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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor.
Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS, Anderson MJ, Arden KC, Blenis J, Greenberg ME
Cell 1999 Mar 19;96(6):857-68.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
1787HA-FOXO3a WT
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1788HA-FOXO3a TM
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1789FHRE-LucReporter plasmid for FOXO3a. Forkhead responsive element with luciferase readout.
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1790GST-FOXO3a WT
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8348HA-FOXO3A T32A
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8349HA-FOXO3A S253A
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8350HA-FOXO3A S315A
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8351GST-FOXO3a TM 1-506aa
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10826GST-FOXO3a 1-506aa
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Antibodies from Article