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TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends.
Zhong FL, Batista LF, Freund A, Pech MF, Venteicher AS, Artandi SE
Cell. 2012 Aug 3;150(3):481-94. doi: 10.1016/j.cell.2012.07.012.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
51631pCDH-3xFLAG-TERTMammalian expression of 3xFLAG tagged TERT, N-terminal.
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53585pCDNA-3xFLAG-NLS-TPP1Mammalian expression of 3xFLAG tagged, nuclear localized TPP1, N-terminal.
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79060pBABE-3xFLAG-NLS-TPP1-OBRetroviral expression of 3xFLAG tagged, nuclear localized wild-type TPP1-OB folding domain
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79061pBABE-3xFLAG-OB D166RRetroviral expression of 3xFLAG tagged, nuclear localized TPP1-OB-RR folding domain
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Antibodies from Article