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pCXLE-hUL Citations (85)

Plasmid Article: A more efficient method to generate integration-free human iPS cells.
Okita K, Matsumura Y, Sato Y, Okada A, Morizane A, Okamoto S, Hong H, Nakagawa M, Tanabe K, Tezuka KI, Shibata T, Kunisada T, Takahashi M, Takahashi J, Saji H, Yamanaka S Nat Methods. 2011 Apr 3. ():.
PubMed Journal

Articles Citing pCXLE-hUL

Articles
Conversion of human fibroblasts to angioblast-like progenitor cells. Kurian L, Sancho-Martinez I, Nivet E, Aguirre A, Moon K, Pendaries C, Volle-Challier C, Bono F, Herbert JM, Pulecio J, Xia Y, Li M, Montserrat N, Ruiz S, Dubova I, Rodriguez C, Denli AM, Boscolo FS, Thiagarajan RD, Gage FH, Loring JF, Laurent LC, Izpisua Belmonte JC. Nat Methods. 2013 Jan;10(1):77-83. doi: 10.1038/nmeth.2255. Epub 2012 Dec 2. PubMed
To clone or not to clone? Induced pluripotent stem cells can be generated in bulk culture. Willmann CA, Hemeda H, Pieper LA, Lenz M, Qin J, Joussen S, Sontag S, Wanek P, Denecke B, Schuler HM, Zenke M, Wagner W. PLoS One. 2013 May 29;8(5):e65324. doi: 10.1371/journal.pone.0065324. Print 2013. PubMed
Transcriptome comparison of human neurons generated using induced pluripotent stem cells derived from dental pulp and skin fibroblasts. Chen J, Lin M, Foxe JJ, Pedrosa E, Hrabovsky A, Carroll R, Zheng D, Lachman HM. PLoS One. 2013 Oct 3;8(10):e75682. doi: 10.1371/journal.pone.0075682. eCollection 2013. PubMed
A systematic evaluation of integration free reprogramming methods for deriving clinically relevant patient specific induced pluripotent stem (iPS) cells. Goh PA, Caxaria S, Casper C, Rosales C, Warner TT, Coffey PJ, Nathwani AC. PLoS One. 2013 Nov 26;8(11):e81622. doi: 10.1371/journal.pone.0081622. eCollection 2013. PubMed
Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs. Liu GH, Suzuki K, Li M, Qu J, Montserrat N, Tarantino C, Gu Y, Yi F, Xu X, Zhang W, Ruiz S, Plongthongkum N, Zhang K, Masuda S, Nivet E, Tsunekawa Y, Soligalla RD, Goebl A, Aizawa E, Kim NY, Kim J, Dubova I, Li Y, Ren R, Benner C, del Sol A, Bueren J, Trujillo JP, Surralles J, Cappelli E, Dufour C, Esteban CR, Izpisua Belmonte JC. Nat Commun. 2014 Jul 7;5:4330. doi: 10.1038/ncomms5330. PubMed
Transient p53 suppression increases reprogramming of human fibroblasts without affecting apoptosis and DNA damage. Rasmussen MA, Holst B, Tumer Z, Johnsen MG, Zhou S, Stummann TC, Hyttel P, Clausen C. Stem Cell Reports. 2014 Sep 9;3(3):404-13. doi: 10.1016/j.stemcr.2014.07.006. Epub 2014 Aug 21. PubMed
Translational read-through of the RP2 Arg120stop mutation in patient iPSC-derived retinal pigment epithelium cells. Schwarz N, Carr AJ, Lane A, Moeller F, Chen LL, Aguila M, Nommiste B, Muthiah MN, Kanuga N, Wolfrum U, Nagel-Wolfrum K, da Cruz L, Coffey PJ, Cheetham ME, Hardcastle AJ. Hum Mol Genet. 2015 Feb 15;24(4):972-86. doi: 10.1093/hmg/ddu509. Epub 2014 Oct 6. PubMed
Modelling human development and disease in pluripotent stem-cell-derived gastric organoids. McCracken KW, Cata EM, Crawford CM, Sinagoga KL, Schumacher M, Rockich BE, Tsai YH, Mayhew CN, Spence JR, Zavros Y, Wells JM. Nature. 2014 Dec 18;516(7531):400-4. doi: 10.1038/nature13863. Epub 2014 Oct 29. PubMed
Laser-assisted generation of human induced pluripotent stem cells. Liu Y, Wu D, Lao D, Peterson C, Hohenstein Elliott KA, Snyder EY. Curr Protoc Stem Cell Biol. 2014 Nov 3;31:4A.7.1-4A.7.15. doi: 10.1002/9780470151808.sc04a07s31. PubMed
