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A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease.
Rocchi A, Yamamoto S, Ting T, Fan Y, Sadleir K, Wang Y, Zhang W, Huang S, Levine B, Vassar R, He C
PLoS Genet. 2017 Aug 14;13(8):e1006962. doi: 10.1371/journal.pgen.1006962. eCollection 2017 Aug.
PubMed

Plasmids from Article

ID Plasmid Purpose  
99505lenti-HA-mBec13rd generation lentiviral expression of wild-type Becn1
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99506lenti-HA-mBec1 F121ALentiviral expression of mutant Becn1 leading to hyperactive autophagy
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Antibodies from Article