Base editors for simultaneous introduction of C-to-T and A-to-G mutations.
Sakata RC, Ishiguro S, Mori H, Tanaka M, Tatsuno K, Ueda H, Yamamoto S, Seki M, Masuyama N, Nishida K, Nishimasu H, Arakawa K, Kondo A, Nureki O, Tomita M, Aburatani H, Yachie N
Nat Biotechnol. 2020 Jun 1. pii: 10.1038/s41587-020-0509-0. doi: 10.1038/s41587-020-0509-0. PubMed Article
Sakata RC, Ishiguro S, Mori H, Tanaka M, Tatsuno K, Ueda H, Yamamoto S, Seki M, Masuyama N, Nishida K, Nishimasu H, Arakawa K, Kondo A, Nureki O, Tomita M, Aburatani H, Yachie N
Nat Biotechnol. 2020 Jun 1. pii: 10.1038/s41587-020-0509-0. doi: 10.1038/s41587-020-0509-0. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 131124 | pRS0045 | Mammalian Target-ACE expression vector |
| 131125 | pRS0035 | Mammalian Target-AID expression vector |
| 131126 | pLV-SI-121 | A-to-G base editing reporter |
| 131127 | pLV-SI-112 | C-to-T base editing reporter |
| 131130 | pSI-535 | gRNA expression vector for C-to-T base editing reporter |
| 131131 | pSI-359 | gRNA expression vector for A-to-G base editing reporter |
| 139105 | pCMV-Target-ACEmax | Mammalian Target-ACEmax expression vector (pSI-625) |
| 139106 | pCMV-ACBEmax | Mammalian ACBEmax expression vector (pSI-632) |
| 139107 | pCMV-Target-AIDmax | Mammalian Target-AIDmax expression vector (pSI-626) |