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ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain.
Conicella AE, Zerze GH, Mittal J, Fawzi NL
Structure. 2016 Sep 6;24(9):1537-49. doi: 10.1016/j.str.2016.07.007. Epub 2016 Aug 18.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
98669TDP-43_CTDExpresses 6xHis-tagged C-terminal domain of TDP-43
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98670TDP-43_CTD_A321GExpresses 6xHis-tagged C-terminal domain of TDP-43 with A321G
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98671TDP-43_CTD_A321VExpresses 6xHis-tagged C-terminal domain of TDP-43 with A321V
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98672TDP-43_CTD_A326PExpresses 6xHis-tagged C-terminal domain of TDP-43 with A326P
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98673TDP-43_CTD_Q331KExpresses 6xHis-tagged C-terminal domain of TDP-43 with Q331K
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98674TDP-43_CTD_M337VExpresses 6xHis-tagged C-terminal domain of TDP-43 with M337V
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98675TDP-43_CTD_M337PExpresses 6xHis-tagged C-terminal domain of TDP-43 with M337P
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98676TDP-43_CTD_del321-343Expresses 6xHis-tagged C-terminal domain of TDP-43 with a deletion of AA 321-343
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Antibodies from Article