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Bernardo Sabatini Lab Plasmids


The Bernardo Sabatini Lab has deposited plasmids at Addgene for distribution to the research community. Addgene is a nonprofit plasmid repository dedicated to improving life science research.

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Title Authors Publication
Recurrent network activity drives striatal synaptogenesis. Kozorovitskiy Y, Saunders A, Johnson CA, Lowell BB, Sabatini BL Nature. 2012 May 13;485(7400):646-50. doi: 10.1038/nature11052.
Novel recombinant adeno-associated viruses for Cre activated and inactivated transgene expression in neurons. Saunders A, Johnson CA and Sabatini BL Front. Neural Circuits 6:47. doi: 10.3389/fncir.2012.00047
Dopaminergic neurons inhibit striatal output through non-canonical release of GABA. Tritsch NX, Ding JB, Sabatini BL. Nature. 2012 Oct 3. doi: 10.1038/nature11466.
A PKA activity sensor for quantitative analysis of endogenous GPCR signaling via 2-photon FRET-FLIM imaging. Chen Y, Saulnier JL, Yellen G, Sabatini BL Front Pharmacol. 2014 Apr 2;5:56. doi: 10.3389/fphar.2014.00056. eCollection 2014.
Destabilization of the postsynaptic density by PSD-95 serine 73 phosphorylation inhibits spine growth and synaptic plasticity. Steiner P, Higley MJ, Xu W, Czervionke BL, Malenka RC, Sabatini BL Neuron. 2008 Dec 10;60(5):788-802. doi: 10.1016/j.neuron.2008.10.014.
Central Control Circuit for Context-Dependent Micturition. Hou XH, Hyun M, Taranda J, Huang KW, Todd E, Feng D, Atwater E, Croney D, Zeidel ML, Osten P, Sabatini BL Cell. 2016 Sep 22;167(1):73-86.e12. doi: 10.1016/j.cell.2016.08.073.
ID Plasmid Gene/Insert Vector Type Publication Hidden Extra Search Info  
37082pAAV-Ef1a-DO-hChR2(H134R)-mCherry-WPRE-pAhChr2(H134R)-mCherry (Synthetic)AAV ; rRecurrent network activity drives striatal synaptogenesis. Nature. 2012 May 13;485(7400):646-50. doi: 10.1038/nature11052. pAAV-Ef1a-DIO-hChR2(H134R)-mCherry-WPRE-pA Add to Cart
37083pAAV-Ef1a-DIO-mCherry-WPRE-pAmCherry (Synthetic)rAAVNovel recombinant adeno-associated viruses for Cre activated and inactivated transgene expression in neurons. Front. Neural Circuits 6:47. doi: 10.3389/fncir.2012.00047 pAAV-Ef1a-DIO-hChR2(H134R)-mCherry-WPRE-pA Add to Cart
37084pAAV-Ef1a-DIO-EGFP-WPRE-pAEGFP (Synthetic)rAAVNovel recombinant adeno-associated viruses for Cre activated and inactivated transgene expression in neurons. Front. Neural Circuits 6:47. doi: 10.3389/fncir.2012.00047 pAAV-Ef1a-DIO-hChR2(H134R)-mCherry-WPRE-pA Add to Cart
37085pAAV-Ef1a-DO-EGFP-WPRE-pAEGFP (Synthetic)rAAVNovel recombinant adeno-associated viruses for Cre activated and inactivated transgene expression in neurons. Front. Neural Circuits 6:47. doi: 10.3389/fncir.2012.00047 pAAV-Ef1a-DIO-hChR2(H134R)-mCherry-WPRE-pA Add to Cart
37086pAAV-Ef1a-DO-ChETA-EYFP-WPRE-pAChETA-YFP (Synthetic)rAAVNovel recombinant adeno-associated viruses for Cre activated and inactivated transgene expression in neurons. Front. Neural Circuits 6:47. doi: 10.3389/fncir.2012.00047 pAAV-Ef1a-DIO-hChR2(H134R)-mCherry-WPRE-pA Add to Cart
37087pAAV-Ef1a-DO-NpHR3.0-eYFP-WPRE-pANpHR3.0-EYFP (Synthetic)rAAVNovel recombinant adeno-associated viruses for Cre activated and inactivated transgene expression in neurons. Front. Neural Circuits 6:47. doi: 10.3389/fncir.2012.00047 pAAV-Ef1a-DIO-hChR2(H134R)-mCherry-WPRE-pA
