The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation.
Angers S, Thorpe CJ, Biechele TL, Goldenberg SJ, Zheng N, MacCoss MJ, Moon RT
Nat Cell Biol. 2006 Apr . 8(4):348-57. PubMed Article
Angers S, Thorpe CJ, Biechele TL, Goldenberg SJ, Zheng N, MacCoss MJ, Moon RT
Nat Cell Biol. 2006 Apr . 8(4):348-57. PubMed Article
Plasmids from Article
ID | Plasmid | Purpose | |
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15100 | V51 pIRESpuro-GLUE (pGLUE) | tandem-affinity purification plasmid; streptavidin-(streptag) and calmodulin-(CBP) binding affinity tags |
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15101 | M76 pIRESpuro-GLUE-hDsh2 |
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15102 | M77 pIRESpuro-GLUE-hDsh3 |
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