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Rene Maehr Lab Plasmids


The Rene Maehr Lab has deposited plasmids at Addgene for distribution to the research community. Addgene is a nonprofit plasmid repository dedicated to improving life science research.

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Title Authors Publication
Cas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells. Kearns NA, Genga RM, Enuameh MS, Garber M, Wolfe SA, Maehr R Development. 2014 Jan;141(1):219-23. doi: 10.1242/dev.103341.
Transcriptional Regulation with CRISPR/Cas9 Effectors in Mammalian Cells. Pham H, Kearns NA, Maehr R Methods Mol Biol. 2016;1358:43-57. doi: 10.1007/978-1-4939-3067-8_3.
ID Plasmid Gene/Insert Vector Type Publication Hidden Extra Search Info  
50915pHAGE TRE dCas9dCas9 (Other)Mammalian Expression, Lentiviral, CRISPRCas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells. Development. 2014 Jan;141(1):219-23. doi: 10.1242/dev.103341. Tet-regulatable dCas9 lentiviral expression vector pHAGE Add to Cart
50916pHAGE TRE dCas9-VP64dCas9 (Other)Mammalian Expression, Lentiviral, CRISPRCas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells. Development. 2014 Jan;141(1):219-23. doi: 10.1242/dev.103341. Tet-regulatable dCas9-VP64 lentiviral expression vector pHAGE Add to Cart
50917pHAGE TRE dCas9-KRABdCas9 (Other)Mammalian Expression, Lentiviral, CRISPRCas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells. Development. 2014 Jan;141(1):219-23. doi: 10.1242/dev.103341. Tet-regulatable dCas9-KRAB lentiviral expression vector pHAGE Add to Cart
50918pHAGE EF1α dCas9-VP64dCas9 (Other)Mammalian Expression, Lentiviral, CRISPRCas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells. Development. 2014 Jan;141(1):219-23. doi: 10.1242/dev.103341. Constitutive dCas9-VP64 lentiviral expression vector pHAGE Add to Cart
50919pHAGE EF1α dCas9-KRABdCas9 (Other)Mammalian Expression, Lentiviral, CRISPRCas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells. Development. 2014 Jan;141(1):219-23. doi: 10.1242/dev.103341. Constitutive dCas9-KRAB lentiviral expression vector pHAGE Add to Cart
50920pLKO.1-puro U6 sgRNA BfuAI stufferMammalian Expression, Lentiviral, CRISPRCas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells. Development. 2014 Jan;141(1):219-23. doi: 10.1242/dev.103341. U6 driven sgRNA cloning vector where guide sequences are inserted between BfuAI sites pLKO.1 Add to Cart
50921pLKO.1-puro U6 sgRNA Oct4A -12Oct4A -12 sgRNA (Homo sapiens)Mammalian Expression, Lentiviral, CRISPRCas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells. Development. 2014 Jan;141(1):219-23. doi: 10.1242/dev.103341. U6 driven sgRNA targeting OCT4 isoform A -12 bp from TSS pLKO.1 POU5F1 OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4 Add to Cart
50922pLKO.1-puro U6 sgRNA Oct4A -158Oct4A -158 sgRNA (Homo sapiens)Mammalian Expression, Lentiviral, CRISPRCas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells. Development. 2014 Jan;141(1):219-23. doi: 10.1242/dev.103341. U6 driven sgRNA targeting OCT4 isoform A -158 bp from TSS pLKO.1 POU5F1 OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4 Add to Cart
50923pLKO.1-puro U6 sgRNA SOX17 -91Sox17 -91 sgRNA (Homo sapiens)Mammalian Expression, Lentiviral, CRISPRCas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells. Development. 2014 Jan;141(1):219-23. doi: 10.1242/dev.103341. U6 driven sgRNA targeting Sox17 -91 bp from TSS pLKO.1 SOX17 VUR3 Add to Cart
50924pLKO.1-puro U6 sgRNA SOX17 -126Sox17 -126 sgRNA (Homo sapiens)Mammalian Expression, Lentiviral, CRISPRCas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells. Development. 2014 Jan;141(1):219-23. doi: 10.1242/dev.103341. U6 driven sgRNA targeting Sox17 -126 bp from TSS pLKO.1 SOX17 VUR3 Add to Cart
50925pLKO.1-puro U6 sgRNA SOX17 -177Sox17 -177 sgRNA (Homo sapiens)Mammalian Expression, Lentiviral, CRISPRCas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells. Development. 2014 Jan;141(1):219-23. doi: 10.1242/dev.103341. U6 driven sgRNA targeting Sox17 -177 bp from TSS pLKO.1 SOX17 VUR3 Add to Cart
50926pLKO.1-puro U6 sgRNA SOX17 -296Sox17-296 sgRNA (Homo sapiens)Mammalian Expression, Lentiviral, CRISPRCas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells. Development. 2014 Jan;141(1):219-23. doi: 10.1242/dev.103341. U6 driven sgRNA targeting Sox17 -296 bp from TSS pLKO.1 SOX17 VUR3 Add to Cart
50927pLKO.1-puro U6 sgRNA CAGnegative control sgRNA (Other)Mammalian Expression, Lentiviral, CRISPRCas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells. Development. 2014 Jan;141(1):219-23. doi: 10.1242/dev.103341. U6 driven sgRNA negative control pLKO.1 Add to Cart
62205pLenti SpBsmBI sgRNA HygroMammalian Expression, LentiviralTranscriptional Regulation with CRISPR/Cas9 Effectors in Mammalian Cells. Methods Mol Biol. 2016;1358:43-57. doi: 10.1007/978-1-4939-3067-8_3. An empty sgRNA expression vector for expression of sgRNA for Sp Cas9 pLV Add to Cart
62207pLenti SpBsmBI sgRNA PuroMammalian Expression, LentiviralTranscriptional Regulation with CRISPR/Cas9 Effectors in Mammalian Cells. Methods Mol Biol. 2016;1358:43-57. doi: 10.1007/978-1-4939-3067-8_3. An empty sgRNA expression vector for expression of sgRNA for Sp Cas9 pLV Add to Cart