pT3TS-nCas9n Citations (95)
Originally described in: Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system.Jao LE, Wente SR, Chen W Proc Natl Acad Sci U S A. 2013 Aug 5. PubMed Journal
Articles Citing pT3TS-nCas9n
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| Targeted mutagenesis in Atlantic salmon (Salmo salar L.) using the CRISPR/Cas9 system induces complete knockout individuals in the F0 generation. Edvardsen RB, Leininger S, Kleppe L, Skaftnesmo KO, Wargelius A. PLoS One. 2014 Sep 25;9(9):e108622. doi: 10.1371/journal.pone.0108622. eCollection 2014. PubMed |
| High-throughput genome editing and phenotyping facilitated by high resolution melting curve analysis. Thomas HR, Percival SM, Yoder BK, Parant JM. PLoS One. 2014 Dec 11;9(12):e114632. doi: 10.1371/journal.pone.0114632. eCollection 2014. PubMed |
| Rapid reverse genetic screening using CRISPR in zebrafish. Shah AN, Davey CF, Whitebirch AC, Miller AC, Moens CB. Nat Methods. 2015 Jun;12(6):535-40. doi: 10.1038/nmeth.3360. Epub 2015 Apr 13. PubMed |
| CRISPR-STAT: an easy and reliable PCR-based method to evaluate target-specific sgRNA activity. Carrington B, Varshney GK, Burgess SM, Sood R. Nucleic Acids Res. 2015 Dec 15;43(22):e157. doi: 10.1093/nar/gkv802. Epub 2015 Aug 7. PubMed |
| The Autotaxin-Lysophosphatidic Acid Axis Modulates Histone Acetylation and Gene Expression during Oligodendrocyte Differentiation. Wheeler NA, Lister JA, Fuss B. J Neurosci. 2015 Aug 12;35(32):11399-414. doi: 10.1523/JNEUROSCI.0345-15.2015. PubMed |
| Generation of Targeted Mutations in Zebrafish Using the CRISPR/Cas System. Yin L, Jao LE, Chen W. Methods Mol Biol. 2015;1332:205-17. doi: 10.1007/978-1-4939-2917-7_16. PubMed |
| Accumulation of the Vitamin D Precursor Cholecalciferol Antagonizes Hedgehog Signaling to Impair Hemogenic Endothelium Formation. Cortes M, Liu SY, Kwan W, Alexa K, Goessling W, North TE. Stem Cell Reports. 2015 Oct 13;5(4):471-9. doi: 10.1016/j.stemcr.2015.08.010. Epub 2015 Sep 10. PubMed |
| Targeted candidate gene screens using CRISPR/Cas9 technology. Shah AN, Moens CB, Miller AC. Methods Cell Biol. 2016;135:89-106. doi: 10.1016/bs.mcb.2016.01.008. Epub 2016 Feb 26. PubMed |
| Optimized CRISPR-Cas9 System for Genome Editing in Zebrafish. Vejnar CE, Moreno-Mateos MA, Cifuentes D, Bazzini AA, Giraldez AJ. Cold Spring Harb Protoc. 2016 Oct 3;2016(10):pdb.prot086850. doi: 10.1101/pdb.prot086850. PubMed |
| Deep Brain Photoreceptor (val-opsin) Gene Knockout Using CRISPR/Cas Affects Chorion Formation and Embryonic Hatching in the Zebrafish. Hang CY, Moriya S, Ogawa S, Parhar IS. PLoS One. 2016 Oct 28;11(10):e0165535. doi: 10.1371/journal.pone.0165535. eCollection 2016. PubMed |
| A high-throughput functional genomics workflow based on CRISPR/Cas9-mediated targeted mutagenesis in zebrafish. Varshney GK, Carrington B, Pei W, Bishop K, Chen Z, Fan C, Xu L, Jones M, LaFave MC, Ledin J, Sood R, Burgess SM. Nat Protoc. 2016 Dec;11(12):2357-2375. doi: 10.1038/nprot.2016.141. Epub 2016 Oct 27. PubMed |
| Autolysosome biogenesis and developmental senescence are regulated by both Spns1 and v-ATPase. Sasaki T, Lian S, Khan A, Llop JR, Samuelson AV, Chen W, Klionsky DJ, Kishi S. Autophagy. 2017 Feb;13(2):386-403. doi: 10.1080/15548627.2016.1256934. Epub 2016 Nov 22. PubMed |