  • Tag / Fusion Protein
    • EYFP (C terminal on insert)
  • Add to Cart
    37088pAAV-Ef1a-FAS-NpHR3.0-eYFP-WPRE-pANpHR3.0-EYFP (Synthetic)rAAVNovel recombinant adeno-associated viruses for Cre activated and inactivated transgene expression in neurons. Front. Neural Circuits 6:47. doi: 10.3389/fncir.2012.00047 pAAV-Ef1a-DIO-hChR2(H134R)-mCherry-WPRE-pA
  • Tag / Fusion Protein
    • EYFP (C terminal on insert)
  • Add to Cart
    37089pAAV-Ef1a-FAS-ChETA-TdTomato-WPRE-pAChETA-TdTomato (Synthetic)AAV ; rNovel recombinant adeno-associated viruses for Cre activated and inactivated transgene expression in neurons. Front. Neural Circuits 6:47. doi: 10.3389/fncir.2012.00047 pAAV-Ef1a-DIO-hChR2(H134R)-mCherry-WPRE-pA
  • Tag / Fusion Protein
    • TdTomato (C terminal on insert)
  • Add to Cart
    37090pAAV-Ef1a-FAS-hChR2(H134R)-mCherry-WPRE-pAhChr2(H134R)-mCherry (Synthetic)rAAVNovel recombinant adeno-associated viruses for Cre activated and inactivated transgene expression in neurons. Front. Neural Circuits 6:47. doi: 10.3389/fncir.2012.00047 pAAV-Ef1a-DIO-hChR2(H134R)-mCherry-WPRE-pA
  • Tag / Fusion Protein
    • mCherry (C terminal on insert)
  • Add to Cart
    37091pAAV-Ef1a-FAS-EGFP-WPRE-pAd1eGFP (Synthetic)rAAVNovel recombinant adeno-associated viruses for Cre activated and inactivated transgene expression in neurons. Front. Neural Circuits 6:47. doi: 10.3389/fncir.2012.00047 pAAV-Ef1a-DIO-hChR2(H134R)-mCherry-WPRE-pA Add to Cart
    37092pAAV-Ef1a-FAS-TdTomato-WPRE-pATdTomato (Synthetic)rAAVNovel recombinant adeno-associated viruses for Cre activated and inactivated transgene expression in neurons. Front. Neural Circuits 6:47. doi: 10.3389/fncir.2012.00047 pAAV-Ef1a-DIO-hChR2(H134R)-mCherry-WPRE-pA Add to Cart
    37119pAAV-Ef1a-DO-mCherry-WPRE-pAmCherry (Synthetic)rAAVNovel recombinant adeno-associated viruses for Cre activated and inactivated transgene expression in neurons. Front. Neural Circuits 6:47. doi: 10.3389/fncir.2012.00047 pAAV-Ef1a-DIO-hChR2(H134R)-mCherry-WPRE-pA Add to Cart
    37120pAAV-Ef1a-DO_DIO-TdTomato_EGFP-WPRE-pATdTomato-EGFP (Synthetic)rAAVNovel recombinant adeno-associated viruses for Cre activated and inactivated transgene expression in neurons. Front. Neural Circuits 6:47. doi: 10.3389/fncir.2012.00047 pAAV-Ef1a-DIO-hChR2(H134R)-mCherry-WPRE-pA Add to Cart
    37755pAAV-Ef1a-DIO-ChETA-TdTomato-WPRE-pAChETA-TdTomato (Synthetic)rAAVNovel recombinant adeno-associated viruses for Cre activated and inactivated transgene expression in neurons. Front. Neural Circuits 6:47. doi: 10.3389/fncir.2012.00047 pAAV-Ef1a-DIO-hChR2(H134R)-mCherry-WPRE-pA
  • Tag / Fusion Protein
    • TdTomato (C terminal on insert)
  • Add to Cart
    37756pAAV-Ef1a-DO-ChETA-TdTomato-WPRE-pAChETA-TdTomato (Synthetic)rAAVNovel recombinant adeno-associated viruses for Cre activated and inactivated transgene expression in neurons. Front. Neural Circuits 6:47. doi: 10.3389/fncir.2012.00047 pAAV-Ef1a-DIO-hChR2(H134R)-mCherry-WPRE-pA
  • Tag / Fusion Protein
    • TdTomato (C terminal on insert)
  • Add to Cart
