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pEGFP-C1-AR Citations (31)

Originally described in: Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone.
Stenoien DL, Cummings CJ, Adams HP, Mancini MG, Patel K, DeMartino GN, Marcelli M, Weigel NL, Mancini MA Hum Mol Genet. 1999 May . 8(5):731-41.
PubMed Journal

Articles Citing pEGFP-C1-AR

Articles
Piperlongumine induces rapid depletion of the androgen receptor in human prostate cancer cells. Golovine KV, Makhov PB, Teper E, Kutikov A, Canter D, Uzzo RG, Kolenko VM. Prostate. 2013 Jan;73(1):23-30. doi: 10.1002/pros.22535. Epub 2012 May 16. PubMed
Regulation of GLUT transporters by flavonoids in androgen-sensitive and -insensitive prostate cancer cells. Gonzalez-Menendez P, Hevia D, Rodriguez-Garcia A, Mayo JC, Sainz RM. Endocrinology. 2014 Sep;155(9):3238-50. doi: 10.1210/en.2014-1260. Epub 2014 Jun 16. PubMed
L1CAM is expressed in triple-negative breast cancers and is inversely correlated with androgen receptor. Doberstein K, Milde-Langosch K, Bretz NP, Schirmer U, Harari A, Witzel I, Ben-Arie A, Hubalek M, Muller-Holzner E, Reinold S, Zeimet AG, Altevogt P, Fogel M. BMC Cancer. 2014 Dec 15;14:958. doi: 10.1186/1471-2407-14-958. PubMed
Relationship between serum response factor and androgen receptor in prostate cancer. Prencipe M, O'Neill A, O'Hurley G, Nguyen LK, Fabre A, Bjartell A, Gallagher WM, Morrissey C, Kay EW, Watson RW. Prostate. 2015 Nov;75(15):1704-17. doi: 10.1002/pros.23051. Epub 2015 Aug 7. PubMed
Downregulation of key regulatory proteins in androgen dependent prostate tumor cells by oncolytic reovirus. Gupta-Saraf P, Meseke T, Miller CL. Virology. 2015 Nov;485:153-61. doi: 10.1016/j.virol.2015.07.007. Epub 2015 Aug 8. PubMed
Molecular cloning of canine co-chaperone small glutamine-rich tetratricopeptide repeat-containing protein alpha (SGTA) and investigation of its ability to suppress androgen receptor signalling in androgen-independent prostate cancer. Kato Y, Ochiai K, Michishita M, Azakami D, Nakahira R, Morimatsu M, Ishiguro-Oonuma T, Yoshikawa Y, Kobayashi M, Bonkobara M, Kobayashi M, Takahashi K, Watanabe M, Omi T. Vet J. 2015 Nov;206(2):143-8. doi: 10.1016/j.tvjl.2015.08.002. Epub 2015 Aug 7. PubMed
Tumor suppressor REIC/DKK-3 and co-chaperone SGTA: Their interaction and roles in the androgen sensitivity. Ochiai K, Morimatsu M, Kato Y, Ishiguro-Oonuma T, Udagawa C, Rungsuriyawiboon O, Azakami D, Michishita M, Ariyoshi Y, Ueki H, Nasu Y, Kumon H, Watanabe M, Omi T. Oncotarget. 2016 Jan 19;7(3):3283-96. doi: 10.18632/oncotarget.6488. PubMed
The canine prostate cancer cell line CHP-1 shows over-expression of the co-chaperone small glutamine-rich tetratricopeptide repeat-containing protein alpha. Azakami D, Nakahira R, Kato Y, Michishita M, Kobayashi M, Onozawa E, Bonkobara M, Kobayashi M, Takahashi K, Watanabe M, Ishioka K, Sako T, Ochiai K, Omi T. Vet Comp Oncol. 2016 Jan 14. doi: 10.1111/vco.12199. PubMed
Intracellular kinetics of the androgen receptor shown by multimodal Image Correlation Spectroscopy (mICS). Chiu CL, Patsch K, Cutrale F, Soundararajan A, Agus DB, Fraser SE, Ruderman D. Sci Rep. 2016 Mar 3;6:22435. doi: 10.1038/srep22435. PubMed
The lncRNA SLNCR1 Mediates Melanoma Invasion through a Conserved SRA1-like Region. Schmidt K, Joyce CE, Buquicchio F, Brown A, Ritz J, Distel RJ, Yoon CH, Novina CD. Cell Rep. 2016 May 31;15(9):2025-37. doi: 10.1016/j.celrep.2016.04.018. Epub 2016 May 19. PubMed

