pRK5-EGFP-Tau Citations (32)
Originally described in: Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration.Hoover BR, Reed MN, Su J, Penrod RD, Kotilinek LA, Grant MK, Pitstick R, Carlson GA, Lanier LM, Yuan LL, Ashe KH, Liao D Neuron. 2010 Dec 22;68(6):1067-81. doi: 10.1016/j.neuron.2010.11.030. PubMed Journal
Articles Citing pRK5-EGFP-Tau
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Reduction of Nuak1 Decreases Tau and Reverses Phenotypes in a Tauopathy Mouse Model.
Lasagna-Reeves CA, de Haro M, Hao S, Park J, Rousseaux MW, Al-Ramahi I, Jafar-Nejad P, Vilanova-Velez L, See L, De Maio A, Nitschke L, Wu Z, Troncoso JC, Westbrook TF, Tang J, Botas J, Zoghbi HY.
Neuron. 2016 Oct 19;92(2):407-418. doi: 10.1016/j.neuron.2016.09.022. Epub 2016 Oct 6.
PubMed
Associated Plasmids |
| Assessing the degradation of tau in primary neurons: The role of autophagy. Ji C, Tang M, Johnson GVW. Methods Cell Biol. 2017;141:229-244. doi: 10.1016/bs.mcb.2017.06.011. Epub 2017 Jul 31. PubMed |
| The tyrosine phosphatase PTPN13/FAP-1 links calpain-2, TBI and tau tyrosine phosphorylation. Wang Y, Hall RA, Lee M, Kamgar-Parsi A, Bi X, Baudry M. Sci Rep. 2017 Sep 18;7(1):11771. doi: 10.1038/s41598-017-12236-3. PubMed |
| Tau hyperphosphorylation induces oligomeric insulin accumulation and insulin resistance in neurons. Rodriguez-Rodriguez P, Sandebring-Matton A, Merino-Serrais P, Parrado-Fernandez C, Rabano A, Winblad B, Avila J, Ferrer I, Cedazo-Minguez A. Brain. 2017 Dec 1;140(12):3269-3285. doi: 10.1093/brain/awx256. PubMed |
| The Golgi ribbon in mammalian cells negatively regulates autophagy by modulating mTOR activity. Gosavi P, Houghton FJ, McMillan PJ, Hanssen E, Gleeson PA. J Cell Sci. 2018 Feb 8;131(3). pii: jcs.211987. doi: 10.1242/jcs.211987. PubMed |
| Discovery of a Keap1-dependent peptide PROTAC to knockdown Tau by ubiquitination-proteasome degradation pathway. Lu M, Liu T, Jiao Q, Ji J, Tao M, Liu Y, You Q, Jiang Z. Eur J Med Chem. 2018 Feb 25;146:251-259. doi: 10.1016/j.ejmech.2018.01.063. Epub 2018 Feb 4. PubMed |
| DNAJC5 facilitates USP19-dependent unconventional secretion of misfolded cytosolic proteins. Xu Y, Cui L, Dibello A, Wang L, Lee J, Saidi L, Lee JG, Ye Y. Cell Discov. 2018 Mar 6;4:11. doi: 10.1038/s41421-018-0012-7. eCollection 2018. PubMed |
| Directed evolution of a picomolar-affinity, high-specificity antibody targeting phosphorylated tau. Li D, Wang L, Maziuk BF, Yao X, Wolozin B, Cho YK. J Biol Chem. 2018 Aug 3;293(31):12081-12094. doi: 10.1074/jbc.RA118.003557. Epub 2018 Jun 13. PubMed |
| A genetic model to study O-GlcNAc cycling in immortalized mouse embryonic fibroblasts. St Amand MM, Bond MR, Riedy J, Comly M, Shiloach J, Hanover JA. J Biol Chem. 2018 Aug 31;293(35):13673-13681. doi: 10.1074/jbc.RA118.004059. Epub 2018 Jun 28. PubMed |
| Endolysosomal degradation of Tau and its role in glucocorticoid-driven hippocampal malfunction. Vaz-Silva J, Gomes P, Jin Q, Zhu M, Zhuravleva V, Quintremil S, Meira T, Silva J, Dioli C, Soares-Cunha C, Daskalakis NP, Sousa N, Sotiropoulos I, Waites CL. EMBO J. 2018 Oct 15;37(20). pii: embj.201899084. doi: 10.15252/embj.201899084. Epub 2018 Aug 30. PubMed |
