7TGP Citations (31)

Originally described in: Lentiviral vectors to probe and manipulate the wnt signaling pathway.
Fuerer C, Nusse R PLoS One. 2010 . 5(2):e9370. PubMed Journal

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Articles Citing 7TGP

Articles
Insulin inhibits cardiac mesoderm, not mesendoderm, formation during cardiac differentiation of human pluripotent stem cells and modulation of canonical Wnt signaling can rescue this inhibition. Lian X, Zhang J, Zhu K, Kamp TJ, Palecek SP. Stem Cells. 2013 Mar;31(3):447-57. doi: 10.1002/stem.1289. PubMed
WNT5A encodes two isoforms with distinct functions in cancers. Bauer M, Benard J, Gaasterland T, Willert K, Cappellen D. PLoS One. 2013 Nov 18;8(11):e80526. doi: 10.1371/journal.pone.0080526. eCollection 2013. PubMed
Robust Generation of Cardiomyocytes from Human iPS Cells Requires Precise Modulation of BMP and WNT Signaling. Kadari A, Mekala S, Wagner N, Malan D, Koth J, Doll K, Stappert L, Eckert D, Peitz M, Matthes J, Sasse P, Herzig S, Brustle O, Ergun S, Edenhofer F. Stem Cell Rev. 2014 Nov 13. PubMed
Oncogenic signaling in amphiregulin and EGFR-expressing PTEN-null human breast cancer. Kappler CS, Guest ST, Irish JC, Garrett-Mayer E, Kratche Z, Wilson RC, Ethier SP. Mol Oncol. 2015 Feb;9(2):527-43. doi: 10.1016/j.molonc.2014.10.006. Epub 2014 Oct 23. PubMed
A Regulatory Network Involving beta-Catenin, e-Cadherin, PI3k/Akt, and Slug Balances Self-Renewal and Differentiation of Human Pluripotent Stem Cells In Response to Wnt Signaling. Huang TS, Li L, Moalim-Nour L, Jia D, Bai J, Yao Z, Bennett SA, Figeys D, Wang L. Stem Cells. 2015 May;33(5):1419-33. doi: 10.1002/stem.1944. PubMed
Leukemia stem cells in T-ALL require active Hif1alpha and Wnt signaling. Giambra V, Jenkins CE, Lam SH, Hoofd C, Belmonte M, Wang X, Gusscott S, Gracias D, Weng AP. Blood. 2015 Jun 18;125(25):3917-27. doi: 10.1182/blood-2014-10-609370. Epub 2015 May 1. PubMed
LIG4 mediates Wnt signalling-induced radioresistance. Jun S, Jung YS, Suh HN, Wang W, Kim MJ, Oh YS, Lien EM, Shen X, Matsumoto Y, McCrea PD, Li L, Chen J, Park JI. Nat Commun. 2016 Mar 24;7:10994. doi: 10.1038/ncomms10994. PubMed
Pigment epithelium-derived factor restoration increases bone mass and improves bone plasticity in a model of osteogenesis imperfecta type VI via Wnt3a blockade. Belinsky GS, Sreekumar B, Andrejecsk JW, Saltzman WM, Gong J, Herzog RI, Lin S, Horsley V, Carpenter TO, Chung C. FASEB J. 2016 Apr 28. pii: fj.201500027R. PubMed
Activation of Wnt/beta-Catenin in Ewing Sarcoma Cells Antagonizes EWS/ETS Function and Promotes Phenotypic Transition to More Metastatic Cell States. Pedersen EA, Menon R, Bailey KM, Thomas DG, Van Noord RA, Tran J, Wang H, Qu PP, Hoering A, Fearon ER, Chugh R, Lawlor ER. Cancer Res. 2016 Sep 1;76(17):5040-53. doi: 10.1158/0008-5472.CAN-15-3422. Epub 2016 Jun 30. PubMed
Methods to Manipulate and Monitor Wnt Signaling in Human Pluripotent Stem Cells. Huggins IJ, Brafman D, Willert K. Methods Mol Biol. 2016;1481:161-81. doi: 10.1007/978-1-4939-6393-5_16. PubMed
Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling. Lebensohn AM, Dubey R, Neitzel LR, Tacchelly-Benites O, Yang E, Marceau CD, Davis EM, Patel BB, Bahrami-Nejad Z, Travaglini KJ, Ahmed Y, Lee E, Carette JE, Rohatgi R. Elife. 2016 Dec 20;5. doi: 10.7554/eLife.21459. PubMed
