pHAGE TRE dCas9-KRAB Citations (27)
Originally described in: Cas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells.Kearns NA, Genga RM, Enuameh MS, Garber M, Wolfe SA, Maehr R Development. 2014 Jan;141(1):219-23. doi: 10.1242/dev.103341. PubMed Journal
Articles Citing pHAGE TRE dCas9-KRAB
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Transcriptional Regulation with CRISPR/Cas9 Effectors in Mammalian Cells.
Pham H, Kearns NA, Maehr R.
Methods Mol Biol. 2016;1358:43-57. doi: 10.1007/978-1-4939-3067-8_3.
PubMed
Associated Plasmids |
| Controlling transcription in human pluripotent stem cells using CRISPR-effectors. Genga RM, Kearns NA, Maehr R. Methods. 2015 Oct 23. pii: S1046-2023(15)30132-8. doi: 10.1016/j.ymeth.2015.10.014. PubMed |
| Novel Small-Molecule CX3CR1 Antagonist Impairs Metastatic Seeding and Colonization of Breast Cancer Cells. Shen F, Zhang Y, Jernigan DL, Feng X, Yan J, Garcia FU, Meucci O, Salvino JM, Fatatis A. Mol Cancer Res. 2016 Jun;14(6):518-27. doi: 10.1158/1541-7786.MCR-16-0013. Epub 2016 Mar 21. PubMed |
Evaluating Synthetic Activation and Repression of Neuropsychiatric-Related Genes in hiPSC-Derived NPCs, Neurons, and Astrocytes.
Ho SM, Hartley BJ, Flaherty E, Rajarajan P, Abdelaal R, Obiorah I, Barretto N, Muhammad H, Phatnani HP, Akbarian S, Brennand KJ.
Stem Cell Reports. 2017 Aug 8;9(2):615-628. doi: 10.1016/j.stemcr.2017.06.012. Epub 2017 Jul 27.
PubMed
Associated Plasmids |
| The p53-inducible long noncoding RNA TRINGS protects cancer cells from necrosis under glucose starvation. Khan MR, Xiang S, Song Z, Wu M. EMBO J. 2017 Dec 1;36(23):3483-3500. doi: 10.15252/embj.201696239. Epub 2017 Oct 18. PubMed |
| Dismissal of RNA Polymerase II Underlies a Large Ligand-Induced Enhancer Decommissioning Program. Tan Y, Jin C, Ma W, Hu Y, Tanasa B, Oh S, Gamliel A, Ma Q, Yao L, Zhang J, Ohgi K, Liu W, Aggarwal AK, Rosenfeld MG. Mol Cell. 2018 Aug 16;71(4):526-539.e8. doi: 10.1016/j.molcel.2018.07.039. PubMed |
| Quantitative proteomics analysis identifies MUC1 as an effect sensor of EGFR inhibition. de Boer HR, Pool M, Joosten E, Everts M, Samplonius DF, Helfrich W, Groen HJM, van Cooten S, Fusetti F, Fehrmann RSN, de Vries EGE, van Vugt MATM. Oncogene. 2019 Feb;38(9):1477-1488. doi: 10.1038/s41388-018-0522-7. Epub 2018 Oct 10. PubMed |
| The lncRNA TP73-AS1 is linked to aggressiveness in glioblastoma and promotes temozolomide resistance in glioblastoma cancer stem cells. Mazor G, Levin L, Picard D, Ahmadov U, Caren H, Borkhardt A, Reifenberger G, Leprivier G, Remke M, Rotblat B. Cell Death Dis. 2019 Mar 13;10(3):246. doi: 10.1038/s41419-019-1477-5. PubMed |
| SIGMAR1/Sigma-1 receptor ablation impairs autophagosome clearance. Yang H, Shen H, Li J, Guo LW. Autophagy. 2019 Sep;15(9):1539-1557. doi: 10.1080/15548627.2019.1586248. Epub 2019 Mar 14. PubMed |
A piggyBac-based toolkit for inducible genome editing in mammalian cells.
Schertzer MD, Thulson E, Braceros KCA, Lee DM, Hinkle ER, Murphy RM, Kim SO, Vitucci EM, Calabrese JM.
