Fuw-dCas9-Tet1CD Citations (15)
Originally described in: Editing DNA Methylation in the Mammalian Genome.Liu XS, Wu H, Ji X, Stelzer Y, Wu X, Czauderna S, Shu J, Dadon D, Young RA, Jaenisch R Cell. 2016 Sep 22;167(1):233-247.e17. doi: 10.1016/j.cell.2016.08.056. PubMed Journal
Articles Citing Fuw-dCas9-Tet1CD
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| New variants of CRISPR RNA-guided genome editing enzymes. Murovec J, Pirc Z, Yang B. Plant Biotechnol J. 2017 Aug;15(8):917-926. doi: 10.1111/pbi.12736. Epub 2017 May 9. PubMed |
| CRISPR-Mediated Reactivation of DKK3 Expression Attenuates TGF-beta Signaling in Prostate Cancer. Kardooni H, Gonzalez-Gualda E, Stylianakis E, Saffaran S, Waxman J, Kypta RM. Cancers (Basel). 2018 May 28;10(6). pii: cancers10060165. doi: 10.3390/cancers10060165. PubMed |
| Inactivation of SMARCA2 by promoter hypermethylation drives lung cancer development. Wu J, He K, Zhang Y, Song J, Shi Z, Chen W, Shao Y. Gene. 2019 Mar 1;687:193-199. doi: 10.1016/j.gene.2018.11.032. Epub 2018 Nov 14. PubMed |
| Functional methylome analysis of human diabetic kidney disease. Park J, Guan Y, Sheng X, Gluck C, Seasock MJ, Hakimi AA, Qiu C, Pullman J, Verma A, Li H, Palmer M, Susztak K. JCI Insight. 2019 Jun 6;4(11). pii: 128886. doi: 10.1172/jci.insight.128886. eCollection 2019 Jun 6. PubMed |
| Tet inactivation disrupts YY1 binding and long-range chromatin interactions during embryonic heart development. Fang S, Li J, Xiao Y, Lee M, Guo L, Han W, Li T, Hill MC, Hong T, Mo W, Xu R, Zhang P, Wang F, Chang J, Zhou Y, Sun D, Martin JF, Huang Y. Nat Commun. 2019 Sep 20;10(1):4297. doi: 10.1038/s41467-019-12325-z. PubMed |
| Silencing of the TRIM58 Gene by Aberrant Promoter Methylation is Associated with a Poor Patient Outcome and Promotes Cell Proliferation and Migration in Clear Cell Renal Cell Carcinoma. Gan Y, Cao C, Li A, Song H, Kuang G, Ma B, Zhang Q, Zhang Q. Front Mol Biosci. 2021 Mar 16;8:655126. doi: 10.3389/fmolb.2021.655126. eCollection 2021. PubMed |
Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing.
Nunez JK, Chen J, Pommier GC, Cogan JZ, Replogle JM, Adriaens C, Ramadoss GN, Shi Q, Hung KL, Samelson AJ, Pogson AN, Kim JYS, Chung A, Leonetti MD, Chang HY, Kampmann M, Bernstein BE, Hovestadt V, Gilbert LA, Weissman JS.
Cell. 2021 Apr 7. pii: S0092-8674(21)00353-6. doi: 10.1016/j.cell.2021.03.025.
PubMed
Associated Plasmids |
| Genomic Targeting of TET Activity for Targeted Demethylation Using CRISPR/Cas9. Nguyen TV, Lister R. Methods Mol Biol. 2021;2272:181-194. doi: 10.1007/978-1-0716-1294-1_10. PubMed |
| Locus-Specific DNA Methylation Editing in Melanoma Cell Lines Using a CRISPR-Based System. Smith J, Banerjee R, Waly R, Urbano A, Gimenez G, Day R, Eccles MR, Weeks RJ, Chatterjee A. Cancers (Basel). 2021 Oct 29;13(21). pii: cancers13215433. doi: 10.3390/cancers13215433. PubMed |
| Epigenetic interaction between UTX and DNMT1 regulates diet-induced myogenic remodeling in brown fat. Li F, Jing J, Movahed M, Cui X, Cao Q, Wu R, Chen Z, Yu L, Pan Y, Shi H, Shi H, Xue B. Nat Commun. 2021 Nov 25;12(1):6838. doi: 10.1038/s41467-021-27141-7. PubMed |
| Hypomethylation-activated cancer-testis gene LIN28B promotes cell proliferation and metastasis in gastric cancer. Xu J, Zhou Y, Yang J, Gu Y, Zhang E, Yuan W, Wang C, Jin G, Ma H, Hu Z. Gene. 2022 Mar 1;813:146115. doi: 10.1016/j.gene.2021.146115. Epub 2021 Dec 10. PubMed |
| Epigenetic reprogramming by TET enzymes impacts co-transcriptional R-loops. Sabino JC, de Almeida MR, Abreu PL, Ferreira AM, Caldas P, Domingues MM, Santos NC, Azzalin CM, Grosso AR, de Almeida SF. Elife. 2022 Feb 22;11. pii: 69476. doi: 10.7554/eLife.69476. PubMed |
| The identification and validation of EphA7 hypermethylation, a novel biomarker, in cervical cancer. Zhang W, Cao H, Yang J, Zhao J, Liang Z, Kang X, Wang R. BMC Cancer. 2022 Jun 9;22(1):636. doi: 10.1186/s12885-022-09653-7. PubMed |
| THOR is a targetable epigenetic biomarker with clinical implications in breast cancer. Apolonio JD, Dias JS, Fernandes MT, Komosa M, Lipman T, Zhang CH, Leao R, Lee D, Nunes NM, Maia AT, Morera JL, Vicioso L, Tabori U, Castelo-Branco P. Clin Epigenetics. 2022 Dec 18;14(1):178. doi: 10.1186/s13148-022-01396-3. PubMed |
| Epigenetic reactivation of tumor suppressor genes with CRISPRa technologies as precision therapy for hepatocellular carcinoma. Sgro A, Cursons J, Waryah C, Woodward EA, Foroutan M, Lyu R, Yeoh GCT, Leedman PJ, Blancafort P. Clin Epigenetics. 2023 Apr 29;15(1):73. doi: 10.1186/s13148-023-01482-0. PubMed |
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