Loss of AXIN1 drives acquired resistance to WNT pathway blockade in colorectal cancer cells carrying RSPO3 fusions. Picco G, Petti C, Centonze A, Torchiaro E, Crisafulli G, Novara L, Acquaviva A, Bardelli A, Medico E. EMBO Mol Med. 2017 Mar;9(3):293-303. doi: 10.15252/emmm.201606773. PubMed
A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma. Tammela T, Sanchez-Rivera FJ, Cetinbas NM, Wu K, Joshi NS, Helenius K, Park Y, Azimi R, Kerper NR, Wesselhoeft RA, Gu X, Schmidt L, Cornwall-Brady M, Yilmaz OH, Xue W, Katajisto P, Bhutkar A, Jacks T. Nature. 2017 May 18;545(7654):355-359. doi: 10.1038/nature22334. Epub 2017 May 10. PubMed
Autocrine WNT2 signaling in fibroblasts promotes colorectal cancer progression. Kramer N, Schmollerl J, Unger C, Nivarthi H, Rudisch A, Unterleuthner D, Scherzer M, Riedl A, Artaker M, Crncec I, Lenhardt D, Schwarz T, Prieler B, Han X, Hengstschlager M, Schuler J, Eferl R, Moriggl R, Sommergruber W, Dolznig H. Oncogene. 2017 Sep 28;36(39):5460-5472. doi: 10.1038/onc.2017.144. Epub 2017 May 29. PubMed
An autocrine inflammatory forward-feedback loop after chemotherapy withdrawal facilitates the repopulation of drug-resistant breast cancer cells. Jia D, Li L, Andrew S, Allan D, Li X, Lee J, Ji G, Yao Z, Gadde S, Figeys D, Wang L. Cell Death Dis. 2017 Jul 13;8(7):e2932. doi: 10.1038/cddis.2017.319. PubMed
A simple and scalable hydrogel-based system for culturing protein-producing cells. Li Q, Wang Q, Wang O, Shao K, Lin H, Lei Y. PLoS One. 2018 Jan 2;13(1):e0190364. doi: 10.1371/journal.pone.0190364. eCollection 2018. PubMed
Dual inhibition of Wnt and Yes-associated protein signaling retards the growth of triple-negative breast cancer in both mesenchymal and epithelial states. Sulaiman A, McGarry S, Li L, Jia D, Ooi S, Addison C, Dimitroulakos J, Arnaout A, Nessim C, Yao Z, Ji G, Song H, Gadde S, Li X, Wang L. Mol Oncol. 2018 Apr;12(4):423-440. doi: 10.1002/1878-0261.12167. Epub 2018 Feb 21. PubMed
The Ewing Sarcoma Secretome and Its Response to Activation of Wnt/beta-catenin Signaling. Hawkins AG, Basrur V, da Veiga Leprevost F, Pedersen E, Sperring C, Nesvizhskii AI, Lawlor ER. Mol Cell Proteomics. 2018 May;17(5):901-912. doi: 10.1074/mcp.RA118.000596. Epub 2018 Jan 31. PubMed
MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state. Poli V, Fagnocchi L, Fasciani A, Cherubini A, Mazzoleni S, Ferrillo S, Miluzio A, Gaudioso G, Vaira V, Turdo A, Gaggianesi M, Chinnici A, Lipari E, Bicciato S, Bosari S, Todaro M, Zippo A. Nat Commun. 2018 Mar 9;9(1):1024. doi: 10.1038/s41467-018-03264-2. PubMed
R-spodin2 enhances canonical Wnt signaling to maintain the stemness of glioblastoma cells. Liu S, U KP, Zhang J, Tsang LL, Huang J, Tu SP, Jiang X. Cancer Cell Int. 2018 Oct 11;18:156. doi: 10.1186/s12935-018-0655-3. eCollection 2018. PubMed
FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy. Diaz Osterman CJ, Ozmadenci D, Kleinschmidt EG, Taylor KN, Barrie AM, Jiang S, Bean LM, Sulzmaier FJ, Jean C, Tancioni I, Anderson K, Uryu S, Cordasco EA, Li J, Chen XL, Fu G, Ojalill M, Rappu P, Heino J, Mark AM, Xu G, Fisch KM, Kolev VN, Weaver DT, Pachter JA, Gyorffy B, McHale MT, Connolly DC, Molinolo A, Stupack DG, Schlaepfer DD. Elife. 2019 Sep 3;8. pii: 47327. doi: 10.7554/eLife.47327. PubMed