Efficient iPS cell generation from blood using episomes and HDAC inhibitors. Hubbard JJ, Sullivan SK, Mills JA, Hayes BJ, Torok-Storb BJ, Ramakrishnan A. J Vis Exp. 2014 Oct 28;(92):e52009. doi: 10.3791/52009. PubMed
A comparison of non-integrating reprogramming methods. Schlaeger TM, Daheron L, Brickler TR, Entwisle S, Chan K, Cianci A, DeVine A, Ettenger A, Fitzgerald K, Godfrey M, Gupta D, McPherson J, Malwadkar P, Gupta M, Bell B, Doi A, Jung N, Li X, Lynes MS, Brookes E, Cherry AB, Demirbas D, Tsankov AM, Zon LI, Rubin LL, Feinberg AP, Meissner A, Cowan CA, Daley GQ. Nat Biotechnol. 2015 Jan;33(1):58-63. doi: 10.1038/nbt.3070. Epub 2014 Dec 1. PubMed
Dynamic transcriptional and epigenomic reprogramming from pediatric nasal epithelial cells to induced pluripotent stem cells. Ji H, Zhang X, Oh S, Mayhew CN, Ulm A, Somineni HK, Ericksen M, Wells JM, Khurana Hershey GK. J Allergy Clin Immunol. 2015 Jan;135(1):236-44. doi: 10.1016/j.jaci.2014.08.038. Epub 2014 Oct 14. PubMed
Optimized Generation of Functional Neutrophils and Macrophages from Patient-Specific Induced Pluripotent Stem Cells: Ex Vivo Models of X(0)-Linked, AR22(0)- and AR47(0)- Chronic Granulomatous Diseases. Brault J, Goutagny E, Telugu N, Shao K, Baquie M, Satre V, Coutton C, Grunwald D, Brion JP, Barlogis V, Stephan JL, Plantaz D, Hescheler J, Krause KH, Saric T, Stasia MJ. Biores Open Access. 2014 Dec 1;3(6):311-26. doi: 10.1089/biores.2014.0045. PubMed
A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease. Tidball AM, Bryan MR, Uhouse MA, Kumar KK, Aboud AA, Feist JE, Ess KC, Neely MD, Aschner M, Bowman AB. Hum Mol Genet. 2015 Apr 1;24(7):1929-44. doi: 10.1093/hmg/ddu609. Epub 2014 Dec 8. PubMed
Ultrastructural visualization of the Mesenchymal-to-Epithelial Transition during reprogramming of human fibroblasts to induced pluripotent stem cells. Hoffding MK, Hyttel P. Stem Cell Res. 2015 Jan;14(1):39-53. doi: 10.1016/j.scr.2014.11.003. Epub 2014 Nov 29. PubMed
Modeling Axonal Phenotypes with Human Pluripotent Stem Cells. Denton KR, Xu CC, Li XJ. Methods Mol Biol. 2014 Dec 18. PubMed
Generation of Integration-Free Patient Specific iPS Cells Using Episomal Plasmids Under Feeder Free Conditions. Caxaria S, Arthold S, Nathwani AC, Goh PA. Methods Mol Biol. 2015 Feb 21. PubMed
HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity. Mattis VB, Tom C, Akimov S, Saeedian J, Ostergaard ME, Southwell AL, Doty CN, Ornelas L, Sahabian A, Lenaeus L, Mandefro B, Sareen D, Arjomand J, Hayden MR, Ross CA, Svendsen CN. Hum Mol Genet. 2015 Jun 1;24(11):3257-71. doi: 10.1093/hmg/ddv080. Epub 2015 Mar 3. PubMed
Chromatin fibers are formed by heterogeneous groups of nucleosomes in vivo. Ricci MA, Manzo C, Garcia-Parajo MF, Lakadamyali M, Cosma MP. Cell. 2015 Mar 12;160(6):1145-58. doi: 10.1016/j.cell.2015.01.054. PubMed
Stem cells from human amniotic fluid exert immunoregulatory function via secreted indoleamine 2,3-dioxygenase1. Romani R, Pirisinu I, Calvitti M, Pallotta MT, Gargaro M, Bistoni G, Vacca C, Di Michele A, Orabona C, Rosati J, Pirro M, Giovagnoli S, Matino D, Prontera P, Rosi G, Grohmann U, Talesa VN, Donti E, Puccetti P, Fallarino F. J Cell Mol Med. 2015 Jul;19(7):1593-605. doi: 10.1111/jcmm.12534. Epub 2015 Mar 17. PubMed