| Mechanical stretch triggers rapid epithelial cell division through Piezo1. Gudipaty SA, Lindblom J, Loftus PD, Redd MJ, Edes K, Davey CF, Krishnegowda V, Rosenblatt J. Nature. 2017 Mar 2;543(7643):118-121. doi: 10.1038/nature21407. Epub 2017 Feb 15. PubMed |
| Histone demethylases Kdm6ba and Kdm6bb redundantly promote cardiomyocyte proliferation during zebrafish heart ventricle maturation. Akerberg AA, Henner A, Stewart S, Stankunas K. Dev Biol. 2017 Jun 1;426(1):84-96. doi: 10.1016/j.ydbio.2017.03.030. Epub 2017 Apr 1. PubMed |
| Loss of the Habenula Intrinsic Neuromodulator Kisspeptin1 Affects Learning in Larval Zebrafish. Lupton C, Sengupta M, Cheng RK, Chia J, Thirumalai V, Jesuthasan S. eNeuro. 2017 May 19;4(3). pii: ENEURO.0326-16.2017. doi: 10.1523/ENEURO.0326-16.2017. eCollection 2017 May-Jun. PubMed |
| Wnt signaling controls pro-regenerative Collagen XII in functional spinal cord regeneration in zebrafish. Wehner D, Tsarouchas TM, Michael A, Haase C, Weidinger G, Reimer MM, Becker T, Becker CG. Nat Commun. 2017 Jul 25;8(1):126. doi: 10.1038/s41467-017-00143-0. PubMed |
| Interhost dispersal alters microbiome assembly and can overwhelm host innate immunity in an experimental zebrafish model. Burns AR, Miller E, Agarwal M, Rolig AS, Milligan-Myhre K, Seredick S, Guillemin K, Bohannan BJM. Proc Natl Acad Sci U S A. 2017 Oct 17;114(42):11181-11186. doi: 10.1073/pnas.1702511114. Epub 2017 Oct 2. PubMed |
| A shared Runx1-bound Zbtb16 enhancer directs innate and innate-like lymphoid lineage development. Mao AP, Ishizuka IE, Kasal DN, Mandal M, Bendelac A. Nat Commun. 2017 Oct 16;8(1):863. doi: 10.1038/s41467-017-00882-0. PubMed |
| G protein-coupled estrogen receptor regulates embryonic heart rate in zebrafish. Romano SN, Edwards HE, Souder JP, Ryan KJ, Cui X, Gorelick DA. PLoS Genet. 2017 Oct 24;13(10):e1007069. doi: 10.1371/journal.pgen.1007069. eCollection 2017 Oct. PubMed |
| Alk and Ltk ligands are essential for iridophore development in zebrafish mediated by the receptor tyrosine kinase Ltk. Mo ES, Cheng Q, Reshetnyak AV, Schlessinger J, Nicoli S. Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):12027-12032. doi: 10.1073/pnas.1710254114. Epub 2017 Oct 23. PubMed |
| Nuclear Androgen Receptor Regulates Testes Organization and Oocyte Maturation in Zebrafish. Crowder CM, Lassiter CS, Gorelick DA. Endocrinology. 2018 Feb 1;159(2):980-993. doi: 10.1210/en.2017-00617. PubMed |
| apterous A specifies dorsal wing patterns and sexual traits in butterflies. Prakash A, Monteiro A. Proc Biol Sci. 2018 Feb 28;285(1873). pii: rspb.2017.2685. doi: 10.1098/rspb.2017.2685. PubMed |
| Cystathionine beta-Synthase Is Necessary for Axis Development in Vivo. Prabhudesai S, Koceja C, Dey A, Eisa-Beygi S, Leigh NR, Bhattacharya R, Mukherjee P, Ramchandran R. Front Cell Dev Biol. 2018 Feb 16;6:14. doi: 10.3389/fcell.2018.00014. eCollection 2018. PubMed |
| Genetic analysis of zebrafish homologs of human FOXQ1, foxq1a and foxq1b, in innate immune cell development and bacterial host response. Earley AM, Dixon CT, Shiau CE. PLoS One. 2018 Mar 13;13(3):e0194207. doi: 10.1371/journal.pone.0194207. eCollection 2018. PubMed |
| The Hippo pathway effector Wwtr1 regulates cardiac wall maturation in zebrafish. Lai JKH, Collins MM, Uribe V, Jimenez-Amilburu V, Gunther S, Maischein HM, Stainier DYR. Development. 2018 May 17;145(10). pii: 145/10/dev159210. doi: 10.1242/dev.159210. PubMed |
