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AAV_NLS-dSaCas9-NLS-VPR Citations (7)

Originally described in: Cas9 gRNA engineering for genome editing, activation and repression.
Kiani S, Chavez A, Tuttle M, Hall RN, Chari R, Ter-Ovanesyan D, Qian J, Pruitt BW, Beal J, Vora S, Buchthal J, Kowal EJ, Ebrahimkhani MR, Collins JJ, Weiss R, Church G Nat Methods. 2015 Sep 7. doi: 10.1038/nmeth.3580. PubMed Journal

Articles Citing AAV_NLS-dSaCas9-NLS-VPR

Articles
CRISPR-mediated activation of a promoter or enhancer rescues obesity caused by haploinsufficiency. Matharu N, Rattanasopha S, Tamura S, Maliskova L, Wang Y, Bernard A, Hardin A, Eckalbar WL, Vaisse C, Ahituv N. Science. 2018 Dec 13. pii: science.aau0629. doi: 10.1126/science.aau0629. PubMed

Associated Plasmids
Creation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing. Haldeman JM, Conway AE, Arlotto ME, Slentz DH, Muoio DM, Becker TC, Newgard CB. Nucleic Acids Res. 2018 Dec 27. pii: 5264291. doi: 10.1093/nar/gky1286. PubMed

Associated Plasmids
A Simple Cloning-free Method to Efficiently Induce Gene Expression Using CRISPR/Cas9. Fang L, Hung SSC, Yek J, El Wazan L, Nguyen T, Khan S, Lim SY, Hewitt AW, Wong RCB. Mol Ther Nucleic Acids. 2019 Mar 1;14:184-191. doi: 10.1016/j.omtn.2018.11.008. Epub 2018 Nov 20. PubMed
Targeted Chromatinization and Repression of HIV-1 Provirus Transcription with Repurposed CRISPR/Cas9. Olson A, Basukala B, Lee S, Gagne M, Wong WW, Henderson AJ. Viruses. 2020 Oct 12;12(10). pii: v12101154. doi: 10.3390/v12101154. PubMed
Targeted regulation of transcription in primary cells using CRISPRa and CRISPRi. Jensen TI, Mikkelsen NS, Gao Z, Fosselteder J, Pabst G, Axelgaard E, Laustsen A, Konig S, Reinisch A, Bak RO. Genome Res. 2021 Nov;31(11):2120-2130. doi: 10.1101/gr.275607.121. Epub 2021 Aug 18. PubMed

Associated Plasmids
Molecular basis of FAAH-OUT-associated human pain insensitivity. Mikaeili H, Habib AM, Yeung CW, Santana-Varela S, Luiz AP, Panteleeva K, Zuberi S, Athanasiou-Fragkouli A, Houlden H, Wood JN, Okorokov AL, Cox JJ. Brain. 2023 Sep 1;146(9):3851-3865. doi: 10.1093/brain/awad098. PubMed
Immunomodulation of the donor lung with CRISPR-mediated activation of IL-10 expression. Mesaki K, Juvet S, Yeung J, Guan Z, Wilson GW, Hu J, Davidson AR, Kleinstiver BP, Cypel M, Liu M, Keshavjee S. J Heart Lung Transplant. 2023 Jun 12:S1053-2498(23)01895-8. doi: 10.1016/j.healun.2023.06.001. PubMed

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