Age-dependent accumulation of oligomeric SNCA/alpha-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA).
Ho PW, Leung CT, Liu H, Pang SY, Lam CS, Xian J, Li L, Kung MH, Ramsden DB, Ho SL
Autophagy. 2019 Apr 14:1-24. doi: 10.1080/15548627.2019.1603545. PubMed Article
Ho PW, Leung CT, Liu H, Pang SY, Lam CS, Xian J, Li L, Kung MH, Ramsden DB, Ho SL
Autophagy. 2019 Apr 14:1-24. doi: 10.1080/15548627.2019.1603545. PubMed Article
Plasmids from Article
ID | Plasmid | Purpose | |
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102361 | pcDNA3.1-hSNCA-NE | Overexpression of synuclein alpha in mammalian cells |
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102364 | pSIN-PAmCherry-mSNCA-NE | Lentiviral overexpression of PA-mCherry synuclein alpha fusion |
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102365 | pSIN-PAmCherry-KFERQ-NE | Lentiviral overexpression of PA-mCherry-KFERQ fusion |
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102366 | pSIN-hSNCA-NE | Lentiviral overexpression of synuclein alpha |
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