Cytosine and adenine base editing of the brain, liver, retina, heart and skeletal muscle of mice via adeno-associated viruses.
Levy JM, Yeh WH, Pendse N, Davis JR, Hennessey E, Butcher R, Koblan LW, Comander J, Liu Q, Liu DR
Nat Biomed Eng. 2020 Jan;4(1):97-110. doi: 10.1038/s41551-019-0501-5. Epub 2020 Jan 14. PubMed Article
Levy JM, Yeh WH, Pendse N, Davis JR, Hennessey E, Butcher R, Koblan LW, Comander J, Liu Q, Liu DR
Nat Biomed Eng. 2020 Jan;4(1):97-110. doi: 10.1038/s41551-019-0501-5. Epub 2020 Jan 14. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 137171 | CMV_Npu-BE3.9max N-terminal | Expresses the N-terminal split-intein fragment of BE3.9max from the CMV promoter |
| 137172 | CMV_Npu-BE3.9max C-terminal | Expresses the C-terminal split-intein fragment of BE3.9max from the CMV promoter |
| 137173 | CMV_Npu-ABEmax N-terminal | Expresses the N-terminal split-intein fragment of ABEmax from the CMV promoter |
| 137174 | CMV_Npu-ABEmax C-terminal | Expresses the C-terminal split-intein fragment of ABEmax from the CMV promoter |
| 137175 | Cbh_v5 AAV-CBE N-terminal | AAV genome: expresses the N-terminal of v5 AAV-CBE from the Cbh promoter, and U6-sgRNA |
| 137176 | Cbh_v5 AAV-CBE C-terminal | AAV genome: expresses the C-terminal of v5 AAV-CBE from the Cbh promoter, and U6-sgRNA |
| 137177 | Cbh_v5 AAV-ABE N-terminal | AAV genome: expresses the N-terminal of v5 AAV-ABE from the Cbh promoter |
| 137178 | Cbh_v5 AAV-ABE C-terminal | AAV genome: expresses the C-terminal of v5 AAV-ABE from the Cbh promoter, and U6-sgRNA |
| 137179 | CMV_Npu-saBE3.9max N-terminal | Expresses the N-terminal split-intein fragment of S. aureus BE3.9max from the CMV promoter |
| 137180 | CMV_Npu-saBE3.9max C-terminal | Expresses the C-terminal split-intein fragment of S. aureus BE3.9max from the CMV promoter |
| 137181 | CMV_Npu-saBE3.9max_KKH C-terminal | Expresses the C-terminal split-intein fragment of S. aureus BE3.9max (KKH variant) from the CMV promoter |
| 137182 | Cbh_v5 AAV-saCBE N-terminal | AAV genome: expresses the N-terminal of S. aureus v5 AAV-CBE from the Cbh promoter, U6-sgRNA |
| 137183 | Cbh_v5 AAV-saCBE C-terminal | AAV genome: expresses the C-terminal of S. aureus v5 AAV-CBE from the Cbh promoter, and U6-sgRNA |
| 137184 | Cbh_v5 AAV-saCBE_KKH C-terminal | AAV genome: expresses the C-terminal of S. aureus v5 AAV-CBE, and U6-sgRNA (KKH variant). |