An alternative pluripotent state confers interspecies chimaeric competency. Wu J, Okamura D, Li M, Suzuki K, Luo C, Ma L, He Y, Li Z, Benner C, Tamura I, Krause MN, Nery JR, Du T, Zhang Z, Hishida T, Takahashi Y, Aizawa E, Kim NY, Lajara J, Guillen P, Campistol JM, Esteban CR, Ross PJ, Saghatelian A, Ren B, Ecker JR, Izpisua Belmonte JC. Nature. 2015 May 21;521(7552):316-21. doi: 10.1038/nature14413. Epub 2015 May 6. PubMed
Reprogramming LCLs to iPSCs Results in Recovery of Donor-Specific Gene Expression Signature. Thomas SM, Kagan C, Pavlovic BJ, Burnett J, Patterson K, Pritchard JK, Gilad Y. PLoS Genet. 2015 May 7;11(5):e1005216. doi: 10.1371/journal.pgen.1005216. eCollection 2015 May. PubMed
Differentiation of blood T cells: Reprogramming human induced pluripotent stem cells into neuronal cells. Tsai PH, Chang YC, Lee YY, Ko YL, Yang YH, Lin CF, Chang YL, Yu WC, Shih YH, Chen MT. J Chin Med Assoc. 2015 Jun;78(6):353-9. doi: 10.1016/j.jcma.2015.03.007. Epub 2015 May 26. PubMed
Mitochondrial respiratory dysfunction caused by a heteroplasmic mitochondrial DNA mutation blocks cellular reprogramming. Yokota M, Hatakeyama H, Okabe S, Ono Y, Goto Y. Hum Mol Genet. 2015 Aug 15;24(16):4698-709. doi: 10.1093/hmg/ddv201. Epub 2015 May 29. PubMed
A panel of induced pluripotent stem cells from chimpanzees: a resource for comparative functional genomics. Gallego Romero I, Pavlovic BJ, Hernando-Herraez I, Zhou X, Ward MC, Banovich NE, Kagan CL, Burnett JE, Huang CH, Mitrano A, Chavarria CI, Friedrich Ben-Nun I, Li Y, Sabatini K, Leonardo TR, Parast M, Marques-Bonet T, Laurent LC, Loring JF, Gilad Y. Elife. 2015 Jun 23;4:e07103. doi: 10.7554/eLife.07103. PubMed
Transgene-Free Disease-Specific iPSC Generation from Fibroblasts and Peripheral Blood Mononuclear Cells. Fidan K, Ebrahimi A, Caglayan OH, Ozcimen B, Onder TT. Methods Mol Biol. 2016;1353:215-31. doi: 10.1007/7651_2015_278. PubMed
Generation of Induced Pluripotent Stem Cells from Frozen Buffy Coats using Non-integrating Episomal Plasmids. Meraviglia V, Zanon A, Lavdas AA, Schwienbacher C, Silipigni R, Di Segni M, Chen HS, Pramstaller PP, Hicks AA, Rossini A. J Vis Exp. 2015 Jun 5;(100):e52885. doi: 10.3791/52885. PubMed
MicroRNA Profiling of Neurons Generated Using Induced Pluripotent Stem Cells Derived from Patients with Schizophrenia and Schizoaffective Disorder, and 22q11.2 Del. Zhao D, Lin M, Chen J, Pedrosa E, Hrabovsky A, Fourcade HM, Zheng D, Lachman HM. PLoS One. 2015 Jul 14;10(7):e0132387. doi: 10.1371/journal.pone.0132387. eCollection 2015. PubMed
Molecular pathomechanisms and cell-type-specific disease phenotypes of MELAS caused by mutant mitochondrial tRNA(Trp). Hatakeyama H, Katayama A, Komaki H, Nishino I, Goto Y. Acta Neuropathol Commun. 2015 Aug 22;3:52. doi: 10.1186/s40478-015-0227-x. PubMed
Generation of Integration-free Human Induced Pluripotent Stem Cells Using Hair-derived Keratinocytes. Hung SS, Pebay A, Wong RC. J Vis Exp. 2015 Aug 20;(102):e53174. doi: 10.3791/53174. PubMed
A Comparative View on Easy to Deploy non-Integrating Methods for Patient-Specific iPSC Production. Manzini S, Viiri LE, Marttila S, Aalto-Setala K. Stem Cell Rev. 2015 Dec;11(6):900-8. doi: 10.1007/s12015-015-9619-3. PubMed
Practical Integration-Free Episomal Methods for Generating Human Induced Pluripotent Stem Cells. Kime C, Rand TA, Ivey KN, Srivastava D, Yamanaka S, Tomoda K. Curr Protoc Hum Genet. 2015 Oct 6;87:21.2.1-21.2.21. doi: 10.1002/0471142905.hg2102s87. PubMed