Associated Plasmids

Single cell dynamic phenotyping. Patsch K, Chiu CL, Engeln M, Agus DB, Mallick P, Mumenthaler SM, Ruderman D. Sci Rep. 2016 Oct 6;6:34785. doi: 10.1038/srep34785. PubMed
FUS interacts with nuclear matrix-associated protein SAFB1 as well as Matrin3 to regulate splicing and ligand-mediated transcription. Yamaguchi A, Takanashi K. Sci Rep. 2016 Oct 12;6:35195. doi: 10.1038/srep35195. PubMed
Co-activator candidate interactions for orphan nuclear receptor NR2E1. Corso-Diaz X, de Leeuw CN, Alonso V, Melchers D, Wong BK, Houtman R, Simpson EM. BMC Genomics. 2016 Oct 26;17(1):832. PubMed
Nuclear transportation of exogenous epidermal growth factor receptor and androgen receptor via extracellular vesicles. Read J, Ingram A, Al Saleh HA, Platko K, Gabriel K, Kapoor A, Pinthus J, Majeed F, Qureshi T, Al-Nedawi K. Eur J Cancer. 2017 Jan;70:62-74. doi: 10.1016/j.ejca.2016.10.017. Epub 2016 Nov 22. PubMed
Src promotes castration-recurrent prostate cancer through androgen receptor-dependent canonical and non-canonical transcriptional signatures. Chattopadhyay I, Wang J, Qin M, Gao L, Holtz R, Vessella RL, Leach RW, Gelman IH. Oncotarget. 2017 Feb 7;8(6):10324-10347. doi: 10.18632/oncotarget.14401. PubMed
ETS Related Gene mediated Androgen Receptor Aggregation and Endoplasmic Reticulum Stress in Prostate Cancer Development. Sreenath TL, Macalindong SS, Mikhalkevich N, Sharad S, Mohamed A, Young D, Borbiev T, Xavier C, Gupta R, Jamal M, Babcock K, Tan SH, Nevalainen MT, Dobi A, Petrovics G, Sesterhenn IA, Rosner IL, Bieberich CJ, Nelson P, Vasioukhin V, Srivastava S. Sci Rep. 2017 Apr 24;7(1):1109. doi: 10.1038/s41598-017-01187-4. PubMed
Canine REIC/Dkk-3 interacts with SGTA and restores androgen receptor signalling in androgen-independent prostate cancer cell lines. Kato Y, Ochiai K, Kawakami S, Nakao N, Azakami D, Bonkobara M, Michishita M, Morimatsu M, Watanabe M, Omi T. BMC Vet Res. 2017 Jun 9;13(1):170. doi: 10.1186/s12917-017-1094-4. PubMed
Regulation of Androgen Receptor Activity by Transient Interactions of Its Transactivation Domain with General Transcription Regulators. De Mol E, Szulc E, Di Sanza C, Martinez-Cristobal P, Bertoncini CW, Fenwick RB, Frigole-Vivas M, Masin M, Hunter I, Buzon V, Brun-Heath I, Garcia J, De Fabritiis G, Estebanez-Perpina E, McEwan IJ, Nebreda AR, Salvatella X. Structure. 2018 Jan 2;26(1):145-152.e3. doi: 10.1016/j.str.2017.11.007. Epub 2017 Dec 7. PubMed
Activation of p53 and destabilization of androgen receptor by combinatorial inhibition of MDM2 and MDMX in prostate cancer cells. Chopra H, Khan Z, Contreras J, Wang H, Sedrak A, Zhu Y. Oncotarget. 2017 Dec 15;9(5):6270-6281. doi: 10.18632/oncotarget.23569. eCollection 2018 Jan 19. PubMed
Inhibition of androgen receptor transactivation function by adenovirus type 12 E1A undermines prostate cancer cell survival. Li D, Tian G, Wang J, Zhao LY, Co O, Underill ZC, Mymryk JS, Claessens F, Dehm SM, Daaka Y, Liao D. Prostate. 2018 Nov;78(15):1140-1156. doi: 10.1002/pros.23689. Epub 2018 Jul 15. PubMed
Cancer Mutations of the Tumor Suppressor SPOP Disrupt the Formation of Active, Phase-Separated Compartments. Bouchard JJ, Otero JH, Scott DC, Szulc E, Martin EW, Sabri N, Granata D, Marzahn MR, Lindorff-Larsen K, Salvatella X, Schulman BA, Mittag T. Mol Cell. 2018 Oct 4;72(1):19-36.e8. doi: 10.1016/j.molcel.2018.08.027. Epub 2018 Sep 20. PubMed

