Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

pCAG-scFvGCN4sfGFPTET1CD Citations (12)

Originally described in: Targeted DNA demethylation in vivo using dCas9-peptide repeat and scFv-TET1 catalytic domain fusions.
Morita S, Noguchi H, Horii T, Nakabayashi K, Kimura M, Okamura K, Sakai A, Nakashima H, Hata K, Nakashima K, Hatada I Nat Biotechnol. 2016 Aug 29. doi: 10.1038/nbt.3658.
PubMed Journal

Articles Citing pCAG-scFvGCN4sfGFPTET1CD

Articles
TET-mediated epimutagenesis of the Arabidopsis thaliana methylome. Ji L, Jordan WT, Shi X, Hu L, He C, Schmitz RJ. Nat Commun. 2018 Mar 1;9(1):895. doi: 10.1038/s41467-018-03289-7. PubMed
Editing of DNA Methylation Using dCas9-Peptide Repeat and scFv-TET1 Catalytic Domain Fusions. Morita S, Horii T, Hatada I. Methods Mol Biol. 2018;1767:419-428. doi: 10.1007/978-1-4939-7774-1_23. PubMed
CRISPR-Based Targeted Epigenetic Editing Enables Gene Expression Modulation of the Silenced Beta-Galactoside Alpha-2,6-Sialyltransferase 1 in CHO Cells. Marx N, Grunwald-Gruber C, Bydlinski N, Dhiman H, Ngoc Nguyen L, Klanert G, Borth N. Biotechnol J. 2018 Oct;13(10):e1700217. doi: 10.1002/biot.201700217. Epub 2018 Jun 11. PubMed
MICMIC: identification of DNA methylation of distal regulatory regions with causal effects on tumorigenesis. Tong Y, Sun J, Wong CF, Kang Q, Ru B, Wong CN, Chan AS, Leung SY, Zhang J. Genome Biol. 2018 Jun 5;19(1):73. doi: 10.1186/s13059-018-1442-0. PubMed
Repression of TERRA Expression by Subtelomeric DNA Methylation Is Dependent on NRF1 Binding. Le Berre G, Hossard V, Riou JF, Guieysse-Peugeot AL. Int J Mol Sci. 2019 Jun 7;20(11). pii: ijms20112791. doi: 10.3390/ijms20112791. PubMed
Enhanced CRISPR-based DNA demethylation by Casilio-ME-mediated RNA-guided coupling of methylcytosine oxidation and DNA repair pathways. Taghbalout A, Du M, Jillette N, Rosikiewicz W, Rath A, Heinen CD, Li S, Cheng AW. Nat Commun. 2019 Sep 20;10(1):4296. doi: 10.1038/s41467-019-12339-7. PubMed

Associated Plasmids

Successful generation of epigenetic disease model mice by targeted demethylation of the epigenome. Horii T, Morita S, Hino S, Kimura M, Hino Y, Kogo H, Nakao M, Hatada I. Genome Biol. 2020 Apr 1;21(1):77. doi: 10.1186/s13059-020-01991-8. PubMed
TALE.Sense: A Versatile DNA Sensor Platform for Live Mammalian Cells. Taghbalout A, Jillette N, Cheng AW. ACS Synth Biol. 2022 Jan 21;11(1):116-124. doi: 10.1021/acssynbio.1c00212. Epub 2021 Dec 21. PubMed
Epigenome editing reveals core DNA methylation for imprinting control in the Dlk1-Dio3 imprinted domain. Kojima S, Shiochi N, Sato K, Yamaura M, Ito T, Yamamura N, Goto N, Odamoto M, Kobayashi S, Kimura T, Sekita Y. Nucleic Acids Res. 2022 May 20;50(9):5080-5094. doi: 10.1093/nar/gkac344. PubMed
The microRNA cluster C19MC confers differentiation potential into trophoblast lineages upon human pluripotent stem cells. Kobayashi N, Okae H, Hiura H, Kubota N, Kobayashi EH, Shibata S, Oike A, Hori T, Kikutake C, Hamada H, Kaji H, Suyama M, Bortolin-Cavaille ML, Cavaille J, Arima T. Nat Commun. 2022 Jun 2;13(1):3071. doi: 10.1038/s41467-022-30775-w. PubMed
Genome-wide DNA hypermethylation opposes healing in patients with chronic wounds by impairing epithelial-mesenchymal transition. Singh K, Rustagi Y, Abouhashem AS, Tabasum S, Verma P, Hernandez E, Pal D, Khona DK, Mohanty SK, Kumar M, Srivastava R, Guda PR, Verma SS, Mahajan S, Killian JA, Walker LA, Ghatak S, Mathew-Steiner SS, Wanczyk KE, Liu S, Wan J, Yan P, Bundschuh R, Khanna S, Gordillo GM, Murphy MP, Roy S, Sen CK. J Clin Invest. 2022 Sep 1;132(17):e157279. doi: 10.1172/JCI157279. PubMed
Activation of stably silenced genes by recruitment of a synthetic de-methylating module. Chan WF, Coughlan HD, Chen Y, Keenan CR, Smyth GK, Perkins AC, Johanson TM, Allan RS. Nat Commun. 2022 Sep 23;13(1):5582. doi: 10.1038/s41467-022-33181-4. PubMed

Associated Plasmids

If you have published an article using this material, please email us at [email protected] to have your article added to this page.