Human iPS Cell-Derived Neurons Uncover the Impact of Increased Ras Signaling in Costello Syndrome. Rooney GE, Goodwin AF, Depeille P, Sharir A, Schofield CM, Yeh E, Roose JP, Klein OD, Rauen KA, Weiss LA, Ullian EM. J Neurosci. 2016 Jan 6;36(1):142-52. doi: 10.1523/JNEUROSCI.1547-15.2016. PubMed
C9orf72 promoter hypermethylation is reduced while hydroxymethylation is acquired during reprogramming of ALS patient cells. Esanov R, Belle KC, van Blitterswijk M, Belzil VV, Rademakers R, Dickson DW, Petrucelli L, Boylan KB, Dykxhoorn DM, Wuu J, Benatar M, Wahlestedt C, Zeier Z. Exp Neurol. 2016 Mar;277:171-7. doi: 10.1016/j.expneurol.2015.12.022. Epub 2015 Dec 31. PubMed
Overcoming Pluripotent Stem Cell Dependence on the Repair of Endogenous DNA Damage. Chlon TM, Ruiz-Torres S, Maag L, Mayhew CN, Wikenheiser-Brokamp KA, Davies SM, Mehta P, Myers KC, Wells JM, Wells SI. Stem Cell Reports. 2016 Jan 12;6(1):44-54. doi: 10.1016/j.stemcr.2015.12.001. PubMed
Generation of integration-free induced pluripotent stem cells from a patient with Familial Mediterranean Fever (FMF). Fidan K, Kavaklioglu G, Ebrahimi A, Ozlu C, Ay NZ, Ruacan A, Gul A, Onder TT. Stem Cell Res. 2015 Nov;15(3):694-6. doi: 10.1016/j.scr.2015.10.018. Epub 2015 Nov 2. PubMed
Transcriptional Reactivation of OTX2, RX1 and SIX3 during Reprogramming Contributes to the Generation of RPE Cells from Human iPSCs. Li P, Sun X, Ma Z, Liu Y, Jin Y, Ge R, Hao L, Ma Y, Han S, Sun H, Zhang M, Li R, Li T, Shen L. Int J Biol Sci. 2016 Feb 20;12(5):505-17. doi: 10.7150/ijbs.14212. eCollection 2016. PubMed
Multiple Sclerosis Patient-Specific Primary Neurons Differentiated from Urinary Renal Epithelial Cells via Induced Pluripotent Stem Cells. Massa MG, Gisevius B, Hirschberg S, Hinz L, Schmidt M, Gold R, Prochnow N, Haghikia A. PLoS One. 2016 May 9;11(5):e0155274. doi: 10.1371/journal.pone.0155274. eCollection 2016. PubMed
Myocardial commitment from human pluripotent stem cells: Rapid production of human heart grafts. Garreta E, de Onate L, Fernandez-Santos ME, Oria R, Tarantino C, Climent AM, Marco A, Samitier M, Martinez E, Valls-Margarit M, Matesanz R, Taylor DA, Fernandez-Aviles F, Izpisua Belmonte JC, Montserrat N. Biomaterials. 2016 Aug;98:64-78. doi: 10.1016/j.biomaterials.2016.04.003. Epub 2016 Apr 26. PubMed
Concurrent progress of reprogramming and gene correction to overcome therapeutic limitation of mutant ALK2-iPSC. Kim BY, Jeong S, Lee SY, Lee SM, Gweon EJ, Ahn H, Kim J, Chung SK. Exp Mol Med. 2016 Jun 3;48(6):e237. doi: 10.1038/emm.2016.43. PubMed
Induced pluripotent stem cells (iPSCs) derived from a patient with frontotemporal dementia caused by a P301L mutation in microtubule-associated protein tau (MAPT). Rasmussen MA, Hjermind LE, Hasholt LF, Waldemar G, Nielsen JE, Clausen C, Hyttel P, Holst B. Stem Cell Res. 2016 Jan;16(1):70-4. doi: 10.1016/j.scr.2015.12.008. Epub 2015 Dec 12. PubMed
Induced pluripotent stem cells (iPSCs) derived from a patient with frontotemporal dementia caused by a R406W mutation in microtubule-associated protein tau (MAPT). Rasmussen MA, Hjermind LE, Hasholt LF, Waldemar G, Nielsen JE, Clausen C, Hyttel P, Holst B. Stem Cell Res. 2016 Jan;16(1):75-8. doi: 10.1016/j.scr.2015.12.006. Epub 2015 Dec 12. PubMed
Induced pluripotent stem cells (iPSCs) derived from a pre-symptomatic carrier of a R406W mutation in microtubule-associated protein tau (MAPT) causing frontotemporal dementia. Rasmussen MA, Hjermind LE, Hasholt LF, Waldemar G, Nielsen JE, Clausen C, Hyttel P, Holst B. Stem Cell Res. 2016 Jan;16(1):105-9. doi: 10.1016/j.scr.2015.12.012. Epub 2015 Dec 23. PubMed
Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a L150P mutation in PSEN-1. Tubsuwan A, Pires C, Rasmussen MA, Schmid B, Nielsen JE, Hjermind LE, Hall V, Nielsen TT, Waldemar G, Hyttel P, Clausen C, Kitiyanant N, Freude KK, Holst B. Stem Cell Res. 2016 Jan;16(1):110-2. doi: 10.1016/j.scr.2015.12.015. Epub 2015 Dec 28. PubMed
Generation of an isogenic, gene-corrected control cell line of the spinocerebellar ataxia type 2 patient-derived iPSC line H196. Marthaler AG, Schmid B, Tubsuwan A, Poulsen UB, Engelbrecht AF, Mau-Holzmann UA, Hyttel P, Nielsen JE, Nielsen TT, Holst B. Stem Cell Res. 2016 Jan;16(1):162-5. doi: 10.1016/j.scr.2015.12.031. Epub 2016 Jan 3. PubMed
Generation of an isogenic, gene-corrected control cell line of the spinocerebellar ataxia type 2 patient-derived iPSC line H266. Marthaler AG, Tubsuwan A, Schmid B, Poulsen UB, Engelbrecht AF, Mau-Holzmann UA, Hyttel P, Nielsen TT, Nielsen JE, Holst B. Stem Cell Res. 2016 Jan;16(1):202-5. doi: 10.1016/j.scr.2015.12.048. Epub 2016 Jan 15. PubMed
Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying an A79V mutation in PSEN1. Li T, Pires C, Nielsen TT, Waldemar G, Hjermind LE, Nielsen JE, Dinnyes A, Hyttel P, Freude KK. Stem Cell Res. 2016 Mar;16(2):229-32. doi: 10.1016/j.scr.2016.01.002. Epub 2016 Jan 14. PubMed
Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a M146I mutation in PSEN1. Li T, Pires C, Nielsen TT, Waldemar G, Hjermind LE, Nielsen JE, Dinnyes A, Holst B, Hyttel P, Freude KK. Stem Cell Res. 2016 Mar;16(2):334-7. doi: 10.1016/j.scr.2016.01.001. Epub 2016 Jan 14. PubMed
A human pluripotent stem cell model of catecholaminergic polymorphic ventricular tachycardia recapitulates patient-specific drug responses. Preininger MK, Jha R, Maxwell JT, Wu Q, Singh M, Wang B, Dalal A, Mceachin ZT, Rossoll W, Hales CM, Fischbach PS, Wagner MB, Xu C. Dis Model Mech. 2016 Sep 1;9(9):927-39. doi: 10.1242/dmm.026823. Epub 2016 Aug 4. PubMed
Human Urinary Epithelial Cells as a Source of Engraftable Hepatocyte-Like Cells Using Stem Cell Technology. Sauer V, Tchaikovskaya T, Wang X, Li Y, Zhang W, Tar K, Polgar Z, Ding J, Guha C, Fox IJ, Roy-Chowdhury N, Roy-Chowdhury J. Cell Transplant. 2016 Dec 13;25(12):2221-2243. doi: 10.3727/096368916X692014. Epub 2016 Jun 9. PubMed
Generation of a human induced pluripotent stem cell line via CRISPR-Cas9 mediated integration of a site-specific homozygous mutation in CHMP2B. Zhang Y, Schmid B, Nielsen TT, Nielsen JE, Clausen C, Hyttel P, Holst B, Freude KK. Stem Cell Res. 2016 Jun 16;17(1):151-153. doi: 10.1016/j.scr.2016.06.005. PubMed
Modeling and correction of structural variations in patient-derived iPSCs using CRISPR/Cas9. Park CY, Sung JJ, Choi SH, Lee DR, Park IH, Kim DW. Nat Protoc. 2016 Nov;11(11):2154-2169. doi: 10.1038/nprot.2016.129. Epub 2016 Oct 6. PubMed
Derivation of induced pluripotent stem cells from a familial Alzheimer's disease patient carrying the L282F mutation in presenilin 1. Poon A, Li T, Pires C, Nielsen TT, Nielsen JE, Holst B, Dinnyes A, Hyttel P, Freude KK. Stem Cell Res. 2016 Sep 28;17(3):470-473. doi: 10.1016/j.scr.2016.09.016. PubMed
Establishment of SPAST mutant induced pluripotent stem cells (iPSCs) from a hereditary spastic paraplegia (HSP) patient. Hauser S, Erzler M, Theurer Y, Schuster S, Schule R, Schols L. Stem Cell Res. 2016 Sep 26;17(3):485-488. doi: 10.1016/j.scr.2016.09.022. PubMed