RNA. 2019 May 17. pii: rna.068932.118. doi: 10.1261/rna.068932.118.
PubMed
Associated Plasmids |
| A Yeast Suppressor Screen Used To Identify Mammalian SIRT1 as a Proviral Factor for Middle East Respiratory Syndrome Coronavirus Replication. Weston S, Matthews KL, Lent R, Vlk A, Haupt R, Kingsbury T, Frieman MB. J Virol. 2019 Jul 30;93(16). pii: JVI.00197-19. doi: 10.1128/JVI.00197-19. Print 2019 Aug 15. PubMed |
| Chromatin Remodeling in Response to BRCA2-Crisis. Gruber JJ, Chen J, Geller B, Jager N, Lipchik AM, Wang G, Kurian AW, Ford JM, Snyder MP. Cell Rep. 2019 Aug 20;28(8):2182-2193.e6. doi: 10.1016/j.celrep.2019.07.057. PubMed |
| Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes. Musa J, Cidre-Aranaz F, Aynaud MM, Orth MF, Knott MML, Mirabeau O, Mazor G, Varon M, Holting TLB, Grossetete S, Gartlgruber M, Surdez D, Gerke JS, Ohmura S, Marchetto A, Dallmayer M, Baldauf MC, Stein S, Sannino G, Li J, Romero-Perez L, Westermann F, Hartmann W, Dirksen U, Gymrek M, Anderson ND, Shlien A, Rotblat B, Kirchner T, Delattre O, Grunewald TGP. Nat Commun. 2019 Sep 11;10(1):4128. doi: 10.1038/s41467-019-12071-2. PubMed |
| Functional Enhancers Shape Extrachromosomal Oncogene Amplifications. Morton AR, Dogan-Artun N, Faber ZJ, MacLeod G, Bartels CF, Piazza MS, Allan KC, Mack SC, Wang X, Gimple RC, Wu Q, Rubin BP, Shetty S, Angers S, Dirks PB, Sallari RC, Lupien M, Rich JN, Scacheri PC. Cell. 2019 Nov 27;179(6):1330-1341.e13. doi: 10.1016/j.cell.2019.10.039. Epub 2019 Nov 21. PubMed |
| Integrin alpha-5 subunit is critical for the early stages of human pluripotent stem cell cardiac differentiation. Neiman G, Scarafia MA, La Greca A, Santin Velazque NL, Garate X, Waisman A, Mobbs AM, Kasai-Brunswick TH, Mesquita F, Martire-Greco D, Moro LN, Luzzani C, Bastos Carvalho A, Sevlever GE, Campos de Carvalho A, Guberman AS, Miriuka SG. Sci Rep. 2019 Dec 2;9(1):18077. doi: 10.1038/s41598-019-54352-2. PubMed |
| The PAX-SIX-EYA-DACH network modulates GATA-FOG function in fly hematopoiesis and human erythropoiesis. Creed TM, Baldeosingh R, Eberly CL, Schlee CS, Kim M, Cutler JA, Pandey A, Civin CI, Fossett NG, Kingsbury TJ. Development. 2020 Jan 3;147(1). pii: dev.177022. doi: 10.1242/dev.177022. PubMed |
| Specificity and application of SOX2 antibody. Wei L, Wang L, Pan J, Liu L, Wang P, Wei J, Xu X, Xing Q, Liu P, Wu W, Li G, Zheng X. Poult Sci. 2020 May;99(5):2385-2394. doi: 10.1016/j.psj.2020.01.001. Epub 2020 Mar 20. PubMed |
| Generation of Inducible CRISPRi and CRISPRa Human Stromal/Stem Cell Lines for Controlled Target Gene Transcription during Lineage Differentiation. Chen L, Shi K, Qiu W, Aagaard L, Kassem M. Stem Cells Int. 2020 Aug 19;2020:8857344. doi: 10.1155/2020/8857344. eCollection 2020. PubMed |
| Generation and validation of versatile inducible CRISPRi embryonic stem cell and mouse model. Li R, Xia X, Wang X, Sun X, Dai Z, Huo D, Zheng H, Xiong H, He A, Wu X. PLoS Biol. 2020 Nov 30;18(11):e3000749. doi: 10.1371/journal.pbio.3000749. eCollection 2020 Nov. PubMed |