| Intersectin-1 interacts with the golgin GCC88 to couple the actin network and Golgi architecture. Makhoul C, Gosavi P, Duffield R, Delbridge B, Williamson NA, Gleeson PA. Mol Biol Cell. 2019 Feb 1;30(3):370-386. doi: 10.1091/mbc.E18-05-0313. Epub 2018 Dec 12. PubMed |
| Pathogenic tau does not drive activation of the unfolded protein response. Pitera AP, Asuni AA, O'Connor V, Deinhardt K. J Biol Chem. 2019 Jun 21;294(25):9679-9688. doi: 10.1074/jbc.RA119.008263. Epub 2019 May 3. PubMed |
| Phosphorylation in two discrete tau domains regulates a stepwise process leading to postsynaptic dysfunction. Teravskis PJ, Oxnard BR, Miller EC, Kemper L, Ashe KH, Liao D. J Physiol. 2019 Jun 13. doi: 10.1113/JP277459. PubMed |
| Autophagy-mediated secretory pathway is responsible for both normal and pathological tau in neurons. Kang S, Son SM, Baik SH, Yang J, Mook-Jung I. J Alzheimers Dis. 2019 Jun 24. pii: JAD190180. doi: 10.3233/JAD-190180. PubMed |
| High specificity of widely used phospho-tau antibodies validated using a quantitative whole-cell based assay. Li D, Cho YK. J Neurochem. 2020 Jan;152(1):122-135. doi: 10.1111/jnc.14830. Epub 2019 Sep 4. PubMed |
| Tau Misfolding Efficiently Propagates between Individual Intact Hippocampal Neurons. Hallinan GI, Vargas-Caballero M, West J, Deinhardt K. J Neurosci. 2019 Nov 27;39(48):9623-9632. doi: 10.1523/JNEUROSCI.1590-19.2019. Epub 2019 Oct 28. PubMed |
| The KLDpT activation loop motif is critical for MARK kinase activity. Sonntag T, Moresco JJ, Yates JR 3rd, Montminy M. PLoS One. 2019 Dec 3;14(12):e0225727. doi: 10.1371/journal.pone.0225727. eCollection 2019. PubMed |
| Tau induces PSD95-neuronal NOS uncoupling and neurovascular dysfunction independent of neurodegeneration. Park L, Hochrainer K, Hattori Y, Ahn SJ, Anfray A, Wang G, Uekawa K, Seo J, Palfini V, Blanco I, Acosta D, Eliezer D, Zhou P, Anrather J, Iadecola C. Nat Neurosci. 2020 Sep;23(9):1079-1089. doi: 10.1038/s41593-020-0686-7. Epub 2020 Aug 10. PubMed |
| Soluble 4R0N Tau Abrogates Endocytic Vesicular Dynamics. Mahendran TS, Suresh SN, Garimella L, Manjithaya R. Front Aging Neurosci. 2020 Nov 5;12:537712. doi: 10.3389/fnagi.2020.537712. eCollection 2020. PubMed |
| Hydrogen sulfide is neuroprotective in Alzheimer's disease by sulfhydrating GSK3beta and inhibiting Tau hyperphosphorylation. Giovinazzo D, Bursac B, Sbodio JI, Nalluru S, Vignane T, Snowman AM, Albacarys LM, Sedlak TW, Torregrossa R, Whiteman M, Filipovic MR, Snyder SH, Paul BD. Proc Natl Acad Sci U S A. 2021 Jan 26;118(4). pii: 2017225118. doi: 10.1073/pnas.2017225118. PubMed |
| Staufen1 in Human Neurodegeneration. Paul S, Dansithong W, Figueroa KP, Gandelman M, Scoles DR, Pulst SM. Ann Neurol. 2021 Jun;89(6):1114-1128. doi: 10.1002/ana.26069. Epub 2021 Apr 8. PubMed |
