AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA.
Fernandes-Alnemri T, Yu JW, Datta P, Wu J, Alnemri ES
Nature. 2009 Mar 26;458(7237):509-13. doi: 10.1038/nature07710. Epub 2009 Jan 21. PubMed Article
Fernandes-Alnemri T, Yu JW, Datta P, Wu J, Alnemri ES
Nature. 2009 Mar 26;458(7237):509-13. doi: 10.1038/nature07710. Epub 2009 Jan 21. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 51522 | pET21a-hAIM2-deltaPYD | Express His6-tagged HIN domain of hAIM2 in bacteria |
| 51528 | pET21a-hAIM2-GST | Express GST-tagged hAIM2 in bacteria |
| 51531 | pET21a-hAIM2-PYD-GST | Express GST-tagged PYD of hAIM2 in bacteria |
| 51532 | pET21a-hAIM2-His6 | Express His6-tagged hAIM2 in bacteria |
| 51533 | pET21a-mAIM2-GST | Express GST-tagged mAIM2 in bacteria |
| 51534 | pET21a-mAIM2-deltaPYD-GST | Express GST-tagged HIN domain of mAIM2 in bacteria |
| 51535 | pET21a-mAIM2-deltaPYD | Express His6-tagged HIN domain of mAIM2 in bacteria |
| 51536 | pET21a-mAIM2-His6 | Express His6-tagged mAIM2 in bacteria |
| 51537 | pcDNA3-mAIM2-Flag | Express Flag-tagged mAIM2 in mammalian cells |
| 51538 | pcDNA3-hAIM2-T7 | Express T7-tagged hAIM2 in mammalian cells |
| 51539 | pcDNA3-hAIM2deltPYD-T7 | Express T7-tagged HIN domain of hAIM2 in mammalian cells |
| 51540 | pFlag-CMV2-mAIM2 | Express Flag-tagged mAIM2 in mammalian cells |
| 51541 | pEGFP-N1-T7-hAIM2 | Express T7 and GFP-tagged hAIM2 in mammalian cells |
| 51542 | pEGFP-N1-hAIM2 | Express GFP-tagged hAIM2 in mammalian cells |
| 51544 | pDsRed-monomer-hAIM2 | Express DsRed monomer-tagged hAIM2 in bacteria |
| 51608 | pMSCVpuro-T7-hAIM2-EGFP | Express T7 and GFP-tagged hAIM2 in mammalian cells |
| 51609 | pMSCVpuro-hAIM2-DsRed monomer | Express DsRed monomer-tagged hAIM2 in mammalian cells |
| 51610 | pMSCVpuro-mAIM2-PYD-EGFP | Express GFP-tagged PYD of mAIM2 in mammalian cells |
| 51666 | pRSCgfp-hAIM2 | Express GFP and hAIM2 in mammalian cells |
| 51667 | pMSCVpuro-Flag-mAIM2-EGFP | Express Flag and GFP-tagged mAIM2 in mammalian cells |