| Usherin defects lead to early-onset retinal dysfunction in zebrafish. Dona M, Slijkerman R, Lerner K, Broekman S, Wegner J, Howat T, Peters T, Hetterschijt L, Boon N, de Vrieze E, Sorusch N, Wolfrum U, Kremer H, Neuhauss S, Zang J, Kamermans M, Westerfield M, Phillips J, van Wijk E. Exp Eye Res. 2018 Aug;173:148-159. doi: 10.1016/j.exer.2018.05.015. Epub 2018 May 16. PubMed |
| Optimized knock-in of point mutations in zebrafish using CRISPR/Cas9. Prykhozhij SV, Fuller C, Steele SL, Veinotte CJ, Razaghi B, Robitaille JM, McMaster CR, Shlien A, Malkin D, Berman JN. Nucleic Acids Res. 2018 Sep 28;46(17):e102. doi: 10.1093/nar/gky512. PubMed |
| Zebrafish mutants and TEAD reporters reveal essential functions for Yap and Taz in posterior cardinal vein development. Astone M, Lai JKH, Dupont S, Stainier DYR, Argenton F, Vettori A. Sci Rep. 2018 Jul 5;8(1):10189. doi: 10.1038/s41598-018-27657-x. PubMed |
| A molecular mechanism for Wnt ligand-specific signaling. Eubelen M, Bostaille N, Cabochette P, Gauquier A, Tebabi P, Dumitru AC, Koehler M, Gut P, Alsteens D, Stainier DYR, Garcia-Pino A, Vanhollebeke B. Science. 2018 Aug 17;361(6403). pii: science.aat1178. doi: 10.1126/science.aat1178. Epub 2018 Jul 19. PubMed |
| Multiplexed CRISPR/Cas9 Targeting of Genes Implicated in Retinal Regeneration and Degeneration. Unal Eroglu A, Mulligan TS, Zhang L, White DT, Sengupta S, Nie C, Lu NY, Qian J, Xu L, Pei W, Burgess SM, Saxena MT, Mumm JS. Front Cell Dev Biol. 2018 Aug 21;6:88. doi: 10.3389/fcell.2018.00088. eCollection 2018. PubMed |
| Robust activation of microhomology-mediated end joining for precision gene editing applications. Ata H, Ekstrom TL, Martinez-Galvez G, Mann CM, Dvornikov AV, Schaefbauer KJ, Ma AC, Dobbs D, Clark KJ, Ekker SC. PLoS Genet. 2018 Sep 12;14(9):e1007652. doi: 10.1371/journal.pgen.1007652. eCollection 2018 Sep. PubMed |
| Targeted disruption of the endogenous zebrafish rhodopsin locus as models of rapid rod photoreceptor degeneration. Zelinka CP, Sotolongo-Lopez M, Fadool JM. Mol Vis. 2018 Aug 27;24:587-602. eCollection 2018. PubMed |
| Poor Splice-Site Recognition in a Humanized Zebrafish Knockin Model for the Recurrent Deep-Intronic c.7595-2144A>G Mutation in USH2A. Slijkerman R, Goloborodko A, Broekman S, de Vrieze E, Hetterschijt L, Peters T, Gerits M, Kremer H, van Wijk E. Zebrafish. 2018 Dec;15(6):597-609. doi: 10.1089/zeb.2018.1613. Epub 2018 Oct 3. PubMed |
| Color opponency with a single kind of bistable opsin in the zebrafish pineal organ. Wada S, Shen B, Kawano-Yamashita E, Nagata T, Hibi M, Tamotsu S, Koyanagi M, Terakita A. Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):11310-11315. doi: 10.1073/pnas.1802592115. Epub 2018 Oct 15. PubMed |
| Precise A*T to G*C base editing in the zebrafish genome. Qin W, Lu X, Liu Y, Bai H, Li S, Lin S. BMC Biol. 2018 Nov 20;16(1):139. doi: 10.1186/s12915-018-0609-1. PubMed |
| The mineralocorticoid receptor is essential for stress axis regulation in zebrafish larvae. Faught E, Vijayan MM. Sci Rep. 2018 Dec 27;8(1):18081. doi: 10.1038/s41598-018-36681-w. PubMed |
| Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport. Insinna C, Lu Q, Teixeira I, Harned A, Semler EM, Stauffer J, Magidson V, Tiwari A, Kenworthy AK, Narayan K, Westlake CJ. Nat Commun. 2019 Jan 25;10(1):428. doi: 10.1038/s41467-018-08192-9. PubMed |
Intestinal Serum amyloid A suppresses systemic neutrophil activation and bactericidal activity in response to microbiota colonization.