| The small molecule DIPQUO promotes osteogenic differentiation via inhibition of glycogen synthase kinase 3-beta signaling. Cook B, Walker N, Zhang Q, Chen S, Evans T. J Biol Chem. 2021 Jan-Jun;296:100696. doi: 10.1016/j.jbc.2021.100696. Epub 2021 Apr 22. PubMed |
| Monitoring the interactions between alpha-synuclein and Tau in vitro and in vivo using bimolecular fluorescence complementation. Torres-Garcia L, P Domingues JM, Brandi E, Haikal C, Mudannayake JM, Bras IC, Gerhardt E, Li W, Svanbergsson A, Outeiro TF, Gouras GK, Li JY. Sci Rep. 2022 Feb 22;12(1):2987. doi: 10.1038/s41598-022-06846-9. PubMed |
| SOD1 mediates lysosome-to-mitochondria communication and its dysregulation by amyloid-beta oligomers. Norambuena A, Sun X, Wallrabe H, Cao R, Sun N, Pardo E, Shivange N, Wang DB, Post LA, Ferris HA, Hu S, Periasamy A, Bloom GS. Neurobiol Dis. 2022 Jul;169:105737. doi: 10.1016/j.nbd.2022.105737. Epub 2022 Apr 20. PubMed |
| Sequestration of TDP-43(216-414) Aggregates by Cytoplasmic Expression of the proSAAS Chaperone. Peinado JR, Chaplot K, Jarvela TS, Barbieri EM, Shorter J, Lindberg I. ACS Chem Neurosci. 2022 Jun 1;13(11):1651-1665. doi: 10.1021/acschemneuro.2c00156. Epub 2022 May 12. PubMed |
| Zinc enhances autophagic flux and lysosomal function through transcription factor EB activation and V-ATPase assembly. Kim KR, Park SE, Hong JY, Koh JY, Cho DH, Hwang JJ, Kim YH. Front Cell Neurosci. 2022 Sep 29;16:895750. doi: 10.3389/fncel.2022.895750. eCollection 2022. PubMed |
| Chaperoning activity of the cyclophilin family prevents tau aggregation. Hill SE, Esquivel AR, Ospina SR, Rahal LM, Dickey CA, Blair LJ. Protein Sci. 2022 Nov;31(11):e4448. doi: 10.1002/pro.4448. PubMed |
Localization, induction, and cellular effects of tau phosphorylated at threonine 217.
Rajbanshi B, Guruacharya A, Mandell JW, Bloom GS.
Alzheimers Dement. 2023 Jan 12. doi: 10.1002/alz.12892.
PubMed
Associated Plasmids |
| Long non-coding RNA SNHG8 drives stress granule formation in tauopathies. Bhagat R, Minaya MA, Renganathan A, Mehra M, Marsh J, Martinez R, Nana AL, Spina S, Seeley WW, Grinberg LT, Karch CM. medRxiv [Preprint]. 2023 Mar 1:2023.02.27.23286548. doi: 10.1101/2023.02.27.23286548. PubMed |
| Reduction of Spermine Synthase Suppresses Tau Accumulation Through Autophagy Modulation in Tauopathy. Tao X, Liu J, Diaz-Perez Z, Foley JR, Stewart TM, Casero RA, Zhai RG. bioRxiv. 2023 Mar 18:2023.03.17.533015. doi: 10.1101/2023.03.17.533015. Preprint. PubMed |
| Zn2+ decoration of microtubules arrests axonal transport and displaces tau, doublecortin, and MAP2C. Minckley TF, Salvagio LA, Fudge DH, Verhey K, Markus SM, Qin Y. J Cell Biol. 2023 Aug 7;222(8):e202208121. doi: 10.1083/jcb.202208121. Epub 2023 Jun 16. PubMed |
| A luminescence-based reporter to study tau secretion reveals overlapping mechanisms for the release of healthy and pathological tau. Lopez DM, Maltby CJ, Warming H, Divecha N, Vargas-Caballero M, Coldwell MJ, Deinhardt K. Front Neurosci. 2023 Jun 5;17:1196007. doi: 10.3389/fnins.2023.1196007. eCollection 2023. PubMed |
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