Screening with a novel cell-based assay for TAZ activators identifies a compound that enhances myogenesis in C2C12 cells and facilitates muscle repair in the muscle injury model.
Yang Z, Nakagawa K, Sarkar A, Maruyama J, Iwasa H, Bao Y, Ishigami-Yuasa M, Ito S, Kagechika H, Hata S, Nishina H, Abe S, Kitagawa M, Hata Y
Mol Cell Biol. 2014 Feb 18. PubMed Article
Yang Z, Nakagawa K, Sarkar A, Maruyama J, Iwasa H, Bao Y, Ishigami-Yuasa M, Ito S, Kagechika H, Hata S, Nishina H, Abe S, Kitagawa M, Hata Y
Mol Cell Biol. 2014 Feb 18. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 52083 | pLenti-EF-FH-TAZ-ires-blast | Lentiviral expression vector for TAZ with N-terminal FLAG and His tags |
| 52084 | pLenti-EF-FH-TAZ S89A-ires-blast | Lentiviral expression vector for TAZ S89A mutant with N-terminal FLAG and His tags |
| 52085 | pLenti-EmGFP-LATS2/1 KD | Lentiviral RNAi vector for knockdown of LATS2 and LATS1. Co-expresses EmGFP as reporter |