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p3s-Cas9HC Citations (30)

Originally described in: Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease.
Cho SW, Kim S, Kim JM, Kim JS Nat Biotechnol. 2013 Jan 29. doi: 10.1038/nbt.2507. PubMed Journal

Articles Citing p3s-Cas9HC

Articles
Generation of knockout mice using engineered nucleases. Sung YH, Jin Y, Kim S, Lee HW. Methods. 2014 Aug 15;69(1):85-93. doi: 10.1016/j.ymeth.2014.02.009. Epub 2014 Feb 18. PubMed
Surrogate reporter-based enrichment of cells containing RNA-guided Cas9 nuclease-induced mutations. Ramakrishna S, Cho SW, Kim S, Song M, Gopalappa R, Kim JS, Kim H. Nat Commun. 2014 Feb 26;5:3378. doi: 10.1038/ncomms4378. PubMed
A puromycin selectable cell line for the enrichment of mouse embryonic stem cell-derived V3 interneurons. Xu H, Iyer N, Huettner JE, Sakiyama-Elbert SE. Stem Cell Res Ther. 2015 Nov 10;6:220. doi: 10.1186/s13287-015-0213-z. PubMed
Generation of Highly Enriched V2a Interneurons from Mouse Embryonic Stem Cells. Iyer NR, Huettner JE, Butts JC, Brown CR, Sakiyama-Elbert SE. Exp Neurol. 2016 Jan 16. pii: S0014-4886(16)30009-7. doi: 10.1016/j.expneurol.2016.01.011. PubMed
Genome-wide target specificities of CRISPR RNA-guided programmable deaminases. Kim D, Lim K, Kim ST, Yoon SH, Kim K, Ryu SM, Kim JS. Nat Biotechnol. 2017 May;35(5):475-480. doi: 10.1038/nbt.3852. Epub 2017 Apr 10. PubMed

Associated Plasmids
Sensing Self and Foreign Circular RNAs by Intron Identity. Chen YG, Kim MV, Chen X, Batista PJ, Aoyama S, Wilusz JE, Iwasaki A, Chang HY. Mol Cell. 2017 Jul 20;67(2):228-238.e5. doi: 10.1016/j.molcel.2017.05.022. Epub 2017 Jun 15. PubMed
Fusion guide RNAs for orthogonal gene manipulation with Cas9 and Cpf1. Kweon J, Jang AH, Kim DE, Yang JW, Yoon M, Rim Shin H, Kim JS, Kim Y. Nat Commun. 2017 Nov 23;8(1):1723. doi: 10.1038/s41467-017-01650-w. PubMed
A Survey of Validation Strategies for CRISPR-Cas9 Editing. Sentmanat MF, Peters ST, Florian CP, Connelly JP, Pruett-Miller SM. Sci Rep. 2018 Jan 17;8(1):888. doi: 10.1038/s41598-018-19441-8. PubMed
An "off-the-shelf" fratricide-resistant CAR-T for the treatment of T cell hematologic malignancies. Cooper ML, Choi J, Staser K, Ritchey JK, Devenport JM, Eckardt K, Rettig MP, Wang B, Eissenberg LG, Ghobadi A, Gehrs LN, Prior JL, Achilefu S, Miller CA, Fronick CC, O'Neal J, Gao F, Weinstock DM, Gutierrez A, Fulton RS, DiPersio JF. Leukemia. 2018 Sep;32(9):1970-1983. doi: 10.1038/s41375-018-0065-5. Epub 2018 Feb 20. PubMed
In vitro effects of FBXW7 mutation in serous endometrial cancer: Increased levels of potentially druggable proteins and sensitivity to SI-2 and dinaciclib. Urick ME, Bell DW. Mol Carcinog. 2018 Nov;57(11):1445-1457. doi: 10.1002/mc.22867. Epub 2018 Jul 12. PubMed
Switchable genome editing via genetic code expansion. Suzuki T, Asami M, Patel SG, Luk LYP, Tsai YH, Perry ACF. Sci Rep. 2018 Jul 3;8(1):10051. doi: 10.1038/s41598-018-28178-3. PubMed
Directed evolution of CRISPR-Cas9 to increase its specificity. Lee JK, Jeong E, Lee J, Jung M, Shin E, Kim YH, Lee K, Jung I, Kim D, Kim S, Kim JS. Nat Commun. 2018 Aug 6;9(1):3048. doi: 10.1038/s41467-018-05477-x. PubMed

