Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

Addgene

pcDNA3-HA-ERK2 WT Citations (15)

Originally described in: Spatially separate docking sites on ERK2 regulate distinct signaling events in vivo.
Dimitri CA, Dowdle W, MacKeigan JP, Blenis J, Murphy LO Curr Biol. 2005 Jul 26. 15(14):1319-24.
PubMed Journal

Articles Citing pcDNA3-HA-ERK2 WT

Articles
A high-throughput assay for phosphoprotein-specific phosphatase activity in cellular extracts. Bose AK, Janes KA. Mol Cell Proteomics. 2013 Mar;12(3):797-806. doi: 10.1074/mcp.O112.024059. Epub 2012 Dec 11. PubMed

Associated Plasmids

Extracellular signal-regulated kinase and glycogen synthase kinase 3beta regulate gephyrin postsynaptic aggregation and GABAergic synaptic function in a calpain-dependent mechanism. Tyagarajan SK, Ghosh H, Yevenes GE, Imanishi SY, Zeilhofer HU, Gerrits B, Fritschy JM. J Biol Chem. 2013 Apr 5;288(14):9634-47. doi: 10.1074/jbc.M112.442616. Epub 2013 Feb 13. PubMed

Associated Plasmids

MicroRNA-21 promotes the proliferation and inhibits apoptosis in Eca109 via activating ERK1/2/MAPK pathway. Liu F, Zheng S, Liu T, Liu Q, Liang M, Li X, Sheyhidin I, Lu X, Liu W. Mol Cell Biochem. 2013 Sep;381(1-2):115-25. doi: 10.1007/s11010-013-1693-8. Epub 2013 May 25. PubMed
Autophagy proteins regulate ERK phosphorylation. Martinez-Lopez N, Athonvarangkul D, Mishall P, Sahu S, Singh R. Nat Commun. 2013;4:2799. doi: 10.1038/ncomms3799. PubMed
ERK/MAPK regulates ERRgamma expression, transcriptional activity, and receptor-mediated Tamoxifen resistance in ER+ breast cancer. Heckler MM, Thakor H, Schafer CC, Riggins RB. FEBS J. 2014 Mar 29. doi: 10.1111/febs.12797. PubMed

Associated Plasmids

Extracellular signal-regulated kinase activation during cardiac hypertrophy reduces sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) transcription. Huang H, Joseph LC, Gurin MI, Thorp EB, Morrow JP. J Mol Cell Cardiol. 2014 Oct;75:58-63. doi: 10.1016/j.yjmcc.2014.06.018. Epub 2014 Jul 6. PubMed
CCAAT/enhancer binding protein beta regulates the expression of tumor necrosis factor-alpha in the nucleus pulposus cells. Hiyama A, Hiraishi S, Sakai D, Mochida J. J Orthop Res. 2015 Oct 27. doi: 10.1002/jor.23085. PubMed
The histone demethylase PHF8 is a molecular safeguard of the IFNgamma response. Asensio-Juan E, Fueyo R, Pappa S, Iacobucci S, Badosa C, Lois S, Balada M, Bosch-Presegue L, Vaquero A, Gutierrez S, Caelles C, Gallego C, de la Cruz X, Martinez-Balbas MA. Nucleic Acids Res. 2017 Apr 20;45(7):3800-3811. doi: 10.1093/nar/gkw1346. PubMed
Stimulus-evoked ERK-dependent phosphorylation of activity-regulated cytoskeleton-associated protein (Arc) regulates its neuronal subcellular localization. Nikolaienko O, Eriksen MS, Patil S, Bito H, Bramham CR. Neuroscience. 2017 Sep 30;360:68-80. doi: 10.1016/j.neuroscience.2017.07.026. Epub 2017 Jul 21. PubMed
CCN family member 2/connective tissue growth factor (CCN2/CTGF) is regulated by Wnt-beta-catenin signaling in nucleus pulposus cells. Hiyama A, Morita K, Sakai D, Watanabe M. Arthritis Res Ther. 2018 Sep 29;20(1):217. doi: 10.1186/s13075-018-1723-8. PubMed
CIC protein instability contributes to tumorigenesis in glioblastoma. Bunda S, Heir P, Metcalf J, Li ASC, Agnihotri S, Pusch S, Yasin M, Li M, Burrell K, Mansouri S, Singh O, Wilson M, Alamsahebpour A, Nejad R, Choi B, Kim D, von Deimling A, Zadeh G, Aldape K. Nat Commun. 2019 Feb 8;10(1):661. doi: 10.1038/s41467-018-08087-9. PubMed
c-Src Phosphorylates and Inhibits the Function of the CIC Tumor Suppressor Protein. Bunda S, Heir P, Li ASC, Mamatjan Y, Zadeh G, Aldape K. Mol Cancer Res. 2020 May;18(5):774-786. doi: 10.1158/1541-7786.MCR-18-1370. Epub 2020 Feb 6. PubMed
High Expression of Integrin alpha3 Predicts Poor Prognosis and Promotes Tumor Metastasis and Angiogenesis by Activating the c-Src/Extracellular Signal-Regulated Protein Kinase/Focal Adhesion Kinase Signaling Pathway in Cervical Cancer. Du Q, Wang W, Liu T, Shang C, Huang J, Liao Y, Qin S, Chen Y, Liu P, Liu J, Yao S. Front Oncol. 2020 Feb 14;10:36. doi: 10.3389/fonc.2020.00036. eCollection 2020. PubMed
H2O2 mediated FLIP and XIAP down-regulation involves increased ITCH expression and ERK-Akt crosstalk in imatinib resistant Chronic Myeloid Leukemia cell line K562. Paul T, Roy R, Sarkar RD, Sinha S, Biswas N. Free Radic Biol Med. 2021 Apr;166:265-276. doi: 10.1016/j.freeradbiomed.2021.02.024. Epub 2021 Feb 22. PubMed
Sublytic C5b-9 induces glomerular mesangial cell proliferation via ERK1/2-dependent SOX9 phosphorylation and acetylation by enhancing Cyclin D1 in rat Thy-1 nephritis. Xie M, Wu Z, Ying S, Liu L, Zhao C, Yao C, Zhang Z, Luo C, Wang W, Zhao D, Zhang J, Qiu W, Wang Y. Exp Mol Med. 2021 Apr;53(4):572-590. doi: 10.1038/s12276-021-00589-9. Epub 2021 Apr 2. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.