Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor.
Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS, Anderson MJ, Arden KC, Blenis J, Greenberg ME
Cell 1999 Mar 19;96(6):857-68. PubMed Article
Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS, Anderson MJ, Arden KC, Blenis J, Greenberg ME
Cell 1999 Mar 19;96(6):857-68. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 1787 | HA-FOXO3a WT | |
| 1788 | HA-FOXO3a TM | |
| 1789 | FHRE-Luc | Reporter plasmid for FOXO3a. Forkhead responsive element with luciferase readout. |
| 1790 | GST-FOXO3a WT | |
| 8348 | HA-FOXO3A T32A | |
| 8349 | HA-FOXO3A S253A | |
| 8350 | HA-FOXO3A S315A | |
| 8351 | GST-FOXO3a TM 1-506aa | |
| 10826 | GST-FOXO3a 1-506aa |