-0482. Epub 2019 Jun 12. PubMed
Autophagic death of neural stem cells mediates chronic stress-induced decline of adult hippocampal neurogenesis and cognitive deficits. Jung S, Choe S, Woo H, Jeong H, An HK, Moon H, Ryu HY, Yeo BK, Lee YW, Choi H, Mun JY, Sun W, Choe HK, Kim EK, Yu SW. Autophagy. 2019 Jun 24:1-19. doi: 10.1080/15548627.2019.1630222. PubMed
Tanycytic TSPO inhibition induces lipophagy to regulate lipid metabolism and improve energy balance. Kim S, Kim N, Park S, Jeon Y, Lee J, Yoo SJ, Lee JW, Moon C, Yu SW, Kim EK. Autophagy. 2019 Aug 30:1-21. doi: 10.1080/15548627.2019.1659616. PubMed
Genetic Ablation of Calcium-independent Phospholipase A2gamma Exacerbates Glomerular Injury in Adriamycin Nephrosis in Mice. Elimam H, Papillon J, Guillemette J, Navarro-Betancourt JR, Cybulsky AV. Sci Rep. 2019 Nov 7;9(1):16229. doi: 10.1038/s41598-019-52834-x. PubMed
HUNK Phosphorylates Rubicon to Support Autophagy. Zambrano JN, Eblen ST, Abt M, Rhett JM, Muise-Helmericks R, Yeh ES. Int J Mol Sci. 2019 Nov 19;20(22). pii: ijms20225813. doi: 10.3390/ijms20225813. PubMed

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