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Unexpected binding behaviors of bacterial Argonautes in human cells cast doubts on their use as targetable gene regulators.
O'Geen H, Ren C, Coggins NB, Bates SL, Segal DJ
PLoS One. 2018 Mar 27;13(3):e0193818. doi: 10.1371/journal.pone.0193818. eCollection 2018.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
104383pCDNA-hTtAgohuman codon optimized TtAgo; pCDNA3 vector backbone, mammalian expression
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104384pCDNA-hNgAgohuman codon optimized NgAgo; pCDNA3 vector backbone, mammalian expression
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Antibodies from Article