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Adenine base editing in mouse embryos and an adult mouse model of Duchenne muscular dystrophy.
Ryu SM, Koo T, Kim K, Lim K, Baek G, Kim ST, Kim HS, Kim DE, Lee H, Chung E, Kim JS
Nat Biotechnol. 2018 Jul;36(6):536-539. doi: 10.1038/nbt.4148. Epub 2018 Apr 27. PubMed Article

Plasmids from Article

ID Plasmid Purpose
112734pAAV-ABE-NT-sgRNAAAV inverted terminal repeat based vector plasmid encoding E. coli TadA, the N-terminal half of nCas9 and sgRNA
112876pAAV-ABE-CTAAV inverted terminal repeat based vector plasmid encoding the C-terminal half of nCas9
113128p3s-ABE7.10expressing ABE7.10 (TadA-TadA*7.10-nCas9-NLS-HA), human codon optimized

Antibodies from Article