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Joseph Costello Lab Plasmids


The Joseph Costello Lab has deposited plasmids at Addgene for distribution to the research community. Addgene is a nonprofit plasmid repository dedicated to improving life science research.

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Title Authors Publication
Epigenome scans and cancer genome sequencing converge on WNK2, a kinase-independent suppressor of cell growth. Hong C, Moorefield KS, Jun P, Aldape KD, Kharbanda S, Phillips HS, Costello JF Proc Natl Acad Sci U S A. 2007 Jun 26. 104(26):10974-9.
Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer. Bell RJ, Rube HT, Kreig A, Mancini A, Fouse SD, Nagarajan RP, Choi S, Hong C, He D, Pekmezci M, Wiencke JK, Wrensch MR, Chang SM, Walsh KM, Myong S, Song JS, Costello JF Science. 2015 May 29;348(6238):1036-9. doi: 10.1126/science.aab0015. Epub 2015 May 14.
ID Plasmid Gene/Insert Vector Type Publication Hidden Extra Search Info  
24569WNK2 WTWNK2 (Homo sapiens)Mammalian ExpressionEpigenome scans and cancer genome sequencing converge on WNK2, a kinase-independent suppressor of cell growth. Proc Natl Acad Sci U S A. 2007 Jun 26. 104(26):10974-9. pcDNA3.1/V5–His–TOPO WNK2 PRKWNK2, KIAA1760, NY-CO-43, SDCCAG43, P/OKcl.13 Add to Cart
24570WNK2 K207AWNK2` (Homo sapiens)Mammalian ExpressionEpigenome scans and cancer genome sequencing converge on WNK2, a kinase-independent suppressor of cell growth. Proc Natl Acad Sci U S A. 2007 Jun 26. 104(26):10974-9. pcDNA3.1/V5–His–TOPO WNK2 PRKWNK2, KIAA1760, NY-CO-43, SDCCAG43, P/OKcl.13 Add to Cart
84924pGL4.0-TERT WTTERT promoter (Homo sapiens)Mammalian Expression, LuciferaseCancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer. Science. 2015 May 29;348(6238):1036-9. doi: 10.1126/science.aab0015. Epub 2015 May 14. luciferase reporter for TERT promoter pGL4.0 TERT CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT Add to Cart
84925pGL4.0-TERT G250ATERT promoter (Homo sapiens)Mammalian Expression, LuciferaseCancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer. Science. 2015 May 29;348(6238):1036-9. doi: 10.1126/science.aab0015. Epub 2015 May 14. luciferase reporter for mutant TERT promoter pGL4.0 TERT CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT Add to Cart
84926pGL4.0-TERT G228ATERT promoter (Homo sapiens)Mammalian Expression, LuciferaseCancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer. Science. 2015 May 29;348(6238):1036-9. doi: 10.1126/science.aab0015. Epub 2015 May 14. luciferase reporter for mutant TERT promoter pGL4.0 TERT CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT Add to Cart