Murdoch CC, Espenschied ST, Matty MA, Mueller O, Tobin DM, Rawls JF.
PLoS Pathog. 2019 Mar 7;15(3):e1007381. doi: 10.1371/journal.ppat.1007381. eCollection 2019 Mar.
PubMed
Associated Plasmids |
| GPCR-independent activation of G proteins promotes apical cell constriction in vivo. Marivin A, Morozova V, Walawalkar I, Leyme A, Kretov DA, Cifuentes D, Dominguez I, Garcia-Marcos M. J Cell Biol. 2019 May 6;218(5):1743-1763. doi: 10.1083/jcb.201811174. Epub 2019 Apr 4. PubMed |
| Guidelines for optimized gene knockout using CRISPR/Cas9. Campenhout CV, Cabochette P, Veillard AC, Laczik M, Zelisko-Schmidt A, Sabatel C, Dhainaut M, Vanhollebeke B, Gueydan C, Kruys V. Biotechniques. 2019 Jun;66(6):295-302. doi: 10.2144/btn-2018-0187. Epub 2019 May 1. PubMed |
| Manipulation of Gene Function in Mexican Cavefish. Stahl BA, Jaggard JB, Chin JSR, Kowalko JE, Keene AC, Duboue ER. J Vis Exp. 2019 Apr 22;(146). doi: 10.3791/59093. PubMed |
| Genome-wide strategies reveal target genes of Npas4l associated with vascular development in zebrafish. Marass M, Beisaw A, Gerri C, Luzzani F, Fukuda N, Gunther S, Kuenne C, Reischauer S, Stainier DYR. Development. 2019 Jun 3;146(11). pii: dev.173427. doi: 10.1242/dev.173427. PubMed |
| CRISPR/Cas9-mediated ablation of elovl2 in Atlantic salmon (Salmo salar L.) inhibits elongation of polyunsaturated fatty acids and induces Srebp-1 and target genes. Datsomor AK, Zic N, Li K, Olsen RE, Jin Y, Vik JO, Edvardsen RB, Grammes F, Wargelius A, Winge P. Sci Rep. 2019 May 17;9(1):7533. doi: 10.1038/s41598-019-43862-8. PubMed |
| CRISPR-Cas9 Mediated Genome Editing in Bicyclus anynana Butterflies. Banerjee TD, Monteiro A. Methods Protoc. 2018 May 15;1(2). pii: mps1020016. doi: 10.3390/mps1020016. PubMed |
| Agouti-Related Protein 2 Is a New Player in the Teleost Stress Response System. Shainer I, Michel M, Marquart GD, Bhandiwad AA, Zmora N, Ben-Moshe Livne Z, Zohar Y, Hazak A, Mazon Y, Forster D, Hollander-Cohen L, Cone RD, Burgess HA, Gothilf Y. Curr Biol. 2019 Jun 17;29(12):2009-2019.e7. doi: 10.1016/j.cub.2019.05.021. Epub 2019 Jun 6. PubMed |
| Brd4 and P300 Confer Transcriptional Competency during Zygotic Genome Activation. Chan SH, Tang Y, Miao L, Darwich-Codore H, Vejnar CE, Beaudoin JD, Musaev D, Fernandez JP, Benitez MDJ, Bazzini AA, Moreno-Mateos MA, Giraldez AJ. Dev Cell. 2019 Jun 17;49(6):867-881.e8. doi: 10.1016/j.devcel.2019.05.037. PubMed |
| TAF1, associated with intellectual disability in humans, is essential for embryogenesis and regulates neurodevelopmental processes in zebrafish. Gudmundsson S, Wilbe M, Filipek-Gorniok B, Molin AM, Ekvall S, Johansson J, Allalou A, Gylje H, Kalscheuer VM, Ledin J, Anneren G, Bondeson ML. Sci Rep. 2019 Jul 24;9(1):10730. doi: 10.1038/s41598-019-46632-8. PubMed |
