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pLEX_305-C-dTAG Citations (6)

Originally described in: The dTAG system for immediate and target-specific protein degradation.
Nabet B, Roberts JM, Buckley DL, Paulk J, Dastjerdi S, Yang A, Leggett AL, Erb MA, Lawlor MA, Souza A, Scott TG, Vittori S, Perry JA, Qi J, Winter GE, Wong KK, Gray NS, Bradner JE Nat Chem Biol. 2018 May;14(5):431-441. doi: 10.1038/s41589-018-0021-8. Epub 2018 Mar 26.
PubMed Journal

Articles Citing pLEX_305-C-dTAG

Articles
Selective Modulation of a Pan-Essential Protein as a Therapeutic Strategy in Cancer. Malone CF, Dharia NV, Kugener G, Forman AB, Rothberg MV, Abdusamad M, Gonzalez A, Kuljanin M, Robichaud AL, Conway AS, Dempster JM, Paolella BR, Dumont N, Hovestadt V, Mancias JD, Younger ST, Root DE, Golub TR, Vazquez F, Stegmaier K. Cancer Discov. 2021 Sep;11(9):2282-2299. doi: 10.1158/2159-8290.CD-20-1213. Epub 2021 Apr 21. PubMed
VRK1 as a synthetic lethal target in VRK2 promoter-methylated cancers of the nervous system. So J, Mabe NW, Englinger B, Chow KH, Moyer SM, Yerrum S, Trissal MC, Marques JG, Kwon JJ, Shim B, Pal S, Panditharatna E, Quinn T, Schaefer DA, Jeong D, Mayhew DL, Hwang J, Beroukhim R, Ligon KL, Stegmaier K, Filbin MG, Hahn WC. JCI Insight. 2022 Oct 10;7(19):e158755. doi: 10.1172/jci.insight.158755. PubMed

Associated Plasmids

The ETS transcription factor ETV6 constrains the transcriptional activity of EWS-FLI to promote Ewing sarcoma. Lu DY, Ellegast JM, Ross KN, Malone CF, Lin S, Mabe NW, Dharia NV, Meyer A, Conway A, Su AH, Selich-Anderson J, Taslim C, Byrum AK, Seong BKA, Adane B, Gray NS, Rivera MN, Lessnick SL, Stegmaier K. Nat Cell Biol. 2023 Feb;25(2):285-297. doi: 10.1038/s41556-022-01059-8. Epub 2023 Jan 19. PubMed
Recovery of protein synthesis to assay DNA repair activity in transcribed genes in living cells and tissues. van der Woude M, Davo-Martinez C, Thijssen KL, Vermeulen W, Lans H. Nucleic Acids Res. 2023 Oct 13;51(18):e93. doi: 10.1093/nar/gkad642. PubMed

Associated Plasmids

The SMN complex drives structural changes in human snRNAs to enable snRNP assembly. Panek J, Roithova A, Radivojevic N, Sykora M, Prusty AB, Huston N, Wan H, Pyle AM, Fischer U, Stanek D. Nat Commun. 2023 Oct 18;14(1):6580. doi: 10.1038/s41467-023-42324-0. PubMed
Harnessing PROTAC technology to combat stress hormone receptor activation. Gazorpak M, Hugentobler KM, Paul D, Germain PL, Kretschmer M, Ivanova I, Frei S, Mathis K, Rudolf R, Mompart Barrenechea S, Fischer V, Xue X, Ptaszek AL, Holzinger J, Privitera M, Hierlemann A, Meijer OC, Konrat R, Carreira EM, Bohacek J, Gapp K. Nat Commun. 2023 Dec 9;14(1):8177. doi: 10.1038/s41467-023-44031-2. PubMed

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