Generation of induced pluripotent stem cells derived from a 77-year-old healthy woman as control for age related diseases. Nimsanor N, Jorring I, Rasmussen MA, Clausen C, Mau-Holzmann UA, Bus C, Hoffmann SA, Gasser T, Kluba T, Holst B, Schmid B. Stem Cell Res. 2016 Sep 28;17(3):550-552. doi: 10.1016/j.scr.2016.09.019. PubMed
Induced pluripotent stem cells (iPSCs) derived from a symptomatic carrier of a S305I mutation in the microtubule-associated protein tau (MAPT)-gene causing frontotemporal dementia. Nimsanor N, Jorring I, Rasmussen MA, Clausen C, Mau-Holzmann UA, Kitiyanant N, Nielsen JE, Nielsen TT, Hyttel P, Holst B, Schmid B. Stem Cell Res. 2016 Oct 20;17(3):564-567. doi: 10.1016/j.scr.2016.10.006. PubMed
Plasmid-Based Generation of Induced Neural Stem Cells from Adult Human Fibroblasts. Capetian P, Azmitia L, Pauly MG, Krajka V, Stengel F, Bernhardi EM, Klett M, Meier B, Seibler P, Stanslowsky N, Moser A, Knopp A, Gillessen-Kaesbach G, Nikkhah G, Wegner F, Dobrossy M, Klein C. Front Cell Neurosci. 2016 Oct 24;10:245. eCollection 2016. PubMed
Integrative transcriptome network analysis of iPSC-derived neurons from schizophrenia and schizoaffective disorder patients with 22q11.2 deletion. Lin M, Pedrosa E, Hrabovsky A, Chen J, Puliafito BR, Gilbert SR, Zheng D, Lachman HM. BMC Syst Biol. 2016 Nov 15;10(1):105. PubMed
Generation of a gene-corrected isogenic control cell line from an Alzheimer's disease patient iPSC line carrying a A79V mutation in PSEN1. Pires C, Schmid B, Petraeus C, Poon A, Nimsanor N, Nielsen TT, Waldemar G, Hjermind LE, Nielsen JE, Hyttel P, Freude KK. Stem Cell Res. 2016 Sep;17(2):285-288. doi: 10.1016/j.scr.2016.08.002. Epub 2016 Aug 7. PubMed
Generation of induced pluripotent stem cells (iPSCs) from a hereditary spastic paraplegia patient carrying a homozygous R486C mutation in CYP7B1 (SPG5). Hoflinger P, Theurer Y, Schule R, Schols L, Hauser S. Stem Cell Res. 2016 Sep;17(2):422-425. doi: 10.1016/j.scr.2016.09.013. Epub 2016 Sep 17. PubMed
Generation of optic atrophy 1 patient-derived induced pluripotent stem cells (iPS-OPA1-BEHR) for disease modeling of complex optic atrophy syndromes (Behr syndrome). Hauser S, Schuster S, Theurer Y, Synofzik M, Schols L. Stem Cell Res. 2016 Sep;17(2):426-429. doi: 10.1016/j.scr.2016.09.012. Epub 2016 Sep 17. PubMed
Induced pluripotent stem cells (iPSCs) derived from cerebrotendinous xanthomatosis (CTX) patient's fibroblasts carrying a R395S mutation. Hoflinger P, Hauser S, Theurer Y, Weissenberger S, Wilke C, Schols L. Stem Cell Res. 2016 Sep;17(2):433-436. doi: 10.1016/j.scr.2016.09.010. Epub 2016 Sep 17. PubMed
Generation of induced pluripotent stem cells (iPSCs) from a hereditary spastic paraplegia patient carrying a homozygous Y275X mutation in CYP7B1 (SPG5). Hauser S, Hoflinger P, Theurer Y, Rattay TW, Schols L. Stem Cell Res. 2016 Sep;17(2):437-440. doi: 10.1016/j.scr.2016.09.011. Epub 2016 Sep 18. PubMed
Reductive carboxylation is a major metabolic pathway in the retinal pigment epithelium. Du J, Yanagida A, Knight K, Engel AL, Vo AH, Jankowski C, Sadilek M, Tran VT, Manson MA, Ramakrishnan A, Hurley JB, Chao JR. Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14710-14715. doi: 10.1073/pnas.1604572113. Epub 2016 Dec 1. PubMed
