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pcDNA3.1 ShhN Citations (11)

Originally described in: Beachy lab unpub
Unpublished

Articles Citing pcDNA3.1 ShhN

Articles
MEKK2 and MEKK3 suppress Hedgehog pathway-dependent medulloblastoma by inhibiting GLI1 function. Lu J, Liu L, Zheng M, Li X, Wu A, Wu Q, Liao C, Zou J, Song H. Oncogene. 2018 Jul;37(28):3864-3878. doi: 10.1038/s41388-018-0249-5. Epub 2018 Apr 17. PubMed
Unexpected Activities in Regulating Ciliation Contribute to Off-target Effects of Targeted Drugs. Kiseleva AA, Korobeynikov VA, Nikonova AS, Zhang P, Makhov P, Deneka AY, Einarson MB, Serebriiskii IG, Liu H, Peterson JR, Golemis EA. Clin Cancer Res. 2019 Jul 1;25(13):4179-4193. doi: 10.1158/1078-0432.CCR-18-3535. Epub 2019 Mar 13. PubMed
Nilotinib, an approved leukemia drug, inhibits smoothened signaling in Hedgehog-dependent medulloblastoma. Chahal KK, Li J, Kufareva I, Parle M, Durden DL, Wechsler-Reya RJ, Chen CC, Abagyan R. PLoS One. 2019 Sep 20;14(9):e0214901. doi: 10.1371/journal.pone.0214901. eCollection 2019. PubMed
The AHR pathway represses TGFbeta-SMAD3 signalling and has a potent tumour suppressive role in SHH medulloblastoma. Saric N, Selby M, Ramaswamy V, Kool M, Stockinger B, Hogstrand C, Williamson D, Marino S, Taylor MD, Clifford SC, Basson MA. Sci Rep. 2020 Jan 10;10(1):148. doi: 10.1038/s41598-019-56876-z. PubMed
Cortical Neural Stem Cell Lineage Progression Is Regulated by Extrinsic Signaling Molecule Sonic Hedgehog. Zhang Y, Liu G, Guo T, Liang XG, Du H, Yang L, Bhaduri A, Li X, Xu Z, Zhang Z, Li Z, He M, Tsyporin J, Kriegstein AR, Rubenstein JL, Yang Z, Chen B. Cell Rep. 2020 Mar 31;30(13):4490-4504.e4. doi: 10.1016/j.celrep.2020.03.027. PubMed
Gene expression dynamic analysis reveals co-activation of Sonic Hedgehog and epidermal growth factor followed by dynamic silencing. Maroufy V, Shah P, Asghari A, Deng N, Le RNU, Ramirez JC, Yaseen A, Zheng WJ, Umetani M, Wu H. Oncotarget. 2020 Apr 14;11(15):1358-1372. doi: 10.18632/oncotarget.27547. eCollection 2020 Apr 14. PubMed
ABT-199 inhibits Hedgehog pathway by acting as a competitive inhibitor of oxysterol, rather as a BH3 mimetic. Wang J, Zhang Y, Huang WJ, Yang J, Tang WG, Huang TM, Tan WF. Acta Pharmacol Sin. 2021 Jun;42(6):1005-1013. doi: 10.1038/s41401-020-00504-4. Epub 2020 Aug 27. PubMed
Saikosaponin B1 and Saikosaponin D inhibit tumor growth in medulloblastoma allograft mice via inhibiting the Hedgehog signaling pathway. Luo J, Wang J, Yang J, Huang W, Liu J, Tan W, Xin H. J Nat Med. 2022 Jun;76(3):584-593. doi: 10.1007/s11418-022-01603-8. Epub 2022 Feb 16. PubMed
TMED2 binding restricts SMO to the ER and Golgi compartments. Di Minin G, Holzner M, Grison A, Dumeau CE, Chan W, Monfort A, Jerome-Majewska LA, Roelink H, Wutz A. PLoS Biol. 2022 Mar 30;20(3):e3001596. doi: 10.1371/journal.pbio.3001596. eCollection 2022 Mar. PubMed
The Highly Potent AhR Agonist Picoberin Modulates Hh-Dependent Osteoblast Differentiation. Flegel J, Shaaban S, Jia ZJ, Schulte B, Lian Y, Krzyzanowski A, Metz M, Schneidewind T, Wesseler F, Flegel A, Reich A, Brause A, Xue G, Zhang M, Dotsch L, Stender ID, Hoffmann JE, Scheel R, Janning P, Rastinejad F, Schade D, Strohmann C, Antonchick AP, Sievers S, Moura-Alves P, Ziegler S, Waldmann H. J Med Chem. 2022 Dec 22;65(24):16268-16289. doi: 10.1021/acs.jmedchem.2c00956. Epub 2022 Dec 2. PubMed
USP1 promotes cholangiocarcinoma progression by deubiquitinating PARP1 to prevent its proteasomal degradation. Zhang DY, Zhu Y, Wu Q, Ma S, Ma Y, Shen ZC, Wang Z, Sun W, Zhou YC, Wang D, Zhou S, Liu Z, Kwong LN, Lu Z. Cell Death Dis. 2023 Oct 11;14(10):669. doi: 10.1038/s41419-023-06172-6. PubMed

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