| Creation of zebrafish knock-in reporter lines in the nefma gene by Cas9-mediated homologous recombination. Eschstruth A, Schneider-Maunoury S, Giudicelli F. Genesis. 2020 Jan;58(1):e23340. doi: 10.1002/dvg.23340. Epub 2019 Sep 30. PubMed |
| Loss of rps9 in Zebrafish Leads to p53-Dependent Anemia. Chen C, Huang H, Yan R, Lin S, Qin W. G3 (Bethesda). 2019 Dec 3;9(12):4149-4157. doi: 10.1534/g3.119.400585. PubMed |
| CRISPR/Cas9-mediated editing of Delta5 and Delta6 desaturases impairs Delta8-desaturation and docosahexaenoic acid synthesis in Atlantic salmon (Salmo salar L.). Datsomor AK, Olsen RE, Zic N, Madaro A, Bones AM, Edvardsen RB, Wargelius A, Winge P. Sci Rep. 2019 Nov 15;9(1):16888. doi: 10.1038/s41598-019-53316-w. PubMed |
| Clinical and preclinical therapeutic outcome metrics for USH2A-related disease. Toms M, Dubis AM, de Vrieze E, Tracey-White D, Mitsios A, Hayes M, Broekman S, Baxendale S, Utoomprurkporn N, Bamiou D, Bitner-Glindzicz M, Webster AR, Van Wijk E, Moosajee M. Hum Mol Genet. 2020 Jul 21;29(11):1882-1899. doi: 10.1093/hmg/ddaa004. PubMed |
| Temporal and spatial expression of zebrafish mctp genes and evaluation of frameshift alleles of mctp2b. Espino-Saldana AE, Duran-Rios K, Olivares-Hernandez E, Rodriguez-Ortiz R, Arellano-Carbajal F, Martinez-Torres A. Gene. 2020 May 15;738:144371. doi: 10.1016/j.gene.2020.144371. Epub 2020 Jan 27. PubMed |
| Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency. Luciani A, Schumann A, Berquez M, Chen Z, Nieri D, Failli M, Debaix H, Festa BP, Tokonami N, Raimondi A, Cremonesi A, Carrella D, Forny P, Kolker S, Diomedi Camassei F, Diaz F, Moraes CT, Di Bernardo D, Baumgartner MR, Devuyst O. Nat Commun. 2020 Feb 20;11(1):970. doi: 10.1038/s41467-020-14729-8. PubMed |
| miR-103/107 regulates left-right asymmetry in zebrafish by modulating Kupffer's vesicle development and ciliogenesis. Heigwer J, Kutzner J, Haeussler M, Burkhalter MD, Draebing T, Juergensen L, Katus HA, Philipp M, Westhoff JH, Hassel D. Biochem Biophys Res Commun. 2020 Jun 25;527(2):432-439. doi: 10.1016/j.bbrc.2020.04.066. Epub 2020 Apr 22. PubMed |
| cells. W. - PubMed |
| Physiological impact and comparison of mutant screening methods in piwil2 KO founder Nile tilapia produced by CRISPR/Cas9 system. Jin YH, Liao B, Migaud H, Davie A. Sci Rep. 2020 Jul 28;10(1):12600. doi: 10.1038/s41598-020-69421-0. PubMed |
| Targeting lactate dehydrogenase A (LDHA) exerts antileukemic effects on T-cell acute lymphoblastic leukemia. Yu H, Yin Y, Yi Y, Cheng Z, Kuang W, Li R, Zhong H, Cui Y, Yuan L, Gong F, Wang Z, Li H, Peng H, Zhang G. Cancer Commun (Lond). 2020 Oct;40(10):501-517. doi: 10.1002/cac2.12080. Epub 2020 Aug 21. PubMed |
Cre-Controlled CRISPR mutagenesis provides fast and easy conditional gene inactivation in zebrafish.
Hans S, Zoller D, Hammer J, Stucke J, Spiess S, Kesavan G, Kroehne V, Eguiguren JS, Ezhkova D, Petzold A, Dahl A, Brand M.
Nat Commun. 2021 Feb 18;12(1):1125. doi: 10.1038/s41467-021-21427-6.
