Optimization of the mevalonate-based isoprenoid biosynthetic pathway in Escherichia coli for production of the anti-malarial drug precursor amorpha-4,11-diene.
Anthony JR, Anthony LC, Nowroozi F, Kwon G, Newman JD, Keasling JD
Metab Eng. 2009 Jan;11(1):13-9. doi: 10.1016/j.ymben.2008.07.007. Epub 2008 Aug 12. PubMed Article
Anthony JR, Anthony LC, Nowroozi F, Kwon G, Newman JD, Keasling JD
Metab Eng. 2009 Jan;11(1):13-9. doi: 10.1016/j.ymben.2008.07.007. Epub 2008 Aug 12. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 100167 | Keasling-2187 | Used to improve production from engineered biosynthetic pathways include optimizing codon usage, enhancing production of rate-limiting enzymes, and eliminating the accumulation of toxic intermediates or byproducts to improve cell growth |
| 100168 | Keasling-2337 | Used to improve production from engineered biosynthetic pathways include optimizing codon usage, enhancing production of rate-limiting enzymes, and eliminating the accumulation of toxic intermediates or byproducts to improve cell growth |
| 100169 | JBEI-3716 | Used to improve production from engineered biosynthetic pathways include optimizing codon usage, enhancing production of rate-limiting enzymes, and eliminating the accumulation of toxic intermediates or byproducts to improve cell growth |