Associated Plasmids
Muscarinic Acetylcholine Receptors Chrm1 and Chrm3 Are Essential for REM Sleep. Niwa Y, Kanda GN, Yamada RG, Shi S, Sunagawa GA, Ukai-Tadenuma M, Fujishima H, Matsumoto N, Masumoto KH, Nagano M, Kasukawa T, Galloway J, Perrin D, Shigeyoshi Y, Ukai H, Kiyonari H, Sumiyama K, Ueda HR. Cell Rep. 2018 Aug 28;24(9):2231-2247.e7. doi: 10.1016/j.celrep.2018.07.082. PubMed
ULK1 and ULK2 Regulate Stress Granule Disassembly Through Phosphorylation and Activation of VCP/p97. Wang B, Maxwell BA, Joo JH, Gwon Y, Messing J, Mishra A, Shaw TI, Ward AL, Quan H, Sakurada SM, Pruett-Miller SM, Bertorini T, Vogel P, Kim HJ, Peng J, Taylor JP, Kundu M. Mol Cell. 2019 May 16;74(4):742-757.e8. doi: 10.1016/j.molcel.2019.03.027. Epub 2019 Apr 9. PubMed
A substitution mutation in a conserved domain of mammalian acetate-dependent acetyl CoA synthetase 2 results in destabilized protein and impaired HIF-2 signaling. Nagati JS, Xu M, Garcia T, Comerford SA, Hammer RE, Garcia JA. PLoS One. 2019 Nov 14;14(11):e0225105. doi: 10.1371/journal.pone.0225105. eCollection 2019. PubMed
Transcriptional Programming of Human Mechanosensory Neuron Subtypes from Pluripotent Stem Cells. Nickolls AR, Lee MM, Espinoza DF, Szczot M, Lam RM, Wang Q, Beers J, Zou J, Nguyen MQ, Solinski HJ, AlJanahi AA, Johnson KR, Ward ME, Chesler AT, Bonnemann CG. Cell Rep. 2020 Jan 21;30(3):932-946.e7. doi: 10.1016/j.celrep.2019.12.062. PubMed