PubMed
Associated Plasmids |
| The recycling endosome protein Rab25 coordinates collective cell movements in the zebrafish surface epithelium. Willoughby PM, Allen M, Yu J, Korytnikov R, Chen T, Liu Y, So I, Macpherson N, Mitchell JA, Fernandez-Gonzalez R, Bruce AE. Elife. 2021 Mar 23;10. pii: 66060. doi: 10.7554/eLife.66060. PubMed |
| Chromatin remodeller CHD7 is required for GABAergic neuron development by promoting PAQR3 expression. Jamadagni P, Breuer M, Schmeisser K, Cardinal T, Kassa B, Parker JA, Pilon N, Samarut E, Patten SA. EMBO Rep. 2021 Jun 4;22(6):e50958. doi: 10.15252/embr.202050958. Epub 2021 Apr 26. PubMed |
| Effect of ARTEMIS (DCLRE1C) deficiency and microinjection timing on editing efficiency during somatic cell nuclear transfer and in vitro fertilization using the CRISPR/Cas9 system. Li Y, Adur MK, Wang W, Schultz RB, Hale B, Wierson W, Charley SE, McGrail M, Essner J, Tuggle CK, Ross JW. Theriogenology. 2021 Aug;170:107-116. doi: 10.1016/j.theriogenology.2021.04.003. Epub 2021 May 3. PubMed |
| Puma, noxa, p53, and p63 differentially mediate stress pathway induced apoptosis. Wang J, Thomas HR, Li Z, Yeo NCF, Scott HE, Dang N, Hossain MI, Andrabi SA, Parant JM. Cell Death Dis. 2021 Jun 30;12(7):659. doi: 10.1038/s41419-021-03902-6. PubMed |
| A comprehensive series of Irx cluster mutants reveals diverse roles in facial cartilage development. Farmer DT, Patel P, Choi R, Liu CY, Crump JG. Development. 2021 Aug 15;148(16). pii: 271157. doi: 10.1242/dev.197244. Epub 2021 Aug 16. PubMed |
| The broad role of Nkx3.2 in the development of the zebrafish axial skeleton. Waldmann L, Leyhr J, Zhang H, Ohman-Magi C, Allalou A, Haitina T. PLoS One. 2021 Aug 19;16(8):e0255953. doi: 10.1371/journal.pone.0255953. eCollection 2021. PubMed |
| Genome Editing in Zebrafish by ScCas9 Recognizing NNG PAM. Liu Y, Liang F, Dong Z, Li S, Ye J, Qin W. Cells. 2021 Aug 16;10(8). pii: cells10082099. doi: 10.3390/cells10082099. PubMed |
Stress hematopoiesis induces a proliferative advantage in TET2 deficiency.
Rajan V, Collett K, Woodside R, Prykhozhij SV, Moksa M, Carles A, Wong M, Liebman M, Hirst M, Berman JN.
Leukemia. 2021 Sep 30. pii: 10.1038/s41375-021-01427-7. doi: 10.1038/s41375-021-01427-7.
PubMed
Associated Plasmids |
| Differential Requirement of Gata2a and Gata2b for Primitive and Definitive Myeloid Development in Zebrafish. Pena OA, Lubin A, Rowell J, Hoade Y, Khokhar N, Lemmik H, Mahony C, Dace P, Umamahesan C, Payne EM. Front Cell Dev Biol. 2021 Sep 13;9:708113. doi: 10.3389/fcell.2021.708113. eCollection 2021. PubMed |
| Autophagy coordinates chondrocyte development and early joint formation in zebrafish. Moss JJ, Wirth M, Tooze SA, Lane JD, Hammond CL. FASEB J. 2021 Nov;35(11):e22002. doi: 10.1096/fj.202101167R. PubMed |
| Adhesion G protein-coupled receptor Gpr126/Adgrg6 is essential for placental development. Torregrosa-Carrion R, Pineiro-Sabaris R, Siguero-Alvarez M, Grego-Bessa J, Luna-Zurita L, Fernandes VS, MacGrogan D, Stainier DYR, de la Pompa JL. Sci Adv. 2021 Nov 12;7(46):eabj5445. doi: 10.1126/sciadv.abj5445. Epub 2021 Nov 12. PubMed |
| Butterfly eyespots evolved via cooption of an ancestral gene-regulatory network that also patterns antennae, legs, and wings. Murugesan SN, Connahs H, Matsuoka Y, Das Gupta M, Tiong GJL, Huq M, Gowri V, Monroe S, Deem KD, Werner T, Tomoyasu Y, Monteiro A. Proc Natl Acad Sci U S A. 2022 Feb 22;119(8). pii: 2108661119. doi: 10.1073/pnas.2108661119. PubMed |
| Chondroitin/dermatan sulfate glycosyltransferase genes are essential for craniofacial development. Habicher J, Varshney GK, Waldmann L, Snitting D, Allalou A, Zhang H, Ghanem A, Ohman Magi C, Dierker T, Kjellen L, Burgess SM, Ledin J. PLoS Genet. 2022 Feb 22;18(2):e1010067. doi: 10.1371/journal.pgen.1010067. eCollection 2022 Feb. PubMed |
| Contingent stimulus delivery assay for zebrafish reveals a role for CCSER1 in alcohol preference. Nathan FM, Kibat C, Goel T, Stewart J, Claridge-Chang A, Mathuru AS. Addict Biol. 2022 Mar;27(2):e13126. doi: 10.1111/adb.13126. PubMed |
| An integrated model for Gpr124 function in Wnt7a/b signaling among vertebrates. America M, Bostaille N, Eubelen M, Martin M, Stainier DYR, Vanhollebeke B. Cell Rep. 2022 May 31;39(9):110902. doi: 10.1016/j.celrep.2022.110902. PubMed |
| SpG and SpRY variants expand the CRISPR toolbox for genome editing in zebrafish. Liang F, Zhang Y, Li L, Yang Y, Fei JF, Liu Y, Qin W. Nat Commun. 2022 Jun 14;13(1):3421. doi: 10.1038/s41467-022-31034-8. PubMed |
Cre/lox regulated conditional rescue and inactivation with zebrafish UFlip alleles generated by CRISPR-Cas9 targeted integration.
