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RNase H2, mutated in Aicardi-Goutieres syndrome, promotes LINE-1 retrotransposition.
Benitez-Guijarro M, Lopez-Ruiz C, Tarnauskaite Z, Murina O, Mian Mohammad M, Williams TC, Fluteau A, Sanchez L, Vilar-Astasio R, Garcia-Canadas M, Cano D, Kempen MH, Sanchez-Pozo A, Heras SR, Jackson AP, Reijns MA, Garcia-Perez JL
EMBO J. 2018 Aug 1;37(15). pii: embj.201798506. doi: 10.15252/embj.201798506. Epub 2018 Jun 29.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
119745pMSCVpuro-DESTAllows Gateway cloning of gene of interest into retroviral pMSCV vector (with Puromycin resistance)
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Antibodies from Article