Associated Plasmids

Identification of SEPTIN12 as a novel target of the androgen and estrogen receptors in human testicular cells. Kuo PL, Tseng JY, Chen HI, Wu CY, Omar HA, Wang CY, Cheng HY, Hsu CC, Fu TF, Teng YN. Biochimie. 2019 Mar;158:1-9. doi: 10.1016/j.biochi.2018.11.018. Epub 2018 Dec 1. PubMed
Monitoring dynamic cytotoxic chemotherapy response in castration-resistant prostate cancer using plasma cell-free DNA (cfDNA). Patsch K, Matasci N, Soundararajan A, Diaz P, Agus DB, Ruderman D, Gross ME. BMC Res Notes. 2019 May 15;12(1):275. doi: 10.1186/s13104-019-4312-2. PubMed
TRPM8-androgen receptor association within lipid rafts promotes prostate cancer cell migration. Grolez GP, Gordiendko DV, Clarisse M, Hammadi M, Desruelles E, Fromont G, Prevarskaya N, Slomianny C, Gkika D. Cell Death Dis. 2019 Sep 9;10(9):652. doi: 10.1038/s41419-019-1891-8. PubMed
Disordered region of cereblon is required for efficient degradation by proteolysis-targeting chimera. Kim K, Lee DH, Park S, Jo SH, Ku B, Park SG, Park BC, Jeon YU, Ahn S, Kang CH, Hwang D, Chae S, Ha JD, Kim S, Hwang JY, Kim JH. Sci Rep. 2019 Dec 23;9(1):19654. doi: 10.1038/s41598-019-56177-5. PubMed
Targeting the Oncogenic Long Non-coding RNA SLNCR1 by Blocking Its Sequence-Specific Binding to the Androgen Receptor. Schmidt K, Weidmann CA, Hilimire TA, Yee E, Hatfield BM, Schneekloth JS Jr, Weeks KM, Novina CD. Cell Rep. 2020 Jan 14;30(2):541-554.e5. doi: 10.1016/j.celrep.2019.12.011. PubMed
DNAzyme Cleavage of CAG Repeat RNA in Polyglutamine Diseases. Zhang N, Bewick B, Schultz J, Tiwari A, Krencik R, Zhang A, Adachi K, Xia G, Yun K, Sarkar P, Ashizawa T. Neurotherapeutics. 2021 Jun 23. pii: 10.1007/s13311-021-01075-w. doi: 10.1007/s13311-021-01075-w. PubMed
Diptoindonesin G antagonizes AR signaling and enhances the efficacy of antiandrogen therapy in prostate cancer. Mao F, Kong Y, Liu J, Rao X, Li C, Donahue K, Zhang Y, Jones K, Zhang Q, Xu W, Liu X. Prostate. 2022 Jun;82(8):917-932. doi: 10.1002/pros.24336. Epub 2022 Mar 24. PubMed
Androgen conspires with the CD8(+) T cell exhaustion program and contributes to sex bias in cancer. Kwon H, Schafer JM, Song NJ, Kaneko S, Li A, Xiao T, Ma A, Allen C, Das K, Zhou L, Riesenberg B, Chang Y, Weltge P, Velegraki M, Oh DY, Fong L, Ma Q, Sundi D, Chung D, Li X, Li Z. Sci Immunol. 2022 Jul;7(73):eabq2630. doi: 10.1126/sciimmunol.abq2630. Epub 2022 Jul 1. PubMed
The glycoprotein 5 of porcine reproductive and respiratory syndrome virus stimulates mitochondrial ROS to facilitate viral replication. Zhang S, Zeng L, Su B-Q, Yang G-Y, Wang J, Ming S-L, Chu B-B. mBio. 2023 Dec 4;14(6):e0265123. doi: 10.1128/mbio.02651-23. PubMed
Rational optimization of a transcription factor activation domain inhibitor. Basu S, Martinez-Cristobal P, Frigole-Vivas M, Pesarrodona M, Lewis M, Szulc E, Banuelos CA, Sanchez-Zarzalejo C, Bielskute S, Zhu J, Pombo-Garcia K, Garcia-Cabau C, Zodi L, Dockx H, Smak J, Kaur H, Batlle C, Mateos B, Biesaga M, Escobedo A, Bardia L, Verdaguer X, Ruffoni A, Mawji NR, Wang J, Obst JK, Tam T, Brun-Heath I, Ventura S, Meierhofer D, Garcia J, Robustelli P, Stracker TH, Sadar MD, Riera A, Hnisz D, Salvatella X. Nat Struct Mol Biol. 2023 Dec;30(12):1958-1969. doi: 10.1038/s41594-023-01159-5. Epub 2023 Dec 4. PubMed

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