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pCMV-myc-ERK2-L4A-MEK1_fusion Citations (9)

Originally described in: A constitutively active and nuclear form of the MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformation.
Robinson MJ, Stippec SA, Goldsmith E, White MA, Cobb MH Curr Biol. 1998 Oct 22;8(21):1141-50.
PubMed Journal

Articles Citing pCMV-myc-ERK2-L4A-MEK1_fusion

Articles
Englerin A Inhibits EWS-FLI1 DNA Binding in Ewing Sarcoma Cells. Caropreso V, Darvishi E, Turbyville TJ, Ratnayake R, Grohar PJ, McMahon JB, Woldemichael GM. J Biol Chem. 2016 May 6;291(19):10058-66. doi: 10.1074/jbc.M115.701375. Epub 2016 Mar 9. PubMed
Somatodendritic accumulation of Tau in Alzheimer's disease is promoted by Fyn-mediated local protein translation. Li C, Gotz J. EMBO J. 2017 Nov 2;36(21):3120-3138. doi: 10.15252/embj.201797724. Epub 2017 Sep 1. PubMed
Generation of an OCT4 reporter human induced pluripotent stem cell line using CRISPR/SpCas9. Balboa D, Weltner J, Novik Y, Eurola S, Wartiovaara K, Otonkoski T. Stem Cell Res. 2017 Aug;23:105-108. doi: 10.1016/j.scr.2017.07.006. Epub 2017 Jul 11. PubMed

Associated Plasmids

Targeting CDK1 and MEK/ERK Overcomes Apoptotic Resistance in BRAF-Mutant Human Colorectal Cancer. Zhang P, Kawakami H, Liu W, Zeng X, Strebhardt K, Tao K, Huang S, Sinicrope FA. Mol Cancer Res. 2018 Mar;16(3):378-389. doi: 10.1158/1541-7786.MCR-17-0404. Epub 2017 Dec 12. PubMed
Transforming growth factor-beta downregulates sGC subunit expression in pulmonary artery smooth muscle cells via MEK and ERK signaling. Du L, Roberts JD Jr. Am J Physiol Lung Cell Mol Physiol. 2019 Jan 1;316(1):L20-L34. doi: 10.1152/ajplung.00319.2018. Epub 2018 Sep 27. PubMed
Type VI collagen promotes lung epithelial cell spreading and wound-closure. Mereness JA, Bhattacharya S, Wang Q, Ren Y, Pryhuber GS, Mariani TJ. PLoS One. 2018 Dec 14;13(12):e0209095. doi: 10.1371/journal.pone.0209095. eCollection 2018. PubMed
Therapeutic Targeting of the Secreted Lysophospholipase D Autotaxin Suppresses Tuberous Sclerosis Complex-Associated Tumorigenesis. Feng Y, Mischler WJ, Gurung AC, Kavanagh TR, Androsov G, Sadow PM, Herbert ZT, Priolo C. Cancer Res. 2020 Jul 1;80(13):2751-2763. doi: 10.1158/0008-5472.CAN-19-2884. Epub 2020 May 11. PubMed
ERK signaling mediates resistance to immunomodulatory drugs in the bone marrow microenvironment. Liu J, Hideshima T, Xing L, Wang S, Zhou W, Samur MK, Sewastianik T, Ogiya D, An G, Gao S, Yang L, Ji T, Bianchi G, Wen K, Tai YT, Munshi N, Richardson P, Carrasco R, Cang Y, Anderson KC. Sci Adv. 2021 Jun 4;7(23). pii: 7/23/eabg2697. doi: 10.1126/sciadv.abg2697. Print 2021 Jun. PubMed
ERK phosphorylation disrupts the intramolecular interaction of capicua to promote cytoplasmic translocation of capicua and tumor growth. Park J, Park GY, Lee J, Park J, Kim S, Kim E, Park SY, Yoon JH, Lee Y. Front Mol Biosci. 2022 Dec 22;9:1030725. doi: 10.3389/fmolb.2022.1030725. eCollection 2022. PubMed

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