| RNA m(6)A modification orchestrates a LINE-1-host interaction that facilitates retrotransposition and contributes to long gene vulnerability. Xiong F, Wang R, Lee JH, Li S, Chen SF, Liao Z, Hasani LA, Nguyen PT, Zhu X, Krakowiak J, Lee DF, Han L, Tsai KL, Liu Y, Li W. Cell Res. 2021 Aug;31(8):861-885. doi: 10.1038/s41422-021-00515-8. Epub 2021 Jun 9. PubMed |
| TP73-AS1 is induced by YY1 during TMZ treatment and highly expressed in the aging brain. Mazor G, Smirnov D, Ben David H, Khrameeva E, Toiber D, Rotblat B. Aging (Albany NY). 2021 Jun 11;13(11):14843-14861. doi: 10.18632/aging.203182. Epub 2021 Jun 11. PubMed |
| Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer. Li J, Ohmura S, Marchetto A, Orth MF, Imle R, Dallmayer M, Musa J, Knott MML, Holting TLB, Stein S, Funk CM, Sastre A, Alonso J, Bestvater F, Kasan M, Romero-Perez L, Hartmann W, Ranft A, Banito A, Dirksen U, Kirchner T, Cidre-Aranaz F, Grunewald TGP. Nat Commun. 2021 Sep 16;12(1):5356. doi: 10.1038/s41467-021-25553-z. PubMed |
| CpG island reconfiguration for the establishment and synchronization of polycomb functions upon exit from naive pluripotency. Huo D, Yu Z, Li R, Gong M, Sidoli S, Lu X, Hou Y, Dai Z, Kong Y, Liu G, Jensen ON, Xie W, Helin K, Xiong C, Li G, Zhang Y, Wu X. Mol Cell. 2022 Mar 17;82(6):1169-1185.e7. doi: 10.1016/j.molcel.2022.01.027. Epub 2022 Feb 23. PubMed |
| Evidence against the Human Metapneumovirus G, SH, and M2-2 Proteins as Bona Fide Interferon Antagonists. Groen K, van Nieuwkoop S, Lamers MM, Fouchier RAM, van den Hoogen BG. J Virol. 2022 Sep 14;96(17):e0072322. doi: 10.1128/jvi.00723-22. Epub 2022 Aug 17. PubMed |
| A translational genomics approach identifies IL10RB as the top candidate gene target for COVID-19 susceptibility. Voloudakis G, Vicari JM, Venkatesh S, Hoffman GE, Dobrindt K, Zhang W, Beckmann ND, Higgins CA, Argyriou S, Jiang S, Hoagland D, Gao L, Corvelo A, Cho K, Lee KM, Bian J, Lee JS, Iyengar SK, Luoh SW, Akbarian S, Striker R, Assimes TL, Schadt EE, Lynch JA, Merad M, tenOever BR, Charney AW, Brennand KJ, Fullard JF, Roussos P. NPJ Genom Med. 2022 Sep 5;7(1):52. doi: 10.1038/s41525-022-00324-x. PubMed |
The HASTER lncRNA promoter is a cis-acting transcriptional stabilizer of HNF1A.
Beucher A, Miguel-Escalada I, Balboa D, De Vas MG, Maestro MA, Garcia-Hurtado J, Bernal A, Gonzalez-Franco R, Vargiu P, Heyn H, Ravassard P, Ortega S, Ferrer J.
Nat Cell Biol. 2022 Oct 6. pii: 10.1038/s41556-022-00996-8. doi: 10.1038/s41556-022-00996-8.
PubMed
Associated Plasmids |
| Oncogenic YAP mediates changes in chromatin accessibility and activity that drive cell cycle gene expression and cell migration. Fetiva MC, Liss F, Gertzmann D, Thomas J, Gantert B, Vogl M, Sira N, Weinstock G, Kneitz S, Ade CP, Gaubatz S. Nucleic Acids Res. 2023 May 22;51(9):4266-4283. doi: 10.1093/nar/gkad107. PubMed |
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