Associated Plasmids
MYCN amplification and ATRX mutations are incompatible in neuroblastoma. Zeineldin M, Federico S, Chen X, Fan Y, Xu B, Stewart E, Zhou X, Jeon J, Griffiths L, Nguyen R, Norrie J, Easton J, Mulder H, Yergeau D, Liu Y, Wu J, Van Ryn C, Naranjo A, Hogarty MD, Kaminski MM, Valentine M, Pruett-Miller SM, Pappo A, Zhang J, Clay MR, Bahrami A, Vogel P, Lee S, Shelat A, Sarthy JF, Meers MP, George RE, Mardis ER, Wilson RK, Henikoff S, Downing JR, Dyer MA. Nat Commun. 2020 Feb 14;11(1):913. doi: 10.1038/s41467-020-14682-6. PubMed
The histone deacetylase complex MiDAC regulates a neurodevelopmental gene expression program to control neurite outgrowth. Mondal B, Jin H, Kallappagoudar S, Sedkov Y, Martinez T, Sentmanat MF, Poet GJ, Li C, Fan Y, Pruett-Miller SM, Herz HM. Elife. 2020 Apr 16;9. pii: 57519. doi: 10.7554/eLife.57519. PubMed
Telomere Dysfunction Activates p53 and Represses HNF4alpha Expression Leading to Impaired Human Hepatocyte Development and Function. Munroe M, Niero EL, Fok WC, Vessoni AT, Jeong HC, Brenner KA, Batista LFZ. Hepatology. 2020 Jun 9. doi: 10.1002/hep.31414. PubMed
Prediction-based highly sensitive CRISPR off-target validation using target-specific DNA enrichment. Kang SH, Lee WJ, An JH, Lee JH, Kim YH, Kim H, Oh Y, Park YH, Jin YB, Jun BH, Hur JK, Kim SU, Lee SH. Nat Commun. 2020 Jul 17;11(1):3596. doi: 10.1038/s41467-020-17418-8. PubMed
Gene Manipulation Using Fusion Guide RNAs for Cas9 and Cas12a. Shin HR, Kweon J, Kim Y. Methods Mol Biol. 2021;2162:185-193. doi: 10.1007/978-1-0716-0687-2_10. PubMed
High-fidelity reconstitution of stress granules and nucleoli in mammalian cellular lysate. Freibaum BD, Messing J, Yang P, Kim HJ, Taylor JP. J Cell Biol. 2021 Mar 1;220(3). pii: 211726. doi: 10.1083/jcb.202009079. PubMed
SARM1 is required in human derived sensory neurons for injury-induced and neurotoxic axon degeneration. Chen YH, Sasaki Y, DiAntonio A, Milbrandt J. Exp Neurol. 2021 May;339:113636. doi: 10.1016/j.expneurol.2021.113636. Epub 2021 Feb 4. PubMed
AWP1 Restrains the Aggressive Behavior of Breast Cancer Cells Induced by TNF-alpha. Kim EY, Kim JE, Choi B, Kweon J, Park SO, Lee HS, Lee EJ, Oh S, Shin HR, Choi H, Kim Y, Chang EJ. Front Oncol. 2021 Mar 18;11:631469. doi: 10.3389/fonc.2021.631469. eCollection 2021. PubMed
SLFN11 is Widely Expressed in Pediatric Sarcoma and Induces Variable Sensitization to Replicative Stress Caused By DNA-Damaging Agents. Gartrell J, Mellado-Largarde M, Clay MR, Bahrami A, Sahr NA, Sykes A, Blankenship K, Hoffmann L, Xie J, Cho HP, Twarog N, Connelly M, Yan KK, Yu J, Porter SN, Pruett-Miller SM, Neale G, Tinkle CL, Federico SM, Stewart EA, Shelat AA. Mol Cancer Ther. 2021 Nov;20(11):2151-2165. doi: 10.1158/1535-7163.MCT-21-0089. Epub 2021 Aug 19. PubMed
Generation of two induced pluripotent stem cell lines with heterozygous and homozygous GAG deletion in TOR1A gene from a healthy hiPSC line. Akter M, Cui H, Chen YH, Ding B. Stem Cell Res. 2021 Oct;56:102536. doi: 10.1016/j.scr.2021.102536. Epub 2021 Sep 11. PubMed
Ablation of VLA4 in multiple myeloma cells redirects tumor spread and prolongs survival. Hathi D, Chanswangphuwana C, Cho N, Fontana F, Maji D, Ritchey J, O'Neal J, Ghai A, Duncan K, Akers WJ, Fiala M, Vij R, DiPersio JF, Rettig M, Shokeen M. Sci Rep. 2022 Jan 7;12(1):30. doi: 10.1038/s41598-021-03748-0. PubMed
Precision targeting tumor cells using cancer-specific InDel mutations with CRISPR-Cas9. Kwon T, Ra JS, Lee S, Baek IJ, Khim KW, Lee EA, Song EK, Otarbayev D, Jung W, Park YH, Wie M, Bae J, Cheng H, Park JH, Kim N, Seo Y, Yun S, Kim HE, Moon HE, Paek SH, Park TJ, Park YU, Rhee H, Choi JH, Cho SW, Myung K. Proc Natl Acad Sci U S A. 2022 Mar 1;119(9). pii: 2103532119. doi: 10.1073/pnas.2103532119. PubMed
A transgenic mouse embryonic stem cell line for puromycin selection of V0V interneurons from heterogenous induced cultures. Pardieck J, Harb M, Sakiyama-Elbert SE. Stem Cell Res Ther. 2022 Mar 28;13(1):131. doi: 10.1186/s13287-022-02801-7. PubMed
Extru-seq: a method for predicting genome-wide Cas9 off-target sites with advantages of both cell-based and in vitro approaches. Kwon J, Kim M, Hwang W, Jo A, Hwang GH, Jung M, Kim UG, Cui G, Kim H, Eom JH, Hur JK, Lee J, Kim Y, Kim JS, Bae S, Lee JK. Genome Biol. 2023 Jan 10;24(1):4. doi: 10.1186/s13059-022-02842-4. PubMed

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