Genetic modification of primary human B cells to model high-grade lymphoma.
Caeser R, Di Re M, Krupka JA, Gao J, Lara-Chica M, Dias JML, Cooke SL, Fenner R, Usheva Z, Runge HFP, Beer PA, Eldaly H, Pak HK, Park CS, Vassiliou GS, Huntly BJP, Mupo A, Bashford-Rogers RJM, Hodson DJ
Nat Commun. 2019 Oct 4;10(1):4543. doi: 10.1038/s41467-019-12494-x. PubMed Article
Caeser R, Di Re M, Krupka JA, Gao J, Lara-Chica M, Dias JML, Cooke SL, Fenner R, Usheva Z, Runge HFP, Beer PA, Eldaly H, Pak HK, Park CS, Vassiliou GS, Huntly BJP, Mupo A, Bashford-Rogers RJM, Hodson DJ
Nat Commun. 2019 Oct 4;10(1):4543. doi: 10.1038/s41467-019-12494-x. PubMed Article
Plasmids from Article
ID | Plasmid | Purpose | |
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135305 | MSCV-BCL6-t2A-BCL2 | Overexpression of multiple human genes (BCL2 and BCL6) |
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135306 | MSCV-MYC-t2A-BCL2 | Overexpression of multiple human genes (BCL2 and MYC) |
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163611 | MSCV-BCL2 | Overexpression of human BCL2 |
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163612 | phCMV-GALV-MTR | Retro and Lentiviral transduction of primary human germinal center B cells |
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164662 | MSCV-Cas9-2A-BFP | Retroviral introduction of Cas9 into mammalian cell line coupled to expression of blue fluorescent protein |
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