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Directed evolution of key residues in fluorescent protein inverses the polarity of voltage sensitivity in the genetically-encoded indicator ArcLight.
Platisa J, Vasan G, Yang A, Pieribone VA
ACS Chem Neurosci. 2017 Jan 3. doi: 10.1021/acschemneuro.6b00234.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
74216CMV Marina-T2A-nls-mCherrygenetically-encoded fluorescent voltage indicator
85803CMV epArcLightgenetically-encoded fluorescent voltage indicator
85806CMV ArcLightCo (Q239)-T2A-nls-mCherryGenetically encoded voltage sensor ArcLight- codon optimized
85843hSyn Marina-T2A-nls-mCherrygenetically-encoded fluorescent voltage indicator
85844hSyn ArcLightCo (Q239)-T2A-nls-mCherryGenetically encoded voltage sensor ArcLight- codon optimized

Antibodies from Article