Liu F, Kambakam S, Almeida MP, Ming Z, Welker JM, Wierson WA, Schultz-Rogers LE, Ekker SC, Clark KJ, Essner JJ, McGrail M.
Elife. 2022 Jun 17;11. pii: 71478. doi: 10.7554/eLife.71478.
PubMed
Associated Plasmids |
| Reduced sister chromatid cohesion acts as a tumor penetrance modifier. Wang J, Thomas HR, Chen Y, Percival SM, Waldrep SC, Ramaker RC, Thompson RG, Cooper SJ, Chong Z, Parant JM. PLoS Genet. 2022 Aug 22;18(8):e1010341. doi: 10.1371/journal.pgen.1010341. eCollection 2022 Aug. PubMed |
| Variable paralog expression underlies phenotype variation. Bailon-Zambrano R, Sucharov J, Mumme-Monheit A, Murry M, Stenzel A, Pulvino AT, Mitchell JM, Colborn KL, Nichols JT. Elife. 2022 Sep 22;11:e79247. doi: 10.7554/eLife.79247. PubMed |
| The developing epicardium regulates cardiac chamber morphogenesis by promoting cardiomyocyte growth. Boezio GLM, Zhao S, Gollin J, Priya R, Mansingh S, Guenther S, Fukuda N, Gunawan F, Stainier DYR. Dis Model Mech. 2023 May 1;16(5):dmm049571. doi: 10.1242/dmm.049571. Epub 2022 Oct 19. PubMed |
| Ultrabithorax modifies a regulatory network of genes essential for butterfly eyespot development in a wing sector-specific manner. Matsuoka Y, Monteiro A. Development. 2022 Dec 1;149(23):dev200781. doi: 10.1242/dev.200781. Epub 2022 Dec 1. PubMed |
| A novel cis-regulatory element drives early expression of Nkx3.2 in the gnathostome primary jaw joint. Leyhr J, Waldmann L, Filipek-Gorniok B, Zhang H, Allalou A, Haitina T. Elife. 2022 Nov 15;11:e75749. doi: 10.7554/eLife.75749. PubMed |
| Parental mutations influence wild-type offspring via transcriptional adaptation. Jiang Z, El-Brolosy MA, Serobyan V, Welker JM, Retzer N, Dooley CM, Jakutis G, Juan T, Fukuda N, Maischein HM, Balciunas D, Stainier DYR. Sci Adv. 2022 Nov 25;8(47):eabj2029. doi: 10.1126/sciadv.abj2029. Epub 2022 Nov 25. PubMed |
| Variable phenotypes and penetrance between and within different zebrafish ciliary transition zone mutants. Wang J, Thomas HR, Thompson RG, Waldrep SC, Fogerty J, Song P, Li Z, Ma Y, Santra P, Hoover JD, Yeo NC, Drummond IA, Yoder BK, Amack JD, Perkins B, Parant JM. Dis Model Mech. 2022 Dec 1;15(12):dmm049568. doi: 10.1242/dmm.049568. Epub 2022 Dec 19. PubMed |
| Loss of mitochondrial Chchd10 or Chchd2 in zebrafish leads to an ALS-like phenotype and Complex I deficiency independent of the mitochondrial integrated stress response. Petel Legare V, Rampal CJ, Gurberg TJN, Aaltonen MJ, Janer A, Zinman L, Shoubridge EA, Armstrong GAB. Dev Neurobiol. 2023 Jan;83(1-2):54-69. doi: 10.1002/dneu.22909. Epub 2023 Mar 2. PubMed |
| Loss of calpain3b in Zebrafish, a Model of Limb-Girdle Muscular Dystrophy, Increases Susceptibility to Muscle Defects Due to Elevated Muscle Activity. Prykhozhij SV, Caceres L, Ban K, Cordeiro-Santanach A, Nagaraju K, Hoffman EP, Berman JN. Genes (Basel). 2023 Feb 15;14(2):492. doi: 10.3390/genes14020492. PubMed |