    39320pAAV-Ef1a-DIO-VGAT-WPRE-pASlc32a1 (Mus musculus)AAV ; rDopaminergic neurons inhibit striatal output through non-canonical release of GABA. Nature. 2012 Oct 3. doi: 10.1038/nature11466. pAAV-Ef1a-DIO-hChR2(H134R)-mCherry-WPRE-pA Slc32a1 R75019, VGAT, Viaat Add to Cart
    39339pAAV-Ef1a-DIO-VMAT2-WPRE-pASlc18a2 (Mus musculus)AAV ; rDopaminergic neurons inhibit striatal output through non-canonical release of GABA. Nature. 2012 Oct 3. doi: 10.1038/nature11466. pAAV-Ef1a-DIO-hChR2(H134R)-mCherry-WPRE-pA Slc18a2 1110037L13Rik, 9330105E13, Vmat2 Add to Cart
    60445AAV-FLEX-FLIM-AKARFLIM-AKAR (Synthetic)Mammalian Expression, AAV, Cre/LoxA PKA activity sensor for quantitative analysis of endogenous GPCR signaling via 2-photon FRET-FLIM imaging. Front Pharmacol. 2014 Apr 2;5:56. doi: 10.3389/fphar.2014.00056. eCollection 2014. Expresses the Fluorescence Lifetime Imaging Microscopy (FLIM)-compatible PKA activity sensor FLIM-AKAR in a Cre dependent manner in an AAV backbone AAV-FLEX Add to Cart
    60446AAV-FLEX-FLIM-AKART391AFLIM-AKART391A (Synthetic)Mammalian Expression, AAV, Cre/LoxA PKA activity sensor for quantitative analysis of endogenous GPCR signaling via 2-photon FRET-FLIM imaging. Front Pharmacol. 2014 Apr 2;5:56. doi: 10.3389/fphar.2014.00056. eCollection 2014. Expresses the non-phosphorylatable point mutant (T391A) of FLIM-AKAR in a Cre dependent manner in an AAV backbone AAV-FLEX Add to Cart
    63058AAV-FLIM-AKARFLIM-AKAR (Synthetic)Mammalian Expression, AAVA PKA activity sensor for quantitative analysis of endogenous GPCR signaling via 2-photon FRET-FLIM imaging. Front Pharmacol. 2014 Apr 2;5:56. doi: 10.3389/fphar.2014.00056. eCollection 2014. Expresses the Fluorescence Lifetime Imaging Microscopy (FLIM)-compatible PKA activity sensor FLIM-AKAR in an AAV backbone AAV-ChR2-mCherry Add to Cart
    63059AAV-FLEX-PKIalpha-IRES-nls-mRuby2PKIalpha (Mus musculus)Mammalian Expression, AAV, Cre/LoxA PKA activity sensor for quantitative analysis of endogenous GPCR signaling via 2-photon FRET-FLIM imaging. Front Pharmacol. 2014 Apr 2;5:56. doi: 10.3389/fphar.2014.00056. eCollection 2014. Expresses PKIalpha and nuclear localized mRuby2 (linked with IRES) in a Cre-dependent manner in an AAV backbone AAV-FLEX-tmeGFP-IRES-nls-mRuby2 Pkia AI415001, PKIalpha Add to Cart
    63060AAV-FLEX-tmeGFP-IRES-nls-mRuby2nls-mRuby2 (Synthetic)Mammalian Expression, AAV, Cre/LoxA PKA activity sensor for quantitative analysis of endogenous GPCR signaling via 2-photon FRET-FLIM imaging. Front Pharmacol. 2014 Apr 2;5:56. doi: 10.3389/fphar.2014.00056. eCollection 2014. Expresses truncated monomeric eGFP and nuclear localized mRuby2 (linked with IRES) in a Cre-dependent manner in an AAV backbone AAV-FLEX-FLIM-AKAR Add to Cart
    74040FH95pUP95S73DGW (F3)Psd95 (Homo sapiens)Mammalian Expression, Lentiviral, RNAiDestabilization of the postsynaptic density by PSD-95 serine 73 phosphorylation inhibits spine growth and synaptic plasticity. Neuron. 2008 Dec 10;60(5):788-802. doi: 10.1016/j.neuron.2008.10.014. lentiviral expression of Psd95 shRNA and Psd95-S73D-EGFP fusion FUGW Add to Cart
    81008pAAV-CBA-DIO-hM4Di-mCherryhM4D(Gi)-mCherryAAVCentral Control Circuit for Context-Dependent Micturition. Cell. 2016 Sep 22;167(1):73-86.e12. doi: 10.1016/j.cell.2016.08.073. Cre-dependent expression of hM4Di-mCherry under CBA promoter pAAV Add to Cart