pLenti-PGK-KRAS4B(G12V) Citations (10)
Originally described in: TAK1 Inhibition Promotes Apoptosis in KRAS-Dependent Colon Cancers.Singh A, Sweeney MF, Yu M, Burger A, Greninger P, Benes C, Haber DA, Settleman J Cell. 2012 Feb 17;148(4):639-50. PubMed Journal
Articles Citing pLenti-PGK-KRAS4B(G12V)
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| Mutant p53 expression in fallopian tube epithelium drives cell migration. Quartuccio SM, Karthikeyan S, Eddie SL, Lantvit DD, O hAinmhire E, Modi DA, Wei JJ, Burdette JE. Int J Cancer. 2015 Oct 1;137(7):1528-38. doi: 10.1002/ijc.29528. Epub 2015 Apr 11. PubMed |
| ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation. de Jong PR, Taniguchi K, Harris AR, Bertin S, Takahashi N, Duong J, Campos AD, Powis G, Corr M, Karin M, Raz E. Nat Commun. 2016 May 17;7:11551. doi: 10.1038/ncomms11551. PubMed |
Oncogenic K-Ras upregulates ITGA6 expression via FOSL1 to induce anoikis resistance and synergizes with alphaV-Class integrins to promote EMT.
Zhang K, Myllymaki SM, Gao P, Devarajan R, Kytola V, Nykter M, Wei GH, Manninen A.
Oncogene. 2017 Oct 12;36(41):5681-5694. doi: 10.1038/onc.2017.177. Epub 2017 Jun 12.
PubMed
Associated Plasmids |
| Chronic Cigarette Smoke-Induced Epigenomic Changes Precede Sensitization of Bronchial Epithelial Cells to Single-Step Transformation by KRAS Mutations. Vaz M, Hwang SY, Kagiampakis I, Phallen J, Patil A, O'Hagan HM, Murphy L, Zahnow CA, Gabrielson E, Velculescu VE, Easwaran HP, Baylin SB. Cancer Cell. 2017 Sep 11;32(3):360-376.e6. doi: 10.1016/j.ccell.2017.08.006. PubMed |
| Induced sensitivity to EGFR inhibitors is mediated by palmitoylated cysteine 1025 of EGFR and requires oncogenic Kras. Kharbanda A, Runkle K, Wang W, Witze ES. Biochem Biophys Res Commun. 2017 Nov 4;493(1):213-219. doi: 10.1016/j.bbrc.2017.09.044. Epub 2017 Sep 9. PubMed |
| Blocking EGFR palmitoylation suppresses PI3K signaling and mutant KRAS lung tumorigenesis. Kharbanda A, Walter DM, Gudiel AA, Schek N, Feldser DM, Witze ES. Sci Signal. 2020 Mar 3;13(621). pii: 13/621/eaax2364. doi: 10.1126/scisignal.aax2364. PubMed |
| Reprogramming of Nucleotide Metabolism Mediates Synergy between Epigenetic Therapy and MAP Kinase Inhibition. Shorstova T, Su J, Zhao T, Dahabieh M, Leibovitch M, De Sa Tavares Russo M, Avizonis D, Rajkumar S, Watson IR, Del Rincon SV, Miller WH Jr, Foulkes WD, Witcher M. Mol Cancer Ther. 2021 Jan;20(1):64-75. doi: 10.1158/1535-7163.MCT-20-0259. Epub 2020 Oct 21. PubMed |
| Architectural control of metabolic plasticity in epithelial cancer cells. Al-Masri M, Paliotti K, Tran R, Halaoui R, Lelarge V, Chatterjee S, Wang LT, Moraes C, McCaffrey L. Commun Biol. 2021 Mar 19;4(1):371. doi: 10.1038/s42003-021-01899-4. PubMed |
| Mutant KRAS drives metabolic reprogramming and autophagic flux in premalignant pancreatic cells. Suzuki T, Kishikawa T, Sato T, Takeda N, Sugiura Y, Seimiya T, Sekiba K, Ohno M, Iwata T, Ishibashi R, Otsuka M, Koike K. Cancer Gene Ther. 2021 Apr 8. pii: 10.1038/s41417-021-00326-4. doi: 10.1038/s41417-021-00326-4. PubMed |
| Ras-mediated activation of mTORC2 promotes breast epithelial cell migration and invasion. Collins SE, Wiegand ME, Werner AN, Brown IN, Mundo MI, Swango DJ, Mouneimne G, Charest PG. Mol Biol Cell. 2023 Feb 1;34(2):ar9. doi: 10.1091/mbc.E22-06-0236. Epub 2022 Dec 21. PubMed |
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