| Actomyosin contractility in olfactory placode neurons opens the skin epithelium to form the zebrafish nostril. Baraban M, Gordillo Pi C, Bonnet I, Gilles JF, Lejeune C, Cabrera M, Tep F, Breau MA. Dev Cell. 2023 Mar 13;58(5):361-375.e5. doi: 10.1016/j.devcel.2023.02.001. Epub 2023 Feb 24. PubMed |
| In vivo DNA methylation editing in zebrafish. Liang F, Dong Z, Ye J, Hu W, Bhandari RK, Mai K, Wang X. Epigenetics. 2023 Dec;18(1):2192326. doi: 10.1080/15592294.2023.2192326. PubMed |
| Susceptibility and Permissivity of Zebrafish (Danio rerio) Larvae to Cypriniviruses. Streiff C, He B, Morvan L, Zhang H, Delrez N, Fourrier M, Manfroid I, Suarez NM, Betoulle S, Davison AJ, Donohoe O, Vanderplasschen A. Viruses. 2023 Mar 17;15(3):768. doi: 10.3390/v15030768. PubMed |
| The non-canonical Wnt receptor Ror2 is required for cartilage cell polarity and morphogenesis of the craniofacial skeleton in zebrafish. Dranow DB, Le Pabic P, Schilling TF. Development. 2023 Apr 15;150(8):dev201273. doi: 10.1242/dev.201273. Epub 2023 Apr 21. PubMed |
| Nucleolar Protein 56 Deficiency in Zebrafish Leads to Developmental Abnormalities and Anemia via p53 and JAK2-STAT3 Signaling. Liang F, Lu X, Wu B, Yang Y, Qin W. Biology (Basel). 2023 Mar 31;12(4):538. doi: 10.3390/biology12040538. PubMed |
| Local angiogenic interplay of Vegfc/d and Vegfa controls brain region-specific emergence of fenestrated capillaries. Parab S, Card OA, Chen Q, America M, Buck LD, Quick RE, Horrigan WF, Levkowitz G, Vanhollebeke B, Matsuoka RL. Elife. 2023 May 16;12:e86066. doi: 10.7554/eLife.86066. PubMed |
| A CRISPR-Cas9 mutation in sox9b long intergenic noncoding RNA (slincR) affects zebrafish development, behavior, and regeneration. Dasgupta S, LaDu JK, Garcia GR, Li S, Tomono-Duval K, Rericha Y, Huang L, Tanguay RL. Toxicol Sci. 2023 Jul 28;194(2):153-166. doi: 10.1093/toxsci/kfad050. PubMed |
| Cfdp1 Is Essential for Cardiac Development and Function. Giardoglou P, Deloukas P, Dedoussis G, Beis D. Cells. 2023 Aug 3;12(15):1994. doi: 10.3390/cells12151994. PubMed |
| Lepidopteran prolegs are novel traits, not leg homologs. Matsuoka Y, Murugesan SN, Prakash A, Monteiro A. Sci Adv. 2023 Oct 13;9(41):eadd9389. doi: 10.1126/sciadv.add9389. Epub 2023 Oct 12. PubMed |
| HIF signaling overactivation inhibits lateral line neuromast development through Wnt in zebrafish. Zhang R, Ma Z, Wang J, Fan C. Gene. 2024 Mar 10;898:148077. doi: 10.1016/j.gene.2023.148077. Epub 2023 Dec 12. PubMed |
| Generation of a Zebrafish Knock-In Model Recapitulating Childhood ETV6::RUNX1-Positive B-Cell Precursor Acute Lymphoblastic Leukemia. Zapilko V, Moisio S, Parikka M, Heinaniemi M, Lohi O. Cancers (Basel). 2023 Dec 13;15(24):5821. doi: 10.3390/cancers15245821. PubMed |
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