An engineered ScCas9 with broad PAM range and high specificity and activity.
Chatterjee P, Jakimo N, Lee J, Amrani N, Rodriguez T, Koseki SRT, Tysinger E, Qing R, Hao S, Sontheimer EJ, Jacobson J
Nat Biotechnol. 2020 May 11. pii: 10.1038/s41587-020-0517-0. doi: 10.1038/s41587-020-0517-0. PubMed Article
Chatterjee P, Jakimo N, Lee J, Amrani N, Rodriguez T, Koseki SRT, Tysinger E, Qing R, Hao S, Sontheimer EJ, Jacobson J
Nat Biotechnol. 2020 May 11. pii: 10.1038/s41587-020-0517-0. doi: 10.1038/s41587-020-0517-0. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 155011 | Sc++ | Expresses the codon-optimized, engineered Sc++ Cas9 nuclease in mammalian cells |