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pAAVS1-TLR targeting vector Citations (3)

Plasmid Article: Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells.
Chu VT, Weber T, Wefers B, Wurst W, Sander S, Rajewsky K, Kuhn R Nat Biotechnol. 2015 Mar 24. doi: 10.1038/nbt.3198.
PubMed Journal

Articles Citing pAAVS1-TLR targeting vector

Enhancement of Precise Gene Editing by the Association of Cas9 With Homologous Recombination Factors. Tran NT, Bashir S, Li X, Rossius J, Chu VT, Rajewsky K, Kuhn R. Front Genet. 2019 Apr 30;10:365. doi: 10.3389/fgene.2019.00365. eCollection 2019. PubMed
CRISPR-Cas9 fusion to dominant-negative 53BP1 enhances HDR and inhibits NHEJ specifically at Cas9 target sites. Jayavaradhan R, Pillis DM, Goodman M, Zhang F, Zhang Y, Andreassen PR, Malik P. Nat Commun. 2019 Jun 28;10(1):2866. doi: 10.1038/s41467-019-10735-7. PubMed

Associated Plasmids

Comprehensive Analysis of Genomic Safe Harbors as Target Sites for Stable Expression of the Heterologous Gene in HEK293 Cells. Shin S, Kim SH, Shin SW, Grav LM, Pedersen LE, Lee JS, Lee GM. ACS Synth Biol. 2020 Jun 19;9(6):1263-1269. doi: 10.1021/acssynbio.0c00097. Epub 2020 Jun 2. PubMed

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