Generation of an isogenic, gene-corrected iPSC line from a symptomatic 59-year-old female patient with frontotemporal dementia caused by an R406W mutation in the microtubule associated protein tau (MAPT) gene. Nimsanor N, Poulsen U, Rasmussen MA, Clausen C, Mau-Holzmann UA, Nielsen JE, Nielsen TT, Hyttel P, Holst B, Schmid B. Stem Cell Res. 2016 Sep 28;17(3):576-579. doi: 10.1016/j.scr.2016.09.020. PubMed
Generation of an iPSC line from a patient with tyrosine hydroxylase (TH) deficiency: TH-1 iPSC. Jung-Klawitter S, Blau N, Sebe A, Ebersold J, Gohring G, Opladen T. Stem Cell Res. 2016 Oct 26;17(3):580-583. doi: 10.1016/j.scr.2016.10.008. PubMed
Generation of an isogenic, gene-corrected iPSC line from a pre-symptomatic 28-year-old woman with an R406W mutation in the microtubule associated protein tau (MAPT) gene. Nimsanor N, Poulsen U, Rasmussen MA, Clausen C, Mau-Holzmann UA, Nielsen JE, Nielsen TT, Hyttel P, Holst B, Schmid B. Stem Cell Res. 2016 Sep 28;17(3):600-602. doi: 10.1016/j.scr.2016.09.024. PubMed
Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis. Ang YS, Rivas RN, Ribeiro AJ, Srivas R, Rivera J, Stone NR, Pratt K, Mohamed TM, Fu JD, Spencer CI, Tippens ND, Li M, Narasimha A, Radzinsky E, Moon-Grady AJ, Yu H, Pruitt BL, Snyder MP, Srivastava D. Cell. 2016 Dec 15;167(7):1734-1749.e22. doi: 10.1016/j.cell.2016.11.033. PubMed
Mitochondrial respiratory dysfunction disturbs neuronal and cardiac lineage commitment of human iPSCs. Yokota M, Hatakeyama H, Ono Y, Kanazawa M, Goto YI. Cell Death Dis. 2017 Jan 12;8(1):e2551. doi: 10.1038/cddis.2016.484. PubMed
Low dose resveratrol ameliorates mitochondrial respiratory dysfunction and enhances cellular reprogramming. Mizuguchi Y, Hatakeyama H, Sueoka K, Tanaka M, Goto YI. Mitochondrion. 2017 May;34:43-48. doi: 10.1016/j.mito.2016.12.006. Epub 2017 Jan 14. PubMed
Reprogramming Methods Do Not Affect Gene Expression Profile of Human Induced Pluripotent Stem Cells. Trevisan M, Desole G, Costanzi G, Lavezzo E, Palu G, Barzon L. Int J Mol Sci. 2017 Jan 20;18(1). pii: E206. doi: 10.3390/ijms18010206. PubMed
Evaluation of porcine stem cell competence for somatic cell nuclear transfer and production of cloned animals. Secher JO, Liu Y, Petkov S, Luo Y, Li D, Hall VJ, Schmidt M, Callesen H, Bentzon JF, Sorensen CB, Freude KK, Hyttel P. Anim Reprod Sci. 2017 Mar;178:40-49. doi: 10.1016/j.anireprosci.2017.01.007. Epub 2017 Jan 19. PubMed
Interspecies Chimerism with Mammalian Pluripotent Stem Cells. Wu J, Platero-Luengo A, Sakurai M, Sugawara A, Gil MA, Yamauchi T, Suzuki K, Bogliotti YS, Cuello C, Morales Valencia M, Okumura D, Luo J, Vilarino M, Parrilla I, Soto DA, Martinez CA, Hishida T, Sanchez-Bautista S, Martinez-Martinez ML, Wang H, Nohalez A, Aizawa E, Martinez-Redondo P, Ocampo A, Reddy P, Roca J, Maga EA, Esteban CR, Berggren WT, Nunez Delicado E, Lajara J, Guillen I, Guillen P, Campistol JM, Martinez EA, Ross PJ, Izpisua Belmonte JC. Cell. 2017 Jan 26;168(3):473-486.e15. doi: 10.1016/j.cell.2016.12.036. PubMed
Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B. Zhang Y, Schmid B, Nikolaisen NK, Rasmussen MA, Aldana BI, Agger M, Calloe K, Stummann TC, Larsen HM, Nielsen TT, Huang J, Xu F, Liu X, Bolund L, Meyer M, Bak LK, Waagepetersen HS, Luo Y, Nielsen JE, Holst B, Clausen C, Hyttel P, Freude KK. Stem Cell Reports. 2017 Mar 14;8(3):648-658. doi: 10.1016/j.stemcr.2017.01.012. Epub 2017 Feb 16. PubMed
Characterization of energy and neurotransmitter metabolism in cortical glutamatergic neurons derived from human induced pluripotent stem cells: A novel approach to study metabolism in human neurons. Aldana BI, Zhang Y, Lihme MF, Bak LK, Nielsen JE, Holst B, Hyttel P, Freude KK, Waagepetersen HS. Neurochem Int. 2017 Jun;106:48-61. doi: 10.1016/j.neuint.2017.02.010. Epub 2017 Feb 24. PubMed
