Bi-allelic Loss of CDKN2A Initiates Melanoma Invasion via BRN2 Activation.
Zeng H, Jorapur A, Shain AH, Lang UE, Torres R, Zhang Y, McNeal AS, Botton T, Lin J, Donne M, Bastian IN, Yu R, North JP, Pincus L, Ruben BS, Joseph NM, Yeh I, Bastian BC, Judson RL
Cancer Cell. 2018 Jul 9;34(1):56-68.e9. doi: 10.1016/j.ccell.2018.05.014. PubMed Article
Zeng H, Jorapur A, Shain AH, Lang UE, Torres R, Zhang Y, McNeal AS, Botton T, Lin J, Donne M, Bastian IN, Yu R, North JP, Pincus L, Ruben BS, Joseph NM, Yeh I, Bastian BC, Judson RL
Cancer Cell. 2018 Jul 9;34(1):56-68.e9. doi: 10.1016/j.ccell.2018.05.014. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 110728 | pHIV-INK4A-zsGreen | Mammalian Expression of p16INK4A IRES zsGreen |
| 110729 | pHIV-ARF-zsGreen | Mammalian Expression of p14ARF IRES zsGreen |
| 110730 | pHIV-INK4A-mOrange2 | Mammalian Expression of p16INK4A IRES H2B-mOrange2 |
| 110731 | pHIV-ARF-mOrange2 | Mammalian Expression of p14ARF IRES H2B-mOrange2 |
| 110732 | pHIV-BRAFV600E-mOrange2 | Mammalian Expression of BRAFV600E IRES H2B-mOrange2 |
| 110733 | pGL410-BRN2p | Luciferase reporter for the human BRN2 promoter |
| 110734 | pHDR-CDKN2A-Ex2-CMV-EGFP | Recombination template for replacing CDKN2A Exon2 with CMV-EGFP |
| 110735 | pHDR-CDKN2A-Ex2-CMV-H2B-mOrange2 | Recombination template for replacing CDKN2A Exon2 with Ef1alpha-H2B-mOrange2 |
| 110736 | pEN35-CDKN2A-Ex2-L | Encodes Cas9 nickase and gRNA targeting CDKN2A Exon2 |
| 110737 | pEN35-CDKN2A-Ex2-R | Encodes Cas9 nickase and gRNA targeting CDKN2A Exon2 |