Cancer-associated fibroblast-derived WNT2 increases tumor angiogenesis in colon cancer. Unterleuthner D, Neuhold P, Schwarz K, Janker L, Neuditschko B, Nivarthi H, Crncec I, Kramer N, Unger C, Hengstschlager M, Eferl R, Moriggl R, Sommergruber W, Gerner C, Dolznig H. Angiogenesis. 2020 May;23(2):159-177. doi: 10.1007/s10456-019-09688-8. Epub 2019 Oct 30. PubMed
Cyclooxygenases Inhibitors Efficiently Induce Cardiomyogenesis in Human Pluripotent Stem Cells. Nemade H, Acharya A, Chaudhari U, Nembo E, Nguemo F, Riet N, Abken H, Hescheler J, Papadopoulos S, Sachinidis A. Cells. 2020 Feb 27;9(3). pii: cells9030554. doi: 10.3390/cells9030554. PubMed
eGFP-tagged Wnt-3a enables functional analysis of Wnt trafficking and signaling and kinetic assessment of Wnt binding to full-length Frizzled. Wesslowski J, Kozielewicz P, Wang X, Cui H, Schihada H, Kranz D, Karuna M P, Levkin P, Gross JC, Boutros M, Schulte G, Davidson G. J Biol Chem. 2020 Jun 26;295(26):8759-8774. doi: 10.1074/jbc.RA120.012892. Epub 2020 May 7. PubMed
Wnt/beta-catenin signaling contributes to prostate cancer heterogeneity through reciprocal suppression of H3K27 trimethylation. Wang F, Zhu Y, Wang F, Wang Y, Dong BJ, Wang N, Gao WQ. Biochem Biophys Res Commun. 2020 Jun 18;527(1):242-249. doi: 10.1016/j.bbrc.2020.04.112. Epub 2020 May 4. PubMed
RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer. Spit M, Fenderico N, Jordens I, Radaszkiewicz T, Lindeboom RG, Bugter JM, Cristobal A, Ootes L, van Osch M, Janssen E, Boonekamp KE, Hanakova K, Potesil D, Zdrahal Z, Boj SF, Medema JP, Bryja V, Koo BK, Vermeulen M, Maurice MM. EMBO J. 2020 Sep 15;39(18):e103932. doi: 10.15252/embj.2019103932. Epub 2020 Aug 10. PubMed
An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma. Zewdu R, Mehrabad EM, Ingram K, Fang P, Gillis KL, Camolotto SA, Orstad G, Jones A, Mendoza MC, Spike BT, Snyder EL. Elife. 2021 Apr 6;10. pii: 66788. doi: 10.7554/eLife.66788. PubMed
Wnt/beta-Catenin Inhibition Disrupts Carboplatin Resistance in Isogenic Models of Triple-Negative Breast Cancer. Abreu de Oliveira WA, Moens S, El Laithy Y, van der Veer BK, Athanasouli P, Cortesi EE, Baietti MF, Koh KP, Ventura JJ, Amant F, Annibali D, Lluis F. Front Oncol. 2021 Jul 22;11:705384. doi: 10.3389/fonc.2021.705384. eCollection 2021. PubMed
Investigation of Colonic Regeneration via Precise Damage Application Using Femtosecond Laser-Based Nanosurgery. Donath S, Angerstein L, Gentemann L, Muller D, Seidler AE, Jesinghaus C, Bleich A, Heisterkamp A, Buettner M, Kalies S. Cells. 2022 Mar 28;11(7). pii: cells11071143. doi: 10.3390/cells11071143. PubMed
R-spondin-3 promotes proliferation and invasion of breast cancer cells independently of Wnt signaling. Ter Steege EJ, Doornbos LW, Haughton PD, van Diest PJ, Hilkens J, Derksen PWB, Bakker ERM. Cancer Lett. 2023 Aug 1;568:216301. doi: 10.1016/j.canlet.2023.216301. Epub 2023 Jul 3. PubMed
Integrative analysis reveals therapeutic potential of pyrvinium pamoate in Merkel cell carcinoma. Yang J, Lim JT, Victor P, Chen C, Khwaja H, Schnellmann RG, Roe DJ, Gokhale PC, DeCaprio JA, Padi M. bioRxiv [Preprint]. 2023 Nov 4:2023.11.01.565218. doi: 10.1101/2023.11.01.565218. PubMed

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