Rescue of the MERTK phagocytic defect in a human iPSC disease model using translational read-through inducing drugs. Ramsden CM, Nommiste B, R Lane A, Carr AF, Powner MB, J K Smart M, Chen LL, Muthiah MN, Webster AR, Moore AT, Cheetham ME, da Cruz L, Coffey PJ. Sci Rep. 2017 Mar 3;7(1):51. doi: 10.1038/s41598-017-00142-7. PubMed
Mutations in valosin-containing protein (VCP) decrease ADP/ATP translocation across the mitochondrial membrane and impair energy metabolism in human neurons. Ludtmann MHR, Arber C, Bartolome F, de Vicente M, Preza E, Carro E, Houlden H, Gandhi S, Wray S, Abramov AY. J Biol Chem. 2017 May 26;292(21):8907-8917. doi: 10.1074/jbc.M116.762898. Epub 2017 Mar 30. PubMed
Establishment of MUi009 - A human induced pluripotent stem cells from a 32year old male with homozygous beta degrees -thalassemia coinherited with heterozygous alpha-thalassemia 2. Wongkummool W, Maneepitasut W, Tong-Ngam P, Tangprasittipap A, Munkongdee T, Boonchuay C, Svasti S, Kitiyanant N, Paiboonsukwong K, Fucharoen S, Tubsuwan A. Stem Cell Res. 2017 Apr;20:80-83. doi: 10.1016/j.scr.2017.02.012. Epub 2017 Mar 7. PubMed
Derivation of the human induced pluripotent stem cell line MUi017-A from a patient with homozygous Hemoglobin Constant Spring. Wongkummool W, Maneepitasut W, Munkongdee T, Tong-Ngam P, Tangprasittipap A, Svasti S, Kitiyanant N, Paiboonsukwong K, Fucharoen S, Tubsuwan A. Stem Cell Res. 2017 Apr;20:84-87. doi: 10.1016/j.scr.2017.02.014. Epub 2017 Mar 7. PubMed
Generation of induced pluripotent stem cells from peripheral blood CD34+ hematopoietic progenitors of a 31year old healthy woman. Tangprasittipap A, Jittorntrum B, Wongkummool W, Kitiyanant N, Tubsuwan A. Stem Cell Res. 2017 Apr;20:91-93. doi: 10.1016/j.scr.2017.02.013. Epub 2017 Mar 7. PubMed
Generation of an induced pluripotent stem cell line from chorionic villi of a Turner syndrome spontaneous abortion. Parveen S, Panicker MM, Gupta PK. Stem Cell Res. 2017 Mar;19:12-16. doi: 10.1016/j.scr.2016.12.016. Epub 2016 Dec 13. PubMed
Mitochondrial replacement in an iPSC model of Leber's hereditary optic neuropathy. Wong RCB, Lim SY, Hung SSC, Jackson S, Khan S, Van Bergen NJ, De Smit E, Liang HH, Kearns LS, Clarke L, Mackey DA, Hewitt AW, Trounce IA, Pebay A. Aging (Albany NY). 2017 Apr;9(4):1341-1350. doi: 10.18632/aging.101231. PubMed
Fluorescent tagged episomals for stoichiometric induced pluripotent stem cell reprogramming. Schmitt CE, Morales BM, Schmitz EMH, Hawkins JS, Lizama CO, Zape JP, Hsiao EC, Zovein AC. Stem Cell Res Ther. 2017 Jun 5;8(1):132. doi: 10.1186/s13287-017-0581-7. PubMed
Differential Sarcomere and Electrophysiological Maturation of Human iPSC-Derived Cardiac Myocytes in Monolayer vs. Aggregation-Based Differentiation Protocols. Jeziorowska D, Fontaine V, Jouve C, Villard E, Dussaud S, Akbar D, Letang V, Cervello P, Itier JM, Pruniaux MP, Hulot JS. Int J Mol Sci. 2017 Jun 1;18(6). pii: E1173. doi: 10.3390/ijms18061173. PubMed
Generation of induced pluripotent stem cell (iPSC) line from a 36-year-old Charcot-Marie-Tooth disease patient with GJB1 mutation (CMTX). Son D, Kang PJ, Yun W, You S. Stem Cell Res. 2017 May;21:9-12. doi: 10.1016/j.scr.2017.03.006. Epub